Abstract:
OBJECTIVES:Apathy is a prevalent neuropsychiatric manifestation in individuals with Alzheimer's disease (AD) that is associated with decreased social functioning and increased caregiver burden. Olfactory deficits are also commonly observed in AD, and prior work has indicated a link between increased apathy and olfactory dysfunction in individuals with Parkinson's disease. Here, we examined odor identification performance in patients with probable AD (n = 172), individuals with mild cognitive impairment (MCI; n = 112), and neurologically and psychiatrically healthy older adults (n = 132) and its relation to apathy, depression, and overall psychopathology. METHOD:Participants were administered the Sniffin' Sticks odor identification test and measures assessing severity of apathy, depression, and overall neuropsychiatric symptomatology. RESULTS:Consistent with previous research, AD and MCI patients were significantly worse at identifying odors than healthy older adults. Additionally, a sex by diagnosis interaction was observed. AD patients had significantly higher levels of apathy relative to MCI and control participants. Of note, across the entire sample odor identification deficits were correlated with level of apathy at the level of p < 0.01, but not with depression or neuropsychiatric symptom severity, when controlling for Mini-Mental State Examination (MMSE) score. CONCLUSION:Collectively, these data suggest that olfactory disturbance and apathy in AD may result from the progression of disease pathology in shared neural substrates.
journal_name
Aging Ment Healthjournal_title
Aging & mental healthauthors
Seligman SC,Kamath V,Giovannetti T,Arnold SE,Moberg PJdoi
10.1080/13607863.2013.768208subject
Has Abstractpub_date
2013-01-01 00:00:00pages
564-70issue
5eissn
1360-7863issn
1364-6915journal_volume
17pub_type
杂志文章abstract:OBJECTIVES:To identify caregiver profiles of persons with mild to moderate dementia and to investigate differences between identified caregiver profiles, using baseline data of the international prospective cohort study Actifcare. METHODS:A latent class analysis was used to discover different caregiver profiles based ...
journal_title:Aging & mental health
pub_type: 杂志文章,多中心研究
doi:10.1080/13607863.2016.1255716
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:Evidence points to an association between social and leisure activity (SLA) engagement and cognitive outcomes, but the mechanisms underlying this link remain unknown. We aimed to investigate three potential mechanisms: Vascular function, Perceived Stress, and Cognitive Reserve. METHODS:With data from 8163 ad...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2016.1233935
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:The authors set out to systematically review the research literature in order to identify the anxiety measures most commonly used in the assessment of older adults. Once identified, the literature was reviewed to determine the extent to which these instruments had age-relevant norms and psychometric data sup...
journal_title:Aging & mental health
pub_type: 杂志文章,评审
doi:10.1080/13607863.2011.602960
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:The research largely aimed at exploring the impact of marital status, cognitive efficiency, gender, physical health and sociocultural context on self-rated emotional competence, depression, memory and cognitive measures. METHOD:Ninety-four healthy adults aged 75-99 were recruited in the Sardinian province o...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2013.866635
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVES:This study examines: (1) the effect of widowed persons' frequency of contact with friends and relatives on their depressive and grief symptoms six months following spousal loss and (2) the extent to which the effects of social contact are contingent upon the degree of emotional support received from these re...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2010.519325
更新日期:2011-04-01 00:00:00
abstract::Objectives: The aim of the current study was to assess the associations between dynapenia and the onset and persistence of depression and anxiety among older adults.Methods: This prospective cohort study enrolled community-living older adults (N = 5271; 51.1% females) aged ≥ 50 years (mean age = 63.2, standard deviati...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2019.1699021
更新日期:2019-12-12 00:00:00
abstract::Objectives: Impaired cognition and pre-frailty are associated with poor health outcomes. However, research has not examined the combined impact of cognitive impairment and pre-frailty on future frailty and mortality among older Mexican Americans. Methods: Data for this analysis came from the 2006-2007 and 2010-2011 wa...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2018.1493719
更新日期:2019-10-01 00:00:00
abstract::Background and objectives: People with dementia occupy around one quarter of general hospital beds, with concerns consistently raised about care quality. Improving workforce knowledge, skills and attitudes is a mechanism for addressing this. However little is known about effective ways of training healthcare staff abo...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2018.1531382
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:The aim of the analysis is to assess the impact of privately employed migrant care workers (MCWs) on the burden of Italian family members who care for a disabled older person. METHODS:EUROFAMCARE is a one-year prospective survey carried out to provide evidence on the availability and use of support services ...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2013.765830
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:The current research explores how family caregivers (1) make sense of caregiving and (2) cope with their circumstance. METHOD:We analysed semistructured interviews of 13 caregivers of people with either stroke (n = 5) or dementia (n = 8) and used photographs that caregivers took exemplifying their caregivin...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2013.860425
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was to investigate the association between trait gratitude and loneliness in a Dutch population sample of adults over 40 years. In addition, the mediating role of psychological flexibility and engaged living between trait gratitude and loneliness was assessed. METHOD:A total sam...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2019.1673309
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVES:Although generalized anxiety disorder (GAD) is one of the most prevalent anxiety disorders in older adults, very little is known about the neurobiology of worry, the hallmark symptom of GAD in adults over the age of 60. This study investigated the neurobiology and neural circuitry of worry in older GAD patie...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2015.1109058
更新日期:2017-04-01 00:00:00
abstract::Objectives: A considerable body of work addresses prevalence and treatment options for depression in older adults. However, less is known about their capacity to self-manage their depression. Effective self-management of depression has the potential to improve individuals' quality of life through information, empowerm...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2018.1562538
更新日期:2020-06-01 00:00:00
abstract::Cognitive aging research suggests that environmental support can minimize memory failures in older adults. Similarly, designers of dwellings for frail and dementing older populations try to provide prosthetic environments to support greater independence. We review some of these research issues and design practices fro...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Few studies have investigated the bidirectional association between depression and multimorbidity from a longitudinal perspective. We aimed to explore the bidirectional relationship between depression and multimorbidity in a middle-aged and elderly Chinese population. METHODS:Participants aged 45 years and ...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2021.1877609
更新日期:2021-01-29 00:00:00
abstract::This paper reports findings from the carer component of the Gwynedd Dementia Study. It is based on carer interviews, using quantitative and qualitative data. It confirms earlier findings that carers for people with dementia are typically female and older than other carers, although it notes that caring husbands are am...
