In diabetes, treat hidden heart disease.

abstract：:Although atrial fibrillation is well tolerated by most patients, in some patients the consequences may be severe. The Maze procedure is a new open-heart operation that creates a carefully designed maze of incisions in the atrial myocardium; this maze then acts as an electrical conduit to channel atrial impulses from t...

journal_title：Cleveland Clinic journal of medicine

authors： McCarthy PM,Castle LW,Trohman RG,Simmons TW,Maloney JD,Klein AL,White RD,Cox JL

更新日期：1993-03-01 00:00:00

abstract：:The importance of glycemic control in preventing the chronic and devastating complications of diabetes is well established. Insulin administration is an important therapeutic option for managing diabetes, particularly for patients with profound insulin deficiency. Many insulin formulations are on the market, including...

journal_title：Cleveland Clinic journal of medicine

authors： Meneghini L

更新日期：2016-05-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is an important cause of death in patients with liver disease, and its incidence appears to be rising in the United States. Because early diagnosis improves the chances of survival, it is important to identify patients who would benefit from surveillance. Once HCC is suspected on surveil...

journal_title：Cleveland Clinic journal of medicine

authors： Murali AR,Romero-Marrero C,Aucejo F,Menon KV

更新日期：2013-10-01 00:00:00

abstract：:Patients with pulmonary arterial hypertension (PAH) may present to internists, rheumatologists, cardiologists, or pulmonologists. This breadth of clinicians who encounter PAH patients, together with the complicated nature of PAH as a disease entity, argues for a shared-care approach to the management of these patients...

journal_title：Cleveland Clinic journal of medicine

authors： Mughal MM,Mandell B,James K,Stelmach K,Minai OA

更新日期：2003-04-01 00:00:00

abstract：:When a patient reports constipation, a careful history and physical examination may identify the underlying cause. In many patients, though, no underlying cause is identified. Empiric treatment with exercise, hydration, fiber supplementation, and mild laxatives is often effective. If constipation does not resolve with...

journal_title：Cleveland Clinic journal of medicine

authors： Soffer EE

更新日期：1999-01-01 00:00:00

abstract：:Too often, physicians, patients, and families make end-of-life care decisions despite poor physician-patient communication and misunderstanding by the patient and family about the effectiveness of cardiopulmonary resuscitation. We describe an approach to resolving conflict and reaching consensus on end-of-life care. T...

journal_title：Cleveland Clinic journal of medicine

authors： Agich GJ,Arroliga AC

更新日期：2000-06-01 00:00:00

abstract：:Heart failure is the most important public health problem in cardiovascular medicine, and is increasing in both prevalence and expense. Programs that use an interdisciplinary team to improve outpatient treatment and prevent hospitalizations will help improve care and control costs. But the most important long-term str...

journal_title：Cleveland Clinic journal of medicine

authors： Starling RC

更新日期：1998-07-01 00:00:00

abstract：:Despite the availability of highly active antiretroviral therapy (HAART) for the treatment of human immunodeficiency virus (HIV) infection, there has not been a dramatic decrease in the frequency of progressive multifocal leukoencephalopathy (PML) in the HIV-infected population. Usually a multifocal progressive diseas...

journal_title：Cleveland Clinic journal of medicine

authors： Simpson DM

更新日期：2011-11-01 00:00:00

abstract：:Vascular surgery is associated with a high risk of perioperative morbidity and mortality that is partly attributable to inflammatory stress induced by the surgical procedure. Preoperative initiation of a long-acting statin is a strategy intended to reduce the inflammatory stress response and the excess risk associated...

journal_title：Cleveland Clinic journal of medicine

authors： Poldermans D

更新日期：2009-11-01 00:00:00

abstract：:One of the most important deficiency states associated with chronic renal failure is profound anemia. While it has been possible to identify differing types of anemia in patients receiving dialysis support, and thus correct the secondary causes, most patients continue to exhibit symptoms and signs of the anemic state....

