Abstract:
OBJECTIVE:To investigate the effect of a chewing gum containing probiotic bacteria on gingival inflammation and the levels of selected inflammatory mediators in gingival crevicular fluid (GCF). MATERIAL AND METHODS:Forty-two healthy adults with moderate levels of gingival inflammation entered a double-blind placebo-controlled study design. The subjects were randomly assigned to one of three parallel arms: Group A/P was given one active and one placebo gum daily, Group A/A received two active chewing gums, and Group P/P two placebo gums. The chewing gums contained two strains of Lactobacillus reuteri: ATCC 55730 and ATCC PTA 5289 (1 x 10(8) CFU/gum, respectively). The subjects were instructed to chew the gums for 10 min over the course of 2 weeks. Bleeding on probing (BOP) and GCF sampling were conducted at baseline and after 1, 2 and 4 weeks. The levels of IL-1beta, TNF-alpha, IL-6, IL-8 and IL-10 were determined using luminex technology and multiplex immunoassay kits. RESULTS:BOP improved and GCF volume decreased in all groups during the chewing period, but the results were statistically significant (p<0.05) only in Groups A/P and A/A. The levels of TNF-alpha and IL-8 decreased significantly (p<0.05) in Group A/A compared with baseline after 1 and 2 weeks, respectively. A non-significant decreasing tendency was also observed concerning IL-1beta during the chewing period. The levels of IL-6 and IL-10 were unaffected in all groups after 1 and 2 weeks. CONCLUSIONS:The reduction of pro-inflammatory cytokines in GCF may be proof of principle for the probiotic approach combating inflammation in the oral cavity.
journal_name
Acta Odontol Scandjournal_title
Acta odontologica Scandinavicaauthors
Twetman S,Derawi B,Keller M,Ekstrand K,Yucel-Lindberg T,Stecksen-Blicks Cdoi
10.1080/00016350802516170subject
Has Abstractpub_date
2009-01-01 00:00:00pages
19-24issue
1eissn
0001-6357issn
1502-3850pii
905073120journal_volume
67pub_type
杂志文章,随机对照试验abstract:AIM:Among all tooth types and movements, bodily labializing the upper lateral incisors is a challenging one. The main goal of this study is to introduce and analyze a method to labialize palatally erupted lateral incisors. MATERIALS AND METHODS:Five three dimensional finite element models were designed in SolidWorks 2...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2012.700059
更新日期:2013-05-01 00:00:00
abstract::Ceramic inlays offer a good alternative to posterior composites, which still show a high polymerization shrinkage. The thin cement layer will reduce the total amount of shrinkage and probably result in a better marginal adaptation and decreased marginal leakage. Fired feldspathic ceramic inlays cemented with either a ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359409027588
更新日期:1994-06-01 00:00:00
abstract:OBJECTIVES:The purpose of this investigation was to analyze epidemiological patterns, clinical features and the management of odontogenic infections in patients undergoing treatment in a dental emergency outpatient care unit. STUDY DESIGN:A retrospective analysis of 58 161 case records of patients presenting to an eme...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2012.696694
更新日期:2013-05-01 00:00:00
abstract::A method to analyse cephalometric radiographs with the help of a computer has been described. With the system a cephalometric radiograph can be analysed and the results compared to corresponding analyses of individuals with ideal occlusion. The results can also be visualized as schematic figures of the patients. The c...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357809029087
更新日期:1978-01-01 00:00:00
abstract::The seating of MOD composite inlays was determined before and after cementation with one of three cements of different viscosities. The seating was determined by measuring the axial discrepancy. Inlays were seated by strong finger pressure or by the ultrasonic insertion (USI) technique. The axial discrepancy of luted ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359409096376
更新日期:1994-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare ligature-induced alveolar bone loss between obese and non-obese rats. MATERIAL AND METHODS:Thirty female Wistar rats were randomly divided into two groups: a test group comprising 14 rats fed with a "cafeteria diet" for 120 days in order to gain weight and a control group...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350802004672
更新日期:2008-06-01 00:00:00
