Pancreas transplantation in type 1 diabetes: hope vs reality.

abstract：:By incorporating additional data, clinicians can transform the exercise stress test from a poor diagnostic test to a good prognostic one. These additional data include indices of how the patient's heart rate and blood pressure respond to exercise. Computerized measures of electrocardiographic ST-segment changes that a...

journal_title：Cleveland Clinic journal of medicine

authors： Lauer MS

更新日期：1999-05-01 00:00:00

abstract：:Abnormal hemodynamic responses to exercise treadmill testing may indicate an increased risk of coronary events and death, even if evidence of ischemia is absent. Exercise duration and the blood pressure, heart rate, and heart rhythm responses to exercise have prognostic significance. ...

journal_title：Cleveland Clinic journal of medicine

authors： Miller TD

更新日期：2008-06-01 00:00:00

abstract：:Several studies have documented that hypercholesterolemia is common in American children. Other studies have shown that elevated cholesterol levels in childhood remain elevated well into adult life. Autopsy studies of adolescents have also found a strong positive correlation between antemortem cholesterol levels and e...

journal_title：Cleveland Clinic journal of medicine

authors： Garcia RE,Moodie DS

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Nicotinic acid, widely used to lower serum cholesterol levels, may rarely cause cholestatic jaundice. SUMMARY:A 61-year-old white man with hypercholesterolemia complained of marked pruritus and became jaundiced after taking 3.0 g of crystalline nicotinic acid daily for 13 months. His total serum bilirubin l...

journal_title：Cleveland Clinic journal of medicine

authors： Patel SD,Taylor HC

更新日期：1994-01-01 00:00:00

abstract：:The American Heart Association issued a science advisory on depression and coronary heart disease (CHD) in 2008. This paper reviews the purpose and content of the advisory and discusses reactions and new information that have followed the advisory's release. Both the advisory and subsequent data support routine screen...

journal_title：Cleveland Clinic journal of medicine

authors： Bigger JT,Glassman AH

更新日期：2010-07-01 00:00:00

abstract：:Omega-3 fatty acids are abundant in fish oil. A high dietary intake of omega-3 fatty acids has been strongly linked to lower rates of cardiovascular disease in epidemiologic studies. Fish oil supplements lower triglyceride levels and may have other benefits such as preventing arrhythmias, reducing inflammation (althou...

journal_title：Cleveland Clinic journal of medicine

authors： Chan EJ,Cho L

更新日期：2009-04-01 00:00:00

abstract：:Intravascular ultrasonography (IVUS) can precisely measure plaque burden and is being used to test new drug therapies. Other imaging tests may also prove useful to monitor treatment of atherosclerosis and identify populations at risk for coronary artery disease (CAD). ...

journal_title：Cleveland Clinic journal of medicine

authors： Schoenhagen P,Nissen SE

更新日期：2005-06-01 00:00:00

abstract：:Although the safety profiles of drug-eluting stents are similar to those of bare metal stents in the short term, concern has arisen about their potential for late thrombosis (occurring > 30 days after implantation). Stent thrombosis is rare but potentially devastating and can result in ST-segment elevation myocardial ...

journal_title：Cleveland Clinic journal of medicine

authors： Rabbat MG,Bavry AA,Bhatt DL,Ellis SG

更新日期：2007-02-01 00:00:00

abstract：:The neurohormone arginine vasopressin (AVP) is a promising target in the treatment of heart failure because AVP promotes congestion and hyponatremia, each of which is associated with poor outcomes. Diuretics are standard therapy for heart failure, but they have several limitations, including worsening renal function a...

journal_title：Cleveland Clinic journal of medicine

authors： Gheorghiade M

更新日期：2006-06-01 00:00:00

abstract：:Mounting evidence suggests that depression, anxiety, and hostility/anger may each be an independent risk factor for acute coronary syndrome (ACS) occurrence. Data specific to the role of these negative emotional states in predisposing to imminent ACS risk are limited, however. Additionally, a number of studies have in...

