Histidine decarboxylase activity in fetal intrauterine growth-retarded rats.

abstract：BACKGROUND:Current tools to predict the severity of respiratory syncytial virus (RSV) infection might be improved by including immunological parameters. We hypothesized that a combination of inflammatory markers would differentiate between severe and mild disease in RSV-infected children. METHODS:Blood and nasopharyng...

journal_title：Pediatric research

authors： Brand HK,Ferwerda G,Preijers F,de Groot R,Neeleman C,Staal FJ,Warris A,Hermans PW

更新日期：2013-02-01 00:00:00

abstract：:Recent studies have shown 1,25(OH)2D3 receptor-mediated modulation of leukocyte proliferation, differentiation, and function. We examined the phagocytosis and killing of microorganisms by neutrophils and monocytes from five patients of three families with hereditary resistance to 1,25(OH)2D3. Phagocytosis of microorga...

journal_title：Pediatric research

authors： Etzioni A,Hochberg Z,Pollak S,Meshulam T,Zakut V,Tzehoval E,Keisari Y,Aviram I,Spirer Z,Benderly A

更新日期：1989-03-01 00:00:00

abstract：:This review article examines the National Institutes of Health's (NIH) overall budget and its pediatric research funding across three time periods: predoubling [fiscal year (FY) 1992-1997]; doubling (FY 1998-2003); and postdoubling (FY 2004-2009). The average annual NIH appropriations increased by 5.4%, 13.4%, and 1.3...

journal_title：Pediatric research

authors： Gitterman DP,Hay WW Jr

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Necrotizing enterocolitis is characterized by intestinal inflammation and epithelial barrier dysfunction. Mitogen-activated protein kinase (MAPK) phosphatase (MKP)-1 plays a pivotal role in the feedback control of MAPK signaling, which regulates inflammation and apoptosis. We hypothesized that MKP-1 prevents...

journal_title：Pediatric research

authors： Talavera MM,Kralik N,Jin Y,Chen B,Liu Y,Nelin LD

更新日期：2015-08-01 00:00:00

abstract：:The widespread use of phototherapy for neonatal hyperbilirubinemia has caused some concern since substances other than bilirubin may be photoactivated. The toxic properties of these photoactivated substances might prove to be more harmful to the neonatal infant than bilirubin. The purpose of the present study was to i...

journal_title：Pediatric research

authors： Speck WT,Chen CC,Rosenkranz HS

更新日期：1975-03-01 00:00:00

abstract：:Sarcoplasmic reticulum (SR) Ca release has been shown not to be the predominant mechanism responsible for excitation-contraction (E-C) coupling in fetal myocytes. However, most of the studies have been conducted either on primary cultures or acutely isolated cells, in which an apparent reduction of ryanodine receptor ...

journal_title：Pediatric research

authors： Takizawa M,Ishiwata T,Kawamura Y,Kanai T,Kurokawa T,Nishiyama M,Ishida H,Asano Y,Nonoyama S

更新日期：2011-04-01 00:00:00

abstract：:In the human fetus, liver macrophages appear to be the primary source of erythropoietin (Epo). Epo production shifts from the liver to peritubular cells in the kidney sometime during the 3rd trimester. Some preterm infants experience a hyporegenerative anemia that appears to be caused by inadequate Epo production. It ...

journal_title：Pediatric research

authors： Ohls RK,Li Y,Trautman MS,Christensen RD

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:The associations between prenatal exposure to endocrine disruptive chemicals (EDCs) and fetal growth are inconsistent, and few studies have considered small-for-gestational-age (SGA) birth as an outcome. Our current study of Scandinavian parous women aimed to address these inconsistencies and gaps in the lit...

journal_title：Pediatric research

authors： Lauritzen HB,Larose TL,Øien T,Sandanger TM,Odland JØ,van de Bor M,Jacobsen GW

更新日期：2017-01-01 00:00:00

abstract：:Iron is essential for fetal organ development, but the effect of isolated iron deficiency on nephrogenesis is unknown. Human premature infants are at risk for disrupted nephrogenesis because glomerular development is incomplete until 36-wk gestation. We modeled the effects of iron on postnatal glomerulogenesis in four...

journal_title：Pediatric research

authors： Drake KA,Sauerbry MJ,Blohowiak SE,Repyak KS,Kling PJ

更新日期：2009-12-01 00:00:00

abstract：:BackroundMicrocephaly can either be isolated or it may coexist with other neurological entities and/or multiple congenital anomalies, known as syndromic microcephaly. Although many syndromic cases can be classified based on the characteristic phenotype, some others remain uncertain and require further investigation. T...

journal_title：Pediatric research

authors： Tsoutsou E,Tzetis M,Giannikou K,Braoudaki M,Mitrakos A,Amenta S,Selenti N,Kanavakis E,Zafeiriou D,Kitsiou-Tzeli S,Fryssira H

