Bacterial overgrowth, intestinal transit, and nutrition after total gastrectomy. Comparison of a jejunal pouch with Roux-en-Y reconstruction in a prospective random study.

Abstract:

BACKGROUND:Jejunal pouches after total gastrectomy have been introduced to diminish postgastrectomy symptoms and improve nutrition. However, the effect of a pouch on the intestinal bacteriology and transit is controversial. METHODS:Bacterial overgrowth was measured with the glucose breath test and the mouth-to-caecum transit time (MCT) by means of the lactulose breath test after total gastrectomy and Roux-en-Y reconstruction in 24 patients with a pouch (Pouch group) and in 22 patients without a pouch (Roux-en-Y group). Postoperative symptoms were evaluated with a standard questionnaire, and nutrition was measured by blood chemistry and weight loss. RESULTS:MCTT was 110 +/- 44 min in the Roux-en-Y group and 117 +/- 44 min in the Pouch group (NS). Eighty-six per cent of the patients in the Roux-en-Y group and 91% of the patients in the Pouch group had bacterial overgrowth (NS). Transit time was shorter in patients with severe dumping than patients without dumping (60 +/- 28 min versus 115 +/- 41 min; P = 0.04). Maximal hydrogen concentration in the glucose breath test correlated negatively with serum albumin and iron concentrations and with postoperative weight loss, and positively with serum alkaline phosphatase activity. CONCLUSIONS:Bacterial overgrowth is common in the upper intestine after total gastrectomy. Pouch reconstruction does not delay the transit of liquids. Bacterial overgrowth may be one of the main aetiologic factors in postgastrectomy malnutrition.

journal_name

Scand J Gastroenterol

authors

Iivonen MK,Ahola TO,Matikainen MJ

doi

10.1080/00365529850166220

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

63-70

issue

1

eissn

0036-5521

issn

1502-7708

journal_volume

33

pub_type

临床试验,杂志文章,随机对照试验
  • Reduction of gastric acid secretion by 10 mg and 30 mg omeprazole once daily.

    abstract::The reduction in gastric acid secretion by 10 mg and 30 mg omeprazole was studied in 12 patients with ulcer disease in a randomized, double-blind, two-way balanced crossover study. A standardized pentagastrin test was performed before the study and 24 h after each treatment period of 6 days. Treatment was followed by ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00365528509089282

    authors: Nielsen AM,Stenderup J,Wandall JH,Bonnevie O

    更新日期:1985-12-01 00:00:00

  • Changes in inflammatory bowel disease subtype during follow-up and over time in 44,302 patients.

    abstract:AIM:To investigate inflammatory bowel disease (IBD) register-based subtype classifications over a patient's disease course and over time. METHODS:We examined International Classification of Diseases coding in patients with ≥2 IBD diagnostic listings in the National Patient Register 2002-2014 (n = 44,302). RESULTS:18%...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2018.1564361

    authors: Everhov ÅH,Sachs MC,Malmborg P,Nordenvall C,Myrelid P,Khalili H,Elmberg M,Ekbom A,Askling J,Jakobsson G,Halfvarson J,Ludvigsson JF,Olén O

    更新日期:2019-01-01 00:00:00

  • Hydrolysis of phosphatidylinositol by human pancreatic phospholipase A2.

    abstract::Pure human pancreatic phospholipase A2 efficiently hydrolyzed the 2-ester bond of 14C-2-linoleoyl and 14C-2-arachidonyl phosphatidylinositol (PI). The rate of hydrolysis varied markedly with the bile salt (sodium taurocholate to sodium taurodeoxycholate, 3:4 mol/mol) concentration, the hydrolysis being decreased with ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529009107934

    authors: Barros H,Sternby B,Nilsson A

    更新日期:1990-02-01 00:00:00

  • Transjugular intrahepatic portosystemic shunt with the Strecker stent for control of refractory acute and chronic variceal bleeding.

