Short-term effect of chewing gums containing probiotic Lactobacillus reuteri on the levels of inflammatory mediators in gingival crevicular fluid.

Abstract:

OBJECTIVE:To investigate the effect of a chewing gum containing probiotic bacteria on gingival inflammation and the levels of selected inflammatory mediators in gingival crevicular fluid (GCF). MATERIAL AND METHODS:Forty-two healthy adults with moderate levels of gingival inflammation entered a double-blind placebo-controlled study design. The subjects were randomly assigned to one of three parallel arms: Group A/P was given one active and one placebo gum daily, Group A/A received two active chewing gums, and Group P/P two placebo gums. The chewing gums contained two strains of Lactobacillus reuteri: ATCC 55730 and ATCC PTA 5289 (1 x 10(8) CFU/gum, respectively). The subjects were instructed to chew the gums for 10 min over the course of 2 weeks. Bleeding on probing (BOP) and GCF sampling were conducted at baseline and after 1, 2 and 4 weeks. The levels of IL-1beta, TNF-alpha, IL-6, IL-8 and IL-10 were determined using luminex technology and multiplex immunoassay kits. RESULTS:BOP improved and GCF volume decreased in all groups during the chewing period, but the results were statistically significant (p<0.05) only in Groups A/P and A/A. The levels of TNF-alpha and IL-8 decreased significantly (p<0.05) in Group A/A compared with baseline after 1 and 2 weeks, respectively. A non-significant decreasing tendency was also observed concerning IL-1beta during the chewing period. The levels of IL-6 and IL-10 were unaffected in all groups after 1 and 2 weeks. CONCLUSIONS:The reduction of pro-inflammatory cytokines in GCF may be proof of principle for the probiotic approach combating inflammation in the oral cavity.

journal_name

Acta Odontol Scand

authors

Twetman S,Derawi B,Keller M,Ekstrand K,Yucel-Lindberg T,Stecksen-Blicks C

doi

10.1080/00016350802516170

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

19-24

issue

1

eissn

0001-6357

issn

1502-3850

pii

905073120

journal_volume

67

pub_type

杂志文章,随机对照试验
  • Bodily labializing lateral incisors: 3D analysis using finite element method.

    abstract:AIM:Among all tooth types and movements, bodily labializing the upper lateral incisors is a challenging one. The main goal of this study is to introduce and analyze a method to labialize palatally erupted lateral incisors. MATERIALS AND METHODS:Five three dimensional finite element models were designed in SolidWorks 2...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357.2012.700059

    authors: Geramy A

    更新日期:2013-05-01 00:00:00

  • Three-year comparison of fired ceramic inlays cemented with composite resin or glass ionomer cement.

    abstract::Ceramic inlays offer a good alternative to posterior composites, which still show a high polymerization shrinkage. The thin cement layer will reduce the total amount of shrinkage and probably result in a better marginal adaptation and decreased marginal leakage. Fired feldspathic ceramic inlays cemented with either a ...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016359409027588

    authors: Aberg CH,van Dijken JW,Olofsson AL

    更新日期:1994-06-01 00:00:00

  • Odontogenic infections: an 8-year epidemiologic analysis in a dental emergency outpatient care unit.

    abstract:OBJECTIVES:The purpose of this investigation was to analyze epidemiological patterns, clinical features and the management of odontogenic infections in patients undergoing treatment in a dental emergency outpatient care unit. STUDY DESIGN:A retrospective analysis of 58 161 case records of patients presenting to an eme...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357.2012.696694

    authors: Cachovan G,Phark JH,Schön G,Pohlenz P,Platzer U

    更新日期:2013-05-01 00:00:00

  • Computerized cephalometrics.

    abstract::A method to analyse cephalometric radiographs with the help of a computer has been described. With the system a cephalometric radiograph can be analysed and the results compared to corresponding analyses of individuals with ideal occlusion. The results can also be visualized as schematic figures of the patients. The c...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357809029087

    authors: Bergin R,Hallenberg J,Malmgren O

    更新日期:1978-01-01 00:00:00

  • Effect of the ultrasonic insertion technique on the seating of composite inlays.

    abstract::The seating of MOD composite inlays was determined before and after cementation with one of three cements of different viscosities. The seating was determined by measuring the axial discrepancy. Inlays were seated by strong finger pressure or by the ultrasonic insertion (USI) technique. The axial discrepancy of luted ...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016359409096376

    authors: Peutzfeldt A

    更新日期:1994-02-01 00:00:00

  • Effect of body weight in the pathogenesis of ligature-induced periodontal disease in Wistar rats.

