Preventing venous thromboembolism in long-term care residents: Cautious advice based on limited data.

abstract：:Nonspinal musculoskeletal disorders frequently cause neck and back pain and thus can mimic conditions of the spine. Common mimics are rotator cuff tears, bursitis in the hip, peripheral nerve compression, and arthritis in the shoulder and hip. A thorough history and physical examination, imaging studies, and ancillary...

journal_title：Cleveland Clinic journal of medicine

authors： Pateder DB,Brems J,Lieberman I,Bell GR,McLain RF

更新日期：2008-01-01 00:00:00

abstract：:Therapeutic hypothermia in acute resuscitation medicine has a long history, but its currently recommended use dates back to work in the mid-1960s by the late Dr. Peter Safar and colleagues. Compared with normothermia, mild therapeutic hypothermia, induced right after restoration of spontaneous circulation in comatose ...

journal_title：Cleveland Clinic journal of medicine

authors： Kochanek PM

更新日期：2009-04-01 00:00:00

abstract：:Fraud in scientific research is a widespread problem. It can involve falsifying data or documents, or knowingly failing to comply with regulations protecting research participants. Fraud can be committed by individuals, institutions, or corporations; in the context of research, fraud often is motivated by consideratio...

journal_title：Cleveland Clinic journal of medicine

authors： Sheehan JG

更新日期：2007-03-01 00:00:00

abstract：:Although stress-related mucosal damage is common (and potentially serious) in critically ill patients, the risk of clinically significant gastrointestinal bleeding appears to be confined to patients with certain factors: mechanical ventilation, coagulopathy, multiple trauma, increased intracranial pressure, and multio...

journal_title：Cleveland Clinic journal of medicine

authors： Bobek MB,Arroliga AC

更新日期：1997-11-01 00:00:00

abstract：:Decisions about whether and how long to treat seizures in children and adolescents should be based on rational criteria and knowledge of the natural history of epileptic syndromes, rather than on the presumption that all seizures should be treated at any cost. ...

journal_title：Cleveland Clinic journal of medicine

authors： Zacharowicz L,Moshé SL

更新日期：1995-05-01 00:00:00

abstract：:Much scientific and anecdotal data demonstrate favorable metabolic responses to very-low-carbohydrate diets. We believe that very-low-carbohydrate diets merit further study for weight loss, and that criticisms of these diets lack scientific evidence. ...

journal_title：Cleveland Clinic journal of medicine

authors： Volek JS,Westman EC

更新日期：2002-11-01 00:00:00

abstract：:Lifestyle modifications in conjunction with antidiabetes medications can produce near-normal blood glucose concentrations in patients with type 2 diabetes mellitus (T2DM). Because these patients have increased cardiovascular morbidity and mortality, treatment strategies should also address the cardiovascular aspects o...

journal_title：Cleveland Clinic journal of medicine

authors： Peters AL

更新日期：2009-12-01 00:00:00

abstract：:Mild cognitive impairment (MCI) is a common heterogeneous syndrome that in some cases is transitional between normal age-related cognitive changes and dementia. Identifying it early may lead to prompt recognition of reversible causes and allows for timely future planning. This article describes definitions of MCI and ...

journal_title：Cleveland Clinic journal of medicine

authors： Patel BB,Holland NW

更新日期：2012-12-01 00:00:00

abstract：:Pancreas transplantation can improve quality of life for patients with type 1 diabetes by eliminating hypoglycemic and hyperglycemic episodes, the need for insulin injections, frequent self-monitoring of blood glucose levels, and dietary restrictions. Increasing evidence suggests that it may slow the progression of lo...

journal_title：Cleveland Clinic journal of medicine

authors： Mayes JT,Dennis VW,Hoogwerf BJ

更新日期：2000-04-01 00:00:00

abstract：:Heart failure is the most important public health problem in cardiovascular medicine, and is increasing in both prevalence and expense. Programs that use an interdisciplinary team to improve outpatient treatment and prevent hospitalizations will help improve care and control costs. But the most important long-term str...

