Abstract:
OBJECTIVE:Semaphorin 3A (Sema3A) is an essential chemorepellant controlling peripheral axon pathfinding and patterning, but also serves non-neuronal cellular functions. Incisors of rodent are distinctive from molars as they erupt continuously, have only one root and enamel is present only on the labial side. The aim of this study is to address putative regulatory roles of Sema3A chemorepellant in the development of incisor innervation and formation. MATERIALS AND METHODS:This study analyzed expression of Sema3A mRNAs during embryonic and early post-natal stages of mouse mandibular incisor using sectional radioactive in situ hybridization. RESULTS:Although Sema3A mRNAs were observed in condensed dental mesenchyme during the early bud stage, they were absent in dental papilla or pulp at later stages. Sema3A mRNAs were observed in the dental epithelium including the cervical loops and a prominent expression was also seen in alveolar bone. Interestingly, transcripts were absent from the mesenchymal dental follicle target area (future periodontal ligament) throughout the studied stages. CONCLUSION:The expression patterns of Sema3A indicate that it may control the timing and patterning of the incisor innervation. In particular, Sema3A appears to regulate innervation of the periodontal ligament, while nerve penetration into the incisor dental pulp appears not to be dependent on Sema3A. Moreover, Sema3A may regulate the functions of cervical loops and the development of alveolar bone. Future study with Sema3A deficient mice will help to elucidate the putative neuronal and non-neuronal functions of Sema3A in incisor tooth development.
journal_name
Acta Odontol Scandjournal_title
Acta odontologica Scandinavicaauthors
Moe K,Shrestha A,Kvinnsland IH,Luukko K,Kettunen Pdoi
10.3109/00016357.2011.600717subject
Has Abstractpub_date
2012-05-01 00:00:00pages
184-9issue
3eissn
0001-6357issn
1502-3850journal_volume
70pub_type
杂志文章abstract::The aim of this study was to evaluate the caries-preventive effect of an oral health program for preschool children living in a multicultural, low socio-economic area. In total, 804 2-year-old children were invited and recalled every 3rd month to an outreach facility for parent education and toothbrushing instruction....
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350510019900
更新日期:2005-06-01 00:00:00
abstract::Three groups of extracted human teeth were sectioned longitudinally into experimental and control halves. The enamel surfaces of the three groups of teeth were pretreated with 37% H3PO4 for 1 min, 0.5 M NaClO3 for 2 h, or water rinsing for 10 min. The experimental halves of the three groups received an application of ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359609003538
更新日期:1996-10-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to analyze the clinicopathological and immunohistochemical features of oral papillomas. MATERIALS AND METHODS:Biopsies of oral papillomas analyzed in the laboratory between 1996-2012 were extracted from the database and used to conduct this retrospective review. The following clinic...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.996186
更新日期:2015-01-01 00:00:00
abstract::Candida fungi are frequent in the oral cavity, especially in denture wearers. The infection can cause serious complications in elderly or debilitated subject. The present experimental group consisted of 81 female psychiatric patients (35--91 years of age). In addition to a clinical examination, smears from the palate,...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357909004708
更新日期:1979-01-01 00:00:00
abstract::The aim of the study was to evaluate the efficacy of plaque removal of three different toothbrushes on mentally disabled children in two different age groups. A manual triple-headed brush (SuperBrush; Dento Co. AS [junior, regular]) compared with a new manual toothbrush (CrossAction; Oral-B [35 compact, 40 regular]) a...
