Treatment of psoriasis with chronic subcutaneous administration of somatostatin analog 201-995 (sandostatin). I. An open-label pilot study.

abstract：:Recent studies have significantly broadened understanding of immunoglobulin production and T-cell receptor formation at the gene level. A limited number of genes can be rearranged during the course of B-cell or T-cell development to yield unique DNA sequences that will code for specific antibodies and T-cell receptor ...

journal_title：Cleveland Clinic journal of medicine

authors： Fishleder AJ

更新日期：1989-10-01 00:00:00

abstract：:SCS is an efficacious, reversible, and safe therapy that improves quality of life, increases exercise tolerance, and relieves angina pectoris, but clinical trials in North America are needed to confirm the data coming from Europe. Neuronal convergence onto STT cells underlies the referred pain associated with angina p...

journal_title：Cleveland Clinic journal of medicine

authors： Foreman RD

更新日期：2007-02-01 00:00:00

abstract：:Eating disorders are common in adolescents and young adults, including those with a history of overweight or obesity, and are associated with numerous systemic sequelae. Understanding the differences in presentation between these patients and those who have a more classic anorexia nervosa phenotype is critical to ensu...

journal_title：Cleveland Clinic journal of medicine

authors： Rastogi R,Rome Md ES

更新日期：2020-03-01 00:00:00

abstract：:Elderly patients pose unique challenges perioperatively. They are more likely than younger surgical patients to be mentally and physically compromised at baseline, which increases the risk of delirium and postoperative cognitive dysfunction. Postoperative cognitive risk can be predicted, however, and effective strateg...

journal_title：Cleveland Clinic journal of medicine

authors： Palmer RM

更新日期：2009-11-01 00:00:00

abstract：:In cases of low back pain, the goal is to detect serious problems and to prevent the pain from becoming chronic by promptly detecting risk factors. The authors lay out a simple, evidence-based approach to low back pain. ...

journal_title：Cleveland Clinic journal of medicine

authors： Bhangle SD,Sapru S,Panush RS

更新日期：2009-07-01 00:00:00

abstract：:Often patients with immune hemolytic anemias present with symptoms that are common in anemia of any cause. In the different types of immune hemolytic anemia, red blood cells are destroyed by processes mediated by antibodies. This article reviews the pathophysiology, diagnosis, and treatment of this group of diseases. ...

journal_title：Cleveland Clinic journal of medicine

authors： Domen RE

更新日期：1998-02-01 00:00:00

abstract：:The most important component of the treatment of irritable bowel syndrome (IBS) is to establish a therapeutic physician-patient relationship, coupled with patient education. We describe a stepwise approach to management, including judicious use of invasive tests, and setting realistic treatment goals that address the ...

journal_title：Cleveland Clinic journal of medicine

authors： Shen B,Soffer E

更新日期：2001-03-01 00:00:00

abstract：:Morbidity and mortality rates of human immunodeficiency virus (HIV) have plummeted where highly active antiretroviral therapy (HAART) is available. However, therapy is out of reach for most people who need it in developing nations, where the infrastructure to deliver care and resources for medications is lacking. Worl...

journal_title：Cleveland Clinic journal of medicine

authors： Armstrong W,Calabrese L,Taege AJ

更新日期：2005-01-01 00:00:00

abstract：:A case of pacemaker lead dysfunction with subsequent removal by a unique transvenous extraction system is presented. This technique allows detailed examination of the extracted pacemaker lead and identification of unsuspected causes of lead failure. Information relative to specific causes of lead failure may result in...

journal_title：Cleveland Clinic journal of medicine

authors： Brodell GK,Wilkoff BL

更新日期：1992-01-01 00:00:00

abstract：:Biochemical markers of bone turnover provide clinically useful evidence of the normal and pathologic processes that reflect bone cell activity in the skeleton. Understanding the behavior of markers of bone formation and bone resorption should aid in managing patients with a variety of skeletal disorders. ...

