Panic disorder in primary care: a cause of unexplained symptoms.

abstract：:Focal acantholytic dyskeratosis consistent with the clinical and histological features of Darier's type of transient acantholytic dermatosis occurred in a man with myelodysplasia. Topical steroids and systemic antihistamines provided temporary and moderate relief from pruritus, but failed to control the dermatosis. ...

journal_title：Cleveland Clinic journal of medicine

authors： Rockley PF,Bergfeld WF,Tomecki KJ,Brydon JK

更新日期：1990-09-01 00:00:00

abstract：:Glomerulonephritis (GN) is a common manifestation of the antineutrophil cytoplasmic antibody-associated systemic vasculitides (AASV), which include granulomatosis with polyangiitis and microscopic polyangiitis. The level of renal involvement at presentation is highly predictive of survival and should be assessed early...

journal_title：Cleveland Clinic journal of medicine

authors： de Groot K

更新日期：2012-11-01 00:00:00

abstract：:Concern has been raised about whether the fluid retention caused by thiazolidinediones (TZDs, ie, rosiglitazone and pioglitazone) can cause or exacerbate congestive heart failure. Although fluid retention is a worrisome side effect of TZDs, current evidence does not link fluid retention caused by TZDs with worsening h...

journal_title：Cleveland Clinic journal of medicine

authors： Tang WH

更新日期：2006-04-01 00:00:00

abstract：:Obstructive sleep apnea (OSA) is a serious condition associated with impaired quality of life, depression, drowsy driving and motor vehicle accidents, metabolic disease, and cognitive decline. The mechanisms accounting for OSA and metabolic disease include hypoxia, sleep fragmentation, and systemic inflammation. OSA a...

journal_title：Cleveland Clinic journal of medicine

authors： Walia HK

更新日期：2019-09-01 00:00:00

abstract：:Congestive heart failure is the most common cause of death in patients with thalassemia, as chronic accumulation of iron due to regular blood transfusions leads to biventricular systolic dysfunction and death at a very young age. The quantity of iron deposited in the heart is a key determinant of outcome. Early diagno...

journal_title：Cleveland Clinic journal of medicine

authors： Jabbar DA,Davison G,Muslin AJ

更新日期：2007-11-01 00:00:00

abstract：:Numerous immunomodulating agents are currently being studied in clinical trials for the treatment of COVID-19, including interferon therapies. Interferons are naturally occurring host antiviral proteins upstream of the inflammatory pathway that are released by host cells in response to the presence of viral pathogens....

journal_title：Cleveland Clinic journal of medicine

authors： Calabrese LH,Lenfant T,Calabrese C

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:Nicotinic acid, widely used to lower serum cholesterol levels, may rarely cause cholestatic jaundice. SUMMARY:A 61-year-old white man with hypercholesterolemia complained of marked pruritus and became jaundiced after taking 3.0 g of crystalline nicotinic acid daily for 13 months. His total serum bilirubin l...

journal_title：Cleveland Clinic journal of medicine

authors： Patel SD,Taylor HC

更新日期：1994-01-01 00:00:00

abstract：:Development of medical devices requires interaction between physicians and industry that is considerably more intimate than that in pharmaceutical development. Progress in procedure-based medicine would be stalled if this collaboration were eliminated. This degree of interaction, however, creates conflicts of interest...

journal_title：Cleveland Clinic journal of medicine

authors： LaViolette PA

更新日期：2007-03-01 00:00:00

abstract：:Most patients find some relief with current agents, even though a poor understanding of the causes of chronic primary headache limits prophylaxis and treatment. The author reviews current preventive and treatment strategies for migraine, chronic tension headache, cluster headache, and substance withdrawal headache. ...

journal_title：Cleveland Clinic journal of medicine

authors： Solomon GD

更新日期：2001-11-01 00:00:00

abstract：:The ongoing outbreak of Zika virus infection that began in South America and Central America in 2014 is worrisome because of associations with fetal microcephaly and with Guillain-Barré syndrome. Here we summarize what has happened and what is known so far. As the outbreak continues to evolve, we urge clinicians to wa...

