Mild cognitive impairment: hope for stability, plan for progression.

abstract：:Coronary artery disease is different in women than in men in its pathogenesis, symptoms, and prognosis. Needed is a strategy for detecting and assessing coronary disease specifically in women. This review highlights recent evidence on sex differences in coronary artery disease. ...

journal_title：Cleveland Clinic journal of medicine

authors： Bellasi A,Raggi P,Merz CN,Shaw LJ

更新日期：2007-08-01 00:00:00

abstract：:Complications of chronic gastroesophageal reflux disease (GERD) run the gamut from erosive esophagitis to esophageal cancer, but all are linked to repeated exposure of the esophagus to caustic gastric and duodenal acid. Progression from one complication to another is not clearly established across the GERD continuum, ...

journal_title：Cleveland Clinic journal of medicine

authors： Fennerty MB

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Stereotactic and computer-assisted techniques have revolutionized the diagnosis and treatment of many disorders of the brain by directing surgical instruments, the surgeon's hands, or focused radiation to an imaged target along predefined routes. METHODS:This report reviews the basic principles and techniqu...

journal_title：Cleveland Clinic journal of medicine

authors： Gomez H,Barnett GH,Estes ML,Palmer J,Magdinec M

更新日期：1993-09-01 00:00:00

abstract：:Carefully designed, monitored rehabilitation regimens can benefit patients with significant cardiac disease, such as life-threatening arrhythmias or congestive heart failure, or who have concurrent systemic disease such as diabetes. Patients with heart failure can tolerate minimal workloads but, with conditioning, the...

journal_title：Cleveland Clinic journal of medicine

authors： Pashkow FJ

更新日期：1991-01-01 00:00:00

abstract：:Women with heart failure differ from their male counterparts in a number of ways, including etiology, pattern of cardiac remodeling, and prognosis. They may even respond differently to medical therapy. But until prospective, sex-specific studies show that we should do otherwise, we recommend that women with heart fail...

journal_title：Cleveland Clinic journal of medicine

authors： Mezu U,Bott-Silverman C,Hsich E

更新日期：2007-06-01 00:00:00

abstract：:Evidence of a neurophysiologic mechanism that involves hormones from adipocytes, pancreatic islet cells, and the gastrointestinal tract implicated in both obesity and diabetes has led to a search for drugs that not only either target obesity and diabetes or reduce hemoglobin A1c, but also have weight loss as a potenti...

journal_title：Cleveland Clinic journal of medicine

authors： Esquivel MA,Lansang MC

更新日期：2017-07-01 00:00:00

abstract：:The metabolic syndrome is likely to develop in patients in whom genetic predisposition, chronic stress, negative emotion, and unhealthy lifestyle habits converge. In light of the psychophysiologic aspect of most of these factors, biofeedback, relaxation, and other psychophysiologic interventions have been studied and ...

journal_title：Cleveland Clinic journal of medicine

authors： McGrady A

更新日期：2010-07-01 00:00:00

abstract：:Obesity is epidemic and dangerous. Weight loss is difficult but worth the effort. Although new weight-loss drugs are available, there are no magic bullets: to lose weight and keep it off, people must eat less and exercise more. This article presents a practical approach on how physicians can help their patients lose w...

journal_title：Cleveland Clinic journal of medicine

authors： Weiss D

更新日期：2000-10-01 00:00:00

abstract：:Overactive bladder (OAB) is a prevalent condition in both men and women that imposes significant burdens on the patient and his or her quality of life. Nevertheless, only a small percentage of patients with OAB receive diagnosis and treatment. The identification of OAB is well within the scope of the primary care prov...

journal_title：Cleveland Clinic journal of medicine

authors： Rosenberg MT,Newman DK,Tallman CT,Page SA

更新日期：2007-05-01 00:00:00

abstract：:Elevated serum urate levels are recognized as leading to gouty arthritis, tophi formation, and uric acid kidney stones. While serum urate elevations have long been associated with renal disease, they are not usually considered to have a causal role in kidney dysfunction. However, recent epidemiologic studies have iden...

journal_title：Cleveland Clinic journal of medicine

authors： Edwards NL

更新日期：2008-07-01 00:00:00

abstract：:Genetics may account for much of the variability in our patients' responses to drug therapies. This article offers the clinician an up-to-date overview of pharmacogenomic testing, discussing implications and limitations of emerging validated tests relevant to the use of warfarin (Coumadin), clopidogrel (Plavix), stati...

