The role of immunosuppression in the efficacy of cancer gene therapy using adenovirus transfer of the herpes simplex thymidine kinase gene.

abstract：:Thrombotic complications of heparin administration were observed in eight patients during a two year period. At sites of subcutaneous heparin injection, six patients developed areas of the skin and subcutaneous necrosis. Systemic thrombotic events and thrombocytopenia were observed in two of these patients when they r...

journal_title：Annals of surgery

authors： White PW,Sadd JR,Nensel RE

更新日期：1979-11-01 00:00:00

abstract：OBJECTIVES:To develop, validate, and implement a competency assessment tool (CAT) for technical surgical performance in the context of a summative assessment process for the National Training Programme in Laparoscopic Colorectal Surgery (NTP). BACKGROUND:The NTP is an educational initiative by the National Cancer Acti...

journal_title：Annals of surgery

authors： Miskovic D,Ni M,Wyles SM,Kennedy RH,Francis NK,Parvaiz A,Cunningham C,Rockall TA,Gudgeon AM,Coleman MG,Hanna GB,National Training Programme in Laparoscopic Colorectal Surgery in England.

更新日期：2013-03-01 00:00:00

abstract：:Spectral analysis was used to examine 257 carotid arteries in 227 patients who had undergone carotid endarterectomy at 1, 3, 6, and 12 months after surgery and annually thereafter. Routine intraoperative completion angiography ensured that the operations were technically satisfactory. Postoperative restenoses were ide...

journal_title：Annals of surgery

authors： Thomas M,Otis SM,Rush M,Zyroff J,Dilley RB,Bernstein EF

更新日期：1984-07-01 00:00:00

abstract：OBJECTIVE:Comparative effectiveness research has mostly been focused on comparison of treatment techniques. The goal of the present study was to extend the research to physician specialty. BACKGROUND:Both surgeons and interventionalists (cardiologists and radiologists) are involved in endovascular repairs (EVAR) of ao...

journal_title：Annals of surgery

authors： McCutcheon BA,Talamini MA,Chang DC,Rose JA,Bandyk DF,Wilson SE

更新日期：2013-09-01 00:00:00

abstract：:Six patients with surgically treated Menetrier's disease are presented. Diffuse or focal cystic hyperplasia of mucous secreting epithelium of the fundus with antral sparing characterized the stomachs in all of these cases. In most instances the disorder was found during evaluation of non-specific complaints of pain, n...

journal_title：Annals of surgery

authors： Davis JM,Gray GF,Thorbjarnarson B

更新日期：1977-04-01 00:00:00

abstract：OBJECTIVE:Pancreatic mucinous cystic neoplasms (MCNs) provide a spectrum of neoplastic changes ranging from benign to malignant. The authors have correlated K-ras mutations and p53 overexpression with the evolution of these tumors. METHODS:Areas of mild, moderate, or severe dysplasia were microdissected from paraffin-...

journal_title：Annals of surgery

authors： Jimenez RE,Warshaw AL,Z'graggen K,Hartwig W,Taylor DZ,Compton CC,Fernández-del Castillo C

更新日期：1999-10-01 00:00:00

abstract：:The morphologic characteristics of a scar may render it an "immunologically privileged site" providing fertile ground for tumor occurrence and growth. We sought to extend this concept and to determine the effect of different stages of wound healing on tumor occurrence. Syngeneic strain-2 guinea pigs and a methylcholan...

journal_title：Annals of surgery

authors： Pendergrast WJ Jr,Futrell JW

更新日期：1979-02-01 00:00:00

abstract：OBJECTIVE:Patients with major burns and an animal model of burn injury were studied to determine the mechanism of depressed interleukin-2 (IL-2) production after thermal injury and to determine the effect of such injury on IL-2 receptor (IL-2R) expression and function. SUMMARY BACKGROUND DATA:Major burn injury is know...

journal_title：Annals of surgery

authors： Horgan AF,Mendez MV,O'Riordain DS,Holzheimer RG,Mannick JA,Rodrick ML

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:To determine the accuracy of fine-needle aspiration (FNA) and vacuum-assisted core biopsy (VACB) in assessing the presence of residual cancer in the breast after neoadjuvant systemic therapy (NST). SUMMARY BACKGROUND DATA:Pathologic complete response (pCR) rates after NST have improved dramatically, suggesti...

journal_title：Annals of surgery

authors： Kuerer HM,Rauch GM,Krishnamurthy S,Adrada BE,Caudle AS,DeSnyder SM,Black DM,Santiago L,Hobbs BP,Lucci A Jr,Gilcrease M,Hwang RF,Candelaria RP,Chavez-MacGregor M,Smith BD,Arribas E,Moseley T,Teshome M,Miggins MV,Vale

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVES:Because neural invasion (NI) is still inconsistently reported and not well characterized within gastrointestinal malignancies (GIMs), our aim was to determine the exact prevalence and severity of NI and to elucidate the true impact of NI on patient's prognosis. BACKGROUND:The union internationale contre le ...

