Abstract:
PURPOSE:The effect of exercise on body mass is likely to be partially mediated through changes in appetite control. However, no studies have examined the effect of chronic exercise on obestatin and cholecystokinin (CCK) plasma concentrations or the sensitivity to detect differences in preload energy in obese individuals. The objective of this study was to investigate the effects of chronic exercise on 1) fasting and postprandial plasma concentrations of obestatin, CCK, leptin, and glucose insulinotropic peptide (GIP) and 2) the accuracy of energy compensation in response to covert preload manipulation. METHODS:This study used a 12-wk supervised exercise program in 22 sedentary overweight/obese individuals. Fasting/postprandial plasma concentrations of obestatin, CCK, leptin, and GIP were assessed before and after the intervention. Energy compensation at a 30-min test meal after a high-energy (607 kcal) or a low-energy (246 kcal) preload and for the rest of the day (cumulative energy intake [EI]) was also measured. RESULTS:There was a significant reduction in the plasma concentration of fasting plasma GIP and both fasting and postprandial leptin concentrations after the exercise intervention (P < 0.05 for all). No significant changes were observed for CCK or obestatin. A significant preload-exercise interaction (P = 0.011) was observed on cumulative EI and energy compensation for the same period (-87% ± 196% vs 68% ± 165%, P = 0.011). Weight loss (3.5 ± 1.4 kg, P < 0.0001) was not correlated with changes in energy compensation. CONCLUSIONS:This study suggests that exercise improves the accuracy of compensation for previous EI, independent of weight loss. Unexpectedly, and in contrast to GIP and leptin, exercise-induced weight loss had no effect on obestatin or CCK concentrations.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Martins C,Kulseng B,Rehfeld JF,King NA,Blundell JEdoi
10.1249/MSS.0b013e31827d1618subject
Has Abstractpub_date
2013-05-01 00:00:00pages
805-12issue
5eissn
0195-9131issn
1530-0315journal_volume
45pub_type
杂志文章,随机对照试验abstract::A 25-yr-old female triathlete presented with 4 d of increasing left calf pain that started 1 d after an elective termination of pregnancy during the eighth week of gestation. She had been training with running, bicycling, and swimming but did not recall any injury to the calf muscle. Deep venous thrombosis of the calf...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:Fit individuals with metabolic syndrome (MetS) have lower mortality risk compared with less fit counterparts, despite the presence of obesity as a component of the syndrome. To understand the importance of fitness in treating this condition, we examined the association of fitness and fatness with central hemody...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000916
更新日期:2016-08-01 00:00:00
abstract::We studied gastric and intestinal function by gastric intubation/intestinal perfusion in six healthy male volunteers to evaluate optimal use of a 6% glucose-electrolyte (GES) solution. Gastric volume, residual volume, emptying rate, and secretion were measured for an initial 763 +/- 19 ml gastric load of GES and at th...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199704000-00009
更新日期:1997-04-01 00:00:00
abstract::To study effort tolerance in elderly women with different physical activity backgrounds, 52 physically active (PA) and 42 sedentary control women (CO) aged 66-85 yr were assigned to perform cycle ergometer exercise to their volitional maximum. Oxygen uptake, respiratory exchange ratio (RER), heart rate, work power, an...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199801000-00024
更新日期:1998-01-01 00:00:00
abstract::The physiological mechanism of exercise-induced hyperfibrinolysis is not fully understood. It has been reported that exercise increases plasma arginine vasopressin (PAVP) and that PAVP infusion enhances blood fibrinolytic activity (FA). To characterize the fibrinolytic role of PAVP during exercise, PAVP and FA were ex...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1990-08-01 00:00:00
abstract:PURPOSE:The aim of this study was to investigate the influence of mouth rinsing a CHO-electrolyte (CHO-E) solution on 1-h running performance. A second study determined whether mouth rinsing a CHO-E solution altered the blood glucose and plasma insulin concentrations at rest. METHODS:After a 13-h fast, 10 endurance-tr...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1249/MSS.0b013e3181bac6e4
更新日期:2010-04-01 00:00:00
abstract:PURPOSE:Patellar tendon abnormality (PTA) on diagnostic imaging is part of the diagnostic criteria for patellar tendinopathy. PTA and altered landing strategies are primary risk factors that increase the likelihood of asymptomatic athletes developing patellar tendinopathy. Therefore, the aim of this study was to examin...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e318275e0f2
