当前位置： SCI文献检索 > JOURNAL OF INORGANIC BIOCHEMISTRY期刊下所有文献 > Structural comparison of the poplar plastocyanin isoforms PCa and PCb sheds new light on the role of the copper site geometry in interactions with redox partners in oxygenic photosynthesis.

Structural comparison of the poplar plastocyanin isoforms PCa and PCb sheds new light on the role of the copper site geometry in interactions with redox partners in oxygenic photosynthesis.

Abstract：

:Plastocyanin (PC) from poplar leaves is present in two isoforms, PCa and PCb, which differ in sequence by amino acid replacements at locations remote from the copper center and simultaneously act in the photosynthetic electron-transport chain. We describe ultra-high resolution structures of PCa and high-resolution structures of PCb, both under oxidizing and reducing conditions at pH 4, 6 and 8. The docking on cytochrome f and photosystem I, respectively, has been modeled for both isoforms. PCa and PCb exhibit closely similar overall and active-site structures, except for a difference in the relative orientation of the acidic patches. The isoforms exhibit substantial differences in the dependence of the reduced (Cu(I)) geometry on pH. In PCa, the decrease in pH causes a gradual dissociation of His87 from Cu(I) at low pH, probably adopting a neutral tautomeric state. In PCb, the histidine remains covalently bound to Cu(I) and may adopt a doubly protonated state at low pH. The fact that both isoforms have similar although not identical functions in photosynthetic electron flows suggests that the His87 imidazole does not play a crucial role for the pathway of electron transport from cytochrome f to oxidized PC.

journal_name

J Inorg Biochem

journal_title

Journal of inorganic biochemistry

authors

Kachalova GS,Shosheva AC,Bourenkov GP,Donchev AA,Dimitrov MI,Bartunik HD

doi

10.1016/j.jinorgbio.2012.07.015

subject

Has Abstract

pub_date

2012-10-01 00:00:00

pages

174-81

eissn

0162-0134

issn

1873-3344

pii

S0162-0134(12)00233-4

journal_volume

115

pub_type

杂志文章

相关文献

JOURNAL OF INORGANIC BIOCHEMISTRY文献大全
  • Effect of inositol hexakisphosphate on the spectroscopic properties of the nitric oxide derivative of ferrous naturally glycated human hemoglobin HbA1c.

    abstract：:The effect of inositol hexakisphosphate (IHP) on the spectroscopic (EPR and absorbance) properties of the nitric oxide derivative of ferrous naturally glycated human hemoglobin HbA1c (HbA1cNO) has been investigated quantitatively. The results obtained show that 1) both in the absence and presence of IHP, the EPR and a...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(88)85014-1

    authors： Ascenzi P,Desideri A,Amiconi G,Bertollini A,Bolognesi M,Castagnola M,Coletta M,Brunori M

    更新日期：1988-09-01 00:00:00

  • Interactions of trialkyllead compounds with rat liver mitochondria.

    abstract：:The interactions of two trialkyllead (TAL) compounds, (trimethyl)Pb-Cl and (tributyl)Pb-Cl, with mitochodria from rat liver have been studied. A stimulation of the respiratory rate induced by the trialkyllead compounds added at low doses was observed which was not dependent on the presence of chloride in the medium. I...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0162-0134(97)10036-8

    authors： Bragadin M,Marton D,Murgia M,Rizzoli V,Scutari G,Deana R

    更新日期：1998-03-01 00:00:00

  • Stability constants of copper(II) mixed complexes with some 4-quinolone antibiotics and (N-N) donors.

    abstract：:Studies of complexation equilibria of the antibiotic anions nalidixate and cinoxacinate with [Cu(phen)]2+ and [Cu(bipy)]2+ are reported. These studies indicate that the stability of this type of complex is strongly related to the metal environment. A correlation between the stability constants, determined here, with t...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(96)00041-4

    authors： Mendoza-Díaz G,Perez-Alonso R,Moreno-Esparza R

    更新日期：1996-11-15 00:00:00

  • Exploring anticancer efficiency of mitochondria-targeted cyclometalated iridium(III) complexes.

