Detection, scoring and volume assessment of bone erosions by ultrasonography in rheumatoid arthritis: comparison with CT.

Abstract:

OBJECTIVES:To determine the accuracy of ultrasonography (US) for bone erosion detection in different areas of rheumatoid arthritis (RA) metacarpophalangeal (MCP) joints with multislice CT as the reference method. Second, to establish the necessary bone volume loss on CT for US to reliably detect it as an erosion, and finally to compare two semiquantitative US-erosion scoring methods. METHODS:The 2nd-5th MCP joints of 49 patients with RA were examined by CT and US, and evaluated for the presence of bone erosion in each MCP joint quadrant. On CT, erosion volume was scored according to the OMERACT-RAMRIS score (bone volume loss in 10% increments of original bone volume). US erosions were scored 0-3 according to the Szkudlarek and Scoring by UltraSound Structural erosion (ScUSSe) systems, respectively. RESULTS:Seven hundred and eighty-four MCP joint quadrants were examined. Erosions were detected by CT in 259 quadrants and by US in 142 quadrants. Sensitivity/specificity/accuracy of US was overall 44%/95%/78% compared with 71%/95%/90% in areas with good US accessibility (radial 2nd MCP, ulnar 5th MCP and all dorsal/palmar aspects). US detected 95% of erosions with bone volume loss >20%. In US accessible areas, 63% of erosions with 1-10% bone volume loss and 94% of erosions with >10% bone loss were detected. The two US scoring systems agreed well on large erosions, whereas the smallest erosions (Szkudlarek grade 1, of which 86% were confirmed by CT) were not scored by ScUSSe. CONCLUSION:In accessible areas, US was highly accurate for detection and semiquantitative assessment of RA bone erosion. Even the smallest erosions, only detected in one plane, were generally confirmed by CT.

journal_name

Ann Rheum Dis

authors

Døhn UM,Terslev L,Szkudlarek M,Hansen MS,Hetland ML,Hansen A,Madsen OR,Hasselquist M,Møller J,Ostergaard M

doi

10.1136/annrheumdis-2011-201114

subject

Has Abstract

pub_date

2013-04-01 00:00:00

pages

530-4

issue

4

eissn

0003-4967

issn

1468-2060

pii

annrheumdis-2011-201114

journal_volume

72

pub_type

临床试验,杂志文章
  • Autoantibodies to type II collagen: occurrence in rheumatoid arthritis, other arthritides, autoimmune connective tissue diseases, and chronic inflammatory syndromes.

    abstract::Serum IgG antibodies to native and denatured human type II collagen (Col II) were measured using an enzyme linked immunosorbent assay (ELISA). One hundred and thirty one patients with various forms of arthritis such as rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis (PSA). Reiter's Syndrome...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.47.4.313

    authors: Choi EK,Gatenby PA,McGill NW,Bateman JF,Cole WG,York JR

    更新日期:1988-04-01 00:00:00

  • Serum IgG antibodies to peptidylarginine deiminase 4 in rheumatoid arthritis and associations with disease severity.

    abstract:BACKGROUND:Antibodies targeting citrullinated antigens are specific for rheumatoid arthritis (RA). Citrullination is catalysed by the peptidylarginine deiminase (PAD) enzyme family. Critical enzymes are often targeted by disease-specific antibodies in complex immune-mediated diseases. Here, we have tested for autoantib...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.2007.080267

    authors: Halvorsen EH,Pollmann S,Gilboe IM,van der Heijde D,Landewé R,Ødegård S,Kvien TK,Molberg Ø

    更新日期:2008-03-01 00:00:00

  • Efficacy and safety of peficitinib (ASP015K) in patients with rheumatoid arthritis and an inadequate response to conventional DMARDs: a randomised, double-blind, placebo-controlled phase III trial (RAJ3).

    abstract:OBJECTIVES:To investigate the efficacy and safety of peficitinib, an oral Janus kinase inhibitor, in patients with rheumatoid arthritis (RA). METHODS:In this double-blind phase III study, patients with RA and an inadequate response to prior disease-modifying anti-rheumatic drugs (DMARDs) were randomised to peficitinib...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章,随机对照试验

    doi:10.1136/annrheumdis-2019-215163

    authors: Tanaka Y,Takeuchi T,Tanaka S,Kawakami A,Iwasaki M,Song YW,Chen YH,Wei JC,Lee SH,Rokuda M,Izutsu H,Ushijima S,Kaneko Y,Akazawa R,Shiomi T,Yamada E

