Abstract:
OBJECTIVE:Polypharmacy is a common cause of xerostomia. This study aimed to investigate whether xerostomia could be an adverse drug event of mouthwashes, when they are used for longer than 2 weeks by patients taking polypharmacy. MATERIALS AND METHODS:This cross-sectional observational study included 120 hospitalized patients (60 middle-aged and 60 elderly patients), taking polypharmacy (≥4 drugs daily) and at risk of drug-induced xerostomia. Xerostomia was assessed by questioning participants. RESULTS:A total of 62.5% of patients complained of xerostomia. In the middle-aged group (mean age=44.0 (8.7) years; 35.0% women) xerostomia seemed independently associated to mouthwashes, at the limit of significance (OR=5.00, 95% CI=0.99-25.3, p=0.052). Active principles in mouthwashes were mainly quaternary ammonium compounds (91.9%). Mouthwashes may disturb the healthy balance of the biofilm moisturizing the oral mucosa. The biofilm contains mucins, salivary glycoproteins with oligosaccharides side chains able to sequester water and endogenous bacteria surrounded by a glycocalyx. Oral bacteria are fully susceptible to quaternary ammonium (chlorhexidine, hexetidine, cetylpyridinium chloride) and to other antiseptics used in mouthwashes, such as betain, resorcin, triclosan, essential oils and alcohol. However, caregivers currently recommend such dental plaque control products to patients suffering from xerostomia in order to reduce the risk of caries and periodontitis. CONCLUSION:This study is the first report that use of antiseptic mouthwashes for more than 2 weeks could worsen xerostomia in patients taking polypharmacy. Oral care protocols should avoid this iatrogenic practice, particularly when xerostomia alters the quality-of-life and worsens malnutrition.
journal_name
Acta Odontol Scandjournal_title
Acta odontologica Scandinavicaauthors
Chevalier M,Sakarovitch C,Precheur I,Lamure J,Pouyssegur-Rougier Vdoi
10.3109/00016357.2014.923108subject
Has Abstractpub_date
2015-05-01 00:00:00pages
267-73issue
4eissn
0001-6357issn
1502-3850journal_volume
73pub_type
杂志文章abstract:OBJECTIVE:To investigate the failure of 15 dental implants (Paragon/Zimmer) in relation to their surface quality. MATERIALS AND METHODS:The study comprised of 15 dental implants (7 mm D Advent Implant, 3.9 mm D apex design implant), which were followed from surgery to completion of prosthetic restorations. The implant...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2011.569507
更新日期:2011-11-01 00:00:00
abstract::Unfixed as well as glutaraldehyde-fixed pelleted cells from pure cultures of Streptococcus mutans subspecies sobrinus (B13) were embedded in glycolmethacrylate. Ultrathin were sections immunoperoxidase labelled with rabbit anti-S. mutans sobrinus gamma-globulin. It was found that unfixed specimens became labelled as p...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358209024071
更新日期:1982-01-01 00:00:00
abstract::Using dentist characteristics, our aim was to evaluate the reasons for replacements of fillings, the age of failed restorations in the posterior teeth of young adults, and replacement rates. Altogether 205 patient records from the Public Oral Health Service of the City of Vantaa, Finland were evaluated. Patient age wa...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163502762667333
更新日期:2002-12-01 00:00:00
abstract::Fifty-eight experimental resin restorations were performed in intact, human premolars, using different leakage-reducing restorative procedures. These were conventional acid-etching and acid-etching followed by cavity treatment with an intermediary layer of low-viscous resin or the dentin adhesive NPG-GMA/ethanol. The ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358909007710
更新日期:1989-10-01 00:00:00
abstract:OBJECTIVE:Color characteristics of the experimental resin composites were determined to know the influence of different refractive index (RI) on optical parameters. MATERIALS AND METHODS:Four experimental light-cured resin composites of the same shade but with different RI were used. The colorimetric values of the spe...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2011.600724
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:The aims of this study were to investigate the influence of deproteinization of dentin on the shear bond strength (SBS) mediated by eight dentin adhesives, and to evaluate the long-term durability of the SBSs. The hypotheses were that deproteinization of dentin would not affect the capacity for adherence, and...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350600633177
更新日期:2006-08-01 00:00:00
abstract::The aim of this study was to evaluate interdental caries incidence and progression in relation to the effect of antibacterial varnish treatments in schoolchildren anticipated at caries risk. After a screening procedure, 110 healthy children (8-10 years) with moderate and high counts of salivary mutans streptococci (MS...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163599428878
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVE:Sense of Coherence (SOC) has been associated with perceived oral health measures, but the contribution of SOC to clinical measures is still unclear. The aim of the present cross-sectional study was to evaluate the potential association between periodontal health outcomes, such as periodontal clinical paramete...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2016.1154601
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVE:This study investigated the association between dental fear and alcohol use disorder and smoking controlling for age, gender and attained level of education as well as anxiety and depressive disorders. MATERIALS AND METHODS:Nationally representative data on Finnish adults, 30 + years old (n = 5953), were gat...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2012.680902
更新日期:2013-03-01 00:00:00
abstract::Scanning electron microscopy was used to study the effect of cyclophosphamide (Cy) on molar development in 18 Sprague-Dawley rats from 15 to 48 days of age after birth. Doses of 30 mg/kg body weight of Cy dissolved in 1 ml 0.9% NaCl were given to the rats at 10 and 13 days of age. Eighteen control rats had injections ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359709115414
更新日期:1997-06-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to investigate the presence of symptoms and signs of temporomandibular disorders (TMD) in patients with tinnitus and to evaluate the effect of TMD treatment on tinnitus in a long-term perspective in comparison with a control group of patients on a waiting list. MATERIAL AND METHODS:O...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350500377842
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVE:A major aspect in evaluating the quality of dental materials is their physical properties. Their properties should be a best fit of the ones of dental hard tissues. Manufacturers give data sheets for each material. The properties listed are characterized by a specific value. This assumes (but does not prove) ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2013.878391
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:The aim of the current study was to investigate the presence of sulphate-reducing bacteria (SRB) in human saliva and correlate with oral and systemic conditions. METHODS:Saliva samples were collected from 118 patients and inoculated in 2 ml of modified Postgate's E medium culture. After 28 days of incubation...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2013.770163
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:The primary objective of this study was to investigate the association of systemic diseases, use of medications, allergies and tobacco habits with geographic tongue (GT) and fissured tongue (FT) lesions. The secondary objectives were to evaluate the clinical characteristics of tongue lesions and to compare t...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2015.1087046
更新日期:2016-01-01 00:00:00
abstract::The longevity of amalgam restorations in premolars and first and second molars in long-term recall patients has been calculated by means of survival analysis. The present retrospective longitudinal study includes information from 32 patients and their records over a time period of 17 years. The data were recorded by s...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359009005863
更新日期:1990-04-01 00:00:00
abstract::The influence of different clinical variables on the marginal degradation of amalgam restorations was studied in a clinical trial of class-II amalgam restorations. Seven Scandinavian dentists using 5 different alloys placed 468 restorations in 210 patients. The marginal degradation was scored on impressions of the res...
