Serum oxalate microassay using chemiluminescence detection.

Abstract:

:Determination of serum oxalate concentration is important for the diagnosis and monitoring of hyperoxalurias, and extends to patients with all types of renal disease. Approximately 5 to 10 ml of blood is required for each test by conventional methods, and the test is not adapted for use in children. We developed a highly sensitive method that limits the volume of blood required for the test. This new and sensitive tool to detect H2O2 can be successfully substituted for the conventional, and expensive, colorimetric reaction to accurately analyze oxalate concentration.

journal_name

Kidney Int

journal_title

Kidney international

authors

Gaulier JM,Cochat P,Lardet G,Vallon JJ

doi

10.1038/ki.1997.505

subject

Has Abstract

pub_date

1997-12-01 00:00:00

pages

1700-3

issue

6

eissn

0085-2538

issn

1523-1755

pii

S0085-2538(15)60345-3

journal_volume

52

pub_type

  • Comparative effects of acetate and bicarbonate hemodialysis on left ventricular function.

    abstract::To assess the comparative effects of hemodialysis with acetate versus bicarbonate base on left ventricular systolic function, we performed M-mode echocardiography on 36 patients prior to and immediately following 4-hr maintenance hemodialysis. Patients were initially dialyzed against either sodium acetate or sodium bi...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.1985.78

    authors: Ruder MA,Alpert MA,Van Stone J,Selmon MR,Kelly DL,Haynie JD,Perkins SK

    更新日期:1985-05-01 00:00:00

  • Overexpression of exogenous kidney-specific Ngal attenuates progressive cyst development and prolongs lifespan in a murine model of polycystic kidney disease.

    abstract::Neutrophil gelatinase-associated lipocalin (Ngal) is a biomarker for acute and chronic renal injuries, including polycystic kidney disease (PKD). However, the effect of Ngal on PKD progression remains unexplored. To study this, we generated 3 strains of mice with different expression levels of Ngal within an establish...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1016/j.kint.2016.09.005

    authors: Wang E,Chiou YY,Jeng WY,Lin HK,Lin HH,Chin HJ,Leo Wang CK,Yu SS,Tsai SC,Chiang CY,Cheng PH,Lin HJ,Jiang ST,Chiu ST,Hsieh-Li HM

    更新日期:2017-02-01 00:00:00

  • Endostatin and transglutaminase 2 are involved in fibrosis of the aging kidney.

    abstract::Endostatin (EST), an antiangiogenic factor, is enriched in aging kidneys. EST is also an interactive partner of transglutaminase 2 (TG2), an enzyme that cross-links extracellular matrix proteins. Here we tested whether EST and TG2 play a role in the fibrosis of aging. In wild-type mice, aging kidneys exhibited a 2- to...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1016/j.kint.2016.01.030

    authors: Lin CH,Chen J,Zhang Z,Johnson GV,Cooper AJ,Feola J,Bank A,Shein J,Ruotsalainen HJ,Pihlajaniemi TA,Goligorsky MS

    更新日期:2016-06-01 00:00:00

  • Alloreactive T cells and 'the persistence of memory'.

    abstract::Circulating donor-reactive effector memory T cells have been associated with allograft injury in humans. The next step to translate this observation into clinical practice is the design of clinical trials aimed at individualization of T cell-targeted therapy. The administration of immunosuppressive therapy based on th...

    journal_title:Kidney international

    pub_type: 评论,杂志文章

    doi:10.1038/ki.2013.295

    authors: Poggio ED,Augustine JJ

    更新日期:2013-12-01 00:00:00

  • Endothelial cell adhesion molecule and PMNL response to inflammatory stimuli and AGE-modified fibronectin.

