Abstract:
OBJECTIVE:Composite restorative materials represent one of the most important groups of materials in contemporary dental practice. However, their incomplete polymerization may lead to monomer-induced genotoxicity. The objective of this study was to evaluate the genotoxicity of three flowable (Filtek Supreme XT Flow, Tetric EvoFlow, Gradia Direct Flo) and three non-flowable dental composite materials (Filtek Z250, Tetric EvoCeram, Gradia Direct Posterior). MATERIALS AND METHODS:Genotoxicity assessment of composite materials was carried out in vitro in human peripheral blood leukocytes using the alkaline single-cell gel electrophoresis technique (comet assay). Prepared materials were eluted in saline solution for 1 h, 1 day and 5 days. Thereafter leukocyte cultures were treated with different concentrations of eluates obtained from each of the tested dental composite materials. Kruskall-Wallis non-parametric test was used for statistical analysis (p < 0.05). RESULTS:The tested materials did not show genotoxic effects after exposure of leucocytes to 1 h eluates. Culture treated with 1 day eluates of all tested materials, only at a highest concentration (10(-2)), affected the measured cytogenetic parameters. Of all tested materials, only Filtek Z250 and Filtek Supreme XT Flow did not exhibit a genotoxic effect in cultures that were under the influence of 5 day eluates. CONCLUSION:Tested materials exhibited limited genotoxic activity in peripheral blood leukocytes. Since the effect was observed only in leukocyte cultures treated by 1-day eluates at the highest concentration (10(-2)) and it decreases in cultures exposed to 5 day eluates, it should not pose a significant risk to the human genome.
journal_name
Acta Odontol Scandjournal_title
Acta odontologica Scandinavicaauthors
Tadin A,Marovic D,Galic N,Milevoj A,Medvedec Mikic I,Zeljezic Ddoi
10.3109/00016357.2012.734419subject
Has Abstractpub_date
2013-05-01 00:00:00pages
923-9issue
3-4eissn
0001-6357issn
1502-3850journal_volume
71pub_type
杂志文章abstract::Using dentist characteristics, our aim was to evaluate the reasons for replacements of fillings, the age of failed restorations in the posterior teeth of young adults, and replacement rates. Altogether 205 patient records from the Public Oral Health Service of the City of Vantaa, Finland were evaluated. Patient age wa...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163502762667333
更新日期:2002-12-01 00:00:00
abstract::The aim of this study was to obtain information on restorative dental care in Finland and to analyze the changes in treatment over a 5-year period. A random sample of dentists was drawn from the registers of the health authorities and the dental association in Finland, and in the spring of 1997 a questionnaire was sen...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163501750157090
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVE:The global pandemic of coronavirus disease-19, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is the latest hazard facing healthcare workers (HCW) including dental care workers (DCW). It is clear that the major mode of SARS-CoV-2 transmission is the airborne route, through inhalat...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2020.1810769
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVES:The purpose of this investigation was to analyze epidemiological patterns, clinical features and the management of odontogenic infections in patients undergoing treatment in a dental emergency outpatient care unit. STUDY DESIGN:A retrospective analysis of 58 161 case records of patients presenting to an eme...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2012.696694
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:Local anesthetics are the most commonly used drugs in dentistry, with a wide range of effects, including antimicrobial activity. High antimicrobial effects have recently been reported on oral microbes from articaine hydrochloride, revealed by the minimum inhibitory concentration and minimal bactericidal conce...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350802443466
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:Polypharmacy is a common cause of xerostomia. This study aimed to investigate whether xerostomia could be an adverse drug event of mouthwashes, when they are used for longer than 2 weeks by patients taking polypharmacy. MATERIALS AND METHODS:This cross-sectional observational study included 120 hospitalized ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.923108
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:Antiseptics and antibiotics delivered either locally or systemically have been used as an adjunct to scaling and root planing procedures in order to control the subgingival biofilm and thereby enhancing the treatment outcome. The results presented in the literature are, however, inconclusive. Povidone-iodine ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.1080/00016350600613625
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:The aim was to investigate the relationship between soft drink consumption, oral health and some lifestyle factors in Swedish adolescents. MATERIALS AND METHODS:A clinical dental examination and a questionnaire concerning lifestyle factors, including drinking habits, oral hygiene, dietary consumption, physic...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.946964
更新日期:2014-11-01 00:00:00
abstract::A follow-up study was performed in 128 patients who had started dental treatment at the Faculty of Odontology in Göteborg one year previously. 58 patients had been referred to the Department of Stomatognathic Physiology for investigation and treatment of mandibular dysfunction (TMJ patients) and 70 patients had come t...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358009033598
更新日期:1980-01-01 00:00:00
abstract::Unfixed as well as glutaraldehyde-fixed pelleted cells from pure cultures of Streptococcus mutans subspecies sobrinus (B13) were embedded in glycolmethacrylate. Ultrathin were sections immunoperoxidase labelled with rabbit anti-S. mutans sobrinus gamma-globulin. It was found that unfixed specimens became labelled as p...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358209024071
更新日期:1982-01-01 00:00:00
abstract::The craniofacial morphology of 48 consecutive adult males with isolated cleft palate was studied by means of lateral cephalograms at the mean age of 18.8 years. Twelve of the patients had received pharyngeal flap surgery between 4 and 12 years of age (mean age 6 years) to improve speech. No significant differences wer...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350310003846
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare the protective effect of TiF(4), SnF(2), and NaF treatment on the development of erosion-like lesions in pellicle-covered human enamel. MATERIAL AND METHODS:Twelve human molars were each divided into 5 specimens, 4 of which were immersed in saliva for 2 h. Three pellicle-...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350701477581
更新日期:2007-10-01 00:00:00
abstract::In this methodological study we investigated the usefulness and reliability of a questionnaire designed to capture 4 aspects of parental dental attitudes: dental knowledge, child oral health behavior, perceived importance of dental related aims, and parental responsibility. The study was undertaken in a group of 140 p...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163501300035706
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare the fracture resistance of endodontically treated maxillary central incisors with incomplete crown ferrules after chewing simulation. MATERIAL AND METHODS:Forty caries-free maxillary central incisors were divided into 4 groups (n = 10). Endodontic treatment was performed....