journal_title：Cleveland Clinic journal of medicine

authors： Paganini EP,Garcia J,Abdulhadi M,Lathim D,Giesman J,Weick JK

更新日期：1989-01-01 00:00:00

abstract：:Tailored care will increasingly become the hallmark of treatment for patients with hypertension in the 1990s. In mildly hypertensive patients, treatment should begin with nonpharmacologic approaches to lower blood pressure and reduce the patient's cardiovascular risk profile. The ever-increasing array of antihypertens...

journal_title：Cleveland Clinic journal of medicine

authors： Vidt DG

更新日期：1991-05-01 00:00:00

abstract：:The aromatase inhibitors are established first-line drugs for treating metastatic breast cancer in postmenopausal women, and are gaining acceptance as adjuvant treatment as well. ...

journal_title：Cleveland Clinic journal of medicine

authors： Hill J,Moore H

更新日期：2002-07-01 00:00:00

abstract：:Deep brain stimulation (DBS) is among the most effective approaches for the treatment of patients with advanced movement disorders. In patients with essential tremor, stimulation typically targets the ventral intermediate nucleus of the thalamus. Results of several studies have shown that over a follow-up period of 1 ...

journal_title：Cleveland Clinic journal of medicine

authors： Cooper S,Bowes M

更新日期：2012-07-01 00:00:00

abstract：:Coronary artery disease is different in women than in men in its pathogenesis, symptoms, and prognosis. Needed is a strategy for detecting and assessing coronary disease specifically in women. This review highlights recent evidence on sex differences in coronary artery disease. ...

journal_title：Cleveland Clinic journal of medicine

authors： Bellasi A,Raggi P,Merz CN,Shaw LJ

更新日期：2007-08-01 00:00:00

abstract：:An immunocompromised patient presented with chronic low back pain as the initial symptom and a subcutaneous abscess as the initial sign of disseminated aspergillosis. With the rising incidence of immunocompromised patients, cutaneous manifestation of aspergillosis may become more common. ...

journal_title：Cleveland Clinic journal of medicine

authors： Helm TN,Mazanec D

更新日期：1990-01-01 00:00:00

abstract：:Thirty-four young patients (28 male and 6 female) underwent aortic valve replacement between 1972 and 1988. Ages ranged from 11 to 20 years (mean 17.7 years). Including reimplantation in the follow-up period, 40 valves were implanted, among which were 17 (43%) St. Jude, 7 (16%) Bjork-Shiley, and 4 (10%) Carpentier-Edw...

journal_title：Cleveland Clinic journal of medicine

authors： Moodie DS,Hanhan U,Sterba R,Murphy DJ Jr,Rosenkranz ER,Kovacs AM

更新日期：1992-09-01 00:00:00

abstract：:A surprising number of apparently healthy people harbor unsuspected pituitary tumors, which are being discovered incidentally on computed tomography (CT) or magnetic resonance imaging (MRI) performed for other reasons. The majority can be safely observed; for others, medical therapy or surgical resection is necessary....

journal_title：Cleveland Clinic journal of medicine

authors： Serhal D,Weil RJ,Hamrahian AH

更新日期：2008-11-01 00:00:00

abstract：:Studies published during the past year on the treatment of several infectious diseases provide valuable information that should enable us to treat our patients more effectively. Among those findings: Oral vancomycin (Vancocin) is superior to oral metronidazole (Flagyl) for treating patients with severe Clostridium dif...

journal_title：Cleveland Clinic journal of medicine

authors： Longworth DL

更新日期：2008-08-01 00:00:00

abstract：:Although the literature is limited, early evidence suggests that patients with chronic kidney disease, end-stage kidney disease, and kidney transplant recipients are at increased risk for severe COVID-19 disease and death. Hence, management should focus on both infection prevention and treatment. There is currently a ...

journal_title：Cleveland Clinic journal of medicine

authors： Radhakrishnan Y,Hassanein M,Stephany B

更新日期：2020-12-03 00:00:00

abstract：:Therapeutic hypothermia in acute resuscitation medicine has a long history, but its currently recommended use dates back to work in the mid-1960s by the late Dr. Peter Safar and colleagues. Compared with normothermia, mild therapeutic hypothermia, induced right after restoration of spontaneous circulation in comatose ...