    abstract：:We prepared and characterized new iridium(III) complexes: [Ir(NC)2(MPPIP)](PF6) (N-C = 2-phenylpyridine 1; benzo[h]quinolone 2; 1-phenylisoquinolone, 3, MPPIP = 2-(4-(4'-methylpiperazin-yl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline). MTT (MTT = 3-(4,5-dimethylthiazole-2-yl)-2,5-biphenyl tetrazolium bromide) method ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2020.111215

    authors： Gu Y,Wen H,Bai L,Zhou Y,Zhang H,Tian L,Zhang Y,Hao J,Liu Y

    更新日期：2020-11-01 00:00:00

  • Cisplatin-mediated selective hydrolytic cleavage of methionine-containing peptides with neighboring serine or histidine residues.

    abstract：:The pH- and time-dependent reactions of the anticancer drug cisplatin, cis-[PtCl(2)(NH(3))(2)], with the peptides Ac-Gly-Met-Gly-OH, Ac-Ser-Met-OH and Ac-Met-His-OH (Gly=glycyl, Met=methionyl, Ser=seryl, His=histidyl) at 313 K have been investigated by high-performance liquid chromatography, nuclear magnetic resonance...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2004.08.016

    authors： Manka S,Becker F,Hohage O,Sheldrick WS

    更新日期：2004-11-01 00:00:00

  • Iron core formation in horse spleen ferritin: magnetic susceptibility, pH, and compositional studies.

    abstract：:Horse spleen ferritin (HoSF) reconstituted with small iron cores ranging in size from 8 to 500 iron atoms was studied by magnetic susceptibility and pH measurements to determine when the added Fe3+ begins to aggregate and form antiferromagnetically coupled clusters and also to determine the hydrolytic state of the iro...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(94)85004-6

    authors： Hilty S,Webb B,Frankel RB,Watt GD

    更新日期：1994-11-15 00:00:00

  • Biotinylated platinum(IV) complexes designed to target cancer cells.

    abstract：:Three biotinylated platinum(IV) complexes (1-3) were designed and synthesized. The resulting platinum(IV) complexes exhibited effective cytotoxicity against the tested cancer cell lines, especially complex 1, which was 2.0-9.6-fold more potent than cisplatin. These complexes were found to be rapidly reduced to their a...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2017.08.017

    authors： Zhao J,Hua W,Xu G,Gou S

    更新日期：2017-11-01 00:00:00

  • Nanosized flower-like ZnO synthesized by a simple hydrothermal method and applied as matrix for horseradish peroxidase immobilization for electro-biosensing.

    abstract：:Nanosized flower-like ZnO was synthesized by a simple hydrothermal method which is a convenient, environment friendly, inexpensive and efficient process. Raman spectroscopy, X-ray diffraction (XRD) and scanning electron microscope (SEM) were used to confirm the material structure and the crystallite microstructure. Th...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2005.07.001

    authors： Liu YL,Yang YH,Yang HF,Liu ZM,Shen GL,Yu RQ

    更新日期：2005-10-01 00:00:00

  • Application of tris(2,2'-bipyridyl)ruthenium(III) for the investigation of DNA spatial structure by a chemical modification method.

    abstract：:It was shown that the treatment of a DNA fragment and a hepta-decanucleotide having a hairpin structure by Ru(2,2'-bipyridyl)3(3+) complex at 15 degrees C in 1 M NaCl for 10-60 min, and subsequent hydrolysis in 1 M piperidine at 95 degrees C led to the specific cleavage of the polynucleotide chain at guanosine residue...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(88)85025-6

    authors： Fedorova OS,Podust LM

    更新日期：1988-11-01 00:00:00

  • Coordination and redox properties of copper interaction with α-synuclein.

    abstract：:Parkinson's disease (PD) is a severe neurodegenerative disorder affecting movements. After Alzheimer's disease, it is the most common form of neurodegeneration. PD is characterized by the loss of neurons producing dopamine and by the presence of protein aggregates in the brain, known as Lewy bodies. The main constitue...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章,评审

    doi：10.1016/j.jinorgbio.2016.04.012

    authors： Valensin D,Dell'Acqua S,Kozlowski H,Casella L

    更新日期：2016-10-01 00:00:00

  • Conserved cysteine residues are necessary for nickel-induced allosteric regulation of the metalloregulatory protein YqjI (NfeR) in E. coli.

