A comparative study of the elective treatment of variceal hemorrhage with beta-blockers, transendoscopic sclerotherapy, and surgery: a prospective, controlled, and randomized trial during 10 years.

Abstract:

OBJECTIVE:To compare three options for the elective treatment of portal hypertension during a 10-year period. METHODS:Patients included in the trial were 18 to 76 years old, had a history of bleeding portal hypertension, and had undergone no prior treatment. Treatment options were beta-blockers (propranolol), sclerotherapy, and portal blood flow-preserving procedures (selective shunts and the Sugiura-Futagawa operation). RESULTS:A total of 119 patients were included: 40 in the pharmacology group, 46 in the sclerotherapy group,and 33 in the surgical group. The three groups showed no differences in terms of age, Child-Pugh classification, and cause of liver disease. The rebleeding rate was significantly lower in the surgical group than in the other two groups. The rebleeding rate was only 5% in the Child A surgical group, compared with 71% and 68% for the sclerotherapy and pharmacotherapy groups, respectively. Survival was better for the low-risk patients (Child A) in the three groups, but when the three options were compared, no significant difference was found. CONCLUSIONS:Portal blood flow-preserving procedures offer the lowest rebleeding rate in low-risk patients undergoing elective surgery.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

Orozco H,Mercado MA,Chan C,Guillén-Navarro E,López-Martínez LM

doi

10.1097/00000658-200008000-00011

subject

Has Abstract

pub_date

2000-08-01 00:00:00

pages

216-9

issue

2

eissn

0003-4932

issn

1528-1140

journal_volume

232

pub_type

临床试验,杂志文章,随机对照试验
  • A prospective, randomized, controlled trial of preoperative transarterial chemoembolization for resectable large hepatocellular carcinoma.

    abstract:OBJECTIVE:To evaluate the effect of preoperative transarterial chemoembolization (TACE) for resectable large hepatocellular carcinoma (HCC). SUMMARY BACKGROUND DATA:Resection of HCC is potentially curative, but local recurrence is very common. There is currently no effective neoadjuvant or adjuvant therapy. METHODS:F...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/SLA.0b013e3181961c16

    authors: Zhou WP,Lai EC,Li AJ,Fu SY,Zhou JP,Pan ZY,Lau WY,Wu MC

    更新日期:2009-02-01 00:00:00

  • Colorectal carcinoma in patients under age 40.

    abstract::Patients under the age of 40 with colorectal cancer (29 females, 18 males) were compared with similar patients in our general hospital population and analyzed for patterns of presentation, stage at diagnosis, degree of tumor differentiation, and survival. There was a higher incidence of poorly differentiated tumors in...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198511000-00013

    authors: Behbehani A,Sakwa M,Ehrlichman R,Maguire P,Friedman S,Steele GD Jr,Wilson RE

    更新日期:1985-11-01 00:00:00

  • Gallstone pancreatitis: biliary tract pathology in relation to time of operation.

    abstract::During a 29-month trial, 65 patients with acute gallstone pancreatitis were randomly selected for biliary tract explorations either within 73 hours of admission (36 patients) or at three months following remission with nonoperative measures (29 patients, with five others awaiting elective operation). The details of su...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198109000-00008

    authors: Stone HH,Fabian TC,Dunlop WE

    更新日期:1981-09-01 00:00:00

  • Perfect Registration Leads to Imperfect Performance: A Randomized Trial of Multimodal Intraoperative Image Guidance.

    abstract:OBJECTIVE:To compare surgical safety and efficiency of 2 image guidance modalities, perfect augmented reality (AR) and side-by-side unregistered image guidance (IG), against a no guidance control (NG), when performing a simulated laparoscopic cholecystectomy (LC). BACKGROUND:Image guidance using AR offers the potentia...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/SLA.0000000000002793

    authors: Dilley JWR,Hughes-Hallett A,Pratt PJ,Pucher PH,Camara M,Darzi AW,Mayer EK