更新日期：2017-08-01 00:00:00

abstract：:Children with inflammatory bowel disease are known to be at risk of osteopenia. The cause of this osteopenia is likely to be multifactorial, but the inflammatory process with its characteristic overproduction of cytokines has been implicated. To investigate this possible contribution of the disease activity to the dev...

journal_title：Pediatric research

authors： Harbour ME,Gregory JW,Jenkins HR,Evans BA

更新日期：2000-08-01 00:00:00

abstract：:Evidence is inconsistent or poorly understood for links between polychlorinated biphenyls (PCBs), 1,1'-dichloro-2,2'-bis(4-chlorophenyl)ethylene (DDE), and organophosphate (OP) pesticides and adverse pregnancy outcomes, although they are known developmental toxicants. We measured biomarkers of maternal exposure to DDE...

journal_title：Pediatric research

authors： Wolff MS,Engel S,Berkowitz G,Teitelbaum S,Siskind J,Barr DB,Wetmur J

更新日期：2007-02-01 00:00:00

abstract：:Genetic factors are implicated in pathogenesis of neonatal hyperbilirubinemia. In this nested case-control study, we determined 1) frequency of thymine-adenine (TA)n promoter polymorphism and Gly71Arg mutation in uridine diphosphoglucuronate-glucuronosyltransferase 1A1 (UGT1A1) gene in neonates > or =35-wk gestation p...

journal_title：Pediatric research

authors： Agrawal SK,Kumar P,Rathi R,Sharma N,DAS R,Prasad R,Narang A

更新日期：2009-06-01 00:00:00

abstract：:After an initial postnatal diuresis, neonates are in positive sodium balance. Because atrial natriuretic peptide (ANP) contributes to sodium homeostasis, this study was designed to evaluate the maturational effects of increased dietary sodium intake on cardiac ANP production. Preweaned Sprague-Dawley rat pups were art...

journal_title：Pediatric research

authors： Muchant DG,Belmonte DC,Garmey MJ,Baertschi AJ,Pence RA,Chevalier RL

更新日期：1995-03-01 00:00:00

abstract：:Our goal was to determine the relationship between 4 amniotic fluid (AF) proteomic biomarkers (human neutrophil defensins 2 and 1, calgranulins C and A) characteristic of intra-amniotic inflammation, and funisitis and early-onset sepsis in premature neonates. The mass restricted (MR) score was generated from AF obtain...

journal_title：Pediatric research

authors： Buhimschi CS,Buhimschi IA,Abdel-Razeq S,Rosenberg VA,Thung SF,Zhao G,Wang E,Bhandari V

更新日期：2007-03-01 00:00:00

abstract：:Thrombocytopenia in the first days of life, in association with evidence of reduced megakaryocytopoiesis and platelet production at birth, is common in sick preterm babies. Thrombopoietin (Tpo) is the major regulator of platelet production in adults. However, these babies have low Tpo levels at birth, suggesting that ...

journal_title：Pediatric research

authors： Watts TL,Murray NA,Roberts IA

更新日期：1999-07-01 00:00:00

abstract：:This study characterizes cardiorespiratory dysregulation in young girls with MECP2 mutation-confirmed Rett syndrome (RS). Respiratory inductance plethysmography of chest/abdomen and ECG was obtained during daytime wakefulness in 47 girls with MECP2 mutation-confirmed RS and 47 age-, gender-, and ethnicity-matched cont...

journal_title：Pediatric research

authors： Weese-Mayer DE,Lieske SP,Boothby CM,Kenny AS,Bennett HL,Silvestri JM,Ramirez JM

更新日期：2006-10-01 00:00:00

abstract：:The worldwide burden of disease due to Epstein-Barr virus (EBV) infection is enormous. Diseases include endemic Burkitt lymphoma, infectious mononucleosis, cancers after transplantation, Hodgkin lymphoma, and nasopharyngeal carcinoma. A prophylactic EBV vaccine has the potential to significantly reduce the incidence a...

journal_title：Pediatric research

authors： Balfour HH Jr,Schmeling DO,Grimm-Geris JM

更新日期：2020-01-01 00:00:00

abstract：:The etiology of the tall stature almost invariably seen in homocystinuric patients is not known. The effect of metabolic control and the role of the GH-IGF system on growth were investigated in 10 patients with homocystinuria. There was a direct correlation between the plasma free homocyst(e)ine and growth velocity SD...

journal_title：Pediatric research

authors： Topaloglu AK,Sansaricq C,Snyderman SE

更新日期：2001-06-01 00:00:00

abstract：:Pregnane steroids have sedative and neuroprotective effects on the brain, due to interactions with the steroid-binding site of the GABAA receptor. In the adult brain, synthesis of the pregnane steroids is increased in response to stress. Therefore, we have used umbilicoplacental embolization to mimic chronic placental...

