Why and how to prescribe exercise: overcoming the barriers.

abstract：:Obesity is epidemic and dangerous. Weight loss is difficult but worth the effort. Although new weight-loss drugs are available, there are no magic bullets: to lose weight and keep it off, people must eat less and exercise more. This article presents a practical approach on how physicians can help their patients lose w...

journal_title：Cleveland Clinic journal of medicine

authors： Weiss D

更新日期：2000-10-01 00:00:00

abstract：:Many drugs can injure the kidneys, but they cause renal injury via only a few common mechanisms. Many patients who develop renal injury after drug exposure have identifiable risk factors that could be modified or that should preclude the use of these drugs in the first place. ...

journal_title：Cleveland Clinic journal of medicine

authors： Guo X,Nzerue C

更新日期：2002-04-01 00:00:00

abstract：:Paget disease of bone is a focal disorder of aging bone that may be asymptomatic or may present with pain, bowing deformity, fracture, or a nonspecific rheumatic complaint. It is the second most common disease of bone in the elderly after osteoporosis, and the loss of structural integrity in affected bone conveys a ri...

journal_title：Cleveland Clinic journal of medicine

authors： Seton M

更新日期：2013-07-01 00:00:00

abstract：:Obesity is associated with higher rates of death due to cancer. Possible explanations for this association include physiological factors associated with obesity, lower cancer screening rates in obese people, and technical difficulties in treating obese patients. These problems represent opportunities to improve the ca...

journal_title：Cleveland Clinic journal of medicine

authors： Bordeaux BC,Bolen S,Brotman DJ

更新日期：2006-10-01 00:00:00

abstract：:Patients with refractory epilepsy face an elevated risk of sudden death, with rates as high as 1% per year. This phenomenon, known as sudden unexpected death in epilepsy (SUDEP), is believed to be a seizure-related occurrence, but the exact underlying mechanisms are uncertain. Both pulmonary and cardiac pathophysiolog...

journal_title：Cleveland Clinic journal of medicine

authors： Jehi L,Najm IM

更新日期：2008-03-01 00:00:00

abstract：:Primary care physicians must initiate a discussion of overactive bladder and urinary incontinence with their patients who are at risk. A stepwise approach to evaluation and diagnosis and the use of systematic evaluation and treatment algorithms suitable to the primary care setting will improve identification and effec...

journal_title：Cleveland Clinic journal of medicine

authors： Rosenberg MT,Dmochowski RR

更新日期：2005-02-01 00:00:00

abstract：:SCS is an efficacious, reversible, and safe therapy that improves quality of life, increases exercise tolerance, and relieves angina pectoris, but clinical trials in North America are needed to confirm the data coming from Europe. Neuronal convergence onto STT cells underlies the referred pain associated with angina p...

journal_title：Cleveland Clinic journal of medicine

authors： Foreman RD

更新日期：2007-02-01 00:00:00

abstract：:Studies published during the past year on the treatment of several infectious diseases provide valuable information that should enable us to treat our patients more effectively. Among those findings: Oral vancomycin (Vancocin) is superior to oral metronidazole (Flagyl) for treating patients with severe Clostridium dif...

journal_title：Cleveland Clinic journal of medicine

authors： Longworth DL

更新日期：2008-08-01 00:00:00

abstract：:Infection with human immunodeficiency virus (HIV), hepatitis B virus (HBV), or hepatitis C virus (HCV) can cause rapidly progressive renal disease, so prompt recognition and management are critical. Viral glomerulonephropathy can now often be successfully managed with a specific combination of antiviral therapy, immun...

journal_title：Cleveland Clinic journal of medicine

authors： Appel G

更新日期：2007-05-01 00:00:00

abstract：:Cholesterol is a fat-like substance that is in our blood. Our bodies naturally produce some cholesterol. The other portion comes from animal products such as meat, eggs, butter, cheese, and whole milk. Foods from plants do no contain cholesterol. When you have a high level of cholesterol in your blood, it builds up in...

