Abstract:
:The purpose of this study was to quantify any age-related change in the components of Schwann cells associated with vestibular ganglion cells: adperikaryonal Schwann cell cytoplasm, myelin bubbles, compact myelin, Schwann cell lipofuscin, or mitochondria in addition to extracellular intraganglionic space. Studies were carried out in young (Y, 3 to 5 months of age, N = 6), old (0, 24 to 26 months of age, N = 3), and very old (VO, 28 to 31 months of age, N = 6) female Wistar rats using point counting stereologic techniques. Recent reports have demonstrated age-related increases in the peripheral nerve counterparts to the following entities: adaxonal Schwann cell cytoplasm, myelin bubble, endoneurial space, and a decrease in Schwann cell mitochondria. Our results indicate no age-related change in the volume fraction of extracellular intraganglionic space (Y, 0.179 +/- 0.04; O, 0.174 +/- 0.049; VO, 0.205 +/- 0.043), adperikaryonal Schwann cell cytoplasm (Y, 0.026 +/- 0.008; O, 0.019 +/- 0.003; VO; 0.028 +/- 0.007), myelin bubble (Y, 0.004 +/- 0.003; O, 0.011 +/- 0.009; VO, 0.006 +/- 0.002), Schwann cell lipofuscin (Y, 0.002 +/- 0.001; O, 0.004 +/- 0.003; VO, 0.002 +/- 0.001), or mitochondria (Y, 0.194 +/- 0.019; O, 0.208 +/- 0.024; VO, 0.205 +/- 0.04). The only age-related change was an increase in compact myelin (Y, 0.006 +/- 0.001; O, 0.008 +/- 0.006; VO, 0.011 +/- 0.004). These findings differ from those of the peripheral nerve.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Am J Otolaryngoljournal_title
American journal of otolaryngologyauthors
Carney ME,Lyon MJdoi
10.1016/0196-0709(90)90082-7subject
Has Abstractpub_date
1990-07-01 00:00:00pages
228-35issue
4eissn
0196-0709issn
1532-818Xpii
0196-0709(90)90082-7journal_volume
11pub_type
杂志文章abstract:PURPOSE:Laryngeal papillomatosis is the most common benign tumor of the larynx of children. It is characterized by the development of exophytic proliferative lesions in the mucosa of the airways. Human papillomavirus (HPV) has been recognized as a causal agent among which HPV types 6 and 11 are the most frequently impl...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2019.02.003
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the added value of diffusion weighted magnetic resonance imaging (DW-MRI) in characterization of salivary gland lesions. STUDY DESIGN:A prospective study was carried out between January 2013, and March 2015. METHODS:The study included 46 patients. The consultant radiologist, who reviewed the sca...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2016.09.002
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:To determine whether inclusion of chemoradiation history increases estimated risk for complications following total laryngectomy using the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) Surgical Risk Calculator. MATERIALS AND METHODS:A retrospective review of 96 patients wit...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2017.11.005
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:Middle ear disease is increasingly being managed via transcanal endoscopic ear surgery (TEES). A limitation of TEES is that it restricts the surgeon to single-handed dissection. One solution to this would be an endoscope holder to facilitate two-handed dissection. Current endoscope holders are stationary, and c...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102875
更新日期:2020-12-29 00:00:00
abstract::A regional random pattern flap is described which may be used to cover the mastoid area in cases in which the inferior auricle and adjacent tissue have been removed by trauma or surgery. The viability of this vascularized tissue offers a distinct advantage over skin grafting when protection of exposed facial nerve and...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(88)80032-2
更新日期:1988-09-01 00:00:00
abstract:OBJECTIVES:Studies suggest that hypercholesterolemia promotes the development of inner ear disorders such as tinnitus. However, the underlying pathomechanisms are still not clearly defined. METHODS:A retrospective study was performed to assess whether a reduction of serum cholesterol by 3-hydroxy-3-methylglutaryl coen...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2009.09.004
更新日期:2011-01-01 00:00:00
abstract::The management of a patient with traumatic disruption of the cricotracheal junction in an attempted suicide by hanging is described. Such injury is uncommon, and many patients die at the scene; detailed radiologic imaging is rare because of the urgency of airway management. The delayed complete disruption of the major...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2003.11.001
更新日期:2004-05-01 00:00:00
