Prevalence and genotype of hepatitis C virus infection in pregnant women and blood donors in Ghana.

abstract：:Arboviruses are maintained and transmitted through an alternating biological cycle in arthropods and vertebrates, with largely incidental disease in humans and animals. As such, they provide excellent examples of One Health, as their health impact is inextricably linked to their vertebrate hosts, their arthropod vecto...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mackenzie JS,Lindsay MDA,Smith DW,Imrie A

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Manual white blood cell (WBC) differential counts as a predictor for neonatal sepsis development in a low-resource setting have not been thoroughly evaluated. We hypothesized that manual differentiation (specifically immature:total [I:T] neutrophil ratios) would be feasible and useful as an adjunct to predic...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Golding CN,Schaltz-Buchholzer F,Sanca L,Clipet-Jensen C,Benn CS,Au N,Chipperfield K,Kollmann TR,Amenyogbe NA

更新日期：2020-08-01 00:00:00

abstract：:Among infectious diseases, tuberculosis is the leading cause of death, killing around 3 million people each year. Most cases occur in young adults but it is also a major cause of illness and death in children. The problem has been exacerbated in recent years by the HIV pandemic and by the emergence of multidrug resist...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Zumla A,Squire SB,Chintu C,Grange JM

更新日期：1999-03-01 00:00:00

abstract：:Although intestinal helminth and protozoan infections are prevalent throughout the world, their impact is poorly known. Nevertheless, the morbidity and mortality that occur have stimulated research into host resistance and pathogenesis. Unfortunately, despite an increasing knowledge base, the actual effector molecules...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Befus D

更新日期：1986-01-01 00:00:00

abstract：:Pneumocystis carinii occurs in 60-65% of cases of acquired immunodeficiency syndrome (AIDS) in Europe and North America. Its prevalence in Africa is unknown, however, due to a lack of suitable investigative techniques. Initial studies suggest that this parasitic complication may be lower in Africa. An investigation of...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Carme B,Mboussa J,Andzin M,Mbouni E,Mpele P,Datry A

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Ultrasound utilization studies in the developing world are important to support appropriate use. METHODS:A prospective, cross-sectional study in the medical wards at Queen Elizabeth Central Hospital, Blantyre, Malawi, was performed which aimed to assess referrals, reports and usefulness of scans to develop ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Brindle HE,Allain TJ,Kampondeni S,Kayange N,Faragher B,Bates I,Joekes E

更新日期：2013-07-01 00:00:00

abstract：:Preserved sera from patients with various forms of leishmaniasis, acute and chronic Chagas's disease and from normal individuals were examined for the presence of IgG and IgA antibodies by the IFA test. The leishmanial antigen used in the IFA test was prepared from a hamster infected with the PH8 strain of Leishmania ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Shaw JJ,Lainson R

更新日期：1981-01-01 00:00:00

abstract：:Roots of Pseudocedrela kotschyi are commonly used as chewing sticks in West Africa. This study examined the effects of the plant extract on the in-vitro growth of Plasmodium falciparum. Ring-stage synchronised cultures of the malaria parasite were exposed to 30 and 60 microg/ml of P. kotschyi extract for 51 h. Aliquot...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kassim OO,Loyevsky M,Amonoo H,Lashley L,Ako-Nai KA,Gordeuk VR

更新日期：2009-07-01 00:00:00

abstract：:Lymphatic filariasis (LF) caused by Wuchereria bancrofti is widely prevalent in tropical and subtropical countries. Night blood film examination is most commonly used for diagnosis of filariasis but is cumbersome and labour intensive. In order to develop an indirect ELISA-based immunodiagnostic test, the importance of...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Singh A,Kamal S,Rathaur S

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Mumbai is a hot spot for drug-resistant TB, and private practitioners trained in AYUSH systems (Ayurveda, yoga, Unani, Siddha and homeopathy) are major healthcare providers. It is important to understand how AYUSH practitioners manage patients with TB or presumptive TB. METHODS:We conducted semi-structured ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： McDowell A,Pai M

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Large numbers of tuberculosis (TB) patients seek care from private for-profit providers. This study aimed to assess and compare TB control activities in the private for-profit and public sectors in Kenya between 2013 and 2017. METHODS:We conducted a retrospective cross-sectional study using routinely collec...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mailu EW,Owiti P,Ade S,Harries AD,Manzi M,Omesa E,Kiende P,Macharia S,Mbithi I,Kamene M