    abstract:BACKGROUND:We wanted to assess prospectively the safety, efficacy, and applicability of transjugular intrahepatic portosystemic shunt (TIPS) with the Strecker stent, focusing mainly on clinical and hemodynamic medium- and long-term follow-up. METHODS:Fifty-two patients reached an indication to perform a TIPS, in an em...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529609004880

    authors: Canizares RB,Rodriguez-Laiz JM,Martin MC,Belda AE,Alonso FC,Roldan FP,Castro LS,Arregui EC,Ricote GC

    更新日期:1996-03-01 00:00:00

  • Effect of the histamine H2-receptor antagonist, cimetidine, on gastric secretion and serum gastrin during insulin infusion in Man.

    abstract::Cimetidine infusion (100 mg h-1) reduced the acid secretory response to insulin infusion (0.03 units Kg-1h-1) when compared to paired control tests in 6 healthy volunteers. There was no significant difference between cimetidine and control tests in terms of pepsin output or serum gastrin concentrations. Cimetidine als...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Carter DC,Forrest JA,Logan RA,Ansell I,Lidgard G,Heading RC,Shearman DJ

    更新日期:1976-01-01 00:00:00

  • Relevance of abdominal gas analysis and transit study after colorectal cancer surgery.

    abstract:BACKGROUND:Colon gas volume analysis using abdominal radiographs is an objective and reproducible method for evaluating functional bowel disorders. The aim of this study was to clarify the relevance of colon gas distribution and transit time in rectosigmoid cancer patients after surgery. METHODS:Segmental colon gas vo...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520310000898

    authors: Seike K,Koda K,Oda K,Kondo E,Ishizuka M,Miyazaki M

    更新日期:2003-04-01 00:00:00

  • Endoscopic management of foreign bodies in the upper gastrointestinal tract: a retrospective study of 1294 cases.

    abstract:OBJECTIVE:To report our endoscopic outcomes and explore the effects of duration of impaction and anesthetic methods on the endoscopic removal of foreign bodies in the upper gastrointestinal tract. METHODS:All consecutive patients with suspected foreign body (FB) ingestion between January 2013 and June 2016 were enroll...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1350284

    authors: Geng C,Li X,Luo R,Cai L,Lei X,Wang C

    更新日期:2017-11-01 00:00:00

  • Endoscopic manometry of the sphincter of Oddi and the pancreatic and biliary ducts in patients with chronic pancreatitis.

    abstract::Sphincter of Oddi activity and the common bile duct (CBD) and pancreatic duct (PD) pressures were measured by means of endoscopic manometry in 15 patients (11 men and 4 women aged 18-77 (median, 40) years) with various degrees of chronic pancreatitis. Eleven of the 15 patients studied had an abnormal manometric patter...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529409090461

    authors: Vestergaard H,Kruse A,Rokkjaer M,Frøbert O,Thommesen P,Funch-Jensen P

    更新日期:1994-02-01 00:00:00

  • Acetazolamide interferes with the protective effect of prostaglandin E2 in the rat gastric mucosa.

    abstract::Oral prostaglandin E2 protected the gastric mucosa against the damage induced by intraperitoneal indomethacin in the rat. Blocking of the gastric alkaline secretion by subcutaneous acetazolamide potentiated the ulcerogenic action of indomethacin and reduced or abolished the protective effect of a submaximal dose prost...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528109181985

    authors: Kollberg B,Aly A,Rubio C,Johansson C

    更新日期:1981-04-01 00:00:00

  • Evidence for predominant involvement of the B-cell system in the inflammatory process in Crohn's disease.

    abstract::The cellular infiltrate in the walls of resected ileum and colon specimens obtained from patients with Crohn's disease was analysed. Mononuclear cells in tissue sections were characterized by the use of surface membrane markers and immuno-histochemical and enzyme histochemical techniques. It was found that: [1] B cell...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365527909179842

    authors: Meijer CJ,Bosman FT,Lindeman J

    更新日期:1979-01-01 00:00:00

  • Delayed mid-ileal perforation secondary to acute-on-chronic ischaemia after a diagnostic colonoscopy.