journal_title：Pediatric research

authors： Nguyen PN,Billiards SS,Walker DW,Hirst JJ

更新日期：2003-12-01 00:00:00

abstract：:Blood mononuclear cells from newborns and from adults, immune or nonimmune to herpes simplex virus, were cultured with IL 2 and herpes simplex virus and the amount of gamma-interferon in the supernatant measured after 3 days. The newborn and nonimmune adult cells made equivalent trace amounts of gamma-interferon in cu...

journal_title：Pediatric research

authors： Hayward AR,Herberger M,Saunders D

更新日期：1986-05-01 00:00:00

abstract：:Amplitude-integrated EEG (aEEG) is used to select patients for neuroprotective therapy after perinatal asphyxia because of its prognostic accuracy within several hours after birth. We aimed to determine the natural course of aEEG patterns during the first 72 h of life, in relation to neurologic outcome, in a group of ...

journal_title：Pediatric research

authors： ter Horst HJ,Sommer C,Bergman KA,Fock JM,van Weerden TW,Bos AF

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:The prevalence of autism spectrum disorders (ASD) is 5-fold higher in preterm (PT) infants born ≤28 weeks gestational age (GA) as compared to the general population. The relationship between placental pathologic lesions and ASD in PT infants has not been studied. OBJECTIVES:The objective of this study was t...

journal_title：Pediatric research

authors： Mir IN,White SP,Steven Brown L,Heyne R,Rosenfeld CR,Chalak LF

更新日期：2020-09-19 00:00:00

abstract：BACKGROUND:Regular physical activity provides children with health and developmental benefits. This study investigated if active play and walking with the family dog was associated with better social-emotional development in young children. METHODS:We surveyed 1646 parents to ascertain if families with pre-schoolers o...

journal_title：Pediatric research

authors： Wenden EJ,Lester L,Zubrick SR,Ng M,Christian HE

更新日期：2020-07-06 00:00:00

abstract：:The ontogenetic renal responsiveness to exogenous cortisol was examined in the chronically cannulated ovine fetus. The contribution of effects at proximal and distal tubule of the kidney were studied also. Cortisol (81.5 micrograms/h) was infused into immature ovine fetuses (mean gestational age -113.9 days) on five o...

journal_title：Pediatric research

authors： Towstoless MK,McDougall JG,Wintour EM

更新日期：1989-07-01 00:00:00

abstract：:Uteroplacental insufficiency alters the anabolic metabolism of the fetus, resulting in intrauterine growth retardation (IUGR). The metabolic and physiologic factors that cause IUGR have long standing consequences after birth. Postnatal growth and glucose metabolism are altered in the IUGR infant. Skeletal muscle is an...

journal_title：Pediatric research

authors： Lane RH,Chandorkar AK,Flozak AS,Simmons RA

更新日期：1998-05-01 00:00:00

abstract：:The purpose of this investigation was to determine whether maximal oxygen consumption (VO2max) differed between two selected groups of black and white children and whether a difference existed to determine whether it was related to hematologic profiles, body composition, and/or physical activity/inactivity level. Fort...

journal_title：Pediatric research

authors： Andreacci JL,Robertson RJ,Dubé JJ,Aaron DJ,Balasekaran G,Arslanian SA

更新日期：2004-11-01 00:00:00

abstract：:We investigated the early postnatal changes of the mesenteric circulation and its relation to the systemic circulation in 15 preterm infants. The infants were studied before the first feeding on d 1 and pre- and postprandially on d 3, 4, 5, and 7. Blood flow velocity was measured by ultrasound Doppler in the superior ...

journal_title：Pediatric research

authors： Martinussen M,Brubakk AM,Vik T,Yao AC

更新日期：1996-02-01 00:00:00

abstract：:The metabolism of proteoglycans in normal growth plate and the changes in growth plate morphology induced by diabetes and malnutrition were studied in rats. The proteoglycans had a significantly faster turnover (half-life measured with [35S]sulfate labeling: 25-30 h) than the cells in the growth plate. Morphometric st...

journal_title：Pediatric research

authors： Axelsson I,Pita JC,Howell DS,Lorentzon R,Berman I,Boquist L

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Increasing numbers of preterm-born children survive nowadays, and improving long-term health and neurodevelopment is becoming more important. Early-life growth has been linked to neurodevelopmental outcomes. We aimed to study whether this association has changed with time. METHODS:We studied two cohorts of ...

journal_title：Pediatric research

authors： Ruys CA,Hollanders JJ,Bröring T,van Schie PEM,van der Pal SM,van de Lagemaat M,Lafeber HN,Rotteveel J,Finken MJJ

更新日期：2019-02-01 00:00:00