    abstract:OBJECTIVE:The aim of this study was to compare ligature-induced alveolar bone loss between obese and non-obese rats. MATERIAL AND METHODS:Thirty female Wistar rats were randomly divided into two groups: a test group comprising 14 rats fed with a "cafeteria diet" for 120 days in order to gain weight and a control group...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016350802004672

    authors: Simch RP,Gaio EJ,Rosing CK

    更新日期:2008-06-01 00:00:00

  • Influence of cavity depth on marginal degradation of amalgam restorations.

    abstract::In a 5-year clinical trial it was observed that the marginal degradation of class-II amalgam restorations could be related to the bulk of the restoration. The association between the occlusal cavity depth and the marginal degradation was observed after 6 months and varied for the different types of alloy. Ridit scores...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016359109005888

    authors: Jokstad A

    更新日期:1991-04-01 00:00:00

  • The validity of different display monitors in the assessment of dental implant site dimensions in cone beam computed tomography images.

    abstract:OBJECTIVE:To determine if the differing contrast resolution of various LCD monitors affects the reliability or accuracy of measurements of proposed implant sites. MATERIALS AND METHODS:Edentulous areas of human dry skulls were marked with radiopaque markers in order to standardize the plane of the transverse cross-sec...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357.2012.741709

    authors: Al-Ekrish AA,Ekram MI,Al Faleh W,Alkhader M,Al-Sadhan R

    更新日期:2013-09-01 00:00:00

  • Association between mandibular asymmetry and occlusal asymmetry in young adult males with class III malocclusion.

    abstract:OBJECTIVE:Our aim was to assess the association between mandibular asymmetry and sagittal and transverse occlusal asymmetry in young adult males with class III malocclusion. Our hypotheses were that (1) mandibular asymmetry increases with increasing mandibular length and (2) occlusal asymmetry is correlated with mandib...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016350903460182

    authors: Staudt CB,Kiliaridis S

    更新日期:2010-05-01 00:00:00

  • Oral retention and discoloration tendency from a chlorhexidine mouth rinse.

    abstract::Individual differences in tooth discoloration have been observed after using chlorhexidine mouth rinses. To study the correlation between retention of chlorhexidine and the discoloration tendency, two groups, 'stainers' and 'non-stainers', were selected. The following parameters were tested: initial retention of chlor...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016358309162323

    authors: Solheim H,Roksvaag P,Eriksen HM,Nordbø H

    更新日期:1983-08-01 00:00:00

  • Electron immunoperoxidase stainings in sections of unfixed pure cultures of Streptococcus mutans.

    abstract::Unfixed as well as glutaraldehyde-fixed pelleted cells from pure cultures of Streptococcus mutans subspecies sobrinus (B13) were embedded in glycolmethacrylate. Ultrathin were sections immunoperoxidase labelled with rabbit anti-S. mutans sobrinus gamma-globulin. It was found that unfixed specimens became labelled as p...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016358209024071

    authors: Berthold P,Berthold CH,Nord CE

    更新日期:1982-01-01 00:00:00

  • Dye staining gap test: an alternative method for assessing marginal gap formation in composite restorations.

    abstract:OBJECTIVE:The aim of this study was to evaluate and compare marginal adaptation of composite restorations assessed by a dye staining method and by scanning electron microscopy (SEM) analysis. MATERIAL AND METHODS:Twenty bovine incisors were selected and ground flat to expose dentin. Two cylindrical cavities were prepa...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016350500474565

    authors: Caroline Bruschi Alonso R,Maria Correr G,Gonçalves Cunha L,Flávia Sanches Borges A,Maria Puppin-Rontani R,Alexandre Coelho Sinhoreti M

    更新日期:2006-06-01 00:00:00

  • Antiseptic mouthwashes could worsen xerostomia in patients taking polypharmacy.

    abstract:OBJECTIVE:Polypharmacy is a common cause of xerostomia. This study aimed to investigate whether xerostomia could be an adverse drug event of mouthwashes, when they are used for longer than 2 weeks by patients taking polypharmacy. MATERIALS AND METHODS:This cross-sectional observational study included 120 hospitalized ...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357.2014.923108

    authors: Chevalier M,Sakarovitch C,Precheur I,Lamure J,Pouyssegur-Rougier V

    更新日期:2015-05-01 00:00:00

  • Effect of therapeutic jaw exercise on temporomandibular disorders in individuals with chronic whiplash-associated disorders.

