Diffusion-weighted magnetic resonance imaging of lung cancer at 3.0 T: a preliminary study on monitoring diffusion changes during chemoradiation therapy.

Abstract:

PURPOSE:The purpose of the study was to prospectively monitor changes of apparent diffusion coefficient (ADC) in perichemoradiation for lung cancer. METHODS:Fourteen patients with lung cancer who underwent chemoradiation therapy were included. Diffusion-weighted (DW) images were obtained prior to and during chemoradiation therapy, and ADCs were compared. RESULTS:Seven patients had qualified DW images before and during chemoradiation. Six responders had significant increase in ADC value during the chemoradiation compared with the pretreatment value (P=.028), while one nonresponder had a slight decrease. CONCLUSION:These preliminary results show the potential of DW imaging in monitoring early response to chemoradiation in patients with lung cancer.

journal_name

Clin Imaging

journal_title

Clinical imaging

authors

Chang Q,Wu N,Ouyang H,Huang Y

doi

10.1016/j.clinimag.2011.07.002

subject

Has Abstract

pub_date

2012-03-01 00:00:00

pages

98-103

issue

2

eissn

0899-7071

issn

1873-4499

pii

S0899-7071(11)00136-7

journal_volume

36

pub_type

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