更新日期：2019-12-01 00:00:00

abstract：:Leprosy type 1 reactions (T1R) are immune-mediated events with inflammation of peripheral nerves and skin. We report the clinical outcomes of a closely monitored open prospective trial in which eight Nepali and 33 Ethiopian patients with T1Rs were treated with an Indian generic formulation of ciclosporin (Cn; 5-7.5 mg...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Marlowe SN,Leekassa R,Bizuneh E,Knuutilla J,Ale P,Bhattarai B,Sigdel H,Anderson A,Nicholls PG,Johnston A,Holt D,Lockwood DN

更新日期：2007-10-01 00:00:00

abstract：:Antimicrobial resistance is threatening to undermine many of the health care improvements achieved in the tropics in the past 2 decades. While only limited data are available, there is evidence from most tropical areas of the spread of resistant bacterial strains in diseases from typhoid and bacillary dysentery to tub...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Shears P

更新日期：2001-03-01 00:00:00

abstract：:Countries around the world are facing an enormous challenge due to the COVID-19 pandemic. The pressure that the pandemic inflicts on health systems could certainly impact on the care, control, and elimination of neglected tropical diseases (NTDs). From mid-January 2020, Ethiopia started to prepare for the prevention a...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Abdela SG,van Griensven J,Seife F,Enbiale W

更新日期：2020-10-05 00:00:00

abstract：:The COVID-19 pandemic has exposed health system weaknesses of economically wealthy countries with advanced technologies. COVID-19 is now moving fast across Africa where small outbreaks have been reported so far. There is a concern that with the winter transmission will grow rapidly. Despite efforts of African Governme...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Vilakati PN,Villa S,Alagna R,Khumalo B,Tshuma S,Quaresima V,Nieman NR,Cirillo DM,Raviglione MC

更新日期：2020-10-05 00:00:00

abstract：:A range of animal models of Burkholderia pseudomallei infection have been reported, and the host species differ widely both in their susceptibility to infection and in the pathogenesis of disease. In mice, and depending on the route of infection, dose, and mouse strain, the disease can range from a chronic, and in som...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Titball RW,Russell P,Cuccui J,Easton A,Haque A,Atkins T,Sarkar-Tyson M,Harley V,Wren B,Bancroft GJ

更新日期：2008-12-01 00:00:00

abstract：:The relationships between intestinal parasitism and excreta disposal technologies in Gaborone (Botswana), Ndola (Zambia) and Kumasi (Ghana) were investigated. Parasitic prevalence and intensity rates amongst groups of urban residents having similar socio-economic status and housing, but different excreta disposal tech...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Feachem RG,Guy MW,Harrison S,Iwugo KO,Marshall T,Mbere N,Muller R,Wright AM

更新日期：1983-01-01 00:00:00

abstract：:In a longitudinal study to determine the effect of annual community-based treatment of ocular onchocerciasis with ivermectin, the population living in the 3 most affected villages in the holo-endemic onchocerciasis focus of Asubende in Ghana were re-examined 16 and 24 months after initiating treatment. Ocular microfil...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Dadzie KY,Remme J,De Sole G

更新日期：1991-03-01 00:00:00

abstract：:A sensitive high-performance liquid chromatographic method has been developed for the separation and quantitative estimation of melaminophenyl arsenical drugs used in the treatment of human and veterinary trypanosomiases. Five clinically relevant compounds (melarsoprol, melarsonyl potassium, cymelarsan, melarsen oxide...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Berger BJ,Fairlamb AH

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Characterization of the epidemiology of Escherichia coli bloodstream infection (BSI) in sub-Saharan Africa is lacking. We studied patients with E. coli BSI in northern Tanzania to describe host risk factors for infection and to describe the antimicrobial susceptibility of isolates. METHODS:Within 24 h of ad...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Madut DB,Rubach MP,Kalengo N,Carugati M,Maze MJ,Morrissey AB,Mmbaga BT,Lwezaula BF,Kilonzo KG,Maro VP,Crump JA

