Single-port donor nephrectomy provides improved patient satisfaction and equivalent outcomes.

Abstract:

OBJECTIVE:Minimally invasive techniques have expanded the donor pool for living kidney donation. We changed our approach to single-port donor nephrectomy in 2009 and have compared outcomes with traditional multiple-port laparoscopic donor nephrectomy. BACKGROUND:The development of minimally invasive surgical techniques to procure kidneys from living donors has allowed expansion of living donor renal transplantation to account for one third of all renal transplants. Recent technical advancement allows for the entire surgical procedure to be done through a single incision contained within the umbilicus. METHODS:We compared outcomes from 135 single-port donor nephrectomies with an immediately preceding cohort of 100 multiple-port laparoscopic donor nephrectomies. Survey data were collected from both groups to compare outcomes. Additional comparisons were made to total center experience with 1300 laparoscopic donor nephrectomies. RESULTS:A total of 135 patients completed successful single-port donor nephrectomy without major complication or open conversion. Another 16 patients required additional port placement because of excessive intra-abdominal fat or limited abdominal domain. Compared with multiple-port donor nephrectomy, single-port patients had similar operative times to cross clamp (2.8 vs 2.6 hours; P = 0.11) that normalized after a learning curve of approximately 50 cases. Recipient creatinine levels were similar at 1 week and 1 month posttransplant. Although 36-Item Short Form Health Surveys demonstrated no significant differences, additional survey data revealed that single-port patients were more satisfied with cosmetic outcomes (P < 0.01) and the overall donation process (P = 0.01). Single-port approach had similar outcomes compared with all previous laparoscopic donor nephrectomies. CONCLUSIONS:Single-port donor nephrectomy can be integrated as a standardized approach for renal donation without additional donor risk, and with benefits of improved patient satisfaction with cosmetic and overall outcomes. Although the primary benefit is cosmetic, (a single incision predominantly contained within the umbilicus) outcomes justify application for kidney donors in experienced centers and may motivate additional living kidney donation.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

Barth RN,Phelan MW,Goldschen L,Munivenkatappa RB,Jacobs SC,Bartlett ST,Philosophe B

doi

10.1097/SLA.0b013e318262ddd6

subject

Has Abstract

pub_date

2013-03-01 00:00:00

pages

527-33

issue

3

eissn

0003-4932

issn

1528-1140

journal_volume

257

pub_type

杂志文章
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    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000658-200008000-00011

    authors: Orozco H,Mercado MA,Chan C,Guillén-Navarro E,López-Martínez LM

    更新日期:2000-08-01 00:00:00

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    doi:10.1097/00000658-199101000-00011

    authors: Hiraide A,Katayama M,Sugimoto H,Yoshioka T,Sugimoto T

    更新日期:1991-01-01 00:00:00

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    abstract:BACKGROUND:Minimal immunosuppression (IS) is desirable in organ transplantation to reduce side effects and to promote the process of tolerance induction. MATERIAL AND METHODS:Between February 2000 and September 2004, 156 adults (>15 years old) receiving a primary liver graft were enrolled in a prospective, randomized,...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/SLA.0b013e31819009c9

    authors: Lerut J,Mathys J,Verbaandert C,Talpe S,Ciccarelli O,Lemaire J,Bonaccorsi-Riani E,Vanthuyne V,Hetsch N,Roggen F,Reyck CD,Goffette P,Latinne D,Orlando G,Rahier J,Sempoux C,Wallemacq P,Laterre PF,Gianello P

    更新日期:2008-12-01 00:00:00

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    journal_title:Annals of surgery

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    doi:10.1097/00000658-197804000-00011

    authors: Washburn ME,Balk MW,Mazat BA,Zurlo JA

    更新日期:1978-04-01 00:00:00

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    doi:10.1097/SLA.0000000000001622

    authors: Bolckmans R,Himpens J

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    doi:10.1097/00000658-197702000-00005

    authors: O'Donnell TF Jr

    更新日期:1977-02-01 00:00:00

  • A systematic review of economic evaluations of enhanced recovery pathways for colorectal surgery.

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    journal_title:Annals of surgery

    pub_type: 杂志文章,评审

    doi:10.1097/SLA.0b013e318295fef8

    authors: Lee L,Li C,Landry T,Latimer E,Carli F,Fried GM,Feldman LS

    更新日期:2014-04-01 00:00:00

  • Reperfusion inhibits elevated splanchnic prostanoid production after hemorrhagic shock.

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    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199012000-00006

    authors: Myers SI,Taylor BJ,Stanislawska M

    更新日期:1990-12-01 00:00:00

  • Colon cancer cells that are not growth inhibited by TGF-beta lack functional type I and type II TGF-beta receptors.

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    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199506000-00015

    authors: MacKay SL,Yaswen LR,Tarnuzzer RW,Moldawer LL,Bland KI,Copeland EM 3rd,Schultz GS

    更新日期:1995-06-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e31818584c7

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    journal_title:Annals of surgery

    pub_type: 杂志文章

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    authors: Tukiainen E,Kallio M,Lepäntalo M

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    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

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    更新日期:2017-10-01 00:00:00

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    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000658-197906000-00004

    authors: Stone HH,Haney BB,Kolb LD,Geheber CE,Hooper CA

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    pub_type: 杂志文章

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    authors: Simien C,Holt KD,Richter TH,Whalen TV,Coburn M,Havlik RJ,Miller RS

    更新日期:2010-08-01 00:00:00

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    pub_type: 杂志文章,随机对照试验

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    doi:10.1097/00000658-197606000-00003

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    更新日期:1976-06-01 00:00:00

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    pub_type: 杂志文章

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    pub_type: 杂志文章

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    journal_title:Annals of surgery

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    pub_type: 杂志文章,多中心研究

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    更新日期:1998-02-01 00:00:00