journal_title:Aging & mental health
pub_type: 杂志文章,多中心研究
doi:10.1080/13607860120101040
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVES:Little is known about composite patterns of productive engagement among older people. Related, the implication of these patterns for well-being remains unclear. The present study addresses these gaps. METHODS:The analytical sample comprised 2037 community-dwelling Singaporeans aged 60 years and above. We in...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2019.1686458
更新日期:2021-02-01 00:00:00
abstract::Objectives: Mentally stimulating leisure activities and cognitive interventions are associated with delayed cognitive decline, although evidence has not been unequivocal, possibly due to differential contribution of the two types of activities. This study aimed to examine the respective contributions of mentally activ...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2019.1636204
更新日期:2020-11-01 00:00:00
abstract::The current emphasis on early detection and disclosure of a diagnosis of dementia highlights the need to examine couples' shared constructions of, and responses to, the diagnosis, and to explore the appraisals that couples make about the illness at an early stage. While the experiences of carers and of people with dem...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607860500114555
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVES:The primary objective of this work is to report the observed changes in psychological well-being in a sample of long-term medically hospitalized patients, after attending a cognitive stimulation program. The secondary aim is to determine if the observed changes were related to previous cognitive level. METH...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2015.1099033
更新日期:2017-01-01 00:00:00
abstract::Objectives: The purpose of this study was to validate the Chinese version of the Brief Aging Perception Questionnaire (B-APQ) for older persons with chronic disease living in Taiwan.Methods: This study recruited older patients with chronic diseases from outpatient departments of a medical center in southern Taiwan. Fi...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2020.1734914
更新日期:2020-03-05 00:00:00
abstract::During World War Two 1.9 million people were evacuated from British cities where the risk of bombing was perceived to be highest. 1.5 million of these were children who, often unaccompanied, were sent to live with strangers. Two hundred and forty-five people who were evacuated as children were compared with 96 of simi...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607860600844473
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:The intent of this exploratory qualitative study was to examine African American Baptist clergy's pastoral care to older congregants with mental disorders. Critical Race Theory was the guiding framework in this study. METHOD:A purposive sample of 18 African American clergy participated in one-on-one intervie...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2017.1364343
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:Dementia is one of the leading causes of dependence in the elderly. This study was conducted to estimate diagnostic performance of dementia screening tests including Mini-Mental State Examination (MMSE), Mini-Cog, Clock Drawing Test (CDT) and Ascertain Dementia 8 questionnaire (AD8) by Bayesian models. METHO...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2017.1320701
更新日期:2018-08-01 00:00:00
abstract:UNLABELLED:Hoarding disorder (HD) in late life is associated with increased risk for fire, falling, poor sanitary conditions, disability, and health risks. However, research on the health status of individuals with HD is limited. Hoarding symptoms and the resulting clutter may exacerbate health conditions and lead to i...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2013.814105
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVES:In the UK and elsewhere, specialist community mental health teams (CMHTs) are central to the provision of comprehensive services for older people with mental ill health. Recent guidance documents suggest a core set of attributes that such teams should encompass. This article reports on a systematic literatur...
journal_title:Aging & mental health
pub_type: 杂志文章,评审
doi:10.1080/13607863.2011.651431
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:To investigate changes of cognitive performances in female elderly patients with osteoporosis and to determine whether any impairments can be attributed to dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. METHODS:This cross-sectional study included 277 postmenopausal women, who were divided i...
journal_title:Aging & mental health
pub_type: 杂志文章,多中心研究
doi:10.1080/13607863.2015.1033680
更新日期:2016-01-01 00:00:00
abstract::Objectives: Explorations of relationships between loneliness and depression have focused on loneliness as a uni-dimensional construct. We hypothesised that reciprocal relationships may exist between depressive symptomatology and social and emotional subtypes of loneliness.Methods: Using data from 373 adults aged over ...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2018.1517728
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:Older adults who have experienced traumatic events earlier in life may be especially vulnerable to additional challenges associated with aging. In a cross-sectional study of older females, the present study examines whether a history of rape is associated with current psychological and health problems. METH...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2014.884538
更新日期:2014-01-01 00:00:00
abstract::Objectives: The study used data from the Canadian Longitudinal Study on Aging to investigate the relationships among social support (measured as affectionate support, emotional/informational support, positive social interaction, tangible support), social participation and depression in caregivers and non-caregivers.Me...
journal_title:Aging & mental health
pub_type: 杂志文章
doi:10.1080/13607863.2018.1544223
更新日期:2020-05-01 00:00:00