Prevalence of synchronous second primary malignancy: identification using whole body PET/CT imaging.

Abstract:

OBJECTIVE:To describe the prevalence of synchronous second primary malignancy detected by PET/ CT in our clinical practice and its differentiating features from metastatic lesion. METHODS:All PET/CT scans from 1st October 2009 to 30th September 2010 were reviewed. The suspected cases of synchronous second primary malignancy detected by PET/CT were selected, and the histologically confirmed ones were being illustrated. Metachronous second primary cases were excluded. RESULTS:A total of 1522 scans were reviewed. sixty-eight cases were suspected to have a synchronous second primary while 8 were histologically confirmed. Seven (0.4%) of them were malignant and 1 was a benign tumor. These 7 cases were illustrated, and we found a significant difference in SUV(max) values and site of occurrence unusual to metastasis that were the two main radiological features differentiating them from metastatic lesion. CONCLUSION:Synchronous second primary malignancy could be missed without the use of whole body imaging. Its diagnosis is of utmost importance to prevent erroneous upstaging of disease and subsequent palliative treatment instead of curative surgery.

journal_name

Clin Imaging

journal_title

Clinical imaging

authors

Chun-Sing W,Nan-Jie G,Yiu-Ching C

doi

10.1016/j.clinimag.2013.09.001

subject

Has Abstract

pub_date

2014-03-01 00:00:00

pages

179-86

issue

2

eissn

0899-7071

issn

1873-4499

pii

S0899-7071(13)00229-5

journal_volume

38

pub_type

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