    abstract:BACKGROUND:Atherosclerotic vascular disease is the leading cause of death in patients with diabetes mellitus and end-stage renal disease. Advanced glycation end products (AGEs) are strongly suggested to be involved in the pathogenesis of atherosclerosis in these patients who also frequently experience infectious compli...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1046/j.1523-1755.1998.00157.x

    authors: Sengoelge G,Födinger M,Skoupy S,Ferrara I,Zangerle C,Rogy M,Hörl WH,Sunder-Plassmann G,Menzel J

    更新日期:1998-11-01 00:00:00

  • Partial biochemical and physicochemical characterization of organic macromolecules in urine from patients with renal stones and control subjects.

    abstract::From the urine of patients with calcium nephrolithiasis, and of control subjects, we isolated organic substances according to molecular size and tested them for effects on calcium oxalate precipitation. Nine subgroup materials of varying sizes were prepared by ultrafiltration and Sephadex G-200 column chromatography f...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.1982.33

    authors: Kitamura T,Zerwekh JE,Pak CY

    更新日期:1982-02-01 00:00:00

  • Dialysis costs: results of a diverse sample study.

    abstract::A study of dialysis costs in five major dialysis centers throughout the United States was conducted in 1973. When available, home, home training, limited care, satellite and in-hospital-full-care dialysis were included. The study's objective was to determine the cost per dialysis for each separate dialysis modality. A...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.1976.31

    authors: Hoffstein PA,Krueger KK,Wineman RJ

    更新日期:1976-03-01 00:00:00

  • Pressure diuresis and natriuresis in DOCA-salt mice.

    abstract::The increasing use of mice in renal and cardiovascular studies has necessitated adapting physiological methods used for rats to mice, which are far smaller in size. We have adapted measurements of continuous renal blood flow, pressure natriuresis and diuresis, and laser-Doppler cortical and medullary flow to 40 g mice...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.1997.462

    authors: Gross V,Lippoldt A,Luft FC

    更新日期:1997-11-01 00:00:00

  • Mortality prediction in stable hemodialysis patients is refined by YKL-40, a 40-kDa glycoprotein associated with inflammation.

    abstract::Chronic inflammation contributes to increased mortality in hemodialysis (HD) patients. YKL-40 is a novel marker of inflammation, tissue remodeling, and highly expressed in macrophages inside vascular lesions. Elevated levels of YKL-40 have been reported for HD patients but how it integrates into the proinflammatory me...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1016/j.kint.2017.07.010

    authors: Lorenz G,Schmalenberg M,Kemmner S,Haller B,Steubl D,Pham D,Schreiegg A,Bachmann Q,Schmidt A,Haderer S,Huber M,Angermann S,Günthner R,Braunisch M,Hauser C,Reichelt AL,Matschkal J,Suttmann Y,Moog P,Stock K,Küchle C

    更新日期:2018-01-01 00:00:00

  • Defining hypercalciuria in nephrolithiasis.

    abstract::The classic definition of hypercalciuria, an upper normal limit of 200  mg/day, is based on a constant diet restricted in calcium, sodium, and animal protein; however, random diet data challenge this. Here our retrospective study determined the validity of the classic definition of hypercalciuria by comparing data fro...

    journal_title:Kidney international

    pub_type: 杂志文章,meta分析,评审

    doi:10.1038/ki.2011.227

    authors: Pak CY,Sakhaee K,Moe OW,Poindexter J,Adams-Huet B,Pearle MS,Zerwekh JE,Preminger GM,Wills MR,Breslau NA,Bartter FC,Brater DC,Heller HJ,Odvina CV,Wabner CL,Fordtran JS,Oh M,Garg A,Harvey JA,Alpern RJ,Snyder WH,Pe

    更新日期:2011-10-01 00:00:00

  • Predicting renal survival in primary focal glomerulosclerosis from the time of presentation.

