Tetrapeptide H-Ala-Glu-Asp-Arg-OH stimulates expression of cytoskeletal and nuclear matrix proteins.

abstract：:Significant associations between clinical history factors, lipid metabolism parameters, and type of atherosclerotic process (area of vascular lesions and severity of clinical manifestations) were detected. The predominance of generalized atherosclerosis in chronic coronary heart disease group was associated with patie...

journal_title：Bulletin of experimental biology and medicine

authors： Bakarev MA,Karpova AA,Pichigin VI,Nikityuk DB,Lushnikova EL

更新日期：2016-12-01 00:00:00

abstract：:Psychoimmune interactions were studied in women of reproductive age with endometriosis. Pronounced immunological shifts manifested in a shift of the T-cellular immunity, resulting in imbalanced production of pro- (IL-1β, IL-2, IFN-γ) and anti-inflammatory (IL-4) cytokines. Significant correlations between the severity...

journal_title：Bulletin of experimental biology and medicine

authors： Nasyrova RF,Sotnikova LS,Baystrukova NV,Krivoschchekova GV,Novitsky VV,Kupriyanova IE,Semke VY,Naslednikova IO,Baykov AN

更新日期：2011-11-01 00:00:00

abstract：:The development of MPTP-induced depressive syndrome in rats was accompanied by activation of prolyl endopeptidase and dipeptidyl peptidase IV in the brain frontal cortex. Prolyl endopeptidase activity in the striatum also increased under these conditions. Our results indicate that proline-specific peptidases in the ta...

journal_title：Bulletin of experimental biology and medicine

authors： Krupina NA,Zolotov NN,Bogdanova NG,Orlova IN,Khlebnikova NN,Kryzhanovskii GN

更新日期：2006-11-01 00:00:00

abstract：:We proposed a mathematical model and estimated the parameters of adsorption of albumin-bilirubin complex to the surface of carbon pyropolymer. Design data corresponded to the results of experimental studies. Our findings indicate that modeling of this process should take into account fractal properties of the surface ...

journal_title：Bulletin of experimental biology and medicine

authors： Nikolaev AV,Rozhilo YA,Starozhilova TK,Sarnatskaya VV,Yushko LA,Mikhailovskii SV,Kholodov AS,Lobanov AI

更新日期：2005-09-01 00:00:00

abstract：:We studied reflection of artificially induced and amplified food motivation in impulse activity of the masticatory muscles during electrostimulation of "hunger center" of the lateral hypothalamus in the absence and presence of food. The threshold stimulation of the lateral hypothalamus in hungry and satiated animals i...

journal_title：Bulletin of experimental biology and medicine

authors： Ignatova JP,Kromin AA

更新日期：2012-04-01 00:00:00

abstract：:Cytogenetic analysis of karyotypes of hESM01-hESM04 human embryonic stem cells and substrains derived from these strains showed that all these strains retained normal karyotype during long-term culturing. Two substrains of embryonic stem cells with chromosome aberrations indicating clonal origin of these strains were ...

journal_title：Bulletin of experimental biology and medicine

authors： Prokhorovich MA,Lagar'kova MA,Shilov AG,Karamysheva TV,Kiselyov SL,Rubtsov NB

更新日期：2007-07-01 00:00:00

abstract：:Using rat model of experimental sarcoma M-1 we studied the efficacy of photodynamic therapy with boronated chlorine as a photosensitizer in doses of 1.25, 2.5, 5.0, and 10.0 mg/ kg body weight. Laser irradiation was performed at energy densities of 150, 300 J/cm(2) and power density of 0.25 and 0.42 W/cm(2). Treatment...

journal_title：Bulletin of experimental biology and medicine

authors： Kaplan MA,Ol'shevskaya VA,Osipchuk YS,Nikitina RG,Kalinin VN

更新日期：2014-05-01 00:00:00

abstract：:Serum activity of tartrate-resistant acid phosphatase 5b (TRAP 5b) in patients with breast cancer and prostate cancer having bone metastases was much higher than in healthy donors and patients without skeletal injuries. TRAP 5b activity in patients with breast cancer and multiple bone metastases surpassed that in pati...

journal_title：Bulletin of experimental biology and medicine

authors： Lyubimova NV,Pashkov MV,Tyulyandin SA,Gol'dberg VE,Kushlinskii NE

更新日期：2004-07-01 00:00:00

abstract：:The epileptogenic effects of applications of NMDA and kainic acid solutions to the frontal cortex were attenuated in rats receiving ketogenic diet (80% lipids, 3.3% carbohydrates, and 16.7% proteins) during 4 weeks. Spike latency increased, the power of focal epileptic activity decreased, and focus lifetime was shorte...

journal_title：Bulletin of experimental biology and medicine

authors： Kresyun VI,Polyasny VA,Godovan VV,Godlevsky LS

更新日期：2013-02-01 00:00:00

abstract：:We studied changes in cell cycle and apoptosis in normal keratinocytes and melanocytes after exposure to UV-B radiation. UV-B radiation modulated proliferation rate in the studied cell and produced an apoptosis-modulating effect in epidermal melanocytes. ...