更新日期:2013-03-01 00:00:00
abstract::The knee joints of 81 veteran soccer players between ages 40 and 74 were examined. An analysis of and relationships between soccer practice at a top level, osteoarthritis, meniscectomy, and leg axes were evaluated. One-hundred and sixty-two knees were assessed through clinical examination and X-ray examination using a...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-198508000-00005
更新日期:1985-08-01 00:00:00
abstract:PURPOSE:Although several studies have shown that immune cells stimulated by in vitro stress are capable to produce neurotrophins, there is still no evidence whether physiological stress, such as exercise, can modulate the in vivo levels of brain-derived neurotrophic factor (BDNF) in peripheral blood mononuclear cells (...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e31825ab69b
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:To determine whether the magnitude of improvement in athletic performance and the mechanisms driving these adaptations differ in relatively weak individuals exposed to either ballistic power training or heavy strength training. METHODS:Relatively weak men (n = 24) who could perform the back squat with proficie...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0b013e3181d2013a
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:The purpose of this study was to examine the ability of the YMCA submaximal exercise test protocol using a total body recumbent stepper to predict V˙O(2peak). METHODS:Of 112 individuals initially screened, 110 individuals with low to moderate cardiovascular disease risk met the inclusion criteria for participa...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e31824f5be4
更新日期:2012-08-01 00:00:00
abstract:PURPOSE:Lateral knee osteoarthritis (OA) is common after anterior cruciate ligament reconstruction (ACLR), yet gait characteristics associated with lateral knee OA after ACLR are not well understood. This cross-sectional study aimed to compare knee, trunk, pelvis, hip, and ankle kinematics and moments between people wi...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000671
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:A 20-d 6 degrees head-down tilt bed rest project was conducted to evaluate the effect of dynamic leg press and plantar flexion resistance training on muscle size and function in human plantar flexors (PF) throughout the prolonged bed rest. METHODS:Twelve healthy men participated in this study and were divided ...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1249/01.MSS.0000058367.66796.35
更新日期:2003-04-01 00:00:00
abstract::The influence of anthropometry and body composition on running economy is unclear, with previous investigations involving small relatively homogeneous groups of runners and limited anthropometric/composition measurements. PURPOSE:To comprehensively investigate the relationships of anthropometry and body composition w...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002158
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:To date, no study has examined the synergistic effects of a nutrition and combination of aerobic and strength training (CAST) on both adiposity and metabolic parameters in overweight Latina adolescent females. The goal was to assess if a 16-wk nutrition plus CAST pilot study had stronger effects on reducing adi...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0b013e31819b6aea
更新日期:2009-07-01 00:00:00
abstract:PURPOSE:The main purpose of the present investigation was to test whether and to what extent familial/genetic factors are involved in the changes of postheparin lipoprotein lipase (deltaPH-LPL) activity and triglyceride (deltaTG) levels in response to exercise training. Additional hypotheses were also tested as to whet...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200008000-00012
更新日期:2000-08-01 00:00:00
abstract:UNLABELLED:Considerable evidence suggests regular physical activity can reduce chronic pain symptoms. The dysfunction of endogenous facilitatory and inhibitory systems has been implicated in multiple chronic pain conditions. However, few studies have investigated the relationship between levels of physical activity and...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3182a69cf1
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:To test the hypothesis that leg blood flow and leg O2 extraction during peak exercise are reduced with age in healthy normally active women. METHODS:Thirteen younger (20-27 yr) and 12 older (60-71 yr) nonendurance trained women performed graded upright leg cycling to maximum exertion (VO2peak), while leg blood...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000121951.10417.b5
更新日期:2004-04-01 00:00:00