journal_title:Acta odontologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/00016350410010054
更新日期:2004-12-01 00:00:00
abstract::Ceramic inlays offer a good alternative to posterior composites, which still show a high polymerization shrinkage. The thin cement layer will reduce the total amount of shrinkage and probably result in a better marginal adaptation and decreased marginal leakage. Fired feldspathic ceramic inlays cemented with either a ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359409027588
更新日期:1994-06-01 00:00:00
abstract::The enzyme beta-glucuronidase (E.C. 3.2.1.31.) has been studied in developing teeth and bone of Sprague-Dawley rats and Macaque monkeys (Macaca Irus) by means of histochemistry using naphthol-AS-BI-beta-D-glucuronide as substrate and hexazotized pararosanilin as coupling reagent. Since beta-glucuronidase is sensitive ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357509026357
更新日期:1975-01-01 00:00:00
abstract::Maxillary incisor lingual fossa depth was measured on casts of East Greenland Eskimo dentitions. No directional side asymmetry was found. The present study is the only which shows mean lingual fossa depth to be significantly deeper in the female than in the male. Larger incisor strength in the females is functional as...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358209019818
更新日期:1982-01-01 00:00:00
abstract:INTRODUCTION:The aim of this study is to compare the root canal transportation with the PathFile-ProTaper recommended protocol, PathFile-ProTaper modified protocol and stainless steel K-flexofiles. METHODS:Forty-five ISO 15, 0.02 taper S-shaped Endo Training Blocks were divided randomly into three groups of 15 each an...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2013.805430
更新日期:2014-01-01 00:00:00
abstract::Qualitative and quantitative features of mammalian tooth enamel structure are increasingly being used in taxonomic and phylogenetic analyses, although the variability shown by these traits has not received adequate consideration. This study evaluates the variability displayed by nine quantitative parameters in deep, i...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358709094349
更新日期:1987-02-01 00:00:00
abstract:OBJECTIVE:To determine if the differing contrast resolution of various LCD monitors affects the reliability or accuracy of measurements of proposed implant sites. MATERIALS AND METHODS:Edentulous areas of human dry skulls were marked with radiopaque markers in order to standardize the plane of the transverse cross-sec...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2012.741709
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVES:The present study addresses the effect of fluoride and sodium lauryl sulphate content of toothpaste on oral epithelial cells in vivo conditions. SUBJECTS AND METHOD:Forty volunteers were assigned into two experimental groups, each of them applying the different brand of toothpaste. Every group has been usin...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2019.1577988
更新日期:2019-07-01 00:00:00
abstract::Fluorescent microspheres (FM) were used to visualize and semi-quantify blood flow in the temporomandibular joint (TMJ) during experimental unilateral traumatic occlusion of the maxillary and mandibular molar teeth in 30 young rats. At different postoperative observation periods varying from 1 to 30 days FM were inject...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359309040580
更新日期:1993-10-01 00:00:00
abstract::In a Finnish rural population 79.0% of 233 persons had the cusp of Carabelli in first upper molars. Of these 20% showed "positive cusps" and 59% "negative cusps". The occurrence of the structure was bilateral with varying degrees of asymmetry, but if there was no structure on one side of the jaw, the other never showe...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357509027561
更新日期:1975-01-01 00:00:00
abstract::Errors in questionnaire surveys are usually of one of two sources: non-responses or incorrect answers. The aim was to investigate the validity of a questionnaire survey and to estimate the respective bias of these answers. Of 9,283 subjects selected to receive a questionnaire by post, 3,949 (43%) responded, and, of th...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163599428643
更新日期:1999-10-01 00:00:00
abstract::This in vitro study evaluated curing depths of a universal hybrid resin composite with two viscosities (Tetric Ceram and Tetric Flow) after curing with 6 different quartz tungsten halogen and light-emitting diode curing units. Irradiance (light intensity) of the curing units varied between 200 and 700 mW/cm2. The curi...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350410006905
更新日期:2004-04-01 00:00:00
abstract:OBJECTIVE:Previous results regarding human sex chromosome aneuploidies have shown that the X and Y chromosomes affect tooth size and morphology. This study looked for the effect of sex chromosome deficiency on permanent tooth crown heights. MATERIALS AND METHODS:The material, from the Finnish KVANTTI Research Project,...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.921327