journal_title：Bulletin of experimental biology and medicine

authors： Ruksha TG

更新日期：2009-05-01 00:00:00

abstract：:The effects of intranasal administration of oxytocin on the levels and metabolism of monoamines in symmetrical structures of the brain of white outbred mice kept under conditions of long-term social isolation were studied by HPLC. Disappearance of initial right-sided asymmetry in the content of dopamine metabolites in...

journal_title：Bulletin of experimental biology and medicine

authors： Karpova IV,Bychkov ER,Marysheva VV,Mikheev VV,Shabanov PD

更新日期：2017-10-01 00:00:00

abstract：:We studied the mechanisms of combined action of clonidine and local anesthetics amethocaine and imidazo-benzimidazole derivative RU-1117. In contrast to amethocaine, RU-1117 in therapeutic concentrations binds to imidazoline receptors and, to a lesser extent, to alpha(2A)-adrenoceptors on human platelets. Clonidine an...

journal_title：Bulletin of experimental biology and medicine

authors： Ponomarev VP,Galenko-Yaroshevskii AP,Dukhanin AS,Anisimova VA

更新日期：2003-07-01 00:00:00

abstract：:Intraperitoneal injections of hexavalent chromium (sodium bichromate) in the concentrations of 0.025 μg/kg (10-fold lower than MAC; group 1) and 2.5 μg/kg (10-fold higher than MAC; group 2) to rats in a subacute experiment caused dose-dependent morphological changes in the thymus: increased the counts of cells in a st...

journal_title：Bulletin of experimental biology and medicine

authors： Zhumabaeva AN,Zarishnyak NV,Bekmukhambetov EZh

更新日期：2014-02-01 00:00:00

abstract：:We studied multipotent mesenchymal stromal cells isolated from the bone marrow of young (1 month) and old (>12 months) rats. The cell cultures derived from old rats were characterized by lower cell yield in the primary culture, lower number of doublings, and reduced colony-forming capacity of precursor cells. ...

journal_title：Bulletin of experimental biology and medicine

authors： Valyushina MP,Buravkova LB

更新日期：2013-05-01 00:00:00

abstract：:Experiments of 42 outbred male albino rats (160-180 g) showed an increase in the content of CD64, fibroblast growth factor, and proapoptotic proteins (p53 and p21) in the renal cortical matter on day 45 of experimental chronic Masugi nephritis. A positive correlation between CD64 and fibroblast growth factor character...

journal_title：Bulletin of experimental biology and medicine

authors： Rogovyi YE,Arkhipova LG,Dikal MV,Filipova LO,Mil' EN

更新日期：2007-10-01 00:00:00

abstract：:Activation of free radical oxidation and inhibition of antioxidant activity in mouse myocardium after long-term dipyridamole treatment were demonstrated using chemiluminescent techniques. At the same time, dipyridamole 10-fold inhibited free radical oxidation and slightly increased antioxidant activity in the plasma. ...

journal_title：Bulletin of experimental biology and medicine

authors： Ivasenko IN,Shlyakhto EV

更新日期：2001-06-01 00:00:00

abstract：:The peculiarities of the histological structure and morphometrical parameters of the dentition in ISIAH rats (inherited stress-induced arterial hypertension) before stress and after modeling of everyday life stress regimen (chronic stress) were compared with those in WAG rats. The area of blood vessels of the periodon...

journal_title：Bulletin of experimental biology and medicine

authors： Kolesnikova LR,Darenskaya MA,Kolesnikova LI,Grebenkina LA,Korytov LI,Batoroev YK,Belinskaya EI,Mikhalevich IM,Kolesnikov SI

更新日期：2019-05-01 00:00:00

abstract：:Number and size of aggregated lymphoid nodules in the small intestine of mice exposed to radiation using a γ-irradiation unit GOBO-60 with 137Cs source were measured using the methods of visual microscopy and morphometry. Morphological status of the nodules was estimated on days 4, 28, 60, and 90 after the exposure. S...

journal_title：Bulletin of experimental biology and medicine

authors： Klochkova SV,Kvaratskheliya AG,Alekseeva NT,Nikityuk DB

更新日期：2017-12-01 00:00:00

abstract：:We studied the influence of pretreatment with chemical mildronate analogue sibusol on the course of experimental gastric ulcer in rats. Sibusol produced a protective effects on the stomach and duodenum. ...

journal_title：Bulletin of experimental biology and medicine

authors： Lychkova AE,Savchuk VI,Smirnov VM

更新日期：2004-01-01 00:00:00

abstract：:Phosphatidylcholine liposomes in a dose of 25 mg/kg displayed wound-healing properties. They increased the count of alveolar macrophages, lymphocytes, and microvessels in damaged regions and, therefore, attenuated emphysematous changes in the lungs. ...