    abstract:OBJECTIVE:The aim of this study was to investigate the effect of a specific therapeutic jaw exercise on the temporomandibular disorders of patients with chronic whiplash-associated disorders. MATERIAL AND METHODS:Ninety-four consecutive patients with whiplash-related conditions were referred to and accepted for a trea...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/00016350600825310

    authors: Klobas L,Axelsson S,Tegelberg A

    更新日期:2006-11-01 00:00:00

  • Selection of criteria for assessment of occlusal acceptability.

    abstract::There is no general agreement on criteria that could be applied to distinguish between orthodontically acceptable and non-acceptable occlusions after the completion of dental development. The aim of the present study was to analyse morphological and functional features that could be used as an index to define an accep...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/000163502753740188

    authors: Svedström-Oristo AL,Pietilä T,Pietilä I,Helenius H,Peutzfeldt P,Varrela J

    更新日期:2002-06-01 00:00:00

  • Cross-sectional evaluation of post-operative pain and flare-ups in endodontic treatments using a type of rotary instruments.

    abstract:AIM:The purpose of this clinical study was to evaluate the general incidence of post-operative pain and flare-ups in patients who were endodontically treated by two endodontics specialists using rotary instruments (Hero 642, Micro Mega, France) with the same treatment protocol. METHODS:Records of 382 teeth belonging t...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357.2012.715199

    authors: Tanalp J,Sunay H,Bayirli G

    更新日期:2013-05-01 00:00:00

  • Clinical variables affecting the marginal degradation of amalgam restorations.

    abstract::The influence of different clinical variables on the marginal degradation of amalgam restorations was studied in a clinical trial of class-II amalgam restorations. Seven Scandinavian dentists using 5 different alloys placed 468 restorations in 210 patients. The marginal degradation was scored on impressions of the res...

    journal_title:Acta odontologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.3109/00016359009029069

    authors: Jokstad A,Mjör IA

    更新日期:1990-12-01 00:00:00

  • Characteristics of the early stages of intravenous bisphosphonate-related osteonecrosis of the jaw in patients with breast cancer.

    abstract:OBJECTIVE:The clinical features of the early stages of bisphosphonate-related osteonecrosis of the jaw (BRONJ) in patients with breast cancer remain unclear. A retrospective cohort study was conducted of patients with breast cancer who received intravenous bisphosphonate (BP) treatment in a single center in order to cl...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357.2014.887772

    authors: Matsuo A,Hamada H,Kaise H,Chikazu D,Yamada K,Kohno N

    更新日期:2014-11-01 00:00:00

  • Translation and validation of the Swedish version of the Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ) for adolescents.

    abstract:OBJECTIVE:The Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ) is an instrument developed for assessment of orthodontic aspects of oral health-related quality of life (OHRQoL). This study aimed to translate and validate the Swedish version of PIDAQ for use in Swedish adolescents 12-19 years of age. MATER...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016357.2020.1823014

    authors: Göranson E,Norevall LI,Bågesund M,Dimberg L

    更新日期:2020-10-07 00:00:00

  • Infant dental enucleation: A literature review on a traditional remedial practice in East Africa.

    abstract:OBJECTIVE:To summarize and review the literature on infant dental enucleation, a traditional remedial procedure prevalent mainly in East Africa. MATERIALS AND METHODS:Literature searches were made electronically using general and specialized search engines. The main search was performed through a systematic strategy i...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.3109/00016357.2013.817603

    authors: Barzangi J,Unell L,Söderfeldt B,Arnrup K

    更新日期:2014-04-01 00:00:00

  • Fluoride uptake in enamel and dentin surfaces exposed to a fluoride-containing amalgam in vitro. a proton microprobe analysis.

    abstract::Proton microprobe analysis was used to determine the fluoride concentrations in enamel and dentin surfaces exposed to a fluoride-containing and a conventional amalgam in vitro. After seven weeks of exposure, a considerable fluoride uptake was demonstrated from the fluoride-containing amalgam. The fluoride deposition w...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016358009033594

    authors: Tveit AB,Lindh U

    更新日期:1980-01-01 00:00:00

  • Ranulas: possible signs for HIV/AIDS? 1 year Ugandan descriptive study.

    abstract:INTRODUCTION:Certain oral manifestations signal progression of HIV disease among HAART naïve patients or an increase in the plasma HIV-1 RNA levels for those on treatment. Ranulas may be one of those manifestations. Therefore, this study describes the clinical features of patients who presented with ranulas including t...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357.2011.600709

    authors: Kamulegeya A,Okello SM

    更新日期:2012-03-01 00:00:00

  • The relationship between turbidity of mouth-rinsed water and oral health status.

