How to help your patients lose weight: current therapy for obesity.

abstract：:Obesity is a potent risk factor for the development and progression of type 2 diabetes, and weight loss is a key component of diabetes management. Bariatric surgery results in significant weight loss and remission of diabetes in most patients. After surgery, glycemic control is restored by a combination of enforced ca...

journal_title：Cleveland Clinic journal of medicine

authors： Kashyap SR,Gatmaitan P,Brethauer S,Schauer P

更新日期：2010-07-01 00:00:00

abstract：:To date, there are no effective antiviral medications for COVID-19. Drug repurposing, a strategy that uses existing drugs, offers potential prevention and treatment options for COVID-19. We discuss one treatment strategy that combines anti-inflammatory (melatonin) and antiviral (toremifene) agents for patients infecte...

journal_title：Cleveland Clinic journal of medicine

authors： Cheng F,Rao S,Mehra R

更新日期：2020-06-30 00:00:00

abstract：:Ebola virus causes a hemorrhagic fever with a high case-fatality rate. Treatment remains supportive although a variety of specific treatments are still in the early stages of investigation. This report reviews the clinical virology of Ebola virus, the reported proposed treatments, and the current outbreak. ...

journal_title：Cleveland Clinic journal of medicine

authors： Brizendine KD

更新日期：2014-12-01 00:00:00

abstract：:Clinicians are bombarded with information daily by social media, mainstream television news, e-mail, and print and online reports. They usually do not have much control over these information streams and thus are passive recipients, which means they get more noise than signal. Accessing, absorbing, organizing, storing...

journal_title：Cleveland Clinic journal of medicine

authors： Mehta NB,Martin SA,Maypole J,Andrews R

更新日期：2016-08-01 00:00:00

abstract：:The most important component of the treatment of irritable bowel syndrome (IBS) is to establish a therapeutic physician-patient relationship, coupled with patient education. We describe a stepwise approach to management, including judicious use of invasive tests, and setting realistic treatment goals that address the ...

journal_title：Cleveland Clinic journal of medicine

authors： Shen B,Soffer E

更新日期：2001-03-01 00:00:00

abstract：:Extent of resection in temporal lobectomy has been traditionally based on intraoperative linear measurements. The complex geometrical contour of the temporal lobe limits the precision and accuracy of such measurements, and it is often difficult to verify the extent of actual resection after surgery. The authors propos...

journal_title：Cleveland Clinic journal of medicine

authors： Awad IA,Katz A,Lüders H,Weinstein M

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Coronary artery disease is a major cause of death in transplant recipients. PURPOSE:To review current approaches for the detection, evaluation, and treatment of coronary artery disease in transplant recipients. SUMMARY:Renal transplantation promotes the development of coronary artery disease primarily beca...

journal_title：Cleveland Clinic journal of medicine

authors： Braun WE,Marwick TH

更新日期：1994-09-01 00:00:00

abstract：:Focal acantholytic dyskeratosis consistent with the clinical and histological features of Darier's type of transient acantholytic dermatosis occurred in a man with myelodysplasia. Topical steroids and systemic antihistamines provided temporary and moderate relief from pruritus, but failed to control the dermatosis. ...

journal_title：Cleveland Clinic journal of medicine

authors： Rockley PF,Bergfeld WF,Tomecki KJ,Brydon JK

更新日期：1990-09-01 00:00:00

abstract：:Primary care physicians must initiate a discussion of overactive bladder and urinary incontinence with their patients who are at risk. A stepwise approach to evaluation and diagnosis and the use of systematic evaluation and treatment algorithms suitable to the primary care setting will improve identification and effec...

journal_title：Cleveland Clinic journal of medicine

authors： Rosenberg MT,Dmochowski RR

更新日期：2005-02-01 00:00:00

abstract：:Patients with pulmonary arterial hypertension (PAH) may present to internists, rheumatologists, cardiologists, or pulmonologists. This breadth of clinicians who encounter PAH patients, together with the complicated nature of PAH as a disease entity, argues for a shared-care approach to the management of these patients...