journal_title：Cleveland Clinic journal of medicine

authors： Kitzmiller JP,Groen DK,Phelps MA,Sadee W

更新日期：2011-04-01 00:00:00

abstract：:We reviewed the population of a surgical intensive care unit from July 1, 1987 to June 30, 1988, adjusting for severity of illness using the APACHE II system. Nineteen different departments admitted a total of 613 patients to the surgical intensive care unit. Predicted mortality was 22.9%; actual mortality was 15.7%. ...

journal_title：Cleveland Clinic journal of medicine

authors： Lockrem JD,Lopez E,Gallagher J,Church GE,Estafanous FG

更新日期：1991-11-01 00:00:00

abstract：:The neurohormone arginine vasopressin (AVP) is a promising target in the treatment of heart failure because AVP promotes congestion and hyponatremia, each of which is associated with poor outcomes. Diuretics are standard therapy for heart failure, but they have several limitations, including worsening renal function a...

journal_title：Cleveland Clinic journal of medicine

authors： Gheorghiade M

更新日期：2006-06-01 00:00:00

abstract：:Interleukin 1 (IL-1) is a potential target of therapy in COVID-19 during the severe respiratory-inflammatory phase ("cytokine release syndrome"), when pulmonary macrophages are hyperactivated, releasing IL-1 and other cytokines. Preliminary evidence indicates that anakinra and canakinumab, drugs that block the action ...

journal_title：Cleveland Clinic journal of medicine

authors： Calabrese LH,Calabrese C

更新日期：2020-07-09 00:00:00

abstract：:Infection with human immunodeficiency virus (HIV), hepatitis B virus (HBV), or hepatitis C virus (HCV) can cause rapidly progressive renal disease, so prompt recognition and management are critical. Viral glomerulonephropathy can now often be successfully managed with a specific combination of antiviral therapy, immun...

journal_title：Cleveland Clinic journal of medicine

authors： Appel G

更新日期：2007-05-01 00:00:00

abstract：:Biochemical markers of bone turnover provide clinically useful evidence of the normal and pathologic processes that reflect bone cell activity in the skeleton. Understanding the behavior of markers of bone formation and bone resorption should aid in managing patients with a variety of skeletal disorders. ...

journal_title：Cleveland Clinic journal of medicine

authors： Singer FR,Eyre DR

更新日期：2008-10-01 00:00:00

abstract：:Numerous immunomodulating agents are currently being studied in clinical trials for the treatment of COVID-19, including interferon therapies. Interferons are naturally occurring host antiviral proteins upstream of the inflammatory pathway that are released by host cells in response to the presence of viral pathogens....

journal_title：Cleveland Clinic journal of medicine

authors： Calabrese LH,Lenfant T,Calabrese C

更新日期：2020-12-03 00:00:00

abstract：:Fraud in scientific research is a widespread problem. It can involve falsifying data or documents, or knowingly failing to comply with regulations protecting research participants. Fraud can be committed by individuals, institutions, or corporations; in the context of research, fraud often is motivated by consideratio...

journal_title：Cleveland Clinic journal of medicine

authors： Sheehan JG

更新日期：2007-03-01 00:00:00

abstract：:Of the imaging techniques currently available to evaluate women for breast disease, mammography remains the mainstay of breast cancer screening, but recent guidelines have included magnetic resonance imaging (MRI) for the screening of some women at high risk. Whole-breast ultrasonography for screening has not been est...

journal_title：Cleveland Clinic journal of medicine

authors： Nemec CF,Listinsky J,Rim A

更新日期：2007-12-01 00:00:00

abstract：:Newer theories suggest that patients with fibromyalgia have a biologic predisposition to perceiving pain with more sensitivity than people without fibromyalgia. Several biologic triggers are implicated as possibly initiating or worsening the symptoms of fibromyalgia. Treatments to manage pain, help with sleep, and, wh...

journal_title：Cleveland Clinic journal of medicine

authors： Clauw DJ

更新日期：2001-10-01 00:00:00

abstract：:Caring for very important persons (VIPs), including celebrities and royalty, presents medical, organizational, and administrative challenges, often referred to collectively as the "VIP syndrome." The situation often pressures the health care team to bend the rules by which they usually practice medicine. Caring for VI...