journal_title：Annals of surgery

authors： Liebl F,Demir IE,Mayer K,Schuster T,DʼHaese JG,Becker K,Langer R,Bergmann F,Wang K,Rosenberg R,Novotny AR,Feith M,Reim D,Friess H,Ceyhan GO

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:The authors assess the effect of surgical margin width on recurrence rates after intestinal resection of Crohn's Disease (CD). BACKGROUND:The optimal width of margins when resecting DC of the small bowel is controversial. Most studies have been retrospective and have had conflicting results. METHODS:Patient...

journal_title：Annals of surgery

authors： Fazio VW,Marchetti F,Church M,Goldblum JR,Lavery C,Hull TL,Milsom JW,Strong SA,Oakley JR,Secic M

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:This study provided an objective survey by an outside auditing group of a large, complete patient population undergoing laparoscopic cholecystectomies, determined the frequency of complications, especially bile duct injuries, and presented a system for classifying and comparing the severity of bile duct injur...

journal_title：Annals of surgery

authors： Wherry DC,Rob CG,Marohn MR,Rich NM

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:Regional circulatory changes in intestinal mucosa were evaluated after the onset of septic shock and the effect of nitric oxide (NO) inhibition on mucosal blood flow was investigated at different locations along the intestine. SUMMARY BACKGROUND DATA:The response of intestinal blood flow to different physiol...

journal_title：Annals of surgery

authors： Klemm K,Moody FG

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:To document the decreased incidence of surgical complications after pancreas transplantation in recent times. SUMMARY BACKGROUND DATA:Compared with other abdominal transplants, pancreas transplants have historically had the highest incidence of surgical complications. However, over the past few years, the au...

journal_title：Annals of surgery

authors： Humar A,Kandaswamy R,Granger D,Gruessner RW,Gruessner AC,Sutherland DE

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:To review retrospectively a 4-year experience with pediatric surgical networking at a major academic medical center in the Midwest. BACKGROUND:The growth of managed care in the United States during the past decade has had a major impact on the practice of medicine in general, but especially on academic medic...

journal_title：Annals of surgery

authors： Coran AG,Blackman PM,Sikina C,Harmon CM,Lelli JL Jr,Geiger JD,Hirschl RB,Teitelbaum DH,Polley TZ Jr,Golladay ES,Austin E,Adelman SH

更新日期：1999-09-01 00:00:00

abstract：:In our series of 101 patients with small bowel bypass for morbid obesity, nine developed biliary calculi postoperatively during a mean follow-up of 29.6 months. The development of gallstones depends in part on biliary cholesterol saturation and on the zeta potential of bile. In eight consecutive patients, the lithogen...

journal_title：Annals of surgery

authors： Wise L,Stein T

更新日期：1978-01-01 00:00:00

abstract：OBJECTIVE:To assess the distant metastatic potential of duodeno-pancreatic neuroendocrine tumors (DP-NETs) in patients with MEN1, according to functional status and size. SUMMARY BACKGROUND DATA:DP-NETs, with their numerous lesions and endocrine secretion-related symptoms, continue to be a medical challenge; unfortuna...

journal_title：Annals of surgery

authors： Vinault S,Mariet AS,Le Bras M,Mirallié E,Cardot-Bauters C,Pattou F,Ruszniewski P,Sauvanet A,Chanson P,Baudin E,Elias D,Menegaux F,Gaujoux S,Borson-Chazot F,Lifante JC,Caron P,Carrère N,Tabarin A,Laurent C,Klein M,

更新日期：2020-12-01 00:00:00

abstract：:Seventy-five consecutive patients who sustained injuries to the duodenum were admitted to our hospital over a nine-year period. Nineteen blunt injuries and 56 penetrating injuries were encountered. Blunt injuries were usually the result of motor vehicle accidents and steering wheel impact was frequently implicated. Pe...

journal_title：Annals of surgery

authors： Flint LM Jr,McCoy M,Richardson JD,Polk HC Jr

更新日期：1980-06-01 00:00:00

abstract：OBJECTIVE:To assess the authors' hypothesis that with modern techniques, the current risks of repair for both complete and partial atrioventricular canal (AVC) are equal. SUMMARY BACKGROUND DATA:Repair of complete AVC in infancy has traditionally carried a substantial mortality. In contrast, partial AVC has been consi...

journal_title：Annals of surgery

authors： Cope JT,Fraser GD,Kouretas PC,Kron IL

更新日期：2002-10-01 00:00:00

abstract：:During the past 20 months, 28 patients with symptomatic gastroesophageal reflux were treated with the Angelchik anti-reflux prosthesis. The patients ranged in age from 12 to 75 years, with symptoms present from one to 24 years. Vigorous medical management had failed with all patients prior to surgery. Before operation...