    更新日期:2019-02-01 00:00:00

  • Overestimation of hereditary breast cancer risk.

    abstract:OBJECTIVE:To find out how women with breast or ovarian cancer rate their chances of carrying hereditary factors for these cancers and to determine the extent to which they overestimate their risk. SUMMARY BACKGROUND DATA:BRCA1 and BRCA2 are genes that cause breast and ovarian cancer when they are inherited in families...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199809000-00010

    authors: Iglehart JD,Miron A,Rimer BK,Winer EP,Berry D,Shildkraut MJ

    更新日期:1998-09-01 00:00:00

  • Increased cardiac endocrine activity after common bile duct ligation in the rabbit. Atrial endocrine cells in obstructive jaundice.

    abstract:OBJECTIVE:This study investigated the pathogenesis of water and sodium metabolism derangements in obstructive jaundice. SUMMARY BACKGROUND DATA:Obstructive jaundice is associated with hypodipsia, depletion of extracellular water, alterations of the water and sodium regulating hormones, and an increased incidence of re...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199401000-00012

    authors: Pereira JA,Torregrosa MA,Martínez-Ródenas F,Clària J,Pallarés L,Gubern JM,Ruano-Gil D,Sitges-Serra A

    更新日期:1994-01-01 00:00:00

  • Aortoenteric fistula. Incidence, presentation recognition, and management.

    abstract::Twenty-two patients developed one or more aortoenteric fistulae following aortic reconstruction with a dacron graft. Endoscopy was performed on 11 of these patients on 17 occasions and a preoperative diagnosis was made in eight patients. Fistulous communication was most common between the aorta and duodenum (60%), and...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198203000-00011

    authors: Champion MC,Sullivan SN,Coles JC,Goldbach M,Watson WC

    更新日期:1982-03-01 00:00:00

  • The 100 Most Cited Papers in the History of the American Surgical Association.

    abstract:OBJECTIVE:The aim of this study was to determine characteristics of the most cited publications in the history of the American Surgical Association (ASA). SUMMARY BACKGROUND DATA:The Annals of Surgery has served as the journal of record for the ASA since 1928, with a special issue each year dedicated to papers present...

    journal_title:Annals of surgery

    pub_type: 历史文章,杂志文章

    doi:10.1097/SLA.0000000000003633

    authors: Landreneau JP,Weaver M,Delaney CP,Aminian A,Dimick JB,Lillemoe KD,Schauer PR

    更新日期:2020-04-01 00:00:00

  • Cytology of peritoneal lavage performed during staging laparoscopy for gastrointestinal malignancies: is it useful?

    abstract:OBJECTIVE:To evaluate the potential benefit of cytology of the peritoneal lavage obtained during diagnostic laparoscopy for staging gastrointestinal (GI) malignancies. SUMMARY BACKGROUND DATA:Peritoneal lavage is a simple procedure that can be performed during laparotomy for GI tumors. Tumor cells in the lavage fluid ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199812000-00002

    authors: Nieveen van Dijkum EJ,Sturm PD,de Wit LT,Offerhaus J,Obertop H,Gouma DJ

    更新日期:1998-12-01 00:00:00

  • Clinical characteristics and current management of medically refractory unstable angina.

    abstract::Of 531 patients admitted to the Duke Coronary Care Unit with unstable angina (UA) from June 1981 to September 1982, 100 had persistent angina despite optimal medical therapy of nitrates, propranolol, and nifedipine. At catheterization, 70% of the refractory patients had left main (LM) or three-vessel disease (TVD), 68...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198410000-00007

    authors: Rankin JS,Newton JR Jr,Califf RM,Jones RH,Wechsler AS,Oldham HN Jr,Wolfe WG,Lowe JE

    更新日期:1984-10-01 00:00:00

  • Delayed presentation of traumatic diaphragmatic hernia.