    abstract::Perforation occurring at a remote site of the bowel after diagnostic colonoscopy is rare. A 61-year-old man presenting with bloody diarrhoea underwent colonoscopy. A dynamic ileus developed in less than 1 day, and mid-ileal perforation occurred 7 days after the procedure. It is suggested that high air pressure during ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655298750027065

    authors: Chau TN,Ng C,Lau LK,Lai ST,Yuen H

    更新日期:1998-09-01 00:00:00

  • Bile viscosity in patients with biliary drainage. Effect of co-trimoxazole and N-acetylcysteine and role in stent clogging.

    abstract:BACKGROUND:The main disadvantage of endoscopic insertion of an endoprosthesis is the tendency of the stent to clog after a few months. In this study we determined the role of bile viscosity in stent clogging. METHODS:Sixty patients were stented with 10 Fr 11-cm stents. The stents were electively removed after 2 months...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00365529409092506

    authors: Coene PP,Groen AK,Davids PH,Hardeman M,Tytgat GN,Huibregtse K

    更新日期:1994-08-01 00:00:00

  • Detection of naproxen-induced intestinal permeability change may be facilitated by adding a standardized meal but not by forming marker ratios.

    abstract:BACKGROUND:We recently compared the intestinal permeability markers polysucrose (PS) 15,000, 51Cr-ethylenediaminetetraacetic acid (EDTA), and 14C-mannitol in healthy humans. We have now studied the ability of these markers to show non-steroidal anti-inflammatory drug (NSAID)-induced intestinal damage, with special rega...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529609036908

    authors: Oman H,Henriksson AE,Johansson SG,Blomquist L

    更新日期:1996-12-01 00:00:00

  • Availability of energy substrates during liver regeneration in malnourished rats.

    abstract::A retarded liver regeneration rate during malnutrition has previously been reported. To explore the mechanisms, some energy substrates were studied during liver regeneration and malnutrition. Forty-one rats were allocated to one of three groups (G): GI were normally nourished rats, which were partially hepatectomized;...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529108998607

    authors: Skullman S,Ihse I,Larsson J

    更新日期:1991-11-01 00:00:00

  • Carcinoma of the pancreas and papilla of Vater: presenting symptoms, signs, and diagnosis related to stage and tumour site. A prospective multicentre trial in 472 patients. Norwegian Pancreatic Cancer Trial.

    abstract::During the period 1984-87, 472 patients with histologically or cytologically verified carcinoma of the pancreas (n = 442) or the papilla of Vater (n = 30) were accrued. Diagnostic investigations were performed in accordance with the ordinary routines of 38 Norwegian hospitals. Jaundice at presentation, found in 47% of...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.3109/00365529209000081

    authors: Bakkevold KE,Arnesjø B,Kambestad B

    更新日期:1992-04-01 00:00:00

  • Evaluation of the secretin-cholecystokinin test for chronic pancreatitis by discriminant analysis.

    abstract::Discriminant analysis was used to interpret the results of the secretin-cholecystokinin (CCK) test in the diagnosis of chronic pancreatitis. An allocation rule based on the use of two test variables--mean chymotrypsin concentration and peak bicarbonate output--was constructed to distinguish between 63 patients with ch...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528609034618

    authors: Heij HA,Obertop H,Schmitz PI,van Blankenstein M,Westbroek DL

    更新日期:1986-01-01 00:00:00

  • Coeliac disease diagnosed by means of duodenoscopy and endoscopic duodenal biopsy.