journal_title：Cleveland Clinic journal of medicine

authors： Flores MS,Burgess TH,Rajnik M

更新日期：2016-04-01 00:00:00

abstract：:An over-the-counter at-home test for human immunodeficiency virus (HIV) infection has been approved and will likely be available soon. It is intended to decrease the percentage of HIV-infected people unaware of their infection (estimated at 18% of the 1.2 million people infected in the United States). Since early and ...

journal_title：Cleveland Clinic journal of medicine

authors： Koval CE

更新日期：2012-10-01 00:00:00

abstract：:Therapy with nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) has long been the cornerstone of pharmacologic management of patients with osteoarthritis (OA) and rheumatoid arthritis (RA). Many patients with OA or RA, however, are at increased risk of developing clinically significant adverse events associate...

journal_title：Cleveland Clinic journal of medicine

authors： Schnitzer TJ,Hochberg MC

更新日期：2002-01-01 00:00:00

abstract：:Weight-loss drugs are being evaluated for their role in obesity management. This article reviews the available weight-loss drugs, their efficacy and side effects, and their best clinical use. ...

journal_title：Cleveland Clinic journal of medicine

authors： Bersoux S,Byun TH,Chaliki SS,Poole KG

更新日期：2017-12-01 00:00:00

abstract：:Blood tests are available that measure levels of immunoglobulin E (IgE) against specific allergens such as foods, inhalants, medications, latex, and venoms. These tests can confirm the diagnosis of an allergic disorder, supplementing a clinical history consistent with an immediate allergic reaction. They are particula...

journal_title：Cleveland Clinic journal of medicine

authors： Siles RI,Hsieh FH

更新日期：2011-09-01 00:00:00

abstract：:Clinical imaging and serologic testing are increasingly replacing biopsy for diagnosing hepatic diseases. However, more biopsies are being done to stage and grade hepatitis C and fatty liver disease, to diagnose space-occupying lesions (typically with fine-needle aspiration biopsy), and to assess response to therapy. ...

journal_title：Cleveland Clinic journal of medicine

authors： Siegel CA,Silas AM,Suriawinata AA,van Leeuwen DJ

更新日期：2005-03-01 00:00:00

abstract：:Patients with muscle diseases are often seen initially by general practitioners. This article reviews how to evaluate and manage such patients, including those taking a statin, how to interpret creatine kinase (CK) test results, and how to recognize common as well as potentially dangerous myopathies. ...

journal_title：Cleveland Clinic journal of medicine

authors： Oddis CV

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Certain fluorocarbon polymers can produce a clinical syndrome called polymer fume fever when the products of pyrolysis are inhaled. SUMMARY:A previously healthy 21-year-old white man presented with severe chest tightness, difficulty in breathing, pyrexia, nausea, vomiting, and a dry irritating cough. These ...

journal_title：Cleveland Clinic journal of medicine

authors： Silver MJ,Young DK

更新日期：1993-11-01 00:00:00

abstract：:Annular pancreas is a congenital anomaly which, though present at birth, may cause few symptoms until adulthood. A case of annular pancreas with intermittent duodenal obstruction is described in a 49-year-old alcoholic man. Few other entities cause such obstruction. In similar cases, clinical suspicion of annular panc...

journal_title：Cleveland Clinic journal of medicine

authors： Sperrazza JC,Flanagan RA Jr,Katlic MR

更新日期：1992-03-01 00:00:00

abstract：:The decline in testosterone with age has been associated with specific physical changes that affect quality of life and life expectancy, although a cause-and-effect relationship is yet to be established. While female menopause is rapid and well described, "male menopause" or androgen decline in older men is gradual an...

journal_title：Cleveland Clinic journal of medicine

authors： McGill JJ,Shoskes DA,Sabanegh ES

更新日期：2012-11-01 00:00:00

abstract：:Arthroscopy for degenerative conditions of the knee is among the most commonly employed orthopedic procedures, but its effectiveness (like the effectiveness of many surgical operations) has never been proven in prospective trials. Moreover, the precise mechanism by which arthroscopy improves the course of degenerative...