    abstract::Twenty-five patients with traumatic diaphragmatic hernia discovered at least five months after injury are described, of whom 18 were male and seven female. All but one hernia occurred on the left side. Stab wounds were the etiological factor in 22 patients and blunt trauma in three. The diagnosis was most often made b...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197808000-00016

    authors: Hegarty MM,Bryer JV,Angorn IB,Baker LW

    更新日期:1978-08-01 00:00:00

  • Hyperparathyroidism in the elderly.

    abstract::Primary hyperparathyroidism was studied in a well-defined geriatric population of 1129 individuals during a three-month interval. Primary hyperparathyroidism was diagnosed in 1.5%. The diagnosis was based on a morphologic and biochemic basis. From clinical material consisting of 400 patients treated surgically for pri...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198302000-00003

    authors: Tibblin S,Pålsson N,Rydberg J

    更新日期:1983-02-01 00:00:00

  • Retained and recurrent bile duct stones. Surgical or nonsurgical removal?

    abstract::An experience with 69 patients who underwent 72 common bile duct reoperations for retained or recurrent choledocholithiasis is presented. The mean age of the patients was 57 years, and 35 patients had associated conditions. In this series six patients (8.3%) had minor complications and no patient developed major compl...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198102000-00004

    authors: Girard RM,Legros G

    更新日期:1981-02-01 00:00:00

  • Strategies in the surgical treatment of malignant ventricular arrhythmias. An 8-year experience.

    abstract::Introduction of the automatic implantable cardioverter defibrillator (AICD) has dramatically affected the surgical treatment of malignant ventricular tachyarrhythmias. The authors continue to perform electrophysiologically directed subendocardial resection (SER) of left ventricular (LV) scars in selected patients, and...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199209000-00010

    authors: Geha AS,Elefteriades JA,Hsu J,Biblo LA,Hoch DH,Batsford WP,Rosenfeld LE,Carlson MD,Johnson NJ,Waldo AL

    更新日期:1992-09-01 00:00:00

  • Accelerated perinecrotic outgrowth of colorectal liver metastases following radiofrequency ablation is a hypoxia-driven phenomenon.

    abstract:OBJECTIVE:The aim of this study was to assess how thermal ablation of colorectal liver metastases affects the outgrowth of micrometastases in the transition zone (TZ) between ablated tissue and the unaffected reference zone (RZ) in 2 different murine models. BACKGROUND:Thermal destruction therapies of nonresectable co...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3181a38ef5

    authors: Nijkamp MW,van der Bilt JD,de Bruijn MT,Molenaar IQ,Voest EE,van Diest PJ,Kranenburg O,Borel Rinkes IH

    更新日期:2009-05-01 00:00:00

  • The anatomy of the fasciae of the face and neck with particular reference to the spread and treatment of intraoral infections (Ludwig's) that have progressed into adjacent fascial spaces.

    abstract::Descriptions of the fasciae of the lower half of the face and of the adjacent cervical fasciae have long been puzzling and descriptively much too complex. For this reason, medical students, young medical and dental practitioners, and at times even senior surgeons frequently do not understand the anatomy of the cervico...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198612000-00015

    authors: Lindner HH

    更新日期:1986-12-01 00:00:00

  • Parasympathetic innervation and pancreatic secretion: the role of the gastric antrum.

    abstract::The role of the antrum on vagally mediated pancreatic secretion was studied in 8 conscious dogs prepared with chronic pancreatic and gastric fistulae. After completion of control studies 6 were subjected to antrectomy and 2 to antroneurolysis (to interrupt submucosal nerve connections); secretory studies were repeated...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197603000-00005

    authors: Rosenberg IR,Zambrano VJ,Janowitz HD,Rudick J

    更新日期:1976-03-01 00:00:00

  • Laparoscopic versus open appendectomy: a prospective randomized double-blind study.