abstract:PURPOSE:The current loss to follow-up rate after failed newborn hearing screening (NBHS) is 34.4%. Previous studies have found that lack of parental and primary care provider (PCP) awareness of NBHS results are significant contributors to loss to follow-up. The objective of this study was to identify factors associated...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102614
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Pneumocephalus is a rare complication of endoscopic sinus surgery (ESS) and microscopic skull base surgery (MSBS). Postoperatively, patients often present with headache and altered mental status. Unrepaired leaks are associated with an increased risk of ascending meningitis. Standard treatment of pneumocepha...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2009.02.012
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVES:To review our results with elective superior mediastinal dissections for thyroid carcinomas. STUDY DESIGN:Retrospective review. METHODS:We searched operative case logs for all patients with thyroid carcinoma treated with an elective superior mediastinal dissection by the senior author (Y.D.) during a 6-yea...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2008.05.003
更新日期:2009-07-01 00:00:00
abstract:PURPOSE:In this article, we study the use of the American Academy of Otolaryngology-Head and Neck Surgery recommendations regarding coagulation screening tests before tonsillectomy and adenoidectomy by ear, nose, and throat (ENT) physicians in Israel and offer insights into the reasons for accepting/declining this reco...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2004.02.002
更新日期:2004-07-01 00:00:00
abstract:PURPOSE:The objective of this study is to determine the results of functional endoscopic sinus surgeries (FESS) for chronic rhinosinusitis with polyps and assess the association between surgery and specific quality of life outcomes. MATERIALS AND METHODS:A prospective study was performed in a tertiary referral center....
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2014.09.003
更新日期:2015-01-01 00:00:00
abstract::Sarcoidosis is a systemic chronic granulomatous disease of unknown etiology. Although it most commonly affects African-Americans, Scandinavians, and the Irish, individuals of all races and ethnicities are susceptible. The otolaryngologist will most frequently encounter sarcoidosis involving the sinonasal region; howev...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1053/ajot.2002.28783
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:We treated allergic rhinitis with trichloroacetic acid (TCA) applied to the inferior turbinates. Further clinical evaluations were made to determine the effect of TCA application on symptoms of allergic rhinitis. We also report the results of measurement of the mucociliary transit time (saccharin time) and nasa...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2006.12.006
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:1. Describe the presentation, imaging, and outcome of two cases of paraganglioma of the facial canal at our institution. 2. Summarize existing literature to better understand this lesion. 3. Clarify terminology. METHODS:Retrospective chart review at single tertiary academic referral center. Literature review u...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/j.amjoto.2014.08.006
更新日期:2014-11-01 00:00:00
abstract::Meniere's disease is a peripheral audiovestibular disorder characterized by vertigo, hearing loss, tinnitus, and aural fullness. Management of these symptoms includes medical and surgical treatment. Many patients with Meniere's disease can be managed using nonablative therapy, such as intratympanic steroids and endoly...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/j.amjoto.2020.102817
更新日期:2021-01-01 00:00:00
abstract::The temporal bones of a newborn infant with hydantoin syndrome showed multiple middle ear and inner ear anomalies. There was a constellation of bony and membranous defects involving the oval and round windows, cochlear ducts, cochlear aqueducts, endolymphatic ducts and sacs, and vestibular labyrinths. To the authors' ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(86)80025-4
更新日期:1986-09-01 00:00:00
abstract:OBJECTIVES:The purpose of this study is to characterize the effect of KAI1 overexpression on the biological behavior of nasopharyngeal carcinoma (NPC) cells. BACKGROUND:Nasopharyngeal carcinoma is a highly malignant tumor with a high rate of incidence in China. Currently, there are no ideal therapeutic options for pat...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2016.09.011
更新日期:2017-01-01 00:00:00
abstract::Exercise after vestibular injury is potentially an important modality in the recovery process. In this study, the effects of injury on the vestibular system were examined experimentally in cats. Data from healthy normal cats, labyrinthectomized cats, and labyrinthectomized cats treated with exercise were examined. Eva...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(82)80017-3
