Exercise performance after repair of anomalous origin of the left coronary artery from the pulmonary artery.

abstract：BACKGROUND:In contrast to systolic function, which is relatively well preserved with advancing age, diastolic function declines steadily after age 30. Our goal was to determine whether changes in diastolic function that occur with aging could be reversed with exercise training. Methods and Results-- Adult (6-month-old)...

journal_title：Circulation

authors： Brenner DA,Apstein CS,Saupe KW

更新日期：2001-07-10 00:00:00

abstract：BACKGROUND:Vascular events during initial reperfusion after a period of hypothermic cardioplegic ischemia may play an important role in the recovery of mechanical function. Prior studies have shown (1) that dysfunction of the postischemic myocardium after normothermic ischemia can be ameliorated by vasodilation and (2)...

journal_title：Circulation

authors： Kawata H,Aoki M,Mayer JE Jr

更新日期：1993-11-01 00:00:00

abstract：:Of 1,801 patients in the 1985-1986 Percutaneous Transluminal Coronary Angioplasty (PTCA) Registry, 122 (6.8%) had periprocedural occlusion (4.9% in the catheterization laboratory, 1.9% outside the laboratory). Baseline patient factors independently associated with increased occlusion rates included triple-vessel disea...

journal_title：Circulation

authors： Detre KM,Holmes DR Jr,Holubkov R,Cowley MJ,Bourassa MG,Faxon DP,Dorros GR,Bentivoglio LG,Kent KM,Myler RK

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:NADH/NADPH oxidase is an important source of superoxide in the vasculature. Recently, we found that polymorphism of the gene p22phox, a critical component of this oxidase, is associated with a risk of coronary artery disease. The aim of this study was to investigate the localization of p22phox in human coron...

journal_title：Circulation

authors： Azumi H,Inoue N,Takeshita S,Rikitake Y,Kawashima S,Hayashi Y,Itoh H,Yokoyama M

更新日期：1999-10-05 00:00:00

abstract：BACKGROUND:Classically, intrinsic coagulation proteins are thought to have a minor role in hemostasis. Recently, these proteins, especially FXII, were implicated as possible key players in the pathogenesis of arterial thrombosis. This study aims to determine the risks of arterial thrombosis conferred by increased activ...

journal_title：Circulation

authors： Siegerink B,Govers-Riemslag JW,Rosendaal FR,Ten Cate H,Algra A

更新日期：2010-11-02 00:00:00

abstract：:BACKGROUND. The fenestrated Fontan operation has been applied to high-risk patients with univentricular hearts, resulting in improved survival. The purpose of this study was to determine the hemodynamic factors responsible for these improved results. METHODS AND RESULTS. We performed the fenestrated Fontan operation i...

journal_title：Circulation

authors： Mavroudis C,Zales VR,Backer CL,Muster AJ,Latson LA

更新日期：1992-11-01 00:00:00

abstract：:Amiodarone is the most effective antiarrhythmic drug for maintaining sinus rhythm for patients with atrial fibrillation. Extra-cardiac side effects have been a limiting factor, especially during chronic use, and may offset its benefits. Dronedarone is a noniodinated benzofuran derivative of amiodarone that has been de...

journal_title：Circulation

authors： Patel C,Yan GX,Kowey PR

更新日期：2009-08-18 00:00:00

abstract：:Experimental studies have suggested that electrocardiographic recognition of left ventricular hypertrophy depends on geometric relationships involving wall thickness and chamber size. To determine the clinical significance of these observations, we studied the effects of echocardiographic LV mass (LVM), posterior wall...

journal_title：Circulation

authors： Devereux RB,Phillips MC,Casale PN,Eisenberg RR,Kligfield P

更新日期：1983-04-01 00:00:00

abstract：:While continuing a study of immunologic and virologic aspects of the postpericardiotomy syndrome (PPS) in infants and children, we undertook a companion study in adults. Whereas the incidence in 119 children was 27.8%, as is usual for our hospital, the incidence in 142 adults was 17.6%. Most of the operations (95 of 1...

journal_title：Circulation

authors： Engle MA,Gay WA Jr,McCabe J,Longo E,Johnson D,Senterfit LB,Zabriskie JB

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Higher levels of physical activity are associated with fewer cardiovascular disease (CVD) events. Although the precise mechanisms underlying this inverse association are unclear, differences in several cardiovascular risk factors may mediate this effect. METHODS AND RESULTS:In a prospective study of 27,055 ...

journal_title：Circulation

authors： Mora S,Cook N,Buring JE,Ridker PM,Lee IM

更新日期：2007-11-06 00:00:00

abstract：BACKGROUND:Catheter ablation of the posteroseptal right atrium has been proposed for control of ventricular rate in patients with tachycardic atrial fibrillation (AF). However, the exact mechanism of rate control is unclear. Because the ablation site corresponds to the location of the slow pathway in patients with AV n...

