Abstract:
OBJECTIVE:Local anesthetics are the most commonly used drugs in dentistry, with a wide range of effects, including antimicrobial activity. High antimicrobial effects have recently been reported on oral microbes from articaine hydrochloride, revealed by the minimum inhibitory concentration and minimal bactericidal concentration. Additionally, articaine has recently been used as an alkaline component in endodontic materials with a proposed antibacterial activity. However, the detailed mechanisms of action have not been discussed. MATERIAL AND METHODS:We determined the Langmuir surface pressure/molecular area isotherms of prokaryotic lipid monolayers, as well as the phospholipid phase transitions, by employing differential scanning calorimetry on unilamellar prokaryotic liposomes (bilayers). RESULTS:Articaine hydrochloride was found to interact with the prokaryotic membrane lipids in both monolayers and bilayers. An increase of the phospholipid molecular area of acidic glycerophospholipids as well as a decrease in phase transition temperature and enthalpy were found with increasing articaine hydrochloride concentration. The thermodynamic changes by adding articaine hydrochloride to prokaryotic membrane lipids are potentially related to the effects observed from antimicrobial peptides resulting from membrane insertion, aggregate composition, pore formation, and lysis. CONCLUSION:Interaction of articaine hydrochloride with prokaryotic membrane lipids is indicated. Hence, further research is necessary to gain insight into where these compounds exert their effects at the molecular level.
journal_name
Acta Odontol Scandjournal_title
Acta odontologica Scandinavicaauthors
Lygre H,Moe G,Nerdal W,Holmsen Hdoi
10.1080/00016350802443466subject
Has Abstractpub_date
2009-01-01 00:00:00pages
1-7issue
1eissn
0001-6357issn
1502-3850pii
904600655journal_volume
67pub_type
杂志文章abstract::The castability of two low-gold and two silver-palladium alloys was evaluated, using a Type III gold alloy as reference. Six castings from each alloy were subjected to a castability test, in which the marginal sharpness of simulated crowns--that is, the edge diameter--was used to assess the castability. The mean crown...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358609026569
更新日期:1986-06-01 00:00:00
abstract:OBJECTIVES:To study the dental fluorosis and caries in the permanent teeth of 12 to 13-year-old children in fluorosis-endemic areas; to assess the relationship between fluorosis and the fluoride content of the drinking water and the relationship between caries and the fluoride content of the water; finally, to analyze ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350510019991
更新日期:2005-10-01 00:00:00
abstract::Salivary mutans streptococci count, dental status, and related factors were studied in male industrial workers (age 38-65 years) with or without access to subsidized dental care. Altogether 315 subsidized workers and 168 controls without subsidy were compared. A prior questionnaire survey had shown that the two study ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163599428959
更新日期:1999-04-01 00:00:00
abstract::Recent studies on prenatal innervation of the jaws have shown that three separate main innervation paths, constituting three bilateral neural developmental fields (incisor field, canine/premolar field, molar field) exist in each jaw. In this communication the sequences in which the fields are innervated are indicated....
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::An interdisciplinary strategy based on a theoretical model for studying dental health was used to analyze the relevance of social and behavioral factors in the evaluation of dental health care for school children. The study comprised pupils who, after a total period of 5 years, differed in their experience with preven...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358409035248
更新日期:1984-04-01 00:00:00
abstract:OBJECTIVE:Since the properties of polymers can be influenced using electron-beam irradiation, the aim of this study was to investigate whether electron-beam post-curing can improve the mechanical properties of experimental denture base polymers. MATERIAL AND METHODS:Rectangular specimens of different experimental poly...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350701278781
更新日期:2007-06-01 00:00:00
abstract::The occurrence of different life-style patterns, including marital status, educational level, nutrition, tobacco and alcohol use, and frequency of physical activity, in patients with oral lichenoid reactions (OLR) in total or partial contact with amalgam fillings was examined. When compared with an age- and sex-matche...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359609006012
更新日期:1996-04-01 00:00:00
abstract::The aim of this study was to evaluate the effect of maternal use of chewing gums containing combinations of xylitol, sorbitol, chlorhexidine, and fluoride on salivary mutans streptococci (MS) counts and caries prevalence in the mothers' 3-year-old children. After screening 416 women with newborn babies, 173 mothers wi...
