Primary nasopharyngeal non-Hodgkin's lymphoma: imaging patterns on MR imaging.

Abstract:

OBJECTIVES:To summarize the distinct imaging features of different subtypes of primary nasopharyngeal non-Hodgkin's lymphomas (NHLs). MATERIALS AND METHODS:Clinical data and magnetic resonance imaging findings of 71 patients with histologically proven primary nasopharyngeal NHLs were retrospectively reviewed. The tumor distribution, signal intensity, lesion texture, contrast enhancement properties, extra-chamber involvement, regional structure invasion, and cervical lymphadenopathy were evaluated and compared between different subtypes of NHLs. RESULTS:Of the patients, 70.4% had B-cell lymphomas; 64.8% had symmetrical and diffuse involvement of nasopharynx walls; and 19.7% had superficial ulcerations. Extra-chamber involvement and regional structure invasion occurred in most patients. The frequency of neck node involvement was up to 83.10%; 62.7% of them were bilateral involvement. Patients with T-cell or nature killer/T-cell NHLs had a higher incidence of superficial ulcerations, nasal cavity, and paranasal sinus invasion than B-cell NHLs (P<.05). Patients with B-cell NHLs had a higher incidence of cervical lymphadenopathy specifically in Level VA and parotid region than T-cell or nature killer/T-cell (NK/T-cell) NHLs (P<.05). CONCLUSION:Primary nasopharyngeal NHLs had some characteristic imaging features and different subtypes of nasopharyngeal NHLs had some distinct imaging features.

journal_name

Clin Imaging

journal_title

Clinical imaging

authors

Xie CM,Liu XW,Mo YX,Li H,Geng ZJ,Zheng L,Lv YC,Ban XH,Zhang R

doi

10.1016/j.clinimag.2012.07.009

subject

Has Abstract

pub_date

2013-05-01 00:00:00

pages

458-64

issue

3

eissn

0899-7071

issn

1873-4499

pii

S0899-7071(12)00256-2

journal_volume

37

pub_type

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