Ubiquitous amyloids.

Abstract:

:The common view of amyloids and prion proteins is that they are associated with many currently incurable diseases and present a great danger to an organism. This danger comes from the fact that not only prion proteins, but also the infectious form(s) of amyloids, as it has been shown recently, are able to transmit the disease. On the other hand, organisms take advantage of the strength and durability of specific forms of amyloids. Such forms do not spread any disease. Also, in nanotechnology there is a constantly growing need to employ amyloid fibrils in many industrial applications. With increasing knowledge about amyloids and prion proteins we are aware that the amyloidal state is inherent to any protein, making the problem of amyloid formation a central one in aging-related diseases. However, the "good" amyloids can be beneficial and even necessary for our health. Furthermore, because of their mechanical properties, the amyloids are of great interest to engineers.

authors

Pulawski W,Ghoshdastider U,Andrisano V,Filipek S

doi

10.1007/s12010-012-9549-3

subject

Has Abstract

pub_date

2012-04-01 00:00:00

pages

1626-43

issue

7

eissn

0273-2289

issn

1559-0291

journal_volume

166

pub_type

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