journal_title:Acta odontologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/00016350410001676
更新日期:2004-10-01 00:00:00
abstract::Three rosette strain gauges were attached to a fixed bilateral cantilevered crossarch maxillary bridge and one linear strain gauge to an attachment-retained removable partial denture (RPD), to study the functional deformation pattern in this combined reconstruction. The deformation under clinical conditions at maximum...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359309040584
更新日期:1993-12-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate the effect of three different irrigating solutions (17% EDTA, 10% citric acid and 2.5% NaOCl) and KTP laser irradiation on apical leakage using an electrochemical method. MATERIALS AND METHODS:Sixty extracted single-rooted human teeth with mature apices were instrume...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.3109/00016357.2011.615338
更新日期:2012-09-01 00:00:00
abstract::In a 5-year clinical trial it was observed that the marginal degradation of class-II amalgam restorations could be related to the bulk of the restoration. The association between the occlusal cavity depth and the marginal degradation was observed after 6 months and varied for the different types of alloy. Ridit scores...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359109005888
更新日期:1991-04-01 00:00:00
abstract:IMPORTANCE AND OBJECTIVE:Reactive Oxygen Species (ROS) are oxygen-derived molecules that are unstable and highly reactive. They are important signaling mediators of biological processes. In contrast, excessive ROS generation, defective oxidant scavenging or both have been implicated in the pathogenesis of several condi...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章,评审
doi:10.3109/00016357.2014.954267
更新日期:2015-02-01 00:00:00
abstract::The purpose was to study differences in the caries increment rate as influenced by various sugars. The trial involved almost complete substitution of sucrose (S) by fructose (F) or xylitol (X) during a period of 2 years. There were no significant initial differences as to caries status between the prospective sugar gr...
journal_title:Acta odontologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00016357608997711
更新日期:1976-01-01 00:00:00
abstract::The aim of the study was to evaluate the efficacy of plaque removal of three different toothbrushes on mentally disabled children in two different age groups. A manual triple-headed brush (SuperBrush; Dento Co. AS [junior, regular]) compared with a new manual toothbrush (CrossAction; Oral-B [35 compact, 40 regular]) a...
journal_title:Acta odontologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/00016350410010054
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVE:To summarize and review the literature on infant dental enucleation, a traditional remedial procedure prevalent mainly in East Africa. MATERIALS AND METHODS:Literature searches were made electronically using general and specialized search engines. The main search was performed through a systematic strategy i...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章,评审
doi:10.3109/00016357.2013.817603
更新日期:2014-04-01 00:00:00
abstract::A representative sample, 55%, of the patients treated endodontically by undergraduate students in a teaching clinic during the years 1963 to 1969 were reexamined 10-17 years later. Gutta-percha/Kloroperka-NO root fillings (282), classified as having surplus material at the time of treatment, were evaluated in follow-u...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358709098856
更新日期:1987-06-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to compare the cytotoxicity of four denture adhesives on human gingival fibroblast cells. MATERIALS AND METHODS:Immortalized human gingival fibroblasts were cultured with one of four different denture adhesives, Polident, Protefix, Staydent or Denfix-A, which was placed in inser...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.954266
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:The global pandemic of coronavirus disease-19, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is the latest hazard facing healthcare workers (HCW) including dental care workers (DCW). It is clear that the major mode of SARS-CoV-2 transmission is the airborne route, through inhalat...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2020.1810769
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:Color characteristics of the experimental resin composites were determined to know the influence of different refractive index (RI) on optical parameters. MATERIALS AND METHODS:Four experimental light-cured resin composites of the same shade but with different RI were used. The colorimetric values of the spe...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2011.600724
