Abstract:
OBJECTIVE:To investigate the expression of Wnt3a, Wnt10b, β-catenin and DKK1 in the periodontal ligament (PDL) during orthodontic tooth movement (OTM) in rats. MATERIALS AND METHODS:Nickel-titanium closed-coil springs were used to deliver an initial 50 g mesial force to the left maxillary first molars in 30 rats. The force was kept constant for 1, 3, 5, 7, 10 and 14 days until the animals were sacrificed. The right maxillary molars without force application served as control. Paraffin-embedded sections of the upper jaws were prepared for histological and immunohistochemical analyses to detect Wnt3a, Wnt10b, β-catenin and DKK1 expression in PDL. RESULTS:Wnt3a, Wnt10b, β-catenin and DKK1 were expressed on both the ipsilateral and contralateral sides of PDL in each group. After the application of orthodontic force, the expression of β-catenin and DKK1 was initially increased and then decreased on both sides, with maximal levels of expression at day 7 and day 10, respectively. On the compression side, Wnt3a and Wnt10b levels started to increase at day 5, while on the tension side, these two molecules began to increase at day 1. Furthermore, the expression levels of Wnt3a, Wnt10b, and β-catenin were much stronger on the tension side than on the compression side at any of the observation points, while DKK1 level was much higher on the compression side. CONCLUSION:Wnt3a, Wnt10b, β-catenin and DKK1 expression may be related to the periodontal tissue remodeling following the application of an orthodontic force in rats. These observations suggest that the Wnt/β-catenin signaling pathway may play a crucial role in periodontal tissue remodeling during OTM.
journal_name
Acta Odontol Scandjournal_title
Acta odontologica Scandinavicaauthors
Lu J,Duan Y,Zhang M,Wu M,Wang Ydoi
10.3109/00016357.2015.1090011subject
Has Abstractpub_date
2016-01-01 00:00:00pages
217-23issue
3eissn
0001-6357issn
1502-3850journal_volume
74pub_type
杂志文章abstract:OBJECTIVE:To examine the initial viscosity and adhesive strength of modern denture adhesives in vitro. MATERIALS AND METHODS:Three cream-type denture adhesives (Poligrip S, Corect Cream, Liodent Cream; PGS, CRC, LDC) and three powder-type denture adhesives (Poligrip Powder, New Faston, Zanfton; PGP, FSN, ZFN) were use...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.913309
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:Semaphorin 3A (Sema3A) is an essential chemorepellant controlling peripheral axon pathfinding and patterning, but also serves non-neuronal cellular functions. Incisors of rodent are distinctive from molars as they erupt continuously, have only one root and enamel is present only on the labial side. The aim of...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2011.600717
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to evaluate association between psychological factors, socio-demographic conditions, oral habits and anterior open bite in five-year-old preschool children. MATERIALS AND METHODS:A cross-sectional study was conducted with 764 pairs of children and parents/caregivers in presch...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2018.1472294
更新日期:2018-11-01 00:00:00
abstract::Twenty-four Long Evans/Turku rats were used to study the effect of prenatally increased oxygen tension on the mandibular condylar cartilage. Pregnant rats were exposed to increased oxygen tension in an air chamber for 14 days. The animals were returned to normal laboratory conditions after parturition. Three control a...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358609004737
更新日期:1986-10-01 00:00:00
abstract::Four different cements were used to assess the presence of slits at the cement/tooth or the cement/alloy interfaces using a tooth-crown model. The model consisted of ground sections of teeth and plane plates of silver/palladium alloy. The plates were fixed with bolts between two brass plates and with three different d...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::Our aim was to determine whether masseter muscle (M) and plasma (P) levels of prostaglandin E2 (PGE2) or leukotriene B4 (LTB4) are influenced by local glucocorticoid administration and whether such changes would be associated with corresponding changes in local pain or hyperalgesia. Eighteen patients with fibromyalgia...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163502753471970
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:To examine whether long-term utilization of dental care, treatment with fillings and crowns and persistent tooth loss between age 50 and 65 years associate with subsequent changes in OHRQoL from age 65 to 70 years. METHOD:In 1992, a census of 50-year-olds received invitation to participate in a questionnaire...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2018.1474249
更新日期:2018-11-01 00:00:00
abstract::The orofacial function in 20 children with Down syndrome was evaluated after 4 years of palatal plate therapy in 9 of the children (PPG); the remaining 11 were untreated age-matched controls (CG). All 20 children had received continuous orofacial physical therapy from their speech therapist during the treatment period...