journal_title：Circulation

authors： Kreiner G,Heinz G,Siostrzonek P,Gössinger HD

更新日期：1996-01-15 00:00:00

abstract：BACKGROUND:This study compared the efficacy of ischemic preconditioning (IPC) and sodium-hydrogen exchanger (NHE)-1 inhibition to reduce infarct size (IS) induced by a 90-minute ischemic insult and examined the interaction between NHE-1 inhibition and IPC. METHODS AND RESULTS:In a canine infarct model, either IPC, pro...

journal_title：Circulation

authors： Gumina RJ,Buerger E,Eickmeier C,Moore J,Daemmgen J,Gross GJ

更新日期：1999-12-21 00:00:00

abstract：BACKGROUND:It is not known whether subspecialty care by cardiologists improves outcomes in heart failure patients from the community over care by other physicians. METHODS AND RESULTS:Using administrative data, we monitored 38 702 consecutive patients with first-time hospitalization for heart failure in Ontario, Canad...

journal_title：Circulation

authors： Jong P,Gong Y,Liu PP,Austin PC,Lee DS,Tu JV

更新日期：2003-07-15 00:00:00

abstract：BACKGROUND:Erythropoietin (Epo) receptors (EpoRs) are expressed in the heart. We have recently demonstrated that the endogenous Epo-EpoR system plays an important protective role in myocardial ischemia in mice and humans. In the present study, we tested our hypothesis that the endogenous Epo-EpoR system in nonhematopoi...

journal_title：Circulation

authors： Asaumi Y,Kagaya Y,Takeda M,Yamaguchi N,Tada H,Ito K,Ohta J,Shiroto T,Shirato K,Minegishi N,Shimokawa H

更新日期：2007-04-17 00:00:00

abstract：:One thousand four Medtronic Hall valves (601 mitral, 398 aortic, and five tricuspid) were implanted in 847 patients between December 1979 and June 1987. Total experience at the end of June 1987 was 2,640 patient-years of follow-up. Prothrombin time ratios were reviewed for all patients (16,866 observations), and these...

journal_title：Circulation

authors： Butchart EG,Lewis PA,Grunkemeier GL,Kulatilake N,Breckenridge IM

更新日期：1988-09-01 00:00:00

abstract：:This is a report of a 10-year-old child who underwent surgery for complex congenital heart disease consisting of corrected transposition of the great vessels, ventricular septal defect, patent ductus arterisus, severe left-sided atrioventricular (AV) valve insuffieicney (Ebstein's deformity) and Wolff-Parkinson-White ...

journal_title：Circulation

authors： Benson DW Jr,Gallagher JJ,Oldham HN,Sealy WC,Sterba R,Spach MS

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:The long-term administration of ACE inhibitors to selected patients with left ventricular dysfunction appears to reduce the incidence of recurrent myocardial infarction (MI) and unstable angina pectoris. The mechanisms responsible for the reduction in ischemic events are unknown, but likely candidates includ...

journal_title：Circulation

authors： Vaughan DE,Rouleau JL,Ridker PM,Arnold JM,Menapace FJ,Pfeffer MA

更新日期：1997-07-15 00:00:00

abstract：BACKGROUND:Significant gender-related differences exist in the development of left ventricular hypertrophy (LVH). In addition, administration of 17beta-estradiol (E2) to ovariectomized female mice attenuates the development of LVH, demonstrating an antagonistic role for E2 in this process, although no molecular mechani...

journal_title：Circulation

authors： Babiker FA,De Windt LJ,van Eickels M,Thijssen V,Bronsaer RJ,Grohé C,van Bilsen M,Doevendans PA

更新日期：2004-01-20 00:00:00

abstract：BACKGROUND:The rate-corrected QT interval (QTc) is heritable, and the discovery of quantitative trait loci that influence the QTc would be an important step in identifying the genes responsible for life-threatening arrhythmias in the general population. We studied 66 pairs of unselected normal dizygotic (DZ) twin subje...

journal_title：Circulation

authors： Busjahn A,Knoblauch H,Faulhaber HD,Boeckel T,Rosenthal M,Uhlmann R,Hoehe M,Schuster H,Luft FC

更新日期：1999-06-22 00:00:00

abstract：BACKGROUND:Altered composition of the gut microbiota is involved in both the onset and progression of obesity and diabetes mellitus. However, the link between gut microbiota and obesity-related cardiovascular complications has not been explored. The present study was designed to investigate the role of Akkermansia muci...