journal_title：Cleveland Clinic journal of medicine

authors： Starling RC

更新日期：1998-07-01 00:00:00

abstract：:Cyclospora cayetanensis, an emerging pathogen with worldwide distribution, causes diarrhea in both immunocompetent and HIV-infected patients. We review the epidemiology of Cyclospora infection and how to diagnose and treat it. ...

journal_title：Cleveland Clinic journal of medicine

authors： Gumbo T,Gordon SM,Adal KA

更新日期：1997-06-01 00:00:00

abstract：:Patients with systemic lupus erythematosus (SLE, lupus) have a markedly better survival rate today than they did 50 years ago, but they face a greater risk of cancer, cardiovascular disease, and osteoporosis at early ages. With better understanding of the immunological mechanisms of the disease, new avenues of therapy...

journal_title：Cleveland Clinic journal of medicine

authors： Manzi S

更新日期：2009-02-01 00:00:00

abstract：:Women with heart failure differ from their male counterparts in a number of ways, including etiology, pattern of cardiac remodeling, and prognosis. They may even respond differently to medical therapy. But until prospective, sex-specific studies show that we should do otherwise, we recommend that women with heart fail...

journal_title：Cleveland Clinic journal of medicine

authors： Mezu U,Bott-Silverman C,Hsich E

更新日期：2007-06-01 00:00:00

abstract：:The American Heart Association issued a science advisory on depression and coronary heart disease (CHD) in 2008. This paper reviews the purpose and content of the advisory and discusses reactions and new information that have followed the advisory's release. Both the advisory and subsequent data support routine screen...

journal_title：Cleveland Clinic journal of medicine

authors： Bigger JT,Glassman AH

更新日期：2010-07-01 00:00:00

abstract：:The aromatase inhibitors are established first-line drugs for treating metastatic breast cancer in postmenopausal women, and are gaining acceptance as adjuvant treatment as well. ...

journal_title：Cleveland Clinic journal of medicine

authors： Hill J,Moore H

更新日期：2002-07-01 00:00:00

abstract：:Both diabetic and prediabetic patients have abnormal vascular reactivity and should be considered to have occult cardiovascular disease. Angiotensin-converting-enzyme (ACE) inhibitors are particularly beneficial in diabetes because they reduce the incidence of both cardiovascular events and diabetes-related complicati...

journal_title：Cleveland Clinic journal of medicine

authors： Hsueh WA

更新日期：2000-11-01 00:00:00

abstract：:Morbidity and mortality rates of human immunodeficiency virus (HIV) have plummeted where highly active antiretroviral therapy (HAART) is available. However, therapy is out of reach for most people who need it in developing nations, where the infrastructure to deliver care and resources for medications is lacking. Worl...

journal_title：Cleveland Clinic journal of medicine

authors： Armstrong W,Calabrese L,Taege AJ

更新日期：2005-01-01 00:00:00

abstract：:Annular pancreas is a congenital anomaly which, though present at birth, may cause few symptoms until adulthood. A case of annular pancreas with intermittent duodenal obstruction is described in a 49-year-old alcoholic man. Few other entities cause such obstruction. In similar cases, clinical suspicion of annular panc...

journal_title：Cleveland Clinic journal of medicine

authors： Sperrazza JC,Flanagan RA Jr,Katlic MR

更新日期：1992-03-01 00:00:00

abstract：:Special problems of Asian patients have considerable impact on diagnosis and treatment, and the number of persons of Asian ancestry seen in primary care in the United States is increasing. Knowledge of how to provide optimal care despite language barriers, low socioeconomic status, different health beliefs and practic...

journal_title：Cleveland Clinic journal of medicine

authors： Jin XW,Slomka J,Blixen CE

更新日期：2002-01-01 00:00:00

abstract：:Although there is still no consensus on how to diagnose hypertension, opinion is moving toward incorporating out-of-office blood pressure measurements into the process. The SPRINT trial poses potential opportunities and challenges. Simplified antihypertensive drug regimens incorporating single pill combinations are ve...