abstract::In a 5-year clinical trial it was observed that the marginal degradation of class-II amalgam restorations could be related to the bulk of the restoration. The association between the occlusal cavity depth and the marginal degradation was observed after 6 months and varied for the different types of alloy. Ridit scores...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359109005888
更新日期:1991-04-01 00:00:00
abstract:OBJECTIVE:To determine if the differing contrast resolution of various LCD monitors affects the reliability or accuracy of measurements of proposed implant sites. MATERIALS AND METHODS:Edentulous areas of human dry skulls were marked with radiopaque markers in order to standardize the plane of the transverse cross-sec...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2012.741709
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:Our aim was to assess the association between mandibular asymmetry and sagittal and transverse occlusal asymmetry in young adult males with class III malocclusion. Our hypotheses were that (1) mandibular asymmetry increases with increasing mandibular length and (2) occlusal asymmetry is correlated with mandib...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016350903460182
更新日期:2010-05-01 00:00:00
abstract::Individual differences in tooth discoloration have been observed after using chlorhexidine mouth rinses. To study the correlation between retention of chlorhexidine and the discoloration tendency, two groups, 'stainers' and 'non-stainers', were selected. The following parameters were tested: initial retention of chlor...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358309162323
更新日期:1983-08-01 00:00:00
abstract::Unfixed as well as glutaraldehyde-fixed pelleted cells from pure cultures of Streptococcus mutans subspecies sobrinus (B13) were embedded in glycolmethacrylate. Ultrathin were sections immunoperoxidase labelled with rabbit anti-S. mutans sobrinus gamma-globulin. It was found that unfixed specimens became labelled as p...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358209024071
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate and compare marginal adaptation of composite restorations assessed by a dye staining method and by scanning electron microscopy (SEM) analysis. MATERIAL AND METHODS:Twenty bovine incisors were selected and ground flat to expose dentin. Two cylindrical cavities were prepa...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350500474565
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVE:Polypharmacy is a common cause of xerostomia. This study aimed to investigate whether xerostomia could be an adverse drug event of mouthwashes, when they are used for longer than 2 weeks by patients taking polypharmacy. MATERIALS AND METHODS:This cross-sectional observational study included 120 hospitalized ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.923108
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the effect of a specific therapeutic jaw exercise on the temporomandibular disorders of patients with chronic whiplash-associated disorders. MATERIAL AND METHODS:Ninety-four consecutive patients with whiplash-related conditions were referred to and accepted for a trea...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.1080/00016350600825310
更新日期:2006-11-01 00:00:00
abstract::There is no general agreement on criteria that could be applied to distinguish between orthodontically acceptable and non-acceptable occlusions after the completion of dental development. The aim of the present study was to analyse morphological and functional features that could be used as an index to define an accep...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163502753740188
更新日期:2002-06-01 00:00:00
abstract:AIM:The purpose of this clinical study was to evaluate the general incidence of post-operative pain and flare-ups in patients who were endodontically treated by two endodontics specialists using rotary instruments (Hero 642, Micro Mega, France) with the same treatment protocol. METHODS:Records of 382 teeth belonging t...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2012.715199
更新日期:2013-05-01 00:00:00
abstract::The influence of different clinical variables on the marginal degradation of amalgam restorations was studied in a clinical trial of class-II amalgam restorations. Seven Scandinavian dentists using 5 different alloys placed 468 restorations in 210 patients. The marginal degradation was scored on impressions of the res...