journal_title：Circulation

authors： Li J,Lin S,Vanhoutte PM,Woo CW,Xu A

更新日期：2016-06-14 00:00:00

abstract：BACKGROUND:Varicose veins are a common problem with no approved medical therapies. Although it is believed that varicose vein pathogenesis is multifactorial, there is limited understanding of the genetic and environmental factors that contribute to their formation. Large-scale studies of risk factors for varicose veins...

journal_title：Circulation

authors： Fukaya E,Flores AM,Lindholm D,Gustafsson S,Zanetti D,Ingelsson E,Leeper NJ

更新日期：2018-12-18 00:00:00

abstract：BACKGROUND:Adenosine has several potentially cardioprotective effects. We hypothesized that the effects of endogenous adenosine vary with degree of ischemia and that elevating endogenous levels is protective. METHODS AND RESULTS:Isolated blood-perfused piglet hearts underwent 120 minutes of low-flow ischemia (10% flow...

journal_title：Circulation

authors： Sommerschild HT,Grund F,Offstad J,Jynge P,Ilebekk A,Kirkebøen KA

更新日期：1997-11-04 00:00:00

abstract：BACKGROUND:In vitro experiments have shown that holmium laser energy can effectively ablate even calcified plaque in human arterial vessels. Because high-energy densities from holmium lasers can easily be transmitted through quartz fibers, this solid-state laser has been suggested as an alternative intraluminal treatme...

journal_title：Circulation

authors： Hassenstein S,Hanke H,Kamenz J,Oberhoff M,Hanke S,Riessen R,Haase KK,Betz E,Karsch KR

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:We measured cardiovagal baroreflex gain and its vascular mechanical and neural components during dynamic baroreflex engagement in 10 young untrained men, 6 older untrained men, and 12 older, physically active men. METHODS AND RESULTS:Our newly developed assessment of beat-to-beat carotid diameters during ba...

journal_title：Circulation

authors： Hunt BE,Farquhar WB,Taylor JA

更新日期：2001-05-22 00:00:00

abstract：:To determine the effects of coronary angioplasty on coronary flow reserve (CFR), we studied 32 patients before and immediately after single-vessel coronary angioplasty and 31 patients evaluated late after angioplasty (7.5 +/- 1.2 months, mean +/- SEM). The geometry (percent area stenosis and minimal cross-sectional ar...

journal_title：Circulation

authors： Wilson RF,Johnson MR,Marcus ML,Aylward PE,Skorton DJ,Collins S,White CW

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:Cardiac dyssynchrony in the failing heart worsens global function and efficiency and generates regional loading disparities that may exacerbate stress-response molecular signaling and worsen cell survival. We hypothesized that cardiac resynchronization (CRT) from biventricular stimulation reverses such molec...

journal_title：Circulation

authors： Chakir K,Daya SK,Tunin RS,Helm RH,Byrne MJ,Dimaano VL,Lardo AC,Abraham TP,Tomaselli GF,Kass DA

更新日期：2008-03-18 00:00:00

abstract：BACKGROUND:Q waves on a 12-lead ECG are markers of a prior myocardial infarction (MI). However, they may regress or even disappear over time, and there is no specific ECG sign of a non-Q-wave MI. Fragmented QRS complexes (fQRSs), which include various RSR' patterns, without a typical bundle-branch block are markers of ...

journal_title：Circulation

authors： Das MK,Khan B,Jacob S,Kumar A,Mahenthiran J

更新日期：2006-05-30 00:00:00

abstract：BACKGROUND:Peak dP/dt is a good index of ventricular performance that is not influenced by afterload, wall motion abnormalities, or the variations in ventricular anatomy and morphology commonly encountered among patients with congenital heart disease. Unfortunately, the clinical utility of peak dP/dt has been limited b...

journal_title：Circulation

authors： Rhodes J,Udelson JE,Marx GR,Schmid CH,Konstam MA,Hijazi ZM,Bova SA,Fulton DR

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:A major advantage of coronary artery bypass graft surgery (CABG) relative to percutaneous coronary intervention is its durability, yet there is a paucity of information on rates and predictors of repeat coronary revascularization after CABG in the modern era. METHODS AND RESULTS:We included patients ≥65 yea...

journal_title：Circulation

authors： Fosbøl EL,Zhao Y,Shahian DM,Grover FL,Edwards FH,Peterson ED

更新日期：2013-04-23 00:00:00

abstract：:Contrary to opinions generally accepted in the past, CHD is very common in both African-American men and women, with incidence rates approaching those of US Caucasians. Higher prevalence of hypertension, diabetes, cigarette smoking, and obesity all contribute to the high level of CHD in African-Americans. Additional r...

journal_title：Circulation

authors： Curry CL

更新日期：1991-04-01 00:00:00