journal_title：Annals of surgery

authors： Starling JR,Reichelderfer MO,Pellett JR,Belzer FO

更新日期：1982-06-01 00:00:00

abstract：:The effect of reperfusion following hemorrhagic shock on splanchnic prostanoid release was studied. Anesthetized male rats were bled to a mean arterial blood pressure of 30 mmHg for 30 minutes and either killed or treated with shed blood for 60 minutes and then killed. The superior mesenteric arterial bed was cannulat...

journal_title：Annals of surgery

authors： Myers SI,Taylor BJ,Stanislawska M

更新日期：1990-12-01 00:00:00

abstract：:The clinical outcome in 155 patients with papillary or follicular carcinoma of the thyroid gland operated on over a 25-year period demonstrated no difference in survival rates or incidence of recurrent tumor between those treated by total thyroidectomy and those undergoing less than total thyroidectomy. However, the c...

journal_title：Annals of surgery

authors： Farrar WB,Cooperman M,James AG

更新日期：1980-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of inhalation of aerosolized opsonized dead Escherichia coli on inflammatory pulmonary neutrophil (PMN) apoptosis, lung injury, and survival in a PMN-mediated lung injury model in vivo. SUMMARY BACKGROUND DATA:Neutrophils that have transmigrated into an inflammatory focus display incre...

journal_title：Annals of surgery

authors： Sookhai S,Wang JJ,McCourt M,Kirwan W,Bouchier-Hayes D,Redmond P

更新日期：2002-02-01 00:00:00

abstract：:This report describes 140 cases in which Linton splenorenal shunts were performed for the management of the complications of portal hypertension by a large number of surgeons in a single hospital. There was a history of variceal bleeding in 130. Using the Childs designation to reflect hepatic functional reserve, the o...

journal_title：Annals of surgery

authors： Ottinger LW

更新日期：1982-12-01 00:00:00

abstract：OBJECTIVE:To investigate the incidence of nodal metastasis in a consecutive series of patients treated at the authors' institution with highly selective criteria, and to determine the impact that lymphatic mapping and sentinel node biopsy have on the detection of nodal metastases in this carefully selected patient popu...

journal_title：Annals of surgery

authors： Jakub JW,Ebert MD,Diaz NM,Cantor A,Reintgen DS,Dupont EL,Shons AR,Cox CE

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVES:To develop a risk prediction model for serious complications after bariatric surgery. BACKGROUND:Despite evidence for improved safety with bariatric surgery, serious complications remain a concern for patients, providers and payers. There is little population-level data on which risk factors can be used to ...

journal_title：Annals of surgery

authors： Finks JF,Kole KL,Yenumula PR,English WJ,Krause KR,Carlin AM,Genaw JA,Banerjee M,Birkmeyer JD,Birkmeyer NJ,Michigan Bariatric Surgery Collaborative, from the Center for Healthcare Outcomes and Policy.

更新日期：2011-10-01 00:00:00

abstract：:Forty-nine patients with chronic ulcerative colitis refractory to medical therapy and four with multiple polyposis have undergone total colectomy, mucosal protectomy, and endorectal ileal pull-through with ileoanal anastomosis at the UCLA Medical Center during the past 12 years (mean age, 19.4 years). Thirty-eight pat...

journal_title：Annals of surgery

authors： Fonkalsrud EW

更新日期：1984-02-01 00:00:00

abstract：OBJECTIVE:To assess whether regional intestinal oxygen saturation (rintSO2) and regional cerebral oxygen saturation (rcSO2) measurements aid in estimating survival of preterm infants after surgery for NEC. SUMMARY OF BACKGROUND DATA:Predicting survival after surgery for NEC is difficult yet of the utmost importance fo...

journal_title：Annals of surgery

authors： Kuik SJ,van der Heide M,Bruggink JLM,Bos AF,Verhagen AAE,Kooi EMW,Hulscher JBF

更新日期：2020-04-20 00:00:00

abstract：:A prospective, manometric trial of anal fissure treated by subcutaneous lateral internal sphincterotomy (SLIS) was designed to elucidate the pathophysiology of this condition. Anorectal manometry with a closed, precalibrated, water-filled microballoon using the station pull-through technique was performed on 13 patien...

journal_title：Annals of surgery

authors： McNamara MJ,Percy JP,Fielding IR

更新日期：1990-02-01 00:00:00

abstract：OBJECTIVE:To determine the incidence of Wnt pathway activation in patients with stage I NSCLC and its influence on lung cancer recurrence. BACKGROUND:Despite resection, the 5-year recurrence with localized stage I nonsmall cell lung cancer (NSCLC) is 18.4%-24%. Aberrant Wnt signaling activation plays an important role...

journal_title：Annals of surgery

authors： Shapiro M,Akiri G,Chin C,Wisnivesky JP,Beasley MB,Weiser TS,Swanson SJ,Aaronson SA

更新日期：2013-03-01 00:00:00