    abstract：:Transition metal homeostasis is necessary to sustain life. First row transition metals act as cofactors within the cell, performing vital functions ranging from DNA repair to respiration. However, intracellular metal concentrations exceeding physiological requirements may be toxic. In E. coli, the YqjH flavoprotein is...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.04.016

    authors： Blahut M,Dzul S,Wang S,Kandegedara A,Grossoehme NE,Stemmler T,Outten FW

    更新日期：2018-07-01 00:00:00

  • DNA binding, oxidative DNA cleavage, cytotoxicity, and apoptosis-inducing activity of copper(II) complexes with 1,4-tpbd (N,N,N',N'-tetrakis(2-yridylmethyl)benzene-1,4-diamine) ligand.

    abstract：:Three new binuclear copper(II) complexes have been synthesized and structurally characterized by X-ray crystallography, [Cu(2)(1,4-tpbd)(dafo)(2)(MeOH)(2)](ClO(4))(4)·2.5H(2)O (1), [Cu(2)(1,4-tpbd) (DMSO)(2)(ClO(4))(2)](OH)(2)·6H(2)O (2) and [Cu(2)(1,4-tpbd)(OAC)(2)(ClO(4))(2)]·5H(2)O (3) (1,4-tpbd=N,N,N',N'-tetrakis(...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2011.03.012

    authors： Li DD,Tian JL,Gu W,Liu X,Zeng HH,Yan SP

    更新日期：2011-06-01 00:00:00

  • Study on structure-property-reactivity-function relationship of human neuronal growth inhibitory factor (hGIF).

    abstract：:Human metallothionein-3 (hMT3), also named as human neuronal growth inhibitory factor (hGIF), can inhibit the outgrowth of embryonic cortical neurons in the presence of brain extracts. In order to systematically study the structure-property-reactivity-function relationship of hGIF, our laboratory designed a series of ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章,评审

    doi：10.1016/j.jinorgbio.2008.07.007

    authors： Ding ZC,Zheng Q,Cai B,Ni FY,Yu WH,Teng XC,Gao Y,Liu F,Chen D,Wang Y,Wu HM,Sun HZ,Zhang MJ,Tan XS,Huang ZX

    更新日期：2008-11-01 00:00:00

  • Influence of the introduction of a triphenylphosphine group on the anticancer activity of a copper complex.

    abstract：:Aiming at obtaining new copper complexes with good cytotoxicity against cancer cells, triphenylphosphine (TPP) was introduced to obtain insight into the influence of the co-ligands. In this paper, two copper complexes, Cu(2-pbmq)(CH3OH)Br2 (1) and [Cu(2-pbmq)(TPP)Br]2 (2) were designed, synthesized, and characterized ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2020.111102

    authors： Li S,Zhao J,Guo Y,Mei Y,Yuan B,Gan N,Zhang J,Hu J,Hou H

    更新日期：2020-09-01 00:00:00

  • The adrenodoxin-like ferredoxin of Schizosaccharomyces pombe mitochondria.

    abstract：:The single mitochondrial type I [2Fe-2S] ferredoxin of the fission yeast Schizosaccharomyces pombe is produced as the carboxy terminal part of the electron-transfer-protein 1 (etp1) and cleaved off during mitochondrial import [Biochemistry 41 (2002) 2311-2321]. The UV/Vis (UV-visible) spectrum of the purified recombin...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2004.02.006

    authors： Schiffler B,Bureik M,Reinle W,Müller EC,Hannemann F,Bernhardt R

    更新日期：2004-07-01 00:00:00

  • Triplet of cysteines - Coordinational riddle?

    abstract：:Polythiol binding of metal ions plays crucial role in the proper functioning of cysteine-rich proteins that are responsible for metal homeostasis and defending processes against metal toxicity (including heavy metals detoxification). The coordination properties of cysteine residues involved in specific sequencional pa...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2019.110957

    authors： Krzywoszyńska K,Swiątek-Kozłowska J,Potocki S,Ostrowska M,Kozłowski H

    更新日期：2020-03-01 00:00:00

  • Reduction of oxaporphyrin ring of CO-bound α-verdoheme complexed with heme oxygenase-1 by NADPH-cytochrome P450 reductase.