    更新日期:2019-10-01 00:00:00

  • Neuropsychiatric syndromes in patients with systemic lupus erythematosus and primary Sjögren syndrome: a comparative population-based study.

    abstract:OBJECTIVES:To compare the prevalence and pattern of neuropsychiatric (NP) syndromes observed in systemic lupus erythematosus (SLE) to patients with Primary Sjögren syndrome (PSS) using the American College of Rheumatology (ACR) criteria for the 19 NP syndromes seen in SLE. METHODS:A population-based study was conducte...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.2008.098301

    authors: Harboe E,Tjensvoll AB,Maroni S,Gøransson LG,Greve OJ,Beyer MK,Herigstad A,Kvaløy JT,Omdal R

    更新日期:2009-10-01 00:00:00

  • Rituximab combined with Peg-interferon-ribavirin in refractory hepatitis C virus-associated cryoglobulinaemia vasculitis.

    abstract:OBJECTIVES:To report the results of a pilot study using rituximab combined with Peg-interferon (IFN) alpha2b-ribavirin in severe refractory hepatitis C virus (HCV) related mixed cryoglobulinaemia (MC) vasculitis. METHODS:Sixteen consecutive patients with severe HCV-MC vasculitis that were resistant (n = 11) or relapse...

    journal_title:Annals of the rheumatic diseases

    pub_type: 临床试验,杂志文章

    doi:10.1136/ard.2007.081653

    authors: Saadoun D,Resche-Rigon M,Sene D,Perard L,Karras A,Cacoub P

    更新日期:2008-10-01 00:00:00

  • Late onset spondylarthropathy: clinical and biological comparison with early onset patients.

    abstract:OBJECTIVE:To compare the clinical, radiological, and biological profile of patients presenting late onset spondylarthropathy (LOSPA) with patients with early onset spondylarthropathy (EOSPA). METHODS:During the period April 1987 to April 1995 a retrospective chart review of inpatients and outpatients identified eight ...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.56.3.176

    authors: Caplanne D,Tubach F,Le Parc JM

    更新日期:1997-03-01 00:00:00

  • Anti-intermediate filament antibodies, antikeratin antibody, and antiperinuclear factor in rheumatoid arthritis and infectious mononucleosis.

    abstract::Sera from patients with rheumatoid arthritis (RA), patients with infectious mononucleosis (IM), and blood donors were tested by indirect immunofluorescence for the presence of antikeratin antibody (AKA), antibody to cytoskeletal intermediate filaments of prekeratin or vimentin type (AIFA) and antiperinuclear factor (A...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.44.7.446

    authors: Kataaha PK,Mortazavi-Milani SM,Russell G,Holborow EJ

    更新日期:1985-07-01 00:00:00

  • Cigarette smoking and the risk for cartilage loss and knee pain in men with knee osteoarthritis.

    abstract:OBJECTIVE:To examine the effects of smoking on cartilage loss and pain at the knee in individuals with knee osteoarthritis. METHODS:159 men with symptomatic knee osteoarthritis who participated in a 30-month, prospective, natural history study of knee osteoarthritis were examined. The more symptomatic knee was imaged ...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.2006.056697

    authors: Amin S,Niu J,Guermazi A,Grigoryan M,Hunter DJ,Clancy M,LaValley MP,Genant HK,Felson DT

    更新日期:2007-01-01 00:00:00

  • Rheumatoid factor measured by fluoroimmunoassay: a responsive measure of rheumatoid arthritis disease activity that is associated with joint damage.

    abstract:OBJECTIVES:To determine whether rheumatoid factors (RFs), measured as continuous variables by time resolved fluoroimmunoassay, reflect disease activity in rheumatoid arthritis (RA). Further, to study the association of RFs and other disease activity parameters with radiological joint damage, especially in individual pa...