    abstract::Nineteen patients with suspected coeliac disease were examined by duodenoscopy and biopsy. In all patients a histopathology consistent with coeliac disease was demonstrated in endoscopic biopsies of the duodenal mucosa. On close-up view villous atrophy was seen in vivo. Fourteen patients were re-examined on a gluten-f...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365527709181349

    authors: Gillberg R,Ahrén C

    更新日期:1977-01-01 00:00:00

  • Clinicopathological characteristics of biliary neuroendocrine neoplasms: a multicenter study.

    abstract:OBJECTIVES:This study assessed the clinicopathological features, therapeutic approaches, and prognosis of patients with biliary neuroendocrine neoplasm (NENs). MATERIALS AND METHODS:Multicenter retrospective study of patients with biliary tract NENs in the gallbladder, the extrahepatic bile duct, or the ampulla of Vat...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.1080/00365521.2016.1261938

    authors: Lee KJ,Cho JH,Lee SH,Lee KH,Park BK,Lee JK,Woo SM,Ryu JK,Lee JK,Kim YS,Kim JW,Lee WJ

    更新日期:2017-04-01 00:00:00

  • Development and feasibility of a telemonitoring tool with full integration in the electronic medical record: a proof of concept study for patients with inflammatory bowel disease in remission on biological therapy.

    abstract::Objectives: Telemonitoring can be implemented to enhance disease monitoring and ultimately reduce the number of outpatient visits and associated costs. We developed an in house IBD mobile app and established a proof of concept study to demonstrate the effectiveness and accuracy of the telemonitoring tool for monitorin...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2020.1735506

    authors: Coenen S,Nijns E,Weyts E,Geens P,Van den Bosch B,Vermeire S,Ferrante M,Vanhaecht K,Van Assche G

    更新日期:2020-03-01 00:00:00

  • Parental occupations and risk for Crohn's disease in children.

    abstract:BACKGROUND AND OBJECTIVES:Lacunae exist on the identity of specific environmental risk factors that associate with Crohn's disease (CD). We hypothesized that indirect exposures acquired via the parents' occupation may confer susceptibility. METHODS:A case-control study based on children diagnosed with CD (prior to age...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1339826

    authors: Eslahpazir J,Kumar R,Lalavi A,Amre DK

    更新日期:2017-10-01 00:00:00

  • Pain produced by electric stimulation of the rectum in patients with irritable bowel syndrome: further evidence of visceral hyperalgesia.

    abstract:BACKGROUND:Visceral hyperalgesia is most likely a phenomenon of substantial clinical importance and may also play a role in the pathophysiology of the irritable bowel syndrome (IBS). We investigated the manifestation of visceral hyperalgesia in IBS patients by nociceptive electric stimulation of the rectosigmoid juncti...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655299750025101

    authors: Rössel P,Drewes AM,Petersen P,Nielsen J,Arendt-Nielsen L

    更新日期:1999-10-01 00:00:00

  • Cyclic AMP and gastric secretion in man. An in vivo study in healthy volunteers, duodenal ulcer patients, and pernicious anaemia patients.

    abstract::The metabolism of cyclic AMP and HCl secretion has been studied in eight healthy volunteers, in eight duodenal ulcer (DU) patients, and in four pernicious anaemia patients. Pentagastrin showed a tendency to increase adenylate cyclase and cyclic nucleotide phosphodiesterase activities in the fundal mucosa and caused a ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528809090165

    authors: Varis K,Raij K,Härkönen M,Miettinen TA

    更新日期:1988-11-01 00:00:00

  • Effect of selective and non-selective antimuscarinics on rectosigmoid motility and gastrointestinal transit.

    abstract::In 12 healthy volunteers, a rectosigmoid motility index (RSMI) was measured when either placebo, 0.5 mg atropine, or 5 mg pirenzepine was given intravenously as a single dose, double-blind, in random order after a control period of 30 min. Compared with the control period, atropine gave a significant decrease of the R...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00365528509088879

    authors: Jaup BH,Abrahamsson H,Stockbruegger RW,Rosengren K,Dotevall G

    更新日期:1985-11-01 00:00:00

  • Microvasculature of the human pancreas. A microangiographic study.