    abstract:OBJECTIVES:The purpose of this study was to examine the relationship between turbidity of mouth rinsed water and oral health status such as dental and periodontal conditions, oral hygiene status, flow rate of saliva and oral bacteria. MATERIALS AND METHODS:Subjects were 165 patients who visited the Dental Hospital, To...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357.2011.654258

    authors: Takeuchi S,Ueno M,Takehara S,Pham TA,Hakuta C,Morishima S,Shinada K,Kawaguchi Y

    更新日期:2013-01-01 00:00:00

  • Expression of Wnt3a, Wnt10b, β-catenin and DKK1 in periodontium during orthodontic tooth movement in rats.

    abstract:OBJECTIVE:To investigate the expression of Wnt3a, Wnt10b, β-catenin and DKK1 in the periodontal ligament (PDL) during orthodontic tooth movement (OTM) in rats. MATERIALS AND METHODS:Nickel-titanium closed-coil springs were used to deliver an initial 50 g mesial force to the left maxillary first molars in 30 rats. The ...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357.2015.1090011

    authors: Lu J,Duan Y,Zhang M,Wu M,Wang Y

    更新日期:2016-01-01 00:00:00

  • A four-year longitudinal study of palatal plate therapy in children with Down syndrome: effects on oral motor function, articulation and communication preferences.

    abstract::The orofacial function in 20 children with Down syndrome was evaluated after 4 years of palatal plate therapy in 9 of the children (PPG); the remaining 11 were untreated age-matched controls (CG). All 20 children had received continuous orofacial physical therapy from their speech therapist during the treatment period...

    journal_title:Acta odontologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1080/ode.61.1.39.46

    authors: Carlstedt K,Henningsson G,Dahllöf G

    更新日期:2003-02-01 00:00:00

  • Some effects of bone meal supplemented diet on bone and teeth of growing rats.

    abstract::Bone meal (containing 500 ppm F) was added to the diet of growing rats in an amount corresponding to that recommended ingested by children. Addition of bone meal did not influence body weight increment, or growth and ash content of bone and teeth. Fluoride in bone and teeth increased as compared to control animals, bu...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016358109162295

    authors: Rasmussen P,Wesenberg GR

    更新日期:1981-01-01 00:00:00

  • An index for evaluating wear of teeth.

    abstract::An index for evaluation of dental wear based on Ryge's system comprising three satisfactory and two not acceptable categories was tested in two different age groups of individuals with brain damage. Group 1 consisted of 12 individuals, 3 women and 9 men, with a mean age of 34.5 years. Group 2 consisted of 13 individua...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016358709096359

    authors: Oilo G,Dahl BL,Hatle G,Gad AL

    更新日期:1987-10-01 00:00:00

  • Causal relation between malocclusion and periodontal health.

    abstract::The purpose of this 20-year follow-up study was to assess whether persistent traits of morphologic malocclusion imply an increased risk of periodontal disease. In 1965-66 malocclusion was recorded in 176 adolescents who were re-examined in 1986-87 at the age of 33-39 years. Markedly healthier periodontal conditions we...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016358909007705

    authors: Helm S,Petersen PE

    更新日期:1989-08-01 00:00:00

  • Incidence and prevalence of temporomandibular joint pain and dysfunction. A one-year prospective study of university students.

    abstract:OBJECTIVE:The aims of this study were to investigate the incidence and recovery of temporomandibular joint (TMJ) pain and dysfunction during a 1-year period, and to examine factors associated with TMJ signs and symptoms. MATERIAL AND METHODS:The study population comprised 371 dental students examined at the start of e...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016350601083554

    authors: Marklund S,Wänman A

    更新日期:2007-04-01 00:00:00

  • The influence of kinematics of engine-driven nickel-titanium instruments on root canal shape assessed by micro-computed tomography: a systematic review.

    abstract:AIM:To evaluate if the kinematics of engine-driven instruments affect the root canal shape. METHOD:The systematic review was registered in PROSPERO (CRD 42017077043). A broad search was performed for articles published before 26 September 2018 in the electronic databases: pubmed, scopus, web of science and Lilacs usin...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016357.2019.1570331

    authors: Tavares SJO,Sarmento EB,Guimarães LDS,Antunes LAA,Antunes LS,Gomes CC

    更新日期:2019-07-01 00:00:00