    abstract：:Heme oxygenase (HO) catalyses the degradation of heme to biliverdin, carbon monoxide (CO) and ferrous iron via three successive monooxygenase reactions, using electrons provided by NADPH-cytochrome P450 reductase (CPR) and oxygen molecules. For cleavage of the oxaporphyrin ring of ferrous α-verdoheme, an intermediate ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2010.11.010

    authors： Sato H,Higashimoto Y,Sakamoto H,Sugishima M,Shimokawa C,Harada J,Palmer G,Noguchi M

    更新日期：2011-02-01 00:00:00

  • Copper(I) interaction with model peptides of WD6 and TM6 domains of Wilson ATPase: regulatory and mechanistic implications.

    abstract：:With the aim to investigate the mechanism of Cu(I) transport by Wilson ATPase (ATP7B), we have studied the interaction of the peptides 2K10p (CH(3)CO-Lys-Gly-Met-Thr-Cys-Ala-Ser-Cys-Val-His-Asn-Lys-CONH(2)), and 2K8p (CH(3)CO-Lys-Leu-Cys-Ile-Ala-Cys-Pro-Cys-Ser-Lys-CONH(2)), part of the sixth metal binding domain (WD6...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2004.05.013

    authors： Myari A,Hadjiliadis N,Fatemi N,Sarkar B

    更新日期：2004-09-01 00:00:00

  • The effect of pyrophosphate, tripolyphosphate and ATP on the rate of the Fenton reaction.

    abstract：:It has been recently reported that pyrophosphate, tri-polyphosphate, ATP and analogous ligands considerably decrease the yield of hydroxyl radicals by the Fenton reaction under conditions where [H(2)O(2)]>[Fe(II)L(n)]. It was suggested that this effect is due to the slowing down of the Fenton reaction by these ligands...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2011.01.009

    authors： Rachmilovich-Calis S,Masarwa A,Meyerstein N,Meyerstein D

    更新日期：2011-05-01 00:00:00

  • Substrate preference of the HIF-prolyl hydroxylase-2 (PHD2) and substrate-induced conformational change.

    abstract：:HIF prolyl-4-hydroxylase 2 (PHD2) is a non-heme Fe, 2-oxoglutarate (2OG) dependent dioxygenase that regulates the hypoxia inducible transcription factor (HIF) by hydroxylating two conserved prolyl residues in N-terminal oxygen degradation domain (NODD) and C-terminal oxygen degradation domain (CODD) of HIF-1α. Prior s...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2013.05.006

    authors： Pektas S,Knapp MJ

    更新日期：2013-09-01 00:00:00

  • Covalent heme attachment to the protein in human heme oxygenase-1 with selenocysteine replacing the His25 proximal iron ligand.

    abstract：:To characterize heme oxygenase with a selenocysteine (SeCys) as the proximal iron ligand, we have expressed truncated human heme oxygenase-1 (hHO-1) His25Cys, in which Cys-25 is the only cysteine, in the Escherichia coli cysteine auxotroph strain BL21(DE3)cys. Selenocysteine incorporation into the protein was demonstr...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2008.11.002

    authors： Jiang Y,Trnka MJ,Medzihradszky KF,Ouellet H,Wang Y,Ortiz de Montellano PR

    更新日期：2009-03-01 00:00:00

  • Synthesis, properties, and antitumor effects of a new mixed phosphine gold(I) compound in human colon cancer cells.

    abstract：:The antineoplastic potential of a new stable mixed phosphine gold(I) complex containing tris(tert-butyl)phosphine (tBu3P) and bis(diphenylphosphino)ethene (dppet), namely [Au(tBu3P)(dppet)Cl], has been investigated in the human colon cancer HCT-116 cell line. The (31)P NMR solution study, confirms the structural featu...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2013.03.014

    authors： Lupidi G,Avenali L,Bramucci M,Quassinti L,Pettinari R,Khalife HK,Gali-Muhtasib H,Marchetti F,Pettinari C

    更新日期：2013-07-01 00:00:00

  • Vanadyl(IV) binding to mammalian ferritins. An EPR study aided by site-directed mutagenesis.

    abstract：:During its metabolism, vanadium is known to become associated with the iron storage protein, ferritin. To elucidate probable vanadium binding sites on the protein, VO2+ binding to mammalian ferritins was studied using site-directed mutagenesis and EPR spectroscopy. VO2+-apoferritin EPR spectra of human H-chain (100% H...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0162-0134(00)00046-5

    authors： Grady JK,Shao J,Arosio P,Santambrogio P,Chasteen ND

    更新日期：2000-05-30 00:00:00

  • Cytotoxicity and DNA interaction in a series of aryl terminated iminopyridine Pt(II) complexes.