更新日期:2012-09-01 00:00:00
abstract::An epidemiological study was performed in 250 persons who five years previously had been treated with extensive metallic reconstructions. To gain representative information these persons were selected at random from three Local Social Insurance Offices in different parts of Sweden. Those person, who in a questionnaire...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358209025111
更新日期:1982-01-01 00:00:00
abstract::Mycotic flora was studied from the dentures and denture bearing mucosae of 39 persons who wore soft-lined (Molloplast B) mandibular dentures and heat-cured acrylic resin maxillary dentures. Fungal growth was detected in 85% of the mandibular dentures and in 44% of the maxillary dentures (p less than 0.001). On the man...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357709004655
更新日期:1977-01-01 00:00:00
abstract::Three composites, two microfilled (Heliosit and Silux) and one macrofilled (Prisma-Fil), were exposed to visible light from three different light units. The depth of the cure was estimated by measuring the length of the test specimen after removing the uncured material. The macrofilled composite cured to a greater dep...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358409041127
更新日期:1984-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to analyze the clinicopathological and immunohistochemical features of oral papillomas. MATERIALS AND METHODS:Biopsies of oral papillomas analyzed in the laboratory between 1996-2012 were extracted from the database and used to conduct this retrospective review. The following clinic...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.996186
更新日期:2015-01-01 00:00:00
abstract::Objective: This study aimed to survey periodontal status of Vietnamese patients with rheumatoid arthritis (RA) and investigates the association between periodontitis and RA in these patients.Materials and methods: We conducted a cross-sectional descriptive study on 150 RA patients and another 150 patients with osteoar...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2020.1747635
更新日期:2020-10-01 00:00:00
abstract::The aim of this study was to elucidate whether a premaxilla with a supernumerary tooth has additional dental abnormalities. The study does not include premaxillas with a mesiodens, only premaxillas with parasagittally located supernumerary teeth. Radiographs from eight children, followed from 1 year and 5 months to 11...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350310008634
更新日期:2004-02-01 00:00:00
abstract:INTRODUCTION:Certain oral manifestations signal progression of HIV disease among HAART naïve patients or an increase in the plasma HIV-1 RNA levels for those on treatment. Ranulas may be one of those manifestations. Therefore, this study describes the clinical features of patients who presented with ranulas including t...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2011.600709
更新日期:2012-03-01 00:00:00
abstract::Systemic retinoids are known to cause dryness of the mouth and changes in oral and lip mucosa. The purpose of this study was to evaluate changes in salivary variables during treatment with oral isotretinoin in patients receiving the drug for 3 months for cutaneous acne. Patients were examined 1 month after initiation ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359509006003
更新日期:1995-12-01 00:00:00
abstract::The frequency of temporomandibular disorders (TMDs) and radiologically observed abnormalities in the condyles of the temporomandibular joints (TMJs) of professional violin and viola players was investigated in 26 orchestra violinists/violists (VP group) and in their sex-, age-, and dentition-matched controls (C group)...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359509005951
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVE:To examine the initial viscosity and adhesive strength of modern denture adhesives in vitro. MATERIALS AND METHODS:Three cream-type denture adhesives (Poligrip S, Corect Cream, Liodent Cream; PGS, CRC, LDC) and three powder-type denture adhesives (Poligrip Powder, New Faston, Zanfton; PGP, FSN, ZFN) were use...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.913309
更新日期:2014-11-01 00:00:00
abstract::In this study, we examined the prevalence of specific (dental) phobia among a sample of the Icelandic population. In addition to dental anxiety we explored factors that could be related to dental anxiety. In the period 1972-73, a stratified sample of 1641 schoolchildren in Reykjavík was selected for a study on maloccl...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350310005844
更新日期:2003-10-01 00:00:00