journal_title：Cleveland Clinic journal of medicine

authors： Singer FR,Eyre DR

更新日期：2008-10-01 00:00:00

abstract：:A patient with progressive psoriatic arthritis refractory to methotrexate therapy was treated empirically with intravenous nitrogen mustard, or HN2. His response to therapy was compared with the responses of five rheumatoid arthritis patients treated with the same regimen. At 14 days after therapy was begun the patien...

journal_title：Cleveland Clinic journal of medicine

authors： Wilke WS,Sexton C,Steck W

更新日期：1990-10-01 00:00:00

abstract：:Although atrial fibrillation is well tolerated by most patients, in some patients the consequences may be severe. The Maze procedure is a new open-heart operation that creates a carefully designed maze of incisions in the atrial myocardium; this maze then acts as an electrical conduit to channel atrial impulses from t...

journal_title：Cleveland Clinic journal of medicine

authors： McCarthy PM,Castle LW,Trohman RG,Simmons TW,Maloney JD,Klein AL,White RD,Cox JL

更新日期：1993-03-01 00:00:00

abstract：:Exercise, in conjunction with diet, is critical to losing weight and maintaining health in obese patients. While it can be challenging for an obese person to transition to a healthy lifestyle, the physical and emotional benefits of a regular exercise program make it worth the effort. ...

journal_title：Cleveland Clinic journal of medicine

authors： Higgins JP,Higgins CL

更新日期：2016-02-01 00:00:00

abstract：:Clinicians are bombarded with information daily by social media, mainstream television news, e-mail, and print and online reports. They usually do not have much control over these information streams and thus are passive recipients, which means they get more noise than signal. Accessing, absorbing, organizing, storing...

journal_title：Cleveland Clinic journal of medicine

authors： Mehta NB,Martin SA,Maypole J,Andrews R

更新日期：2016-08-01 00:00:00

abstract：:Nephrotic syndrome can now be treated effectively in most cases. All patients should be treated with a low-salt diet, diuretics to reduce edema, and statins to normalize serum lipid concentrations. Patients with nephrotic syndrome are prone to deep vein thrombophlebitis, renal vein thrombosis, and pulmonary emboli. De...

journal_title：Cleveland Clinic journal of medicine

authors： Appel GB

更新日期：2006-02-01 00:00:00

abstract：:A case is reported of lambda light chain multiple myeloma complicated by a myelomatous pleural effusion. Pleural effusions are uncommon in multiple myeloma, and most are secondary to nonmalignant causes. The clinical characteristics, natural history and pathophysiology of myelomatous pleural effusions are reviewed. ...

journal_title：Cleveland Clinic journal of medicine

authors： Abbate SL,Jaff MR,Fishleder AJ,Meeker DP

更新日期：1991-05-01 00:00:00

abstract：:In the article "Quitting smoking: Still a challenge, but newer tools show promise," (Collins GB, Jerry JM, Bales R. Cleve Clin J Med 2015; 82:39-48), the reference sequencing has been corrected. ...

journal_title：Cleveland Clinic journal of medicine

authors： Collins GB,Jerry JM,Bales R

更新日期：2015-02-01 00:00:00

abstract：:Epidemiologic and experimental data suggest that isoflavones have benefits for preventing and treating some prostate disease. Isoflavone supplements may therefore be an important tool for men concerned about prostate disease, such as those with benign prostatic hypertrophy undergoing watchful waiting or those concerne...

journal_title：Cleveland Clinic journal of medicine

authors： Gaynor ML

更新日期：2003-03-01 00:00:00

abstract：:The aromatase inhibitors are established first-line drugs for treating metastatic breast cancer in postmenopausal women, and are gaining acceptance as adjuvant treatment as well. ...

journal_title：Cleveland Clinic journal of medicine

authors： Hill J,Moore H

更新日期：2002-07-01 00:00:00

abstract：:Lifestyle factors remain the bedrock of atherosclerotic cardiovascular disease (ASCVD) prevention. Statins remain the first-line therapy for primary and secondary prevention of ASCVD. Physicians are encouraged to discuss the risks and benefits of statins with patients before beginning therapy. Nonstatins and proprotei...