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350500331120
更新日期:2006-02-01 00:00:00
abstract::The frequency of temporomandibular disorders (TMDs) and radiologically observed abnormalities in the condyles of the temporomandibular joints (TMJs) of professional violin and viola players was investigated in 26 orchestra violinists/violists (VP group) and in their sex-, age-, and dentition-matched controls (C group)...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359509005951
更新日期:1995-04-01 00:00:00
abstract::The purpose of this study was to record the caries status in children attending public primary schools in Nairobi. The sample comprised 513 children, 262 aged 6-8 years and 251 aged 13-15 years. The children were drawn from six randomly selected schools in the city. Clinical examination was carried out in a room with ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359209012772
更新日期:1992-10-01 00:00:00
abstract:BACKGROUND:The coronavirus disease-19 (COVID-19) pandemic caused by the severe acute respiratory syndrome Coronavirus -2 is unceasing, and the consensus is that the dental profession has to co-exist with this vicious foe for the foreseeable future. Dental professionals in resource poor countries, as opposed to those in...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2020.1804073
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVES:The primary objective of this study was to investigate the association of systemic diseases, use of medications, allergies and tobacco habits with geographic tongue (GT) and fissured tongue (FT) lesions. The secondary objectives were to evaluate the clinical characteristics of tongue lesions and to compare t...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2015.1087046
更新日期:2016-01-01 00:00:00
abstract::The enzyme beta-glucuronidase (E.C. 3.2.1.31.) has been studied in developing teeth and bone of Sprague-Dawley rats and Macaque monkeys (Macaca Irus) by means of histochemistry using naphthol-AS-BI-beta-D-glucuronide as substrate and hexazotized pararosanilin as coupling reagent. Since beta-glucuronidase is sensitive ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357509026357
更新日期:1975-01-01 00:00:00
abstract::175 'epulides' were studied clinically and histologically. The lesions were histologically reclassified into three groups: granulomatous, fibromatous and giant cell lesions. The granulomatous group was four times and the giant cell group 1.5 times more frequent in females. It is suggested that the expression epulis sh...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358309162306
更新日期:1983-01-01 00:00:00
abstract::The purpose of this study was to determine the sensitivity, specificity, positive and negative predictive values for Corah's Dental Anxiety Scale (DAS) and two modified versions of it (MDAS; MDAS/4). A questionnaire was mailed to a simple random sample of 1,190 25-year-old residents in the west of Norway in 1997. Half...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350050217091
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVE:This study evaluated the influence of surface characteristics of various denture lining materials on the adherence of Candida albicans. MATERIALS AND METHODS:Four different types of materials (tissue conditioners, acrylic and silicone soft liners and hard reline materials) were selected. Disk-shaped material...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2012.671360
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to analyze the clinicopathological and immunohistochemical features of oral papillomas. MATERIALS AND METHODS:Biopsies of oral papillomas analyzed in the laboratory between 1996-2012 were extracted from the database and used to conduct this retrospective review. The following clinic...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.996186
更新日期:2015-01-01 00:00:00
abstract::In a 5-year clinical trial it was observed that the marginal degradation of class-II amalgam restorations could be related to the bulk of the restoration. The association between the occlusal cavity depth and the marginal degradation was observed after 6 months and varied for the different types of alloy. Ridit scores...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359109005888
更新日期:1991-04-01 00:00:00
abstract:OBJECTIVE:To estimate the prevalence of dental erosive wear among five-year-olds in Bergen, Norway, and to investigate associations between background factors and the condition. METHODS:A total of 387 children received a dental examination in five Public Dental Service clinics in Bergen, Norway. The parents responded ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2020.1791357
更新日期:2020-07-21 00:00:00
abstract::A 55Fe excited X-ray fluorescence method has been developed for the quantitative nondestructive analysis of Ca content in surface layers of teeth. To eliminate the effects due to curved enamel surface and the localisation of the tooth a special measuring geometry was constructed. The reproducibility of the method rema...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358209041119
更新日期:1982-01-01 00:00:00
abstract::The aim of this study was to analyze the timing of first fillings posteruptively in a cohort comprising 51 asthmatic children receiving inhaled corticosteroids and living in three communities in Ostrobothnia, Finland. They had all been born in the 1980s and had had asthma check-ups in the local asthma policlinic. A gr...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163598423018
更新日期:1998-02-01 00:00:00
abstract::Recent studies on prenatal innervation of the jaws have shown that three separate main innervation paths, constituting three bilateral neural developmental fields (incisor field, canine/premolar field, molar field) exist in each jaw. In this communication the sequences in which the fields are innervated are indicated....
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:The aim of present study was to determine the effects of conjugated linoleic acid enriched milk on alveolar bone loss, hyperglycaemia, oxidative stress and apoptosis in ligature-induced periodontal disease in diabetic rat model. METHODS:Wistar rats were divided into six experimental groups: 1; non-ligated (N...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2016.1244355
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:Semaphorin 3A (Sema3A) is an essential chemorepellant controlling peripheral axon pathfinding and patterning, but also serves non-neuronal cellular functions. Incisors of rodent are distinctive from molars as they erupt continuously, have only one root and enamel is present only on the labial side. The aim of...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2011.600717
更新日期:2012-05-01 00:00:00