journal_title：Cleveland Clinic journal of medicine

authors： Mughal MM,Mandell B,James K,Stelmach K,Minai OA

更新日期：2003-04-01 00:00:00

abstract：:Patients with muscle diseases are often seen initially by general practitioners. This article reviews how to evaluate and manage such patients, including those taking a statin, how to interpret creatine kinase (CK) test results, and how to recognize common as well as potentially dangerous myopathies. ...

journal_title：Cleveland Clinic journal of medicine

authors： Oddis CV

更新日期：2019-10-01 00:00:00

abstract：:Giant cell arteritis is a common systemic vasculitis that affects the elderly and has a variable clinical presentation. Physicians should be aware of its different clinical phenotypes so that they can recognize it early and promptly initiate glucocorticoids, the mainstay of therapy. Clinicians should also be familiar ...

journal_title：Cleveland Clinic journal of medicine

authors： Rinden T,Miller E,Nasr R

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Certain fluorocarbon polymers can produce a clinical syndrome called polymer fume fever when the products of pyrolysis are inhaled. SUMMARY:A previously healthy 21-year-old white man presented with severe chest tightness, difficulty in breathing, pyrexia, nausea, vomiting, and a dry irritating cough. These ...

journal_title：Cleveland Clinic journal of medicine

authors： Silver MJ,Young DK

更新日期：1993-11-01 00:00:00

abstract：:Pancreas transplantation can improve quality of life for patients with type 1 diabetes by eliminating hypoglycemic and hyperglycemic episodes, the need for insulin injections, frequent self-monitoring of blood glucose levels, and dietary restrictions. Increasing evidence suggests that it may slow the progression of lo...

journal_title：Cleveland Clinic journal of medicine

authors： Mayes JT,Dennis VW,Hoogwerf BJ

更新日期：2000-04-01 00:00:00

abstract：:The neurohormone arginine vasopressin (AVP) is a promising target in the treatment of heart failure because AVP promotes congestion and hyponatremia, each of which is associated with poor outcomes. Diuretics are standard therapy for heart failure, but they have several limitations, including worsening renal function a...

journal_title：Cleveland Clinic journal of medicine

authors： Gheorghiade M

更新日期：2006-06-01 00:00:00

abstract：:Inadvertent malpositioning of a cardiac implantable electronic device lead into the left ventricle is a rare complication of transvenous pacing and defibrillation. Rapid identification of lead position is critical during implantation and just after the procedure, with immediate correction required if malpositioning is...

journal_title：Cleveland Clinic journal of medicine

authors： Trohman RG,Sharma PS

更新日期：2018-01-01 00:00:00

abstract：:Concern has been raised about whether the fluid retention caused by thiazolidinediones (TZDs, ie, rosiglitazone and pioglitazone) can cause or exacerbate congestive heart failure. Although fluid retention is a worrisome side effect of TZDs, current evidence does not link fluid retention caused by TZDs with worsening h...

journal_title：Cleveland Clinic journal of medicine

authors： Tang WH

更新日期：2006-04-01 00:00:00

abstract：:Elderly patients pose unique challenges perioperatively. They are more likely than younger surgical patients to be mentally and physically compromised at baseline, which increases the risk of delirium and postoperative cognitive dysfunction. Postoperative cognitive risk can be predicted, however, and effective strateg...

journal_title：Cleveland Clinic journal of medicine

authors： Palmer RM

更新日期：2009-11-01 00:00:00

abstract：:Complications of chronic gastroesophageal reflux disease (GERD) run the gamut from erosive esophagitis to esophageal cancer, but all are linked to repeated exposure of the esophagus to caustic gastric and duodenal acid. Progression from one complication to another is not clearly established across the GERD continuum, ...

journal_title：Cleveland Clinic journal of medicine

authors： Fennerty MB

更新日期：2003-11-01 00:00:00

abstract：:Often patients with immune hemolytic anemias present with symptoms that are common in anemia of any cause. In the different types of immune hemolytic anemia, red blood cells are destroyed by processes mediated by antibodies. This article reviews the pathophysiology, diagnosis, and treatment of this group of diseases. ...

