Do thiazolidinediones cause heart failure? A critical review.

abstract：:One of the factors that contribute to the progressively declining course of heart failure could be sleep apnea. Whether treating sleep apnea improves the clinical outcomes of patients with heart failure needs to be tested in randomized clinical trials. ...

journal_title：Cleveland Clinic journal of medicine

authors： Wexler L,Javaheri S

更新日期：2005-10-01 00:00:00

abstract：:Finding the optimal combination of drugs in the correct dosages, which requires careful monitoring over time, is key to slowing the disease process and prolonging life. For most patients, treating heart failure involves correcting underlying left ventricular dysfunction, thereby slowing the remodeling process. ...

journal_title：Cleveland Clinic journal of medicine

authors： Basile JN

更新日期：2002-02-01 00:00:00

abstract：:Anticonvulsant hypersensitivity syndrome, a potentially fatal but rare reaction, manifests as rash, fever, tender lymphadenopathy, hepatitis, and eosinophilia. To manage hypersensitivity syndrome successfully, one must recognize the symptoms early, stop the offending drug immediately, and substitute a safe, alternativ...

journal_title：Cleveland Clinic journal of medicine

authors： Hamer HM,Morris HH

更新日期：1999-04-01 00:00:00

abstract：:Several theories have been put forth to explain the pathogenesis of syringomyelia, the formation of longitudinal, fluid-filled cavities within the spinal cord. Chief among them is Gardner's hydrodynamic theory, widely accepted for more than two decades. Gardner attributed the genesis of syringomyelia to craniospinal p...

journal_title：Cleveland Clinic journal of medicine

authors： Pillay PK,Awad IA,Hahn JF

更新日期：1992-07-01 00:00:00

abstract：:The clinical care of women with epilepsy entails special considerations over the life span. Endogenous depression is more prevalent in persons with epilepsy than in the general population and may be unrecognized. Seizure frequency may be influenced by hormonal fluctuations, as reflected by catamenial patterns in up to...

journal_title：Cleveland Clinic journal of medicine

authors： Penovich PE,Eck KE,Economou VV

更新日期：2004-02-01 00:00:00

abstract：:Fraud in scientific research is a widespread problem. It can involve falsifying data or documents, or knowingly failing to comply with regulations protecting research participants. Fraud can be committed by individuals, institutions, or corporations; in the context of research, fraud often is motivated by consideratio...

journal_title：Cleveland Clinic journal of medicine

authors： Sheehan JG

更新日期：2007-03-01 00:00:00

abstract：:SCS is an efficacious, reversible, and safe therapy that improves quality of life, increases exercise tolerance, and relieves angina pectoris, but clinical trials in North America are needed to confirm the data coming from Europe. Neuronal convergence onto STT cells underlies the referred pain associated with angina p...

journal_title：Cleveland Clinic journal of medicine

authors： Foreman RD

更新日期：2007-02-01 00:00:00

abstract：:Carefully designed, monitored rehabilitation regimens can benefit patients with significant cardiac disease, such as life-threatening arrhythmias or congestive heart failure, or who have concurrent systemic disease such as diabetes. Patients with heart failure can tolerate minimal workloads but, with conditioning, the...

journal_title：Cleveland Clinic journal of medicine

authors： Pashkow FJ

更新日期：1991-01-01 00:00:00

abstract：:Transitions of care-when patients move from one health care facility to another or back home-that are poorly executed result in adverse effects for patients. Fortunately, programs can be implemented that enhance collaboration across care settings and improve outcomes including reducing hospital readmission rates. ...

journal_title：Cleveland Clinic journal of medicine

authors： Li J,Young R,Williams MV

更新日期：2014-05-01 00:00:00

abstract：:The aromatase inhibitors are established first-line drugs for treating metastatic breast cancer in postmenopausal women, and are gaining acceptance as adjuvant treatment as well. ...

journal_title：Cleveland Clinic journal of medicine

authors： Hill J,Moore H

更新日期：2002-07-01 00:00:00

abstract：:The decline in testosterone with age has been associated with specific physical changes that affect quality of life and life expectancy, although a cause-and-effect relationship is yet to be established. While female menopause is rapid and well described, "male menopause" or androgen decline in older men is gradual an...