journal_title：Cleveland Clinic journal of medicine

authors：

更新日期：2001-07-01 00:00:00

abstract：:Autosomal dominant polycystic kidney disease (ADPKD) has numerous systemic manifestations and complications. This article gives an overview of hypertension, cardiac complications, and intracranial aneurysms in ADPKD, their pathophysiology, and recent developments in their management. ...

journal_title：Cleveland Clinic journal of medicine

authors： Krishnappa V,Vinod P,Deverakonda D,Raina R

更新日期：2017-06-01 00:00:00

abstract：:Although most patients with emphysema are managed medically, a small subset of severely disabled patients may become candidates for surgery. This paper discusses for the internist who works with emphysema patients the risks, benefits, patient selection criteria, and outcome data for three procedures in current use: bu...

journal_title：Cleveland Clinic journal of medicine

authors： Dasgupta A,Maurer J

更新日期：1999-07-01 00:00:00

abstract：:Giant cell arteritis is a common systemic vasculitis that affects the elderly and has a variable clinical presentation. Physicians should be aware of its different clinical phenotypes so that they can recognize it early and promptly initiate glucocorticoids, the mainstay of therapy. Clinicians should also be familiar ...

journal_title：Cleveland Clinic journal of medicine

authors： Rinden T,Miller E,Nasr R

更新日期：2019-07-01 00:00:00

abstract：:Coronary artery disease is different in women than in men in its pathogenesis, symptoms, and prognosis. Needed is a strategy for detecting and assessing coronary disease specifically in women. This review highlights recent evidence on sex differences in coronary artery disease. ...

journal_title：Cleveland Clinic journal of medicine

authors： Bellasi A,Raggi P,Merz CN,Shaw LJ

更新日期：2007-08-01 00:00:00

abstract：:Thrombotic thrombocytopenic purpura (TTP) is a spectrum of syndromes characterized by thrombocytopenia and microangiopathic hemolytic anemia, manifested by an elevated blood lactate dehydrogenase (LDH) concentration and red blood cell fragments. It classically occurs in patients with a hereditary or acquired lack of A...

journal_title：Cleveland Clinic journal of medicine

authors： Crowther MA,George JN

更新日期：2008-05-01 00:00:00

abstract：:Arthroscopy for degenerative conditions of the knee is among the most commonly employed orthopedic procedures, but its effectiveness (like the effectiveness of many surgical operations) has never been proven in prospective trials. Moreover, the precise mechanism by which arthroscopy improves the course of degenerative...

journal_title：Cleveland Clinic journal of medicine

authors： Bernstein J,Quach T

更新日期：2003-05-01 00:00:00

abstract：:Clinicians are bombarded with information daily by social media, mainstream television news, e-mail, and print and online reports. They usually do not have much control over these information streams and thus are passive recipients, which means they get more noise than signal. Accessing, absorbing, organizing, storing...

journal_title：Cleveland Clinic journal of medicine

authors： Mehta NB,Martin SA,Maypole J,Andrews R

更新日期：2016-08-01 00:00:00

abstract：:Evidence is mounting that depression is a risk factor for the development of cardiovascular disease and portends a worse outcome in cardiac patients. Depression can be easily diagnosed and safely treated in cardiac patients, but it is undertreated. ...

journal_title：Cleveland Clinic journal of medicine

authors： Kemp DE,Malhotra S,Franco KN,Tesar G,Bronson DL

更新日期：2003-09-01 00:00:00

abstract：:An immunocompromised patient presented with chronic low back pain as the initial symptom and a subcutaneous abscess as the initial sign of disseminated aspergillosis. With the rising incidence of immunocompromised patients, cutaneous manifestation of aspergillosis may become more common. ...

journal_title：Cleveland Clinic journal of medicine

authors： Helm TN,Mazanec D

更新日期：1990-01-01 00:00:00

abstract：:Obsessive-compulsive disorder (OCD) is the fourth most common psychiatric disorder. Yet patients often avoid seeking help because they are ashamed. Diagnosis is difficult, but familiarity with the nature of OCD and its current management helps primary care physicians identify patients with OCD and make informed judgme...