    abstract:SUMMARY BACKGROUND DATA:The value of laparoscopy in appendicitis is not established. Studies suffer from multiple limitations. Our aim is to compare the safety and benefits of laparoscopic versus open appendectomy in a prospective randomized double blind study. METHODS:Two hundred forty-seven patients were analyzed fo...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/01.sla.0000179648.75373.2f

    authors: Katkhouda N,Mason RJ,Towfigh S,Gevorgyan A,Essani R

    更新日期:2005-09-01 00:00:00

  • The effect of sacral nerve modulation on cerebral evoked potential latency in fecal incontinence and constipation.

    abstract:OBJECTIVE:Influence of sacral nerve modulation (SNM) on cerebral somatosensory evoked potentials (SEP) was determined in patients with incontinence and constipation. BACKGROUND:Selection of patients with incontinence and constipation for SNM could be improved. METHODS:The latency (ms) of SEP induced by pudendal nerve...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3182196ff4

    authors: Giani I,Novelli E,Martina S,Clerico G,Luc AR,Trompetto M,Malaguti S,Nicholls J,Ganio E

    更新日期:2011-07-01 00:00:00

  • Significance of Examined Lymph Node Number in Accurate Staging and Long-term Survival in Resected Stage I-II Pancreatic Cancer-More is Better? A Large International Population-based Cohort Study.

    abstract:OBJECTIVE:This large international cohort study aimed to investigate the associations of examined lymph node (ELN) number with accurate staging and long-term survival in pancreatic adenocarcinoma (PaC) and to robustly determine the minimal and optimal ELN thresholds. SUMMARY BACKGROUND DATA:ELN number is an important ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000003558

    authors: Huang L,Jansen L,Balavarca Y,van der Geest L,Lemmens V,Groot Koerkamp B,van Santvoort HC,Grützmann R,Besselink MG,Schrotz-King P,Brenner H

    更新日期:2019-08-13 00:00:00

  • Intra-aortic balloon counterpulsation: potential for therapy in hemorrhagic shock with associated myocardial failure.

    abstract::After attaching appropriate monitoring devices enabling the measurement of the slope of the left ventricular function curve, left atrial pressure, mean aortic pressure, peak left ventricular pressure, and tension time index, three groups of ten dogs were subjected to varying periods of hemorrhagic shock until a slope ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197501000-00025

    authors: Proctor HJ,Hsiao H,Fry J,Ebert C

    更新日期:1975-01-01 00:00:00

  • Indications for different modes of surgical therapy in medically refractory ventricular arrhythmias.

    abstract::Fifty-one adult patients were referred for surgical treatment during the time period from July 1980 to November 1985. The average age was 59 +/- 6 years (19-70 years). All patients had symptomatic ventricular tachycardia that was refractory to standard or experimental drug therapy. On the basis of patient condition, s...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198606000-00013

    authors: Hammon JW Jr,Echt DS,Merrill WH,Primm KR,Woosley RL,Smith RF,Roden DM,Bender HW Jr

    更新日期:1986-06-01 00:00:00

  • Modified technique of obturator bypass in failed or infected grafts.

    abstract::The obturator bypass graft operation can be performed in a moderately simplified manner by a technique that allows extension of indications for the procedure beyond situations in which sepsis is present in the groin. Long-term analysis of the results of the cases available for study indicates that the procedure may ve...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198303000-00015

    authors: Pearce WH,Ricco JB,Yao JS,Flinn WR,Bergan JJ

    更新日期:1983-03-01 00:00:00

  • Chemical debridement of burns.

    abstract::The development of effective, non-toxic (local and systemic) methods for the rapid chemical (enzymatic and non-enzymatic) debridement of third degree burns would dramatically reduce the morbidity and mortality of severely burned patients. Sepsis is still the major cause of death of patients with extensive deep burns. ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197410000-00032

    authors: Levenson SM,Kan D,Gruber C,Crowley LV,Lent R,Watford A,Seifter E

    更新日期:1974-10-01 00:00:00

  • Impact of a clinical pathway for elective infrarenal aortic reconstructions.

