Abstract：
:The aim of this study was to assess the frequencies of three hemochromatosis gene (HFE) mutations in ethnic Roma/Gypsies in Slovakia. A cohort of 367 individuals representing general population and not preselected for health status was genotyped by TaqMan real-time PCR assay for C282Y, H63D and S65C mutations in HFE gene. A unique genetic profile was revealed: C282Y is found in the highest frequency of all Central European countries (4.90%), while the frequency of H63D mutation (4.09%) is lower than any reported in Europe so far. S65C mutation was not present in the cohort. These mutation frequencies can be explained rather by gene influx and genetic isolation than by genetic inheritance from a former Roma/Gypsy homeland.
journal_name
J Appl Genetjournal_title
Journal of applied geneticsauthors
Gabriková D,Bernasovská J,Mačeková S,Bôžiková A,Bernasovský I,Bališinová A,Sovičová A,Behulová R,Petrejčíková E,Soták M,Boroňová Idoi
10.1007/s13353-012-0088-ysubject
Has Abstractpub_date
2012-05-01 00:00:00pages
183-7issue
2eissn
1234-1983issn
2190-3883journal_volume
53pub_type
杂志文章abstract：:In this work, a seed-set-based screening was performed on 70 lines of Arabidopsis thaliana after activation tagging mutagenesis to identify mutations in reproductive mechanisms. Five mutants showed significantly lower seed set than the wild type and confirmed the phenotype in the progeny. This phenotype was linked wit...
journal_title：Journal of applied genetics
pub_type： 杂志文章
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更新日期：2006-01-01 00:00:00
abstract：:Genetic relationships among 20 elite wheat genotypes were studied using microsatellite markers and pedigree analysis. A total of 93 polymorphic bands were obtained with 25 microsatellite primer pairs. Coefficient of parentage (COP) values were calculated using parentage information at the expansion level of 5. The ped...
journal_title：Journal of applied genetics
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更新日期：2005-01-01 00:00:00
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journal_title：Journal of applied genetics
pub_type： 杂志文章
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journal_title：Journal of applied genetics
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journal_title：Journal of applied genetics
pub_type： 杂志文章
doi：10.1007/BF03195710
更新日期：2010-01-01 00:00:00
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journal_title：Journal of applied genetics
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journal_title：Journal of applied genetics
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journal_title：Journal of applied genetics
pub_type： 杂志文章
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journal_title：Journal of applied genetics
pub_type： 杂志文章
doi：10.1007/s13353-010-0015-z
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journal_title：Journal of applied genetics
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pub_type： 杂志文章
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更新日期：2012-02-01 00:00:00
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journal_title：Journal of applied genetics
pub_type： 杂志文章
doi：10.1007/BF03195698
更新日期：2009-01-01 00:00:00
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journal_title：Journal of applied genetics
pub_type： 杂志文章
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journal_title：Journal of applied genetics
pub_type： 杂志文章
doi：10.1007/BF03195609
更新日期：2008-01-01 00:00:00
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journal_title：Journal of applied genetics
pub_type： 杂志文章
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更新日期：2014-11-01 00:00:00
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journal_title：Journal of applied genetics
pub_type： 杂志文章
doi：10.1007/BF03208882
更新日期：2010-01-01 00:00:00
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journal_title：Journal of applied genetics
pub_type： 杂志文章
doi：10.1007/s13353-012-0091-3
更新日期：2012-08-01 00:00:00
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journal_title：Journal of applied genetics
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
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journal_title：Journal of applied genetics
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doi：
更新日期：2003-01-01 00:00:00
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journal_title：Journal of applied genetics
pub_type： 杂志文章
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journal_title：Journal of applied genetics
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journal_title：Journal of applied genetics
pub_type： 杂志文章,评审
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journal_title：Journal of applied genetics
pub_type： 杂志文章
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journal_title：Journal of applied genetics
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journal_title：Journal of applied genetics
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更新日期：2011-05-01 00:00:00
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pub_type： 杂志文章
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journal_title：Journal of applied genetics
pub_type： 杂志文章
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journal_title：Journal of applied genetics
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更新日期：2002-01-01 00:00:00
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journal_title：Journal of applied genetics
pub_type： 杂志文章
doi：
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