    journal_title:Annals of the rheumatic diseases

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1136/ard.61.7.603

    authors: Knijff-Dutmer E,Drossaers-Bakker W,Verhoeven A,van der Sluijs Veer G,Boers M,van der Linden S,van de Laar M

    更新日期:2002-07-01 00:00:00

  • D-penicillamine and immune complex deposition.

    abstract::Dense, granular immunoglobulin deposits have been identified at the epidermo-dermal junction in 4 out of 10 patients who developed toxic reactions to D-penicillamine therapy for rheumatoid arthritis. Three of 4 patients developing a lupus-like syndrome while on penicillamine had similar findings on skin biopsy. Serum ...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.38.4.344

    authors: Kirby JD,Dieppe PA,Huskisson EC,Smith B

    更新日期:1979-08-01 00:00:00

  • Normal intestinal microbiota in the aetiopathogenesis of rheumatoid arthritis.

    abstract::A series of observations have led to the hypothesis that normal intestinal microbiota in patients with rheumatoid arthritis may harbour, for genetic reasons, bacteria with cell walls capable of inducing arthritis. Differences occur between bacterial species, and even between strains of a single species, because some c...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1136/ard.62.9.807

    authors: Toivanen P

    更新日期:2003-09-01 00:00:00

  • Standardisation of synovial tissue infiltrate analysis: how far have we come? How much further do we need to go?

    abstract::Changes in cellular infiltrate and expression of cytokines, chemokines, and cell adhesion molecules as a result of therapeutic interventions in rheumatoid arthritis can be demonstrated in the synovial membrane. However, before synovial tissue analysis can be used as an outcome measure in such studies, standardisation ...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1136/ard.2005.036905

    authors: Smith MD,Baeten D,Ulfgren AK,McInnes IB,Fitzgerald O,Bresnihan B,Tak PP,Veale D,OMERACT synovial special interests group.

    更新日期:2006-01-01 00:00:00

  • A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus.

    abstract:OBJECTIVE:To investigate whether the risk allele for systemic lupus erythematosus (SLE) in the signal transducer and activator of transcription factor 4 (STAT4) gene, defined by the single nucleotide polymorphism (SNP) rs10181656(G), is associated with vascular events and/or presence of prothrombotic anti-phospholipid ...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1136/ard.2009.115535

    authors: Svenungsson E,Gustafsson J,Leonard D,Sandling J,Gunnarsson I,Nordmark G,Jönsen A,Bengtsson AA,Sturfelt G,Rantapää-Dahlqvist S,Elvin K,Sundin U,Garnier S,Simard JF,Sigurdsson S,Padyukov L,Syvänen AC,Rönnblom L

    更新日期:2010-05-01 00:00:00

  • Geode development and multiple fractures in rheumatoid arthritis.

    abstract::The radiological development from normal bone of geodes and subsequent fractures in phalanges of two adjacent fingers is described in a patient with classical rheumatoid arthritis. Presentation was as a septic, discharging focus, but infection was excluded; the pathology is described. ...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.44.2.130

    authors: Lowthian PJ,Calin A

    更新日期:1985-02-01 00:00:00

  • Clinical and ultrasonographic predictors of joint replacement for knee osteoarthritis: results from a large, 3-year, prospective EULAR study.

    abstract:OBJECTIVES:To determine clinical and ultrasonographic predictors of joint replacement surgery across Europe in primary osteoarthritis (OA) of the knee. METHODS:This was a 3-year prospective study of a painful OA knee cohort (from a EULAR-sponsored, multicentre study). All subjects had clinical evaluation, radiographs ...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1136/ard.2008.099564

    authors: Conaghan PG,D'Agostino MA,Le Bars M,Baron G,Schmidely N,Wakefield R,Ravaud P,Grassi W,Martin-Mola E,So A,Backhaus M,Malaise M,Emery P,Dougados M

    更新日期:2010-04-01 00:00:00

  • Influence of HLA polymorphism on persistent remission in rheumatoid arthritis.

    abstract:BACKGROUND:Several studies have reported an association between the presence of the shared epitope (SE) and susceptibility to rheumatoid arthritis (RA). Recent studies have shown that certain HLA-DRB1 alleles in combination with predisposing DQB1 and DQA1 alleles may protect against the development of RA. This model is...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.61.4.351

    authors: Molenaar ET,Voskuyl AE,van der Horst-Bruinsma IE,Schreuder GM,Zanelli E,Dijkmans BA

