The practical management of gout.

Abstract:

:Gout management requires a comprehensive strategy that considers both acute and chronic aspects of the disease. Acute gout flares should be treated with anti-inflammatory agents as rapidly as possible. The underlying hyperuricemia may be treated with urate-lowering agents initiated at a time appropriate for the individual patient. Successful urate lowering ultimately prevents flares and disease progression and should be started immediately in patients with advanced or tophaceous disease. When urate-lowering therapy is initiated, anti-inflammatory prophylaxis should be used to reduce the risk of flares induced by abrupt changes in urate levels. Regular monitoring of serum urate can ensure therapeutic dosing of urate-lowering agents to achieve levels below 6 mg/dL, which are associated with a reduction in flares and tophi.

journal_name

Cleve Clin J Med

authors

Schumacher HR Jr,Chen LX

doi

10.3949/ccjm.75.suppl_5.s22

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

S22-5

eissn

0891-1150

issn

1939-2869

journal_volume

75 Suppl 5

pub_type

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