    abstract:UNLABELLED:Predicting renal survival in primary focal glomerulosclerosis from the time of presentation. BACKGROUND:To predict the risk of developing chronic renal failure in patients with primary focal glomerulosclerosis (FGS) using predictors available at the time of presentation, a retrospective analysis was perform...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/sj.ki.4491164

    authors: Chitalia VC,Wells JE,Robson RA,Searle M,Lynn KL

    更新日期:1999-12-01 00:00:00

  • Differing regulation and function of ICAM-1 and class II antigens on renal tubular cells.

    abstract::Intercellular adhesion molecule-1 (ICAM-1) and MHC class II (Ia) antigens are increased on proximal tubular epithelial cells (TEC) in autoimmune nephritis and transplant rejection. ICAM-1 is a member of the immunoglobulin gene superfamily that increases the avidity of T cell interactions with antigen-presenting cells ...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.1990.221

    authors: Jevnikar AM,Wuthrich RP,Takei F,Xu HW,Brennan DC,Glimcher LH,Rubin-Kelley VE

    更新日期:1990-09-01 00:00:00

  • Genomic and clinical profiling of a national nephrotic syndrome cohort advocates a precision medicine approach to disease management.

    abstract::Steroid Resistant Nephrotic Syndrome (SRNS) in children and young adults has differing etiologies with monogenic disease accounting for 2.9-30% in selected series. Using whole exome sequencing we sought to stratify a national population of children with SRNS into monogenic and non-monogenic forms, and further define t...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1016/j.kint.2016.10.013

    authors: Bierzynska A,McCarthy HJ,Soderquest K,Sen ES,Colby E,Ding WY,Nabhan MM,Kerecuk L,Hegde S,Hughes D,Marks S,Feather S,Jones C,Webb NJ,Ognjanovic M,Christian M,Gilbert RD,Sinha MD,Lord GM,Simpson M,Koziell AB,Welsh

    更新日期:2017-04-01 00:00:00

  • Visualization of renal autoregulation in the split hydronephrotic kidney of rats.

    abstract::The autoregulatory ability of the renal vascular system in the split hydronephrotic kidney was quantitated with intravital microscopy. The luminal diameters of the arcuate and interlobular arteries as well as the afferent and efferent arterioles were measured. Glomerular blood flow was determined by the dual slit tech...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.1989.104

    authors: Steinhausen M,Blum M,Fleming JT,Holz FG,Parekh N,Wiegman DL

    更新日期:1989-05-01 00:00:00

  • Localization of PDGF alpha-receptor in the developing and mature human kidney.

    abstract::Using in situ hybridization and immunocytochemistry we describe the renal localization of the PDGF alpha-receptor. PDGF alpha-receptor mRNA was uniformly present in human metanephric kidney in interstitial cells and vascular arcades that course through the blastema. PDGF alpha-receptor mRNA was present in some mesangi...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.1997.157

    authors: Floege J,Hudkins KL,Seifert RA,Francki A,Bowen-Pope DF,Alpers CE

    更新日期:1997-04-01 00:00:00

  • Effect of glycine on prelethal and postlethal increases in calpain activity in rat renal proximal tubules.

    abstract::The effect of glycine on hypoxia- and ionomycin-induced increases in calpain activity in rat proximal tubules was determined. Calpain activity was determined both in vitro and in the intact cell using the fluorescent substrate N-succinyl-Leu-Leu-Val-Tyr-7-amido-4-methyl coumarin (N-succinyl-Leu-Leu-Val-Tyr-AMC) and We...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.1997.452

    authors: Edelstein CL,Ling H,Gengaro PE,Nemenoff RA,Bahr BA,Schrier RW

    更新日期:1997-11-01 00:00:00

  • Prevalence and risk factors for microalbuminuria in a referred cohort of type II diabetic patients: a global perspective.

    abstract::We described the characteristics in a referred cohort of type II diabetic patients in the Developing Education on Microalbuminuria for Awareness of renal and cardiovascular risk in Diabetes study evaluating the global prevalence and determinants of microalbuminuria (MA). A cross-sectional study evaluating 32,208 type ...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/sj.ki.5000377

    authors: Parving HH,Lewis JB,Ravid M,Remuzzi G,Hunsicker LG,DEMAND investigators.