journal_title:Acta odontologica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1080/ode.61.1.39.46
更新日期:2003-02-01 00:00:00
abstract:OBJECTIVE:Guided by the conceptual framework of Gilbert and co-workers, this study assesses satisfaction with oral health as reported by 65-year-olds in Sweden and Norway, the relationship of socio-demographic factors, clinical and subjective oral health indicators with satisfaction of oral health, and the consistency ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350902908780
更新日期:2009-01-01 00:00:00
abstract::The purpose of this study was to determine the sensitivity, specificity, positive and negative predictive values for Corah's Dental Anxiety Scale (DAS) and two modified versions of it (MDAS; MDAS/4). A questionnaire was mailed to a simple random sample of 1,190 25-year-old residents in the west of Norway in 1997. Half...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350050217091
更新日期:2000-12-01 00:00:00
abstract::The use of permanent magnets in orthodontic treatment has increased significantly over the past years, triggered by the introduction of rare earth magnetic alloys. Concerns about possible side effects have been expressed relating to their use in orthodontic treatment. In previous experimental studies evidence of a red...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359509005983
更新日期:1995-08-01 00:00:00
abstract::In the present investigation the microstructure and bonding between the wrought and cast elements of the post and core specimens were evaluated with respect to the preheating temperature of the investment. Clinically sized specimens were produced from one type III gold casting alloy in combination with two different w...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358209019819
更新日期:1982-01-01 00:00:00
abstract::A bacteriological investigation has been made in two cases of persistent periapical infections. Neither of the two infections responded to root canal therapy including penicillin or penicillin and erythromycin. Samples were taken aseptically for bacteriological examination through and root canals. Chloroform-washed, s...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358309162299
更新日期:1983-01-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to directly compare Carisolv and Papacarie regarding the volume of removed tissue (RT) and dentin mineral density (DMD) after excavation. MATERIALS AND METHODS:Twenty permanent molars were randomized into two groups where caries was excavated using Carisolv or Papacarie follo...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2017.1406614
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:Local anesthetics are the most commonly used drugs in dentistry, with a wide range of effects, including antimicrobial activity. High antimicrobial effects have recently been reported on oral microbes from articaine hydrochloride, revealed by the minimum inhibitory concentration and minimal bactericidal conce...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350802443466
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:Because of its good matching performance the VITA 3D-Master shade guide (3D) is frequently used for determination of tooth color. Numerous composites/ceramics are, however, available in VITA Classical (VC) shades only. The objective of this study was to investigate the possibility of performing a shade match...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2012.715197
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the smear layer removal and wettability of AH Plus sealer on root canal dentin treated with MA (maleic acid), MA + CTR (cetrimide) and MA + CTR + CHX (chlorhexidine) as final irrigating regimens. MATERIAL AND METHODS:For smear layer removal, 40 teeth were instrumented to size F4 and divided into ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2017.1402208
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the effects of various irrigating solutions and photoactivated disinfection (PAD) on the push-out bond strengths of fiber posts to root dentin. MATERIALS AND METHODS:Thirty-two human teeth were divided into eight groups, as follows: (1) irrigation with physiologic saline...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.906651
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To present a follow-up using the Dental Discomfort Questionnaire (DDQ) before and after the treatment of children, under the assumption that the number of toothache-related behaviors diminishes as a result of treatment, and to see whether this effect is related to the site of the carious teeth or to the treat...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350500264362
更新日期:2005-11-01 00:00:00
abstract::In Finland, adults born in 1961 or later were progressively entitled to subsidies for dental care from private practitioners during 1986-90, while at the same time having access to care in the Public Dental Service. The aim of this study was to compare the effects of attendance frequency of private dental care on trea...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163502753509473
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVE:This study aimed to perform the cross-cultural adaptation and validation of the NVS for Brazilian Portuguese. MATERIAL AND METHODS:Two hundred and fifty adults responded to the adapted version of the NVS, the Brazilian version of the Rapid Estimate of Adult Literacy in Dentistry (BREALD-30), ten questions of...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2018.1484511
更新日期:2018-11-01 00:00:00
abstract::Fixed prosthodontic work ordered by general dental practitioners was examined through registrations made in commercial dental laboratories. A comparison was made with similar data from student files on fixed prosthodontic treatment at the University Clinic in Bergen, Norway, which is located in the same geographic are...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359009005880
更新日期:1990-08-01 00:00:00
abstract::Twenty-seven gold crowns, removed from patients with problems such as diffuse pain and metallic taste, have been examined. The gold crowns were made of an ordinary casting gold alloy, type III. The crowns were built on amalgam cores or big amalgam fillings. Eight of these crowns had cracks beginning at the cervical ma...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358509064134
更新日期:1985-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:radioiodine treatment (I131) used to treat thyroid carcinomas produces side effects (sialadenitis, xerostomia, dysphagia and caries susceptibility) reflecting in a poor patient quality of life. This study aimed to evaluate the effect of I131 on salivary function and possible oral impairment. M...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2017.1399214
更新日期:2018-03-01 00:00:00
abstract::In a previous paper it was maintained that the effect of the permanent use of an anterior partial bite-raising splint was an intrusion of the front teeth and an eruption of the others. However, the effect might have been merely a change in the inclination of the front teeth. The present study comprised the same materi...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358309162340
更新日期:1983-10-01 00:00:00
abstract:OBJECTIVE:A 2-month randomized clinical trial (RCT) study comparing electric and manual toothbrushes used by residents in nursing homes showed significant reduction in plaque score for both groups. The aim of this follow up study was to study if the effect sustained in a longer perspective when toothbrushes were used a...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.1080/00016357.2017.1416166
更新日期:2018-05-01 00:00:00
abstract::Microleakage was studied in class-II cavities restored with a calcium hydroxide liner and an adhesive system combined with two different posterior composite resins. The restorations were exposed to repeated loading when immersed in dye solution. The teeth were cut, and microleakage along the cavity walls and into dent...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359109005915
更新日期:1991-08-01 00:00:00
abstract::The occurrence of different life-style patterns, including marital status, educational level, nutrition, tobacco and alcohol use, and frequency of physical activity, in patients with oral lichenoid reactions (OLR) in total or partial contact with amalgam fillings was examined. When compared with an age- and sex-matche...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359609006012
更新日期:1996-04-01 00:00:00
abstract:OBJECTIVE:Considering that patients' satisfaction is one of the most important goals in conducting removable dental prosthesis (RDP) therapy and the fact that there are many factors which influence this parameter, the present study aims to evaluate the expectation before and satisfaction after therapy with RDP in patie...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2012.654612
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the influence of coffee and red wine staining on tooth color during and after bleaching. MATERIALS AND METHODS:Blocks obtained from human molars were divided into 11 groups (n = 5) in accordance with the bleaching treatment-peroxide carbamide 10%, 15% or 20%-and in accor...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2013.771404
更新日期:2013-11-01 00:00:00