    abstract:OBJECTIVE:To determine the impact of a clinical pathway for elective infrarenal aortic reconstruction on outcome, resource utilization, and cost in a university medical center. SUMMARY BACKGROUND DATA:Clinical pathways have been reported to control costs, reduce resource utilization, and maintain or improve the qualit...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199805000-00009

    authors: Huber TS,Carlton LM,Harward TR,Russin MM,Phillips PT,Nalli BJ,Flynn TC,Seeger JM

    更新日期:1998-05-01 00:00:00

  • Outcomes of Posterior Component Separation With Transversus Abdominis Muscle Release and Synthetic Mesh Sublay Reinforcement.

    abstract:OBJECTIVE:To evaluate the safety and efficacy of transversus abdominis muscle release (TAR) with retrorectus synthetic mesh reinforcement in a large series of complex hernia patients. BACKGROUND:Posterior component separation via TAR during abdominal wall reconstruction (AWR) continues to gain popularity. Although our...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000001673

    authors: Novitsky YW,Fayezizadeh M,Majumder A,Neupane R,Elliott HL,Orenstein SB

    更新日期:2016-08-01 00:00:00

  • Occlusion of the pancreatic duct versus pancreaticojejunostomy: a prospective randomized trial.

    abstract:OBJECTIVE:Using a prospective randomized study to assess postoperative morbidity and pancreatic function after pancreaticoduodenectomy with pancreaticojejunostomy and duct occlusion without pancreaticojejunostomy. SUMMARY BACKGROUND DATA:Postoperative complications after pancreaticoduodenectomy are largely due to leak...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000658-200210000-00004

    authors: Tran K,Van Eijck C,Di Carlo V,Hop WC,Zerbi A,Balzano G,Jeekel H

    更新日期:2002-10-01 00:00:00

  • The American Medical Association's Section on Surgery: The Beginnings of the Organization, Professionalization, and Specialization of Surgery in the United States.

    abstract:OBJECTIVE:To explore the founding of the American Medical Association's Section on Surgery in 1859 and how it represented, on a national basis, the beginnings of organized surgery and the formal start of the professionalization and specialization of surgery in the United States. BACKGROUND:The broad social process of ...

    journal_title:Annals of surgery

    pub_type: 传,历史文章,杂志文章

    doi:10.1097/SLA.0000000000001635

    authors: Rutkow I

    更新日期:2017-01-01 00:00:00

  • The Effect of Arterial Disease Level on Outcomes of Supervised Exercise Therapy for Intermittent Claudication: A Prospective Cohort Study.

    abstract:OBJECTIVE:To assess whether level of arterial obstruction determines the effectiveness of SET in patients with IC. BACKGROUND DATA:Guidelines advocate SET before invasive treatment for IC, but early revascularization remains widespread, especially in patients with aortoiliac disease. METHODS:Patients were recruited f...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000004073

    authors: van den Houten MML,Jansen S,van der Laan L,Vriens PWHE,Willigendael EM,Koelemay MJW,Scheltinga MRM,Teijink JAW,ELECT Study Group.

    更新日期:2020-07-24 00:00:00

  • Antibiotic prophylaxis in acute nonperforated appendicitis. The Danish Multicenter Study Group III.

    abstract::In a prospective, block-randomized, multicenter study, the safety and efficacy of cefoxitin in preoperative prophylaxis were studied. 1735 patients undergoing appendectomy were evaluable, and half of these patients received 2 g of cefoxitin before undergoing operation. The patients were divided into three groups: pati...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/00000658-198903000-00010

    authors: Bauer T,Vennits B,Holm B,Hahn-Pedersen J,Lysen D,Galatius H,Kristensen ES,Graversen P,Wilhelmsen F,Skjoldborg H

    更新日期:1989-03-01 00:00:00