journal_title：Cleveland Clinic journal of medicine

authors： Handler J

更新日期：2015-12-01 00:00:00

abstract：:Informed consent in clinical research is a matter of both ethics and federal regulation. A research subject must enter a study voluntarily, be informed about risks and benefits, and understand the difference between experiment and treatment. ...

journal_title：Cleveland Clinic journal of medicine

authors： Bramstedt KA

更新日期：2004-11-01 00:00:00

abstract：:Because type 2 diabetes mellitus is a progressive disease, most patients eventually need insulin. When and how to start insulin therapy are not one-size-fits-all decisions but rather must be individualized. This paper reviews the indications, goals, and options for insulin therapy in type 2 diabetes. ...

journal_title：Cleveland Clinic journal of medicine

authors： Brateanu A,Russo-Alvarez G,Nielsen C

更新日期：2015-08-01 00:00:00

abstract：:Obsessive-compulsive disorder (OCD) is the fourth most common psychiatric disorder. Yet patients often avoid seeking help because they are ashamed. Diagnosis is difficult, but familiarity with the nature of OCD and its current management helps primary care physicians identify patients with OCD and make informed judgme...

journal_title：Cleveland Clinic journal of medicine

authors： El-Sayegh S,Bea S,Agelopoulos A

更新日期：2003-10-01 00:00:00

abstract：:An increasing array of treatments such as immunosuppressive drugs and tumor necrosis factor inhibitors can offer patients with ulcerative colitis and Crohn disease improved relief from symptoms with fewer adverse effects. Several additional drugs have shown promise, including nicotine, antimicrobials, and heparin. ...

journal_title：Cleveland Clinic journal of medicine

authors： Wolf JM,Lashner BA

更新日期：2002-08-01 00:00:00

abstract：:Many effective treatments for scleroderma have emerged in recent years, including bosentan, an endothelin receptor antagonist, and epoprostenol, a prostacyclin, both of which target vasoconstriction. Cyclophosphamide may soon be proven effective against interstitial lung disease. ...

journal_title：Cleveland Clinic journal of medicine

authors： Korn JH

更新日期：2003-11-01 00:00:00

abstract：:Despite the availability of highly active antiretroviral therapy (HAART) for the treatment of human immunodeficiency virus (HIV) infection, there has not been a dramatic decrease in the frequency of progressive multifocal leukoencephalopathy (PML) in the HIV-infected population. Usually a multifocal progressive diseas...

journal_title：Cleveland Clinic journal of medicine

authors： Simpson DM

更新日期：2011-11-01 00:00:00

abstract：:Obstructive sleep apnea (OSA) is a serious condition associated with impaired quality of life, depression, drowsy driving and motor vehicle accidents, metabolic disease, and cognitive decline. The mechanisms accounting for OSA and metabolic disease include hypoxia, sleep fragmentation, and systemic inflammation. OSA a...

journal_title：Cleveland Clinic journal of medicine

authors： Walia HK

更新日期：2019-09-01 00:00:00

abstract：:Severe acute pancreatitis causes high rates of illness and death. Simple scoring predictors can help identify patients at risk so that treatment, primarily supportive, can begin promptly after presentation. Medical therapy is the mainstay, with supportive therapy consisting of controlled volume resuscitation and enter...

journal_title：Cleveland Clinic journal of medicine

authors： Baron TH

更新日期：2013-06-01 00:00:00

abstract：:Women infected with human immunodeficiency virus (HIV) have unique needs. Treatment recommendations are the same for men and women, but in women, fertility desires, pregnancy, contraception, and aging must be taken into account in their medical care. ...

journal_title：Cleveland Clinic journal of medicine

authors： Short WR,Anderson JR

更新日期：2014-11-01 00:00:00

abstract：:In patients with long-standing, poorly controlled diabetes and peripheral neuropathy, a red, hot, swollen foot without open ulceration should raise the suspicion of Charcot neuroarthropathy, an often-overlooked diabetic foot complication. The authors discuss key diagnostic features and how to differentiate this condit...

journal_title：Cleveland Clinic journal of medicine

authors： Botek G,Anderson MA,Taylor R

更新日期：2010-09-01 00:00:00