    更新日期:2006-06-01 00:00:00

  • Angiotensin II action in isolated microperfused rabbit afferent arterioles is modulated by flow.

    abstract::We have recently presented evidence that endogenous nitric oxide (NO) and prostaglandins (PGs) modulate angiotensin II (Ang II) action in microperfused afferent arterioles (Af-Arts). Because flow may be a physiological stimulus of endothelial release of NO and PGs, we tested the hypothesis that flow through the lumen ...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.1996.55

    authors: Juncos LA,Ren Y,Arima S,Garvin J,Carretero OA,Ito S

    更新日期:1996-02-01 00:00:00

  • The SAM domain of ANKS6 has different interacting partners and mutations can induce different cystic phenotypes.

    abstract::The ankyrin repeat and sterile α motif (SAM) domain-containing six gene (Anks6) is a candidate for polycystic kidney disease (PKD). Originally identified in the PKD/Mhm(cy/+) rat model of PKD, the disease is caused by a mutation (R823W) in the SAM domain of the encoded protein. Recent studies support the etiological r...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.2015.122

    authors: Bakey Z,Bihoreau MT,Piedagnel R,Delestré L,Arnould C,de Villiers Ad,Devuyst O,Hoffmann S,Ronco P,Gauguier D,Lelongt B

    更新日期:2015-08-01 00:00:00

  • Renal hemodynamics and segmental tubular reabsorption in early type 1 diabetes.

    abstract::To investigate mechanisms underlying GFR control in diabetes mellitus, renal hemodynamics and segmental tubular handling of sodium, using lithium clearance, were assessed in 41 insulin-dependent diabetics (IDD) treated by insulin for 11 +/- 8 days, and in 19 normal controls. Average GFR and effective renal plasma flow...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.1990.95

    authors: Hannedouche TP,Delgado AG,Gnionsahe DA,Boitard C,Lacour B,Grünfeld JP

    更新日期:1990-04-01 00:00:00

  • Numerous protein-bound solutes are cleared by the kidney with high efficiency.

    abstract::The kidney clears numerous solutes from the plasma; however, retention of these solutes causes uremic illness when the kidneys fail. We know remarkably little about which retained solutes are toxic and this limits our ability to improve dialysis therapies. To explore this, we employed untargeted mass spectrometry to i...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.2013.154

    authors: Sirich TL,Aronov PA,Plummer NS,Hostetter TH,Meyer TW

    更新日期:2013-09-01 00:00:00

  • PGF2 alpha activation of Na/H antiporter and ammoniagenesis in parent/variant LLC-PK1 cells.

    abstract::A novel variant of the LLC-PK1 cell line was used to examine directly the mechanism whereby PGF2 alpha and TPA inhibit renal ammoniagenesis. The variant cells, which exhibit a growth pattern and morphology similar to the parent cell line, were isolated by a self selection process utilizing long-term cultures of parent...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.1994.368

    authors: Sahai A,Fadda GZ,Sandler RS,Tannen RL

    更新日期:1994-10-01 00:00:00

  • Dietary sodium restriction prevents kidney damage in high fructose-fed rats.

    abstract::Sodium depletion has a protective effect on target-organ damage in hypertension independent of blood pressure. Here we tested whether chronic dietary sodium restriction may prevent the development of renal alterations associated with insulin resistance by reducing the inflammatory and oxidant state. Rats were fed norm...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.2012.478

    authors: Oudot C,Lajoix AD,Jover B,Rugale C

    更新日期:2013-04-01 00:00:00

  • Decreased ATPase activity in adriamycin nephrosis is independent of proteinuria.