journal_title：Cleveland Clinic journal of medicine

authors： Domen RE

更新日期：1998-02-01 00:00:00

abstract：:The role of the immune system in the pathogenesis of beryllium lung disease has been suspected for years. The observation of cutaneous hypersensitivity to beryllium led to the development of the lymphocyte blast transformation test; the test clearly distinguishes between healthy subjects, who show little or no blast t...

journal_title：Cleveland Clinic journal of medicine

authors： Deodhar SD,Barna BP

更新日期：1991-03-01 00:00:00

abstract：:Patients with systemic lupus erythematosus (SLE, lupus) have a markedly better survival rate today than they did 50 years ago, but they face a greater risk of cancer, cardiovascular disease, and osteoporosis at early ages. With better understanding of the immunological mechanisms of the disease, new avenues of therapy...

journal_title：Cleveland Clinic journal of medicine

authors： Manzi S

更新日期：2009-02-01 00:00:00

abstract：:Preliminary clinical trials suggest that therapeutic hypothermia might improve the outcomes of patients with acute stroke. Definitive trials are under way. ...

journal_title：Cleveland Clinic journal of medicine

authors： Hammer MD,Krieger DW

更新日期：2002-10-01 00:00:00

abstract：:A case is reported of lambda light chain multiple myeloma complicated by a myelomatous pleural effusion. Pleural effusions are uncommon in multiple myeloma, and most are secondary to nonmalignant causes. The clinical characteristics, natural history and pathophysiology of myelomatous pleural effusions are reviewed. ...

journal_title：Cleveland Clinic journal of medicine

authors： Abbate SL,Jaff MR,Fishleder AJ,Meeker DP

更新日期：1991-05-01 00:00:00

abstract：:Nephrotic syndrome can now be treated effectively in most cases. All patients should be treated with a low-salt diet, diuretics to reduce edema, and statins to normalize serum lipid concentrations. Patients with nephrotic syndrome are prone to deep vein thrombophlebitis, renal vein thrombosis, and pulmonary emboli. De...

journal_title：Cleveland Clinic journal of medicine

authors： Appel GB

更新日期：2006-02-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is an important cause of death in patients with liver disease, and its incidence appears to be rising in the United States. Because early diagnosis improves the chances of survival, it is important to identify patients who would benefit from surveillance. Once HCC is suspected on surveil...

journal_title：Cleveland Clinic journal of medicine

authors： Murali AR,Romero-Marrero C,Aucejo F,Menon KV

更新日期：2013-10-01 00:00:00

abstract：:Overactive bladder (OAB) is a prevalent condition in both men and women that imposes significant burdens on the patient and his or her quality of life. Nevertheless, only a small percentage of patients with OAB receive diagnosis and treatment. The identification of OAB is well within the scope of the primary care prov...

journal_title：Cleveland Clinic journal of medicine

authors： Rosenberg MT,Newman DK,Tallman CT,Page SA

更新日期：2007-05-01 00:00:00

abstract：:Special problems of Asian patients have considerable impact on diagnosis and treatment, and the number of persons of Asian ancestry seen in primary care in the United States is increasing. Knowledge of how to provide optimal care despite language barriers, low socioeconomic status, different health beliefs and practic...

journal_title：Cleveland Clinic journal of medicine

authors： Jin XW,Slomka J,Blixen CE

更新日期：2002-01-01 00:00:00

abstract：:Non-Q-wave infarction is associated with a significant incidence of infarction and death. We followed 52 patients who underwent percutaneous transluminal coronary angioplasty (PTCA) within three months of non-Q-wave myocardial infarction. Thirty-eight patients had single-vessel disease, 12 had double-vessel disease, a...

journal_title：Cleveland Clinic journal of medicine

authors： Bellamy GR,McEniery PT,Zaidi AR,Hollman J

更新日期：1989-03-01 00:00:00

abstract：:Tailored care will increasingly become the hallmark of treatment for patients with hypertension in the 1990s. In mildly hypertensive patients, treatment should begin with nonpharmacologic approaches to lower blood pressure and reduce the patient's cardiovascular risk profile. The ever-increasing array of antihypertens...

journal_title：Cleveland Clinic journal of medicine

authors： Vidt DG

更新日期：1991-05-01 00:00:00