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate the plaque pH level and ureolytic activity among children and adults of Karen Hill tribes. METHODS:Thirty-four children aged 6-10 years and 46 adults aged 20-38 years were interviewed regarding oral hygiene practices, sucrose intake and betel chewing. Caries experience ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2013.794952
更新日期:2014-04-01 00:00:00
abstract::The present study describes a Swedish family in which the mother and her son were affected with signs of popliteal pterygium syndrome (PPS, OMIM 119500). Both individuals had bilateral complete cleft lip and palate, oral synechiae, paramedian pits on the lower lip, toe syndactyly and a piece of triangular skin overgro...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163500429334
更新日期:2000-04-01 00:00:00
abstract:OBJECTIVE:This paper focuses on clinical responses after 7 days of oral exposure to two resin-based materials as desensitizing agents compared to a fluoride varnish and on morphological and analytical study as a means to elucidate the mechanism of action. MATERIALS AND METHODS:The elemental composition of Vertise™ Flo...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2012.700063
更新日期:2013-05-01 00:00:00
abstract::The adsorption onto silicon oxide surfaces from water and 0.1 M acetate buffer containing 10% parotid saliva at 25 degrees C and 35 degrees C and at pH 6 was monitored in situ using ellipsometry. The silicon oxide surface was used as a model for dental enamel. The adsorption kinetics and the reversibility on rinsing w...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359109005920
更新日期:1991-10-01 00:00:00
abstract:OBJECTIVE:The main goal of periodontal treatment is to control infection and, thereby, curb disease progression. Recent studies have suggested that the use of a laser as an adjunct to scaling and root planing (SRP) might improve the effectiveness of conventional periodontal treatment. The aim of this study was to evalu...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.3109/00016357.2014.898088
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:Zirconia implant abutments have gained a much broader clinical use over the past few years. The aim of the present study was to assess the clinical performance of a pre-fabricated zirconium dioxide implant abutment for single-tooth replacement in the posterior region. MATERIALS AND METHODS:Forty implants of ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2013.863970
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:Our aim was to assess the association between mandibular asymmetry and sagittal and transverse occlusal asymmetry in young adult males with class III malocclusion. Our hypotheses were that (1) mandibular asymmetry increases with increasing mandibular length and (2) occlusal asymmetry is correlated with mandib...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016350903460182
更新日期:2010-05-01 00:00:00
abstract::The purpose was to study differences in the caries increment rate as influenced by various sugars. The trial involved almost complete substitution of sucrose (S) by fructose (F) or xylitol (X) during a period of 2 years. There were no significant initial differences as to caries status between the prospective sugar gr...
journal_title:Acta odontologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00016357608997711
更新日期:1976-01-01 00:00:00
abstract:OBJECTIVE:To investigate the associations between oral sugar clearance and the prevalence of dental decay. MATERIAL AND METHODS:A total of 92 (44 F, 48 M) 71-year-old subjects in Goteborg, Sweden were consecutively chosen from a representative cohort study. The subjects were examined for: 1) caries-related status, 2) ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350802378647
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of the color change of hybrid light-emitting diode (LED) and low-intensity infrared diode laser devices for activating dental bleaching and to verify the occurrence of a color regression with time. MATERIAL AND METHODS:A total of 180 specimens obtained from human premolars were ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2010.549503
更新日期:2011-05-01 00:00:00
abstract::The aim was to describe the macroscopic and microscopic findings of areas with radiologic erosions in the human temporomandibular joint. An autopsy material of 40 human joints, removed as blocks, was examined with tomography, and an erosion was found in 37 areas. A macroscopic and a microscopic examination focused on ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359209012751
更新日期:1992-04-01 00:00:00
abstract::In a previous paper it was maintained that the effect of the permanent use of an anterior partial bite-raising splint was an intrusion of the front teeth and an eruption of the others. However, the effect might have been merely a change in the inclination of the front teeth. The present study comprised the same materi...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358309162340
更新日期:1983-10-01 00:00:00
abstract:OBJECTIVE:The clinical features of the early stages of bisphosphonate-related osteonecrosis of the jaw (BRONJ) in patients with breast cancer remain unclear. A retrospective cohort study was conducted of patients with breast cancer who received intravenous bisphosphonate (BP) treatment in a single center in order to cl...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.887772
更新日期:2014-11-01 00:00:00