journal_title：Cleveland Clinic journal of medicine

authors： McGill JJ,Shoskes DA,Sabanegh ES

更新日期：2012-11-01 00:00:00

abstract：:Newer theories suggest that patients with fibromyalgia have a biologic predisposition to perceiving pain with more sensitivity than people without fibromyalgia. Several biologic triggers are implicated as possibly initiating or worsening the symptoms of fibromyalgia. Treatments to manage pain, help with sleep, and, wh...

journal_title：Cleveland Clinic journal of medicine

authors： Clauw DJ

更新日期：2001-10-01 00:00:00

abstract：:Patients with alcohol use disorder (AUD) are at higher risk of pneumonia and of poor outcomes. This article reviews the etiology of pneumonia in patients with AUD, its impact on mortality and resource utilization, and its implications for treatment. ...

journal_title：Cleveland Clinic journal of medicine

authors： Gupta NM,Deshpande A,Rothberg MB

更新日期：2020-07-31 00:00:00

abstract：:Vascular surgery is associated with a high risk of perioperative morbidity and mortality that is partly attributable to inflammatory stress induced by the surgical procedure. Preoperative initiation of a long-acting statin is a strategy intended to reduce the inflammatory stress response and the excess risk associated...

journal_title：Cleveland Clinic journal of medicine

authors： Poldermans D

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Coronary artery disease is a major cause of death in transplant recipients. PURPOSE:To review current approaches for the detection, evaluation, and treatment of coronary artery disease in transplant recipients. SUMMARY:Renal transplantation promotes the development of coronary artery disease primarily beca...

journal_title：Cleveland Clinic journal of medicine

authors： Braun WE,Marwick TH

更新日期：1994-09-01 00:00:00

abstract：:Elevated serum urate levels are recognized as leading to gouty arthritis, tophi formation, and uric acid kidney stones. While serum urate elevations have long been associated with renal disease, they are not usually considered to have a causal role in kidney dysfunction. However, recent epidemiologic studies have iden...

journal_title：Cleveland Clinic journal of medicine

authors： Edwards NL

更新日期：2008-07-01 00:00:00

abstract：:We reviewed the population of a surgical intensive care unit from July 1, 1987 to June 30, 1988, adjusting for severity of illness using the APACHE II system. Nineteen different departments admitted a total of 613 patients to the surgical intensive care unit. Predicted mortality was 22.9%; actual mortality was 15.7%. ...

journal_title：Cleveland Clinic journal of medicine

authors： Lockrem JD,Lopez E,Gallagher J,Church GE,Estafanous FG

更新日期：1991-11-01 00:00:00

abstract：:Obstructive sleep apnea (OSA) is a serious condition associated with impaired quality of life, depression, drowsy driving and motor vehicle accidents, metabolic disease, and cognitive decline. The mechanisms accounting for OSA and metabolic disease include hypoxia, sleep fragmentation, and systemic inflammation. OSA a...

journal_title：Cleveland Clinic journal of medicine

authors： Walia HK

更新日期：2019-09-01 00:00:00

abstract：:Many drugs can injure the kidneys, but they cause renal injury via only a few common mechanisms. Many patients who develop renal injury after drug exposure have identifiable risk factors that could be modified or that should preclude the use of these drugs in the first place. ...

journal_title：Cleveland Clinic journal of medicine

authors： Guo X,Nzerue C

更新日期：2002-04-01 00:00:00

abstract：:Primary care physicians must initiate a discussion of overactive bladder and urinary incontinence with their patients who are at risk. A stepwise approach to evaluation and diagnosis and the use of systematic evaluation and treatment algorithms suitable to the primary care setting will improve identification and effec...

journal_title：Cleveland Clinic journal of medicine

authors： Rosenberg MT,Dmochowski RR

更新日期：2005-02-01 00:00:00

abstract：:Evidence is mounting that depression is a risk factor for the development of cardiovascular disease and portends a worse outcome in cardiac patients. Depression can be easily diagnosed and safely treated in cardiac patients, but it is undertreated. ...