    更新日期:2002-04-01 00:00:00

  • Hydroxychloroquine and lupus pregnancy: review of a series of 36 cases.

    abstract:OBJECTIVE:To study maternal and fetal outcome of pregnancy in patients with lupus who were exposed to hydroxychloroquine (HCQ). METHODS:The case records of women (n = 33) exposed to HCQ during their pregnancies (n = 36) and of 53 control patients from a single lupus pregnancy centre were reviewed to determine lupus ac...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.55.7.486

    authors: Buchanan NM,Toubi E,Khamashta MA,Lima F,Kerslake S,Hughes GR

    更新日期:1996-07-01 00:00:00

  • Antibodies to histones in systemic lupus erythematosus: prevalence, specificity, and relationship to clinical and laboratory features.

    abstract::Antibodies to histones (AHA) are commonly found in patients with systemic lupus erythematosus (SLE). However, the full profile of AHA and their clinical associations remains unclear. A total of 111 patients with SLE were studied, including 13 patients in whom multiple serum samples were available over several years. I...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.51.1.61

    authors: Cohen MG,Pollard KM,Webb J

    更新日期:1992-01-01 00:00:00

  • Indomethacin serum concentrations in man. Effects of dosage, food, and antacid.

    abstract::In the use of anti-inflammatory compounds, sustained serum levels are thought to be related to drug efficacy. This study shows that frequent clinical administration of indomethacin can result in sustained serum levels of the drug and that food and antacid may have important modifying effects on serum indomethacin conc...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.35.4.333

    authors: Emori HW,Paulus H,Bluestone R,Champion GD,Pearson C

    更新日期:1976-08-01 00:00:00

  • Isolation and analysis of immune complexes from sera of patients with polymyalgia rheumatica and giant cell arteritis.

    abstract::Serum samples were obtained from patients with polymyalgia rheumatica (PMR: n = 10) or giant cell arteritis (GCA; n = 7), or both. Samples were taken either before treatment or within one week of starting prednisolone. Immune complexes (IC) were concentrated by polyethylene glycol (PEG) precipitation then purified wit...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.46.6.468

    authors: Smith AJ,Kyle V,Cawston TE,Hazleman BL

    更新日期:1987-06-01 00:00:00

  • How long should we talk to patients? A study in doctor-patient communication.

    abstract::The 13 questions to which 173 rheumatic outpatients most frequently wished to know the answer were made the basis of a structured interview. Two lengths of interview were conducted in a controlled trial (short being of 2 minutes' duration, long ranging from 4 to 11 minutes). Sixty patients referred directly from their...

    journal_title:Annals of the rheumatic diseases

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/ard.41.3.250

    authors: Wright V,Hopkins R,Burton K

    更新日期:1982-06-01 00:00:00

  • Calcinosis of joints and periarticular tissues associated with vitamin D intoxication.

    abstract::We describe a patient with rheumatoid arthritis and widespread joint and periarticular calcinosis related to self-medication with vitamin D, which was aggravated by oral phosphate therapy prescribed for her hypercalcaemia. Hydroxyapatite was shown in the synovial fluid from affected joints. The role played by tissue i...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.44.7.494

    authors: Butler RC,Dieppe PA,Keat AC

    更新日期:1985-07-01 00:00:00

  • The incidences of and consultation rate for lower extremity complaints in general practice.

    abstract:OBJECTIVE:To estimate the incidence and consultation rate of lower extremity complaints in general practice. METHODS:Data were obtained from the Second Dutch National Survey of General Practice, in which 195 general practitioners (GPs) in 104 practices recorded all contacts with patients during 12 consecutive months i...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.2005.036988

    authors: van der Waal JM,Bot SD,Terwee CB,van der Windt DA,Schellevis FG,Bouter LM,Dekker J

    更新日期:2006-06-01 00:00:00

  • Major improvements in health-related quality of life during the use of etanercept in patients with previously refractory juvenile idiopathic arthritis.