    abstract::In previous studies from this laboratory it has been shown that ATP-ase activity in situ in the glomerular basement membrane (GBM) is clearly reduced in rats rendered nephrotic after treatment with adriamycin (ADR). The question was raised whether this reduction of ATP-ase activity in the GBM is due to toxic activity ...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.1987.55

    authors: Bakker WW,Kalicharan D,Donga J,Hulstaert CE,Hardonk MJ

    更新日期:1987-03-01 00:00:00

  • Identification of a single base insertion in the COL4A5 gene in Alport syndrome.

    abstract::We identified a novel mutation in the COL4A5 gene of a Japanese patient with Alport syndrome. A combination of in vitro amplification of the exons with single strand conformation polymorphisms (SSCP) analysis suggested the presence of a mutation in exon 48. Sequencing of the amplified DNA revealed a single base (T) in...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.1993.353

    authors: Nakazato H,Hattori S,Matsuura T,Koitabashi Y,Endo F,Matsuda I

    更新日期:1993-11-01 00:00:00

  • Gut microbiome and kidney stone disease: not just an Oxalobacter story.

    abstract::Intestinal regulation of oxalate absorption is a complex mechanism, not exclusively reliant on the oxalate-degrading anaerobe Oxalobacter formigenes. Using metagenomics, Miller et al. were able to describe a network of bacterial taxa co-occurring with Oxalobacter formigenes in fecal samples from non-stone forming cont...

    journal_title:Kidney international

    pub_type: 评论,杂志文章

    doi:10.1016/j.kint.2019.03.020

    authors: Ticinesi A,Nouvenne A,Meschi T

    更新日期:2019-07-01 00:00:00

  • Effect of mineralocorticoid replacement therapy on renal acid-base homeostasis in adrenalectomized patients.

    abstract::Chronic balance studies were performed in six adrenalectomized patients to investigate the renal and systemic acid-base consequences of mineralocorticoid deficiency in the absence of either glucocorticoid deficiency or parenchymal renal disease. Constant glucocorticoid replacement was provided with dexamethasone, 750 ...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1038/ki.1980.195

    authors: Sebastian A,Sutton JM,Hulter HN,Schambelan M,Poler SM

    更新日期:1980-12-01 00:00:00

  • Two channels for one job.

    abstract::The study by Rieg et al. is the first to examine potassium handling in BK(-/-) mice, thereby addressing many unanswered questions regarding the separate roles of BK and ROMK channels in renal potassium secretion. This Commentary is an interpretation and opinion of their results, by two researchers who have been studyi...

    journal_title:Kidney international

    pub_type: 评论,杂志文章

    doi:10.1038/sj.ki.5002438

    authors: Sansom SC,Welling PA

    更新日期:2007-09-01 00:00:00

  • Effects of ACE inhibition and bradykinin antagonism on cardiovascular changes in uremic rats.

    abstract:BACKGROUND:Cardiovascular death continues to be a major problem in renal failure. Structural abnormalities of the heart and the vasculature contribute to the increased cardiovascular risk. They are ameliorated by angiotensin-converting enzyme (ACE) inhibitors, but because of the nonspecifity of ACE inhibition, it is un...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1046/j.1523-1755.2000.00163.x

    authors: Amann K,Gassmann P,Buzello M,Orth SR,Törnig J,Gross ML,Magener A,Mall G,Ritz E

    更新日期:2000-07-01 00:00:00

  • Expression, regulation, and function of inhibitor of apoptosis family genes in rat mesangial cells.

    abstract:BACKGROUND:The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. The purpose of this investigation was to examine the expression, regulation, and function of IAP genes in cultured rat mesangial cells. METHODS:Basal and inducible expression of c-IAP1, c-IAP2, ...

    journal_title:Kidney international

    pub_type: 杂志文章

    doi:10.1046/j.1523-1755.2001.060002579.x

    authors: Furusu A,Nakayama K,Xu Q,Konta T,Sugiyama H,Kitamura M

    更新日期:2001-08-01 00:00:00