journal_title:Acta odontologica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.3109/00016359009029069
更新日期:1990-12-01 00:00:00
abstract:OBJECTIVE:The clinical features of the early stages of bisphosphonate-related osteonecrosis of the jaw (BRONJ) in patients with breast cancer remain unclear. A retrospective cohort study was conducted of patients with breast cancer who received intravenous bisphosphonate (BP) treatment in a single center in order to cl...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.887772
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:The Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ) is an instrument developed for assessment of orthodontic aspects of oral health-related quality of life (OHRQoL). This study aimed to translate and validate the Swedish version of PIDAQ for use in Swedish adolescents 12-19 years of age. MATER...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2020.1823014
更新日期:2020-10-07 00:00:00
abstract:OBJECTIVE:To summarize and review the literature on infant dental enucleation, a traditional remedial procedure prevalent mainly in East Africa. MATERIALS AND METHODS:Literature searches were made electronically using general and specialized search engines. The main search was performed through a systematic strategy i...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章,评审
doi:10.3109/00016357.2013.817603
更新日期:2014-04-01 00:00:00
abstract::Proton microprobe analysis was used to determine the fluoride concentrations in enamel and dentin surfaces exposed to a fluoride-containing and a conventional amalgam in vitro. After seven weeks of exposure, a considerable fluoride uptake was demonstrated from the fluoride-containing amalgam. The fluoride deposition w...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358009033594
更新日期:1980-01-01 00:00:00
abstract:INTRODUCTION:Certain oral manifestations signal progression of HIV disease among HAART naïve patients or an increase in the plasma HIV-1 RNA levels for those on treatment. Ranulas may be one of those manifestations. Therefore, this study describes the clinical features of patients who presented with ranulas including t...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2011.600709
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to examine the relationship between turbidity of mouth rinsed water and oral health status such as dental and periodontal conditions, oral hygiene status, flow rate of saliva and oral bacteria. MATERIALS AND METHODS:Subjects were 165 patients who visited the Dental Hospital, To...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2011.654258
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To investigate the expression of Wnt3a, Wnt10b, β-catenin and DKK1 in the periodontal ligament (PDL) during orthodontic tooth movement (OTM) in rats. MATERIALS AND METHODS:Nickel-titanium closed-coil springs were used to deliver an initial 50 g mesial force to the left maxillary first molars in 30 rats. The ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2015.1090011
更新日期:2016-01-01 00:00:00
abstract::The orofacial function in 20 children with Down syndrome was evaluated after 4 years of palatal plate therapy in 9 of the children (PPG); the remaining 11 were untreated age-matched controls (CG). All 20 children had received continuous orofacial physical therapy from their speech therapist during the treatment period...
journal_title:Acta odontologica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1080/ode.61.1.39.46
更新日期:2003-02-01 00:00:00
abstract::Bone meal (containing 500 ppm F) was added to the diet of growing rats in an amount corresponding to that recommended ingested by children. Addition of bone meal did not influence body weight increment, or growth and ash content of bone and teeth. Fluoride in bone and teeth increased as compared to control animals, bu...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358109162295
更新日期:1981-01-01 00:00:00
abstract::An index for evaluation of dental wear based on Ryge's system comprising three satisfactory and two not acceptable categories was tested in two different age groups of individuals with brain damage. Group 1 consisted of 12 individuals, 3 women and 9 men, with a mean age of 34.5 years. Group 2 consisted of 13 individua...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358709096359
更新日期:1987-10-01 00:00:00
abstract::The purpose of this 20-year follow-up study was to assess whether persistent traits of morphologic malocclusion imply an increased risk of periodontal disease. In 1965-66 malocclusion was recorded in 176 adolescents who were re-examined in 1986-87 at the age of 33-39 years. Markedly healthier periodontal conditions we...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358909007705
更新日期:1989-08-01 00:00:00
abstract:OBJECTIVE:The aims of this study were to investigate the incidence and recovery of temporomandibular joint (TMJ) pain and dysfunction during a 1-year period, and to examine factors associated with TMJ signs and symptoms. MATERIAL AND METHODS:The study population comprised 371 dental students examined at the start of e...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350601083554
更新日期:2007-04-01 00:00:00
abstract:AIM:To evaluate if the kinematics of engine-driven instruments affect the root canal shape. METHOD:The systematic review was registered in PROSPERO (CRD 42017077043). A broad search was performed for articles published before 26 September 2018 in the electronic databases: pubmed, scopus, web of science and Lilacs usin...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2019.1570331
更新日期:2019-07-01 00:00:00