Abstract:
:Enteropathy-associated T-cell lymphoma (EATL) is a rare subtype of peripheral T-cell lymphomas with a poor prognosis. Autologous stem cell transplantation (ASCT) was retrospectively evaluated as a consolidation or salvage strategy for EATL. The analysis included 44 patients who received ASCT for EATL between 2000 and 2010. Thirty-one patients (70%) were in first complete or partial remission at the time of the ASCT. With a median follow-up of 46 months, relapse incidence, progression-free survival, and overall survival were 39%, 54%, and 59% at 4 years, respectively, with only one relapse occurring beyond 18 months posttransplant. There was a trend for better survival in patients transplanted in first complete or partial remission at 4 years (66% vs 36%; P = .062). ASCT is feasible in selected patients with EATL and can yield durable disease control in a significant proportion of the patients.
journal_name
Bloodjournal_title
Bloodauthors
Jantunen E,Boumendil A,Finel H,Luan JJ,Johnson P,Rambaldi A,Haynes A,Duchosal MA,Bethge W,Biron P,Carlson K,Craddock C,Rudin C,Finke J,Salles G,Kroschinsky F,Sureda A,Dreger P,Lymphoma Working Party of the EBMT.doi
10.1182/blood-2012-11-466839subject
Has Abstractpub_date
2013-03-28 00:00:00pages
2529-32issue
13eissn
0006-4971issn
1528-0020pii
blood-2012-11-466839journal_volume
121pub_type
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