abstract::Cellular oxidants include a variety of reactive oxygen, nitrogen, and chlorinating species. It is well established that the increase in metabolic rate in skeletal muscle during contractile activity results in an increased production of oxidants. Failure to remove these oxidants during exercise can result in significan...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:10.1097/00005768-199907000-00011
更新日期:1999-07-01 00:00:00
abstract:PURPOSE:To determine whether quantitative methods could separate golfers with a possible dystonic cause of the "yips" from those that appear to be nondystonic. METHODS:Twenty-seven golfers completed 10 two-handed and 10 right hand-only putts. Surface EMG assessed forearm muscle co-contraction and motion detectors moni...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001687
更新日期:2018-11-01 00:00:00
abstract::Recently, Sarna et al. (Med. Sci. Sports Exerc. 25:237-244, 1993) reported increased mean life expectancy in former world class athletes. Because lifestyle is associated with longevity, we have examined whether health habits of former Finnish male athletes (N = 1274; present mean age: 57.5, range: 36-94 yr) differed f...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-199402000-00013
更新日期:1994-02-01 00:00:00
abstract:PURPOSE:This study aimed to examine the associations of physical activity and cardiorespiratory fitness (hereafter fitness) with incident glaucoma in a prospective observational study. METHODS:Physical activity was measured by self-reported leisure-time activities, and fitness was measured by maximal treadmill test. I...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001692
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:Past investigations indicate that training-related injuries are associated with certain performance-oriented measures of physical fitness and certain lifestyle characteristics. This study examined associations between injuries, direct (physiological) measures of physical fitness, and lifestyle characteristics. ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200106000-00014
更新日期:2001-06-01 00:00:00
abstract:PURPOSE:The primary aim of this study was to test the effect of a school-based physical activity intervention on adolescents' performance in mathematics. A secondary aim was to explore potential mechanisms that might explain the intervention effect. METHODS:The Activity and Motivation in Physical EDucation interventio...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1249/MSS.0000000000001730
更新日期:2018-12-01 00:00:00
abstract::The purpose of the study was to evaluate selected parameters describing performance characteristics of a free-weight and isokinetic bench press. A secondary purpose was an attempt to clarify the technique requirements essential for a successful lift. Parameters describing the free-weight condition were generated from ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1985-06-01 00:00:00
abstract:INTRODUCTION/PURPOSE:Hyperpnea and hyperinflation have been proposed as contributors to exaggerated energy demands in chronic obstructive pulmonary disease (COPD), yet there are incomplete data on exercise requirements. This study compared total-body energy demands of the internal (unloaded) and external work of cyclin...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/mss.0b013e3180383d50
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:To examine the relationship between physical activity and levels of plasma lipid peroxides, superoxide dismutase in erythrocytes (SOD), and glutathione peroxidase (GSH-Px) in whole blood activities. METHODS:Cross-sectional study in 488 Spanish women. Two categories of leisure time physical activity were define...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200205000-00014
更新日期:2002-05-01 00:00:00
abstract::Recent research has demonstrated that intracellular signaling components associated with several proinflammatory cytokines have the potential to interact with signaling pathways that regulate anabolic processes in skeletal muscle. This presentation and the ensuing brief review are intended to present a selection of th...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181b07d12
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:To determine the prevalence of reversible airway obstruction in a group of professional football training camp participants. METHODS:All attendees at a Canadian Football League team rookie preseason training camp were invited to participate in a protocol designed to elicit symptoms and signs of reversible airw...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200012000-00003
更新日期:2000-12-01 00:00:00
abstract:PURPOSE:The purpose of this investigation was to evaluate the accuracy of a new air displacement plethysmograph, BOD POD Body Composition System, for determining %fat in collegiate football players. METHODS:Body fatness was estimated from body density (Db), which was measured on the same day using the BOD POD and hydr...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199909000-00019
更新日期:1999-09-01 00:00:00