journal_title：Cleveland Clinic journal of medicine

authors： Davidson KW

更新日期：2008-03-01 00:00:00

abstract：:Stress echocardiography is a cost-effective and reliable diagnostic test for patients with suspected coronary artery disease. Stress echocardiography should be used in preference to exercise electrocardiography as the primary test in patients with uninterpretable ST segments. It is attractive for use as the primary te...

journal_title：Cleveland Clinic journal of medicine

authors： Marwick T

更新日期：1995-07-01 00:00:00

abstract：:SARS-CoV-2, the virus that causes COVID-19, is transmitted through respiratory secretions and saliva. The virus can also live for short periods of time (1 to several hours) on fomites such as doorknobs, handrails, and tables. Aerosolization of the virus can occur during procedures including bronchoscopy, endotracheal ...

journal_title：Cleveland Clinic journal of medicine

authors： Miller R,Englund K

更新日期：2020-05-14 00:00:00

abstract：:Cutaneous changes may be the first clue that a patient has liver disease. Recognizing these signs is crucial to diagnosing liver conditions early. Here we describe the spectrum of skin manifestations that may be found in various liver diseases. ...

journal_title：Cleveland Clinic journal of medicine

authors： Hazin R,Abu-Rajab Tamimi TI,Abuzetun JY,Zein NN

更新日期：2009-10-01 00:00:00

abstract：:Obesity is a potent risk factor for the development and progression of type 2 diabetes, and weight loss is a key component of diabetes management. Bariatric surgery results in significant weight loss and remission of diabetes in most patients. After surgery, glycemic control is restored by a combination of enforced ca...

journal_title：Cleveland Clinic journal of medicine

authors： Kashyap SR,Gatmaitan P,Brethauer S,Schauer P

更新日期：2010-07-01 00:00:00

abstract：:Primary care physicians must initiate a discussion of overactive bladder and urinary incontinence with their patients who are at risk. A stepwise approach to evaluation and diagnosis and the use of systematic evaluation and treatment algorithms suitable to the primary care setting will improve identification and effec...

journal_title：Cleveland Clinic journal of medicine

authors： Rosenberg MT,Dmochowski RR

更新日期：2005-02-01 00:00:00

abstract：:During a 10-year period, 60 patients with confirmed diagnoses of pheochromocytoma underwent a total of 63 surgical procedure. To control extreme blood pressure elevations, 6 patients received phenoxybenzamine preoperatively and 28 patients received prazosin. The remaining 29 patients received neither drug. Intravenous...

journal_title：Cleveland Clinic journal of medicine

authors： Boutros AR,Bravo EL,Zanettin G,Straffon RA

更新日期：1990-10-01 00:00:00

abstract：:Complications of chronic gastroesophageal reflux disease (GERD) run the gamut from erosive esophagitis to esophageal cancer, but all are linked to repeated exposure of the esophagus to caustic gastric and duodenal acid. Progression from one complication to another is not clearly established across the GERD continuum, ...

journal_title：Cleveland Clinic journal of medicine

authors： Fennerty MB

更新日期：2003-11-01 00:00:00

abstract：:Recommendations exist for preparticipation physical examinations, but there is no national standard, and the recommendations are not widely followed. The most common reasons for denying clearance to play are musculoskeletal conditions, hypertension, and visual acuity problems. Although detecting potentially life-threa...

journal_title：Cleveland Clinic journal of medicine

authors： Mick TM,Dimeff RJ

更新日期：2004-07-01 00:00:00

abstract：:Hirsutism is a source of significant anxiety in women. While polycystic ovary syndrome or other endocrine conditions are responsible for excess androgen in many patients, other patients have normal menses and normal androgen levels ("idiopathic" hirsutism). The goal of the evaluation is to rule out any underlying path...

journal_title：Cleveland Clinic journal of medicine

authors： Harrison S,Somani N,Bergfeld WF

更新日期：2010-06-01 00:00:00

abstract：:Many patients are donating their own blood before surgery to avoid blood-borne infections, often on the advice of their physicians. But autologous blood transfusion, while safer than allogeneic transfusion, is not completely risk-free. It is also expensive, its benefits are difficult to assess, and its increasing popu...