    abstract::The microvasculature of six human pancreases was studied immediately after resection. Three of the pancreases were histologically normal, two were fibrotic, and one was inflamed. Immediately after resection a 10% Micropaque (Nicholas) solution was infused into the lienal artery for 1 h, and the tissue was studied by m...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365527909181938

    authors: Kivisaari L

    更新日期:1979-01-01 00:00:00

  • Assessing guideline adherence in patients with non-variceal upper gastrointestinal bleeding receiving antiplatelet and anticoagulant therapy.

    abstract::Background & aims: Non-variceal upper gastrointestinal bleeding (NVUGIB) occurs frequently and is associated with a significant morbidity and mortality, especially in patients receiving antiplatelet or anticoagulant therapy (APT and ACT, respectively). We aimed to evaluate adherence to guideline recommendations publis...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2019.1688384

    authors: Vogt C,Allo G,Buerger M,Kasper P,Chon SH,Gillessen J,Goeser T,Schramm C

    更新日期:2019-11-01 00:00:00

  • Mucosal cell proliferation in patients with hyperplastic colorectal polyps.

    abstract:BACKGROUND:Morphologic, histochemical, and cytoproliferative characteristics differentiate hyperplastic polyps from adenomas. Even so, these polyps are indicators of populations with a high colorectal cancer risk. Since changes in mucosal cell proliferation are highly predictive biomarkers of the adenomacarcinoma seque...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529509093288

    authors: Risio M,Arrigoni A,Pennazio M,Agostinucci A,Spandre M,Rossini FP

    更新日期:1995-04-01 00:00:00

  • Impairment of vitamin D metabolism and bone mineral content after intestinal bypass for obesity. A longitudinal study.

    abstract::Ten obese subjects who had undergone intestinal bypass operation (end-to-side jejunoileostomy) were studied longitudinally with respect to vitamin D and other indices of calcium metabolism. Investigations were carried out before operation (t0) and after 6 months (t1), 12 months (t2), and a mean of 54 months (range, 49...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Rickers H,Christiansen C,Balslev I,Rødbro P

    更新日期:1984-03-01 00:00:00

  • Primary sclerosing cholangitis and the microbiota: current knowledge and perspectives on etiopathogenesis and emerging therapies.

    abstract::Primary sclerosing cholangitis (PSC) is a chronic, fibroinflammatory, cholestatic liver disease of unknown etiopathogenesis. PSC generally progresses to liver cirrhosis, is a major risk factor for hepatobiliary and colonic neoplasia, and confers a median survival to death or liver transplantation of only 12 years. Alt...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3109/00365521.2014.913189

    authors: Tabibian JH,O'Hara SP,Lindor KD

    更新日期:2014-08-01 00:00:00

  • Enzyme activities in the gastric mucosa in duodenal ulcer patients.

    abstract::In a series of 45 consecutive duodenal ulcer patients (DU) the activities of 10 marker enzymes from the brush border, basolateral membrane, mitochondria, and lysosomes were determined by analysis of homogenized material taken with biopsy forceps through an endoscope from the antral and body part of the stomach. They w...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529009095535

    authors: Vetvik K,Schrumpf E,Andersen KJ,Børkje B,Odegaard S,Skagen DW,Halvorsen OJ

    更新日期:1990-06-01 00:00:00

  • HLA-DR expression and disease activity in ulcerative colitis.

    abstract::In 12 patients with active ulcerative colitis (UC) the rectal epithelial cells were analyzed for HLA-DR antigens by an immunohistochemical technique. The clinical, rectoscopic, and histologic stages were also determined. The investigations were carried out at the beginning of the study and 2 weeks and 3 months later. ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528609003088

    authors: Poulsen LO,Elling P,Sørensen FB,Høedt-Rasmussen K

    更新日期:1986-04-01 00:00:00