journal_title：Cleveland Clinic journal of medicine

authors： Guzman JA,Sasidhar M,Stoller JK

更新日期：2011-02-01 00:00:00

abstract：:Focal acantholytic dyskeratosis consistent with the clinical and histological features of Darier's type of transient acantholytic dermatosis occurred in a man with myelodysplasia. Topical steroids and systemic antihistamines provided temporary and moderate relief from pruritus, but failed to control the dermatosis. ...

journal_title：Cleveland Clinic journal of medicine

authors： Rockley PF,Bergfeld WF,Tomecki KJ,Brydon JK

更新日期：1990-09-01 00:00:00

abstract：:Clinical imaging and serologic testing are increasingly replacing biopsy for diagnosing hepatic diseases. However, more biopsies are being done to stage and grade hepatitis C and fatty liver disease, to diagnose space-occupying lesions (typically with fine-needle aspiration biopsy), and to assess response to therapy. ...

journal_title：Cleveland Clinic journal of medicine

authors： Siegel CA,Silas AM,Suriawinata AA,van Leeuwen DJ

更新日期：2005-03-01 00:00:00

abstract：:Research into heart rate variability (HRV) and respiration over the past 150 years has led to the insight that HRV with deep breathing (HRVdb) is a highly sensitive measure of cardiovagal or parasympathetic cardiac function. This sensitivity makes HRVdb an important part of the battery of cardiovascular autonomic func...

journal_title：Cleveland Clinic journal of medicine

authors： Shields RW Jr

更新日期：2009-04-01 00:00:00

abstract：:One of the most important deficiency states associated with chronic renal failure is profound anemia. While it has been possible to identify differing types of anemia in patients receiving dialysis support, and thus correct the secondary causes, most patients continue to exhibit symptoms and signs of the anemic state....

journal_title：Cleveland Clinic journal of medicine

authors： Paganini EP,Garcia J,Abdulhadi M,Lathim D,Giesman J,Weick JK

更新日期：1989-01-01 00:00:00

abstract：:Exercise stress electrocardiography is unreliable as a test for obstructive coronary artery disease (CAD) if the patient has left bundle branch block. The authors provide an algorithm for using alternative tests: exercise stress echocardiography, dobutamine echocardiography, computed tomographic (CT) angiography, and ...

journal_title：Cleveland Clinic journal of medicine

authors： Xu B,Cremer P,Jaber W,Moir S,Harb SC,Rodriguez LL

更新日期：2018-03-01 00:00:00

abstract：:The role of the immune system in the pathogenesis of beryllium lung disease has been suspected for years. The observation of cutaneous hypersensitivity to beryllium led to the development of the lymphocyte blast transformation test; the test clearly distinguishes between healthy subjects, who show little or no blast t...

journal_title：Cleveland Clinic journal of medicine

authors： Deodhar SD,Barna BP

更新日期：1991-03-01 00:00:00

abstract：:Gout management requires a comprehensive strategy that considers both acute and chronic aspects of the disease. Acute gout flares should be treated with anti-inflammatory agents as rapidly as possible. The underlying hyperuricemia may be treated with urate-lowering agents initiated at a time appropriate for the indivi...

journal_title：Cleveland Clinic journal of medicine

authors： Schumacher HR Jr,Chen LX

更新日期：2008-07-01 00:00:00

abstract：:Obstructive sleep apnea (OSA) is a serious condition associated with impaired quality of life, depression, drowsy driving and motor vehicle accidents, metabolic disease, and cognitive decline. The mechanisms accounting for OSA and metabolic disease include hypoxia, sleep fragmentation, and systemic inflammation. OSA a...

journal_title：Cleveland Clinic journal of medicine

authors： Walia HK

更新日期：2019-09-01 00:00:00

abstract：:In patients with morbid obesity, surgery is the only treatment known to produce sustained weight loss and to reduce comorbidities. Traditional (open) gastric bypass surgery is associated with postoperative complications that include wound infection, pulmonary embolism, and pneumonia. Laparoscopic techniques achieve si...

journal_title：Cleveland Clinic journal of medicine

authors： Brody F

更新日期：2004-04-01 00:00:00