journal_title：Cleveland Clinic journal of medicine

authors： Cho L

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Mediastinal extension of pancreatic pseudocysts has caused rare cases of cardiac compression, but to our knowledge, congestive heart disease due to cardiac compression by a pancreatic pseudocyst has never been reported. SUMMARY:A 48-year-old man presented with dyspnea, swelling of both lower limbs, left-sid...

journal_title：Cleveland Clinic journal of medicine

authors： Lee FY,Wang YT,Poh SC

更新日期：1994-03-01 00:00:00

abstract：:The American Heart Association issued a science advisory on depression and coronary heart disease (CHD) in 2008. This paper reviews the purpose and content of the advisory and discusses reactions and new information that have followed the advisory's release. Both the advisory and subsequent data support routine screen...

journal_title：Cleveland Clinic journal of medicine

authors： Bigger JT,Glassman AH

更新日期：2010-07-01 00:00:00

abstract：:Obesity is a potent risk factor for the development and progression of type 2 diabetes, and weight loss is a key component of diabetes management. Bariatric surgery results in significant weight loss and remission of diabetes in most patients. After surgery, glycemic control is restored by a combination of enforced ca...

journal_title：Cleveland Clinic journal of medicine

authors： Kashyap SR,Gatmaitan P,Brethauer S,Schauer P

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Nicotinic acid, widely used to lower serum cholesterol levels, may rarely cause cholestatic jaundice. SUMMARY:A 61-year-old white man with hypercholesterolemia complained of marked pruritus and became jaundiced after taking 3.0 g of crystalline nicotinic acid daily for 13 months. His total serum bilirubin l...

journal_title：Cleveland Clinic journal of medicine

authors： Patel SD,Taylor HC

更新日期：1994-01-01 00:00:00

abstract：:Women with heart failure differ from their male counterparts in a number of ways, including etiology, pattern of cardiac remodeling, and prognosis. They may even respond differently to medical therapy. But until prospective, sex-specific studies show that we should do otherwise, we recommend that women with heart fail...

journal_title：Cleveland Clinic journal of medicine

authors： Mezu U,Bott-Silverman C,Hsich E

更新日期：2007-06-01 00:00:00

abstract：:Women infected with human immunodeficiency virus (HIV) have unique needs. Treatment recommendations are the same for men and women, but in women, fertility desires, pregnancy, contraception, and aging must be taken into account in their medical care. ...

journal_title：Cleveland Clinic journal of medicine

authors： Short WR,Anderson JR

更新日期：2014-11-01 00:00:00

abstract：:One of the most important deficiency states associated with chronic renal failure is profound anemia. While it has been possible to identify differing types of anemia in patients receiving dialysis support, and thus correct the secondary causes, most patients continue to exhibit symptoms and signs of the anemic state....

journal_title：Cleveland Clinic journal of medicine

authors： Paganini EP,Garcia J,Abdulhadi M,Lathim D,Giesman J,Weick JK

更新日期：1989-01-01 00:00:00

abstract：:An increasing array of treatments such as immunosuppressive drugs and tumor necrosis factor inhibitors can offer patients with ulcerative colitis and Crohn disease improved relief from symptoms with fewer adverse effects. Several additional drugs have shown promise, including nicotine, antimicrobials, and heparin. ...

journal_title：Cleveland Clinic journal of medicine

authors： Wolf JM,Lashner BA

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:There are now more than 31 million people 65 years of age or older in the United States, at least half of whom have systolic blood pressure 140 mm Hg or higher or diastolic blood pressure 90 mm Hg or higher or both. By the year 2050, 16 million Americans will be over age 85. OBJECTIVE:To review the current ...

journal_title：Cleveland Clinic journal of medicine

authors： Gifford RW Jr

更新日期：1995-01-01 00:00:00

abstract：:Several studies have documented that hypercholesterolemia is common in American children. Other studies have shown that elevated cholesterol levels in childhood remain elevated well into adult life. Autopsy studies of adolescents have also found a strong positive correlation between antemortem cholesterol levels and e...

journal_title：Cleveland Clinic journal of medicine

authors： Garcia RE,Moodie DS

更新日期：1990-11-01 00:00:00