journal_title：Cleveland Clinic journal of medicine

authors： Domen RE

更新日期：1996-09-01 00:00:00

abstract：:Studies published during the past year on the treatment of several infectious diseases provide valuable information that should enable us to treat our patients more effectively. Among those findings: Oral vancomycin (Vancocin) is superior to oral metronidazole (Flagyl) for treating patients with severe Clostridium dif...

journal_title：Cleveland Clinic journal of medicine

authors： Longworth DL

更新日期：2008-08-01 00:00:00

abstract：:Although the literature is limited, early evidence suggests that patients with chronic kidney disease, end-stage kidney disease, and kidney transplant recipients are at increased risk for severe COVID-19 disease and death. Hence, management should focus on both infection prevention and treatment. There is currently a ...

journal_title：Cleveland Clinic journal of medicine

authors： Radhakrishnan Y,Hassanein M,Stephany B

更新日期：2020-12-03 00:00:00

abstract：:A case of pacemaker lead dysfunction with subsequent removal by a unique transvenous extraction system is presented. This technique allows detailed examination of the extracted pacemaker lead and identification of unsuspected causes of lead failure. Information relative to specific causes of lead failure may result in...

journal_title：Cleveland Clinic journal of medicine

authors： Brodell GK,Wilkoff BL

更新日期：1992-01-01 00:00:00

abstract：:The history and physical examination, rather than routine laboratory, cardiovascular, and pulmonary testing, are the most important components of the preoperative evaluation. The history should include a complete review of systems (especially cardiovascular and pulmonary), medication history, allergies, surgical and a...

journal_title：Cleveland Clinic journal of medicine

authors： Michota FA,Frost SD

更新日期：2004-01-01 00:00:00

abstract：:Newer theories suggest that patients with fibromyalgia have a biologic predisposition to perceiving pain with more sensitivity than people without fibromyalgia. Several biologic triggers are implicated as possibly initiating or worsening the symptoms of fibromyalgia. Treatments to manage pain, help with sleep, and, wh...

journal_title：Cleveland Clinic journal of medicine

authors： Clauw DJ

更新日期：2001-10-01 00:00:00

abstract：:Recent advances in our understanding of the diagnosis, imaging, pathology, and clinical monitoring of multiple sclerosis (MS) have significantly increased our ability to successfully treat this often perplexing neurologic disorder. Magnetic resonance imaging (MRI) is now integral to the diagnostic process. Treatment o...

journal_title：Cleveland Clinic journal of medicine

authors： Fox RJ,Bethoux F,Goldman MD,Cohen JA

更新日期：2006-01-01 00:00:00

abstract：:Cancer patients and their families often ask their primary care physicians if a new treatment reported in the news can help them. Physicians familiar with the long and complicated process of oncologic clinical trials are in the best position to assess the potential for clinical benefit from a new antineoplastic therap...

journal_title：Cleveland Clinic journal of medicine

authors： Markman M

更新日期：2002-05-01 00:00:00

abstract：:Although atrial fibrillation is well tolerated by most patients, in some patients the consequences may be severe. The Maze procedure is a new open-heart operation that creates a carefully designed maze of incisions in the atrial myocardium; this maze then acts as an electrical conduit to channel atrial impulses from t...

journal_title：Cleveland Clinic journal of medicine

authors： McCarthy PM,Castle LW,Trohman RG,Simmons TW,Maloney JD,Klein AL,White RD,Cox JL

更新日期：1993-03-01 00:00:00

abstract：:The decline in testosterone with age has been associated with specific physical changes that affect quality of life and life expectancy, although a cause-and-effect relationship is yet to be established. While female menopause is rapid and well described, "male menopause" or androgen decline in older men is gradual an...

journal_title：Cleveland Clinic journal of medicine

authors： McGill JJ,Shoskes DA,Sabanegh ES

更新日期：2012-11-01 00:00:00

abstract：:Often patients with immune hemolytic anemias present with symptoms that are common in anemia of any cause. In the different types of immune hemolytic anemia, red blood cells are destroyed by processes mediated by antibodies. This article reviews the pathophysiology, diagnosis, and treatment of this group of diseases. ...

journal_title：Cleveland Clinic journal of medicine

authors： Domen RE

更新日期：1998-02-01 00:00:00