Abstract:
PURPOSE:The purpose of the study was to prospectively monitor changes of apparent diffusion coefficient (ADC) in perichemoradiation for lung cancer. METHODS:Fourteen patients with lung cancer who underwent chemoradiation therapy were included. Diffusion-weighted (DW) images were obtained prior to and during chemoradiation therapy, and ADCs were compared. RESULTS:Seven patients had qualified DW images before and during chemoradiation. Six responders had significant increase in ADC value during the chemoradiation compared with the pretreatment value (P=.028), while one nonresponder had a slight decrease. CONCLUSION:These preliminary results show the potential of DW imaging in monitoring early response to chemoradiation in patients with lung cancer.
journal_name
Clin Imagingjournal_title
Clinical imagingauthors
Chang Q,Wu N,Ouyang H,Huang Ydoi
10.1016/j.clinimag.2011.07.002subject
Has Abstractpub_date
2012-03-01 00:00:00pages
98-103issue
2eissn
0899-7071issn
1873-4499pii
S0899-7071(11)00136-7journal_volume
36pub_type
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