    abstract：:A series of iminopyridine complexes of platinum(II), bearing a flexible diethereal, aryl terminated residue, where the size of aryl group is varied from phenyl to 9-anthracenyl, was synthesized. The new complexes are soluble and stable in DMSO/H2O mixtures. Besides the metal center, aryl groups are available for furth...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2020.111335

    authors： Bondi R,Dalla Via L,Hyeraci M,Pagot G,Labella L,Marchetti F,Samaritani S

    更新日期：2020-12-15 00:00:00

  • A molecular cytogenetic approach to studying platinum resistance.

    abstract：:The technique of comparative genomic hybridisation (CGH) has until recently been used to screen for common genomic abnormalities in fresh tumour material; it has identified previously unrecognised regions of amplification associated with poor prognosis subtypes of breast cancer and lymphoma. Our group has applied this...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0162-0134(99)00140-3

    authors： Hiorns LR,Seckl MJ,Paradinas F,Sharp SY,Skelton LA,Brunstrom G,Newlands ES,Kelland LR,Leyland-Jones B

    更新日期：1999-10-01 00:00:00

  • The axial ligand and extent of protein folding determine whether Zn or Cu binds to amicyanin.

    abstract：:M98Q amicyanin is isolated with zinc bound to its type 1 copper-binding site. The influence of the axial ligand of the type 1 copper site on metal specificity is strongest prior to the completion of protein folding and adoption of the final type 1 site geometry. The preference for zinc over copper correlated with the ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2007.09.007

    authors： Ma JK,Lee S,Choi M,Bishop GR,Hosler JP,Davidson VL

    更新日期：2008-02-01 00:00:00

  • The copper-enzyme dopamine beta-monooxygenase: studies on the ability of several metals to inhibit the enzyme activity and to replace the copper.

    abstract：:The ability of several metals to inhibit dopamine beta-monooxygenase was measured and compared with their ability to compete with the binding of 64Cu to the water-soluble form of the bovine adrenal enzyme at pH 6.0. In the presence of an optimal concentration of copper (0.5 microM in the present assay system), an inhi...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(84)80006-9

    authors： Skotland T,Flatmark T

    更新日期：1984-01-01 00:00:00

  • Synthesis, crystal structure and nuclease activity of a Schiff base copper(II) complex.

    abstract：:A new Schiff base copper(II) complex, Cu(o-VANAHE)(2) (o-VANAHE = 2-(o-vanillinamino)-1-hydroxyethane), has been synthesized and characterized. Single crystal X-ray diffraction results suggest that this complex structure belongs to triclinic crystal system, space group P1 with the following crystallographic parameters...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2005.01.017

    authors： Li LZ,Zhao C,Xu T,Ji HW,Yu YH,Guo GQ,Chao H

    更新日期：2005-05-01 00:00:00

  • Covalent attachment of the heme to Synechococcus hemoglobin alters its reactivity toward nitric oxide.

    abstract：:The cyanobacterium Synechococcus sp. PCC 7002 produces a monomeric hemoglobin (GlbN) implicated in the detoxification of reactive nitrogen and oxygen species. GlbN contains a b heme, which can be modified under certain reducing conditions. The modified protein (GlbN-A) has one heme-histidine C-N linkage similar to the...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2017.09.018

    authors： Preimesberger MR,Johnson EA,Nye DB,Lecomte JTJ

    更新日期：2017-12-01 00:00:00

  • Structure-activity relationships in a series of auranofin analogues showing remarkable antiproliferative properties.

    abstract：:The antiproliferative properties of a series of structurally-related gold(I) and silver(I) linear complexes inspired to the clinically established gold-based drug auranofin were investigated in A2780 ovarian cancer cells and in their auranofin (A2780/AF-R) and cisplatin (A2780/CDDP-R) resistant counterparts. In A2780 ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2020.111079

    authors： Landini I,Massai L,Cirri D,Gamberi T,Paoli P,Messori L,Mini E,Nobili S

    更新日期：2020-07-01 00:00:00