journal_title：Cleveland Clinic journal of medicine

authors： Bernstein J,Quach T

更新日期：2003-05-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is an important cause of death in patients with liver disease, and its incidence appears to be rising in the United States. Because early diagnosis improves the chances of survival, it is important to identify patients who would benefit from surveillance. Once HCC is suspected on surveil...

journal_title：Cleveland Clinic journal of medicine

authors： Murali AR,Romero-Marrero C,Aucejo F,Menon KV

更新日期：2013-10-01 00:00:00

abstract：:The American Heart Association issued a science advisory on depression and coronary heart disease (CHD) in 2008. This paper reviews the purpose and content of the advisory and discusses reactions and new information that have followed the advisory's release. Both the advisory and subsequent data support routine screen...

journal_title：Cleveland Clinic journal of medicine

authors： Bigger JT,Glassman AH

更新日期：2010-07-01 00:00:00

abstract：:The neurohormone arginine vasopressin (AVP) is a promising target in the treatment of heart failure because AVP promotes congestion and hyponatremia, each of which is associated with poor outcomes. Diuretics are standard therapy for heart failure, but they have several limitations, including worsening renal function a...

journal_title：Cleveland Clinic journal of medicine

authors： Gheorghiade M

更新日期：2006-06-01 00:00:00

abstract：:Cancer patients and their families often ask their primary care physicians if a new treatment reported in the news can help them. Physicians familiar with the long and complicated process of oncologic clinical trials are in the best position to assess the potential for clinical benefit from a new antineoplastic therap...

journal_title：Cleveland Clinic journal of medicine

authors： Markman M

更新日期：2002-05-01 00:00:00

abstract：:Clinicians are bombarded with information daily by social media, mainstream television news, e-mail, and print and online reports. They usually do not have much control over these information streams and thus are passive recipients, which means they get more noise than signal. Accessing, absorbing, organizing, storing...

journal_title：Cleveland Clinic journal of medicine

authors： Mehta NB,Martin SA,Maypole J,Andrews R

更新日期：2016-08-01 00:00:00

abstract：:Percutaneous transluminal coronary angioplasty (PTCA) of stenotic saphenous vein grafts is less invasive than repeat coronary bypass grafting; however, this procedure is complicated by atheromatous embolization in 2.5%-3.0% of cases, an incidence significantly higher than in angioplasty of native coronary vessels. We ...

journal_title：Cleveland Clinic journal of medicine

authors： Trono R,Sutton C,Hollman J,Suit P,Ratliff NB

更新日期：1989-09-01 00:00:00

abstract：:The threshold for testing for hepatitis C virus (HCV) should be low for persons with any risk factor for HCV infection. Current practice calls for first screening for antibodies to HCV and then testing for HCV RNA in those in whom antibodies are detected. Viral testing can distinguish between active and resolved HCV i...

journal_title：Cleveland Clinic journal of medicine

authors： Carey W

更新日期：2003-09-01 00:00:00

abstract：:Studies published during the past year on the treatment of several infectious diseases provide valuable information that should enable us to treat our patients more effectively. Among those findings: Oral vancomycin (Vancocin) is superior to oral metronidazole (Flagyl) for treating patients with severe Clostridium dif...

journal_title：Cleveland Clinic journal of medicine

authors： Longworth DL

更新日期：2008-08-01 00:00:00

abstract：:During a 10-year period, 60 patients with confirmed diagnoses of pheochromocytoma underwent a total of 63 surgical procedure. To control extreme blood pressure elevations, 6 patients received phenoxybenzamine preoperatively and 28 patients received prazosin. The remaining 29 patients received neither drug. Intravenous...

journal_title：Cleveland Clinic journal of medicine

authors： Boutros AR,Bravo EL,Zanettin G,Straffon RA

更新日期：1990-10-01 00:00:00

abstract：:Exercise helps prevent and improve atherosclerosis and other chronic diseases, and physicians should encourage their patients to exercise more. Unfortunately, there are many barriers to prescribing exercise. To help patients start exercising and stay with it, clinicians need to address specifics. Several guidelines ar...

journal_title：Cleveland Clinic journal of medicine

authors： Fletcher G,Trejo JF

更新日期：2005-08-01 00:00:00