journal_title:Acta odontologica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.3109/00016359009029069
更新日期:1990-12-01 00:00:00
abstract::This study aimed at determining alveolar bone height in musicians playing wind instruments and non-wind instruments. Two hundred and forty-two subjects, 208 men and 34 women, from 3 national orchestras in Stockholm were examined in an intraoral full-mouth survey. The height of alveolar bone, registered by a computeriz...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358609026566
更新日期:1986-06-01 00:00:00
abstract::Qualitative and quantitative features of mammalian tooth enamel structure are increasingly being used in taxonomic and phylogenetic analyses, although the variability shown by these traits has not received adequate consideration. This study evaluates the variability displayed by nine quantitative parameters in deep, i...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358709094349
更新日期:1987-02-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of a chewing gum containing probiotic bacteria on gingival inflammation and the levels of selected inflammatory mediators in gingival crevicular fluid (GCF). MATERIAL AND METHODS:Forty-two healthy adults with moderate levels of gingival inflammation entered a double-blind placebo-co...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.1080/00016350802516170
更新日期:2009-01-01 00:00:00
abstract::There are many studies on the relationship between the tongue coating and halitosis, but few have evaluated the bacterial community present in the tongue coating. This study identified bacteria in the tongue coating in individuals with and without halitosis using 16S rRNA analysis. Forty subjects (mean age, 46.1 ± 15....
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2020.1754459
更新日期:2020-10-01 00:00:00
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journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2012.696695
更新日期:2013-05-01 00:00:00
abstract::The purpose of the present study was to determine the surface hydrophobicity of small oral spirochetes and to receive an impression of the molecular organization of the cell surfaces. Nine spirochete strains with one endoflagellum from each cell-end (1:2:1 spirochetes) and eight with two endoflagella from each cell-en...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359109041134
更新日期:1991-02-01 00:00:00
abstract::Tooth mortality and the frequency and distribution of endodontically treated teeth was studied in a Norwegian population group. The pre- and posttreatment situation was thus surveyed in 481 individuals with endodontic treatment. The middle aged and the female patients were overrepresented in the sample. At admittance ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357609026563
更新日期:1976-01-01 00:00:00
abstract::In a previous study, dentists reported very high scores for perceived physical workload, but only low to moderate scores for the musculoskeletal system. This is difficult to explain when other occupational groups in the dental services are compared, and is the main reason why the present study was performed. To measur...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350510019964
更新日期:2005-08-01 00:00:00
abstract::Three different methods were used to determine working and setting times of periodontal dressings. The Gillmore needle and the rheometer employed were not suitable for recording setting reactions. A penetration test was found applicable for determination of working and setting times for all three dressings although th...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357909004701
更新日期:1979-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare the fracture resistance of endodontically treated maxillary central incisors with incomplete crown ferrules after chewing simulation. MATERIAL AND METHODS:Forty caries-free maxillary central incisors were divided into 4 groups (n = 10). Endodontic treatment was performed....
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350500331120
更新日期:2006-02-01 00:00:00
abstract::The effect of extrinsic asthma on periodontal conditions was studied in a group of 30 asthmatic children. Clinical examination revealed that asthmatic children had more gingivitis than their healthy controls. The asthmatic children who received an inhaled corticosteroid as treatment had more severe gingivitis compared...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357909004680
更新日期:1979-01-01 00:00:00
abstract::The castability of two low-gold and two silver-palladium alloys was evaluated, using a Type III gold alloy as reference. Six castings from each alloy were subjected to a castability test, in which the marginal sharpness of simulated crowns--that is, the edge diameter--was used to assess the castability. The mean crown...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358609026569
更新日期:1986-06-01 00:00:00
abstract::Since acute osteoporosis is known to enhance bone remodeling and osteoid formation, it may also affect dentin apposition. We induced osteoporosis in 15-week-old Wistar rats by ovariectomy and dental caries by Streptococcus sobrinus infection in the presence of either a high sucrose (cariogenic) diet or a non-cariogeni...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359209012780
更新日期:1992-12-01 00:00:00
abstract::The adolescent growth of 212 randomly selected Swedish urban children has been investigated by using a graphical analysis of unsmoothed increments of height. The adolescent growth period has been divided into the pubertal spurt and the postpubertal period. On average, the pubertal spurt began at 10.0 years in girls, a...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358008997719
更新日期:1980-01-01 00:00:00