更新日期:1982-11-01 00:00:00
abstract:PURPOSE:Despite improved surgical and medical therapies, recurrence remains a significant problem in chronic rhinosinusitis with nasal polyps (CRSwNP), given a recently-reported long-term revision rate of 15%-20%. In this prospective study uni- and multivariate statistical analyses were used to identify clinical, labor...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2015.01.019
更新日期:2015-07-01 00:00:00
abstract::Clinical characteristics of 99 consecutive patients with acquired and perioperatively established aural cholesteatoma were compared with those of 81 patients with chronic otitis without cholesteatoma (controls). The patients answered a questionnaire, and preoperative and perioperative clinical observations were record...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/0196-0709(91)90002-w
更新日期:1991-09-01 00:00:00
abstract::Current indications for TT placement are (1) persistent SOM that has not responded to a 6 to 12-week course of medical treatment. This includes full and prophylactic doses of antimicrobials (and corticosteroids, as indicated); (2) recurrent AOM (at least three episodes in 6 months or four episodes in 12 months) that d...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/0196-0709(94)90058-2
更新日期:1994-03-01 00:00:00
abstract::Acinic cell carcinoma is a rare tumor of the head and neck that mainly affects the parotid gland but occasionally involves the minor salivary glands of the upper aerodigestive tract. The authors present a case report of an occurrence of a low-grade acinic cell carcinoma of the true vocal fold, which they believe to be...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(03)00055-3
更新日期:2003-07-01 00:00:00
abstract:PURPOSE:Cystic masses of the supraclavicular fossa (SCF) are uncommon. The diverse anatomical structures within the SCF create an extended differential diagnosis for any mass arising in the SCF. This study describes the presenting symptoms, radiologic findings, medical and surgical management, and posttreatment outcome...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/j.amjoto.2009.08.008
更新日期:2010-11-01 00:00:00
abstract:PURPOSE:This study aims to report the postoperative complications and management of cochlear implantation in pediatric patients at our institution. All procedures were carried out by a single surgeon utilizing minimally invasive techniques. The impact of past surgical history of tympanostomy tubes was also reviewed to ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2015.09.002
更新日期:2016-01-01 00:00:00
abstract::Volumetric changes of the middle ear and mastoid were measured monthly by the direct volumetric method in 28 ears from 21 patients (12 children and nine adults) with otitis media with effusion. The mean volumetric increase immediately after the insertion of the tubes was 1.56 ml and was attributed to the volume of eff...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(86)80053-9
更新日期:1986-07-01 00:00:00
abstract:OBJECTIVE:The clinical use of aminoglycoside antibiotics is limited in most countries because of auditory toxicity side effects. However, their use is common in developing countries because they are inexpensive and convenient. Salvia miltiorrhiza extracts are used clinically in China for their antioxidant properties. W...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2013.08.022
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:This study was designed for better understanding of the role of different methods of nasal endoscopy in the assessment of adenoid hypertrophy and comparing them with lateral neck radiography and patients' symptoms. SUBJECTS AND METHOD:From August 2007 until January 2009, in the otolaryngology ward of a terti...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2009.11.003
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:To investigate whether the racial/ethnical disparity of nasopharyngeal carcinoma exists among the four major ethical groups in the United States named Asians, Caucasians, African Americans and Hispanics between the years of 1973 to 2013 using the Surveillance, Epidemiology, and End Result (SEER) database. ME...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2019.102288
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To compare the surgical and audiologic success rates of areolar connective tissue with temporalis fascia in pediatric tympanoplasty. METHODS:Retrospective case series review of 10 patients younger than 18 years who underwent primary tympanoplasty between December 1997 and December 2000 using areolar connective...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2003.10.004
更新日期:2004-03-01 00:00:00