journal_title：Cleveland Clinic journal of medicine

authors： Kemp DE,Malhotra S,Franco KN,Tesar G,Bronson DL

更新日期：2003-09-01 00:00:00

abstract：:Annular pancreas is a congenital anomaly which, though present at birth, may cause few symptoms until adulthood. A case of annular pancreas with intermittent duodenal obstruction is described in a 49-year-old alcoholic man. Few other entities cause such obstruction. In similar cases, clinical suspicion of annular panc...

journal_title：Cleveland Clinic journal of medicine

authors： Sperrazza JC,Flanagan RA Jr,Katlic MR

更新日期：1992-03-01 00:00:00

abstract：:Pancreas transplantation can improve quality of life for patients with type 1 diabetes by eliminating hypoglycemic and hyperglycemic episodes, the need for insulin injections, frequent self-monitoring of blood glucose levels, and dietary restrictions. Increasing evidence suggests that it may slow the progression of lo...

journal_title：Cleveland Clinic journal of medicine

authors： Mayes JT,Dennis VW,Hoogwerf BJ

更新日期：2000-04-01 00:00:00

abstract：:The focus of palliative care is to alleviate pain and suffering for patients, potentially while they concurrently pursue life-prolonging or curative therapy. The potential breadth of palliative care is recognized by the Medicare program, but the Medicare hospice benefit is narrowly defined and limited to care that is ...

journal_title：Cleveland Clinic journal of medicine

authors： Labson MC,Sacco MM,Weissman DE,Gornet B,Stuart B

更新日期：2013-01-01 00:00:00

abstract：:In hospitalized medical patients, randomized trials have established that anticoagulant prophylaxis has an acceptable benefit-to-risk ratio: ie, it lowers the incidence of clinically silent and symptomatic venous thromboembolism (VTE), including fatal pulmonary embolism, more than it raises the risks of bleeding and o...

journal_title：Cleveland Clinic journal of medicine

authors： Pai M,Douketis JD

更新日期：2010-02-01 00:00:00

abstract：:Therapeutic hypothermia in acute resuscitation medicine has a long history, but its currently recommended use dates back to work in the mid-1960s by the late Dr. Peter Safar and colleagues. Compared with normothermia, mild therapeutic hypothermia, induced right after restoration of spontaneous circulation in comatose ...

journal_title：Cleveland Clinic journal of medicine

authors： Kochanek PM

更新日期：2009-04-01 00:00:00

abstract：:Obesity is epidemic and dangerous. Weight loss is difficult but worth the effort. Although new weight-loss drugs are available, there are no magic bullets: to lose weight and keep it off, people must eat less and exercise more. This article presents a practical approach on how physicians can help their patients lose w...

journal_title：Cleveland Clinic journal of medicine

authors： Weiss D

更新日期：2000-10-01 00:00:00

abstract：:Circadian variations have been observed for a number of hemodynamic and cardiovascular events including heart rate, systemic blood pressure, coronary artery blood flow, ischemic cerebrovascular accidents, myocardial ischemia, myocardial infarction, and sudden cardiac death. In addition, circadian variations in platele...

journal_title：Cleveland Clinic journal of medicine

authors： Becker RC,Corrao JM

更新日期：1989-10-01 00:00:00

abstract：:Blood tests are available that measure levels of immunoglobulin E (IgE) against specific allergens such as foods, inhalants, medications, latex, and venoms. These tests can confirm the diagnosis of an allergic disorder, supplementing a clinical history consistent with an immediate allergic reaction. They are particula...

journal_title：Cleveland Clinic journal of medicine

authors： Siles RI,Hsieh FH

更新日期：2011-09-01 00:00:00

abstract：:Hirsutism is a source of significant anxiety in women. While polycystic ovary syndrome or other endocrine conditions are responsible for excess androgen in many patients, other patients have normal menses and normal androgen levels ("idiopathic" hirsutism). The goal of the evaluation is to rule out any underlying path...

journal_title：Cleveland Clinic journal of medicine

authors： Harrison S,Somani N,Bergfeld WF

更新日期：2010-06-01 00:00:00