journal_title：Cleveland Clinic journal of medicine

authors： Kochanek PM

更新日期：2009-04-01 00:00:00

abstract：:In hospitalized medical patients, randomized trials have established that anticoagulant prophylaxis has an acceptable benefit-to-risk ratio: ie, it lowers the incidence of clinically silent and symptomatic venous thromboembolism (VTE), including fatal pulmonary embolism, more than it raises the risks of bleeding and o...

journal_title：Cleveland Clinic journal of medicine

authors： Pai M,Douketis JD

更新日期：2010-02-01 00:00:00

abstract：:We reviewed the population of a surgical intensive care unit from July 1, 1987 to June 30, 1988, adjusting for severity of illness using the APACHE II system. Nineteen different departments admitted a total of 613 patients to the surgical intensive care unit. Predicted mortality was 22.9%; actual mortality was 15.7%. ...

journal_title：Cleveland Clinic journal of medicine

authors： Lockrem JD,Lopez E,Gallagher J,Church GE,Estafanous FG

更新日期：1991-11-01 00:00:00

abstract：:Interleukin 1 (IL-1) is a potential target of therapy in COVID-19 during the severe respiratory-inflammatory phase ("cytokine release syndrome"), when pulmonary macrophages are hyperactivated, releasing IL-1 and other cytokines. Preliminary evidence indicates that anakinra and canakinumab, drugs that block the action ...

journal_title：Cleveland Clinic journal of medicine

authors： Calabrese LH,Calabrese C

更新日期：2020-07-09 00:00:00

abstract：:Behavioral disorders in pediatric patients--primarily attention deficit hyperactivity disorder (ADHD)--pose a clinical challenge for health care providers to accurately assess, diagnose, and treat. In 2013, updated diagnostic criteria for behavioral disorders were published, including ADHD and a new diagnostic entity:...

journal_title：Cleveland Clinic journal of medicine

authors： Austerman J

更新日期：2015-11-01 00:00:00

abstract：:Treatment of anemia in the perioperative period of major orthopedic surgery decreases the need for blood transfusion and improves perioperative outcomes. Use of epoetin alfa in this setting is FDA-approved and provides significant benefit to qualified and carefully chosen patients. ...

journal_title：Cleveland Clinic journal of medicine

authors： Kumar A,Dimov V

更新日期：2006-09-01 00:00:00

abstract：:Mild cognitive impairment (MCI) is a common heterogeneous syndrome that in some cases is transitional between normal age-related cognitive changes and dementia. Identifying it early may lead to prompt recognition of reversible causes and allows for timely future planning. This article describes definitions of MCI and ...

journal_title：Cleveland Clinic journal of medicine

authors： Patel BB,Holland NW

更新日期：2012-12-01 00:00:00

abstract：:SCS is an efficacious, reversible, and safe therapy that improves quality of life, increases exercise tolerance, and relieves angina pectoris, but clinical trials in North America are needed to confirm the data coming from Europe. Neuronal convergence onto STT cells underlies the referred pain associated with angina p...

journal_title：Cleveland Clinic journal of medicine

authors： Foreman RD

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Nicotinic acid, widely used to lower serum cholesterol levels, may rarely cause cholestatic jaundice. SUMMARY:A 61-year-old white man with hypercholesterolemia complained of marked pruritus and became jaundiced after taking 3.0 g of crystalline nicotinic acid daily for 13 months. His total serum bilirubin l...

journal_title：Cleveland Clinic journal of medicine

authors： Patel SD,Taylor HC

更新日期：1994-01-01 00:00:00

abstract：:Many drugs can injure the kidneys, but they cause renal injury via only a few common mechanisms. Many patients who develop renal injury after drug exposure have identifiable risk factors that could be modified or that should preclude the use of these drugs in the first place. ...

journal_title：Cleveland Clinic journal of medicine

authors： Guo X,Nzerue C

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Mediastinal extension of pancreatic pseudocysts has caused rare cases of cardiac compression, but to our knowledge, congestive heart disease due to cardiac compression by a pancreatic pseudocyst has never been reported. SUMMARY:A 48-year-old man presented with dyspnea, swelling of both lower limbs, left-sid...

journal_title：Cleveland Clinic journal of medicine

authors： Lee FY,Wang YT,Poh SC

更新日期：1994-03-01 00:00:00