更新日期：2020-05-07 00:00:00

abstract：:Freeze-dried and freshly cultured isolates of Plasmodium falciparum from different countries have been examined for variation in six enzymes, GPI, PGD, LDH, GDH, ADA and PEPE, using starch gel electrophoresis. Variant forms of each enzyme occur. For most enzymes, similar forms occur in isolates from different parts of...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Sanderson A,Walliker D,Molez JF

更新日期：1981-01-01 00:00:00

abstract：:Microsporidiosis in AIDS patients has emerged as an important cause of morbidity, but diagnosis requires special stains, equipment and expertise. Here we describe a modification to an existing staining technique to allow more rapid preparation, without additional equipment, facilitating research in the tropics into th...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Sianongo S,McDonald V,Kelly P

更新日期：2001-11-01 00:00:00

abstract：:The incidence and progression of coagulation abnormalities were studied in 52 patients with acute falciparum malaria. The patients were prospectively divided into 3 groups; severe (parasitaemia greater than or equal to 5% or vital organ dysfunction), 12 patients; moderate (parasitaemia 1%- less than 5% without complic...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Pukrittayakamee S,White NJ,Clemens R,Chittamas S,Karges HE,Desakorn V,Looareesuwan S,Bunnag D

更新日期：1989-11-01 00:00:00

abstract：Background:HIV-associated TB is a serious public health problem in Myanmar. Study objectives were to describe national scale-up of collaborative activities to reduce the double burden of TB and HIV from 2005 to 2016 and to describe TB treatment outcomes of individuals registered with HIV-associated TB in 2015 in the Ma...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Theingi P,Harries AD,Wai KT,Shewade HD,Saw S,Win T,Thein S,Kyi MS,Nyunt Oo H,Aung ST

更新日期：2017-09-01 00:00:00

abstract：:Twenty Kenyan patients with visceral leishmaniasis were evaluated for the presence of Leishmania donovani in their peripheral blood. Smears, cultures and hamster inoculations detected parasitaemia in 11, 10 and six patients, respectively, and at least one method detected parasitaemia in 15 patients (75%). The likeliho...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Chulay JD,Adoyo MA,Githure JI

更新日期：1985-01-01 00:00:00

abstract：:The objective of this study was to investigate complement activation in uncomplicated, early phases of human malaria. Fifteen healthy volunteers were experimentally infected with Plasmodium falciparum malaria. Parasitemia and complement activation products were assessed. During blood stage parasitemia, volunteers show...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Roestenberg M,McCall M,Mollnes TE,van Deuren M,Sprong T,Klasen I,Hermsen CC,Sauerwein RW,van der Ven A

更新日期：2007-07-01 00:00:00

abstract：:Antibody to Ebola virus was found in 14 (1.2%) of 1147 human sera collected in Gabon in 1981-1997. Six seropositive subjects were bled in the northeast in 1991, more than 3 years prior to recognition of the first known outbreak of Ebola haemorrhagic fever (EHF), whilst eight came from the southwest where the disease h...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Lahm SA,Kombila M,Swanepoel R,Barnes RF

更新日期：2007-01-01 00:00:00

abstract：:This paper reports the isolation and characterization of a complementary deoxyribonucleic acid clone showing sequence homology with genes coding for the eukaryotic elongation factor 1 gamma (EF-1 gamma). The clone encodes an open reading frame of 404 amino acids corresponding to a deduced molecular mass of 46.2 kDa. D...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Cañavate C,el Bali M,Montoya Y,Barker DC,Alvar J

更新日期：2002-04-01 00:00:00

abstract：:Our laboratory is characterizing Leishmania stabilates and isolates from active leishmaniasis cases. Smears and cultures from aspirates made on different dates from a single lesion on the bridge of the nose of an 18 years old Kenyan male from Nyandarua District contained Leishmania. The isolates, NLB-271 and NLB-271-I...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mebrahtu YB,Van Eys G,Guizani I,Lawyer PG,Pamba H,Koech D,Roberts C,Perkins PV,Were JB,Hendricks LD

更新日期：1993-09-01 00:00:00

abstract：:Previous studies have shown that apoptosis-like features are observed in Blastocystis spp., an intestinal protozoan parasite, when exposed to the cytotoxic drug metronidazole (MTZ). This study reports that among the four subtypes of Blastocystis spp. investigated for rate of apoptosis when treated with MTZ, subtype 3 ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Dhurga DB,Suresh KG,Tan TC,Chandramathi S

更新日期：2012-12-01 00:00:00