    abstract:OBJECTIVE:To evaluate changes in health-related quality of life (HRQoL) in patients with refractory juvenile idiopathic arthritis (JIA) who are being treated with etanercept. METHODS:53 patients with JIA from seven Dutch centres were included. HRQoL was measured by the Childhood Health Assessment Questionnaire (CHAQ),...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1136/ard.2009.111260

    authors: Prince FH,Geerdink LM,Borsboom GJ,Twilt M,van Rossum MA,Hoppenreijs EP,Cate RT,Koopman-Keemink Y,van Santen-Hoeufft M,Raat H,van Suijlekom-Smit LW

    更新日期:2010-01-01 00:00:00

  • Urinary albumin excretion in patients with systemic lupus erythematosus without renal disease.

    abstract:OBJECTIVES:To investigate the prevalence of microalbuminuria, urinary albumin excretion (UAE) between 20-200 micrograms/min, in systemic lupus erythematosus (SLE) patients without clinical renal disease, and to discover if this could predict the development of renal disease. METHODS:This study made six monthly measure...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.56.6.386

    authors: Batlle-Gualda E,Martínez AC,Guerra RA,Pascual E

    更新日期:1997-06-01 00:00:00

  • Effect of home-based hand exercises in women with hand osteoarthritis: a randomised controlled trial.

    abstract:BACKGROUND:Hand exercises are recommended for patients with hand osteoarthritis (HOA), though evidence for their effect is conflicting. OBJECTIVE:To evaluate, in a randomised controlled trial, the effect of HOA information plus home-based hand exercises (exercise group) compared with information only (control group) i...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章,随机对照试验

    doi:10.1136/annrheumdis-2013-204808

    authors: Hennig T,Hæhre L,Hornburg VT,Mowinckel P,Norli ES,Kjeken I

    更新日期:2015-08-01 00:00:00

  • Effect of intra-articular corticosteroid injections on primate cartilage.

    abstract::An attempt was made to ascertain whether intra-articular corticosteroids exert a harmful effect on primate cartilage. The knee joints of 10 Macaca irus monkeys were subjected to either one, two, or six injections of 20 mg methyl prednisolone or an equal number of control injections over a 12-week period. Minor degener...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.36.1.74

    authors: Gibson T,Burry HC,Poswillo D,Glass J

    更新日期:1977-02-01 00:00:00

  • Circulating immune complexes and rheumatoid arthritis: a comparison of different assay methods and their early predictive value for disease activity and outcome.

    abstract::The performance of four different assays for circulating immune complexes-the C1q solid phase method, one using protein A and one using anti-IgG, C1q PEG, and the 2% PEG method-were compared in 61 patients with early rheumatoid arthritis followed up for two years. There were weak but statistically significant correlat...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.44.2.79

    authors: Reeback JS,Silman AJ,Holborow EJ,Maini RN,Hay FC

    更新日期:1985-02-01 00:00:00

  • Musculoskeletal manifestations in polymyalgia rheumatica and temporal arteritis.

    abstract:OBJECTIVE:To evaluate the incidence and characteristics of musculoskeletal manifestations in polymyalgia rheumatica (PMR) and temporal arteritis (TA). METHODS:The records of 163 cases of PMR or TA diagnosed over a 15 year period in one area of Spain were reviewed for the presence and type of musculoskeletal manifestat...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.60.11.1060

    authors: Narváez J,Nolla-Solé JM,Narváez JA,Clavaguera MT,Valverde-García J,Roig-Escofet D

    更新日期:2001-11-01 00:00:00

  • Raised monocyte chemotactic protein-1 (MCP-1)/CCL2 in cerebrospinal fluid of patients with neuropsychiatric lupus.

    abstract:BACKGROUND:An imbalance in cytokine homoeostasis is thought to have a key role in the neuropsychiatric syndromes of systemic lupus erythematosus (NPSLE), and recently, a role for chemokines has been noted. OBJECTIVE:To compare concentrations of monocyte chemotactic protein-1 (MCP-1)/CCL2 in cerebral spinal fluid (CSF)...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.2005.041640

    authors: Iikuni N,Okamoto H,Yoshio T,Sato E,Kamitsuji S,Iwamoto T,Momohara S,Taniguchi A,Yamanaka H,Minota S,Kamatani N

    更新日期:2006-02-01 00:00:00