journal_title：Cleveland Clinic journal of medicine

authors： El-Sayegh S,Bea S,Agelopoulos A

更新日期：2003-10-01 00:00:00

abstract：:Deep brain stimulation (DBS) is among the most effective approaches for the treatment of patients with advanced movement disorders. In patients with essential tremor, stimulation typically targets the ventral intermediate nucleus of the thalamus. Results of several studies have shown that over a follow-up period of 1 ...

journal_title：Cleveland Clinic journal of medicine

authors： Cooper S,Bowes M

更新日期：2012-07-01 00:00:00

abstract：:Exercise stress electrocardiography is unreliable as a test for obstructive coronary artery disease (CAD) if the patient has left bundle branch block. The authors provide an algorithm for using alternative tests: exercise stress echocardiography, dobutamine echocardiography, computed tomographic (CT) angiography, and ...

journal_title：Cleveland Clinic journal of medicine

authors： Xu B,Cremer P,Jaber W,Moir S,Harb SC,Rodriguez LL

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Coronary artery disease is a major cause of death in transplant recipients. PURPOSE:To review current approaches for the detection, evaluation, and treatment of coronary artery disease in transplant recipients. SUMMARY:Renal transplantation promotes the development of coronary artery disease primarily beca...

journal_title：Cleveland Clinic journal of medicine

authors： Braun WE,Marwick TH

更新日期：1994-09-01 00:00:00

abstract：:COVID-19 infection is associated with several cardiac complications with high rates of adverse outcomes. Cardiac imaging has different utility in different clinical scenarios, and the importance of minimizing healthcare worker exposure should be considered. Cardiac imaging should only be ordered if its benefits outwei...

journal_title：Cleveland Clinic journal of medicine

authors： Wang TKM,Tang WHW,Flamm SD,Griffin B,Dugar S,Grimm RA,Kwon DH

更新日期：2020-05-14 00:00:00

abstract：:Weight-loss drugs are being evaluated for their role in obesity management. This article reviews the available weight-loss drugs, their efficacy and side effects, and their best clinical use. ...

journal_title：Cleveland Clinic journal of medicine

authors： Bersoux S,Byun TH,Chaliki SS,Poole KG

更新日期：2017-12-01 00:00:00

abstract：:Complications of chronic gastroesophageal reflux disease (GERD) run the gamut from erosive esophagitis to esophageal cancer, but all are linked to repeated exposure of the esophagus to caustic gastric and duodenal acid. Progression from one complication to another is not clearly established across the GERD continuum, ...

journal_title：Cleveland Clinic journal of medicine

authors： Fennerty MB

更新日期：2003-11-01 00:00:00

abstract：:Patients with panic disorder often believe they are suffering a myocardial infarction or another life-threatening illness. The history and physical examination and a few tests usually suffice to diagnose this disorder, which is treatable with behavioral therapy, antidepressants, and benzodiazepines. ...

journal_title：Cleveland Clinic journal of medicine

authors： Muzina DJ,Malone DA

更新日期：1997-09-01 00:00:00

abstract：:Although hypertension has been defined numerically as blood pressure levels above 140/90 mmHg, there is no doubt that a blood pressure level within the "normal" range increases the stress on a diseased heart. For this reason, vasodilator therapy is often successful in treating congestive heart failure. The authors pro...

journal_title：Cleveland Clinic journal of medicine

authors： Fouad-Tarazi FM,Hobbs RE

更新日期：1989-06-01 00:00:00

abstract：:You can find evidence-based answers to clinical questions quickly by searching online medical databases. The key is to be selective, on the basis of the type of information you need. Online textbooks, consensus guidelines systematic reviews, and MEDLINE are all available. ...

journal_title：Cleveland Clinic journal of medicine

authors： Mehta N,Jain A

更新日期：2001-04-01 00:00:00

abstract：:Patients with pulmonary arterial hypertension (PAH) may present to internists, rheumatologists, cardiologists, or pulmonologists. This breadth of clinicians who encounter PAH patients, together with the complicated nature of PAH as a disease entity, argues for a shared-care approach to the management of these patients...

journal_title：Cleveland Clinic journal of medicine

authors： Mughal MM,Mandell B,James K,Stelmach K,Minai OA

更新日期：2003-04-01 00:00:00