journal_title：Bulletin of experimental biology and medicine

authors： Kornilova ZK,Selishcheva AA,Perel'man MI

更新日期：2001-02-01 00:00:00

abstract：:The effect of melanin solutions on the skin exposed to UV irradiation (1,050 kJ/m(2)) depended on its dose and varied from photoprotection (0.005 mg/ml) to photosensitization and phototoxicity (burn, 0.1 mg/ml). These results suggest that doses of melanin preparations should be empirically selected to achieve optimum ...

journal_title：Bulletin of experimental biology and medicine

authors： Paramonov BA,Turkovskii II,Potokin IL,Chebotarev VY

更新日期：2002-04-01 00:00:00

abstract：:We studied the effects of dipeptidyl peptidase 4 (DPP4) inhibitor linagliptin on the expression of apoptosis regulator proteins Bcl-2 and Bad in the liver of db/db mice with genetically determined obesity and type 2 diabetes mellitus. The mice received daily linagliptin or saline (placebo) by gavage from week 10 to we...

journal_title：Bulletin of experimental biology and medicine

authors： Michurina SV,Cherepanova MA,Ishchenko IY,Arkhipov SA,Klimontov VV,Zav'yalov EL

更新日期：2019-06-01 00:00:00

abstract：:Maximum magnetic resonance artifacts from stents are often determined by the presence of ferromagnetic compounds in the delivery system. We propose a mathematic model describing artifacts caused by nitinol stents. A method for evaluation of critical radial rigidity of the stents was developed. ...

journal_title：Bulletin of experimental biology and medicine

authors： Sergienko VI,Martynov AK,Petryaikin AV,Koshurnikov DS,Fadeev AA,Nikolaev DA,Karmazanovskii GG,Osipova NY,Fedorov VD

更新日期：2007-09-01 00:00:00

abstract：:The relationships between open field behavior, initial nociceptive thresholds, and immunoreactivity assessed according to the development of hyperthermia triggered by LPS pyrogenal were examined in Wistar rats. Behaviorally active animals demonstrated higher nociceptive thresholds and greater immunoreactivity in compa...

journal_title：Bulletin of experimental biology and medicine

authors： Abramova AY,Abramov YB

更新日期：2011-12-01 00:00:00

abstract：:The effect of non-benzodiazepine anxiolytics on the ethanol-induced hyperlocomotion and behavioral sensitization was assessed in male DBA/2 mice. Selank that enhances activity of the endogenous opioid system (0.3 mg/kg, intraperitoneally), similar to the nonselective opiate receptor blocker naloxone (1.0 mg/kg, intrap...

journal_title：Bulletin of experimental biology and medicine

authors： Kolik LG,Nadorova AV,Seredenin SB

更新日期：2016-11-01 00:00:00

abstract：:We evaluated the concentration dependence and time dependence of the effect of nitroglycerine on intracellular content of cAMP, cGMP, and free Ca2+. It was shown that after norepinephrine stimulation, nitroglycerine exhibited calcium-blocking activity in lower concentrations (starting from 10(-7) M). Under conditions ...

journal_title：Bulletin of experimental biology and medicine

authors： Dukhanin AS,Shimanovskii NL

更新日期：2006-05-01 00:00:00

abstract：:The rate and strength of heart contractions decreased after 10-min perfusion of rat myocardium with Krebs-Henseleit solution containing a selective cannabinoid receptor agonist HU-210 in a final concentration of 10 nM. HU-210 completely blocked the positive inotropic and chronotropic effect of beta-adrenoceptor agonis...

journal_title：Bulletin of experimental biology and medicine

authors： Maslov LN,Lasukova OV,Krylatov AV,Uzhachenko RV,Pertwee R

更新日期：2004-12-01 00:00:00

abstract：:The levels of natural antibodies to β-endorphin, bradykinin, histamine, dopamine, and serotonin were measured in 271 cardiological patients in order to evaluate the severity of their clinical status. The patients were distributed into groups differing by the course of the pathological process. The levels of natural an...

journal_title：Bulletin of experimental biology and medicine

authors： Morozova VS,Petrochenko SN,Myagkova MA,Bachurin SO

更新日期：2017-05-01 00:00:00

abstract：:Solid-phase ELISA revealed increased content of macrophage-granulocyte colony-stimulating factor and basic fibroblast growth factor in the serum of hyperlipoproteinemic patients. ...

journal_title：Bulletin of experimental biology and medicine

authors： Saburova OS,Tvorogova MG,Soboleva EL

更新日期：2003-02-01 00:00:00

abstract：:We studied the effect of moderate heat stress (30oC) and muscarinic cholinergic receptor agonists arecoline and pilocarpine on sensitivity of the behavior of the nematode Caenorhabditis elegans of N2 line to the action of the agonist of nicotinic cholinergic receptor agonist levamisole. Heat stress and muscarinic chol...

journal_title：Bulletin of experimental biology and medicine

authors： Kalinnikova TB,Yakhina AF,Egorova AV,Shagidullin RR,Gainutdinov MH

更新日期：2017-12-01 00:00:00