Aberrant expression of EphA3 in gastric carcinoma: correlation with tumor angiogenesis and survival.

abstract：:An expert meeting was organized by the Swedish and Norwegian Medical Products Agencies in September 1995 in order to review the current literature and opinions on detection and treatment of Helicobacter pylori. Ten people from these Agencies and 23 experts participated in the workshop and all were involved in the fina...

journal_title：Journal of gastroenterology

authors： Unge P

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:Single nucleotide polymorphisms (SNPs) of the adiponectin gene have been reported to be associated with insulin resistance and the prevalence of type-2 diabetes. We investigated the SNPs of adiponectin in non-alcoholic fatty liver disease (NAFLD) patients. METHODS:One hundred nineteen patients histologically d...

journal_title：Journal of gastroenterology

authors： Tokushige K,Hashimoto E,Noto H,Yatsuji S,Taniai M,Torii N,Shiratori K

更新日期：2009-01-01 00:00:00

abstract：:We measured urokinase-type plasminogen activator (u-PA) plasma levels in patients with various chronic liver diseases, including hepatocellular carcinoma (HCC), also measuring these levels in healthy volunteers. Plasma u-PA levels in the group of patients with decompensated liver cirrhosis (mean modified Pugh score of...

journal_title：Journal of gastroenterology

authors： Sato S,Higashi T,Ouguchi S,Hino N,Tsuji T

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Liver histology is the gold standard for the diagnosis of nonalcoholic steatohepatitis (NASH). Noninvasive, simple, reproducible, and reliable biomarkers are greatly needed to differentiate NASH from nonalcoholic fatty liver disease (NAFLD). METHODS:To construct a scoring system for predicting NASH, 177 Jap...

journal_title：Journal of gastroenterology

authors： Sumida Y,Yoneda M,Hyogo H,Yamaguchi K,Ono M,Fujii H,Eguchi Y,Suzuki Y,Imai S,Kanemasa K,Fujita K,Chayama K,Yasui K,Saibara T,Kawada N,Fujimoto K,Kohgo Y,Okanoue T,Japan Study Group of Nonalcoholic Fatty Liver Disease

更新日期：2011-02-01 00:00:00

abstract：:This study was designed to clarify what differences the last 25 years have made in surgical results for patients with hepatocellular carcinoma (HCC). We examined results for 716 hepatectomized patients in four treatment eras: first era (1973-1980; n = 58), second era (1981-1985; n = 155), third era (1986-1990; n = 243...

journal_title：Journal of gastroenterology

authors： Yamanaka N,Takata M,Tanaka T,Yamanaka J,Yasui C,Ando T,Kuroda N,Maeda S,Okamoto E

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Vaniprevir is a potent macrocyclic hepatitis C virus (HCV) nonstructural protein 3/4A protease inhibitor. This phase III study evaluated the safety and efficacy of vaniprevir in combination with peginterferon alfa-2b and ribavirin (PR) for 24 weeks compared with PR alone for 48 weeks in treatment-naive Japan...

journal_title：Journal of gastroenterology

authors： Hayashi N,Nakamuta M,Takehara T,Kumada H,Takase A,Howe AY,Ludmerer SW,Mobashery N

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:The dynamic change in gastric emptying on a minute-by-minute basis (gastric velocity) is evaluated by the 13C-octanoate breath test with deconvolution analysis. However, deconvolution is impractical, because it requires dual experiments to obtain 13CO2 excretion profiles following intraduodenal and oral admi...

journal_title：Journal of gastroenterology

authors： Sanaka M,Yamamoto T,Osaki Y,Kuyama Y

更新日期：2006-07-01 00:00:00

abstract：:Aberrant methylation of CpG islands in promoter regions can permanently inactivate tumor-suppressor genes, as mutations and chromosomal abnormalities do. In gastric cancers, CDKN2A, CDH1, and MLH1 are inactivated more frequently by aberrant methylation than by mutations, and novel tumor-suppressor genes inactivated by...

journal_title：Journal of gastroenterology

authors： Ushijima T,Nakajima T,Maekita T

更新日期：2006-05-01 00:00:00

abstract：:Although polycystic liver disease (PLD) is known to be associated with autosomal dominant polycystic kidney disease, a finding of PLD with pancreatic ductal adenocarcinoma is extremely rare. We have experienced one such case of a ductal adenocarcinoma of the pancreas in a patient with Potter type III cystic disease of...

journal_title：Journal of gastroenterology

authors： Sakurai Y,Shoji M,Matsubara T,Ochiai M,Funabiki T,Urano M,Mizoguchi Y,Fuwa N

更新日期：2001-06-01 00:00:00

abstract：:We investigated the effect of intravenous infusions of the therapeutically available amino acid solutions Moripron and Morihepamin (Roussel Morishita, Osaka, Japan) on gallbladder contraction and cholecystokinin (CCK) release in healthy male volunteers. Plasma CCK levels were measured by radioimmunoassay, using the an...

journal_title：Journal of gastroenterology

authors： Shirohara H,Tabaru A,Otsuki M

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:Recently, guidelines for the treatment and prevention of ulcers induced by non-steroidal anti-inflammatory drugs (NSAIDs) were established. This study investigated the association between the current adherence to the guidelines and the incidence of gastric mucosal lesions caused by NSAIDs. METHODS:This study...

journal_title：Journal of gastroenterology

authors： Tsumura H,Fujita T,Tamura I,Morita Y,Yoshida M,Toyonaga T,Mukai H,Inokuchi H,Kutsumi H,Azuma T

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Fulminant non-A, non-B, non-C hepatitis has a high mortality rate, making the identification of its causative agent imperative. Cytomegalovirus, Epstein-Barr virus, human herpesvirus-6, and herpes simplex virus are all members of the herpesviridae family that are associated with fatal hepatic failure. We inv...

journal_title：Journal of gastroenterology

authors： Ishikawa K,Hasegawa K,Naritomi T,Kanai N,Ogawa M,Kato Y,Kobayashi M,Torii N,Hayashi N

更新日期：2002-01-01 00:00:00

abstract：:Helicobacter pylori infection has been found to decrease the expression of antral somatostatin and to increase the release of the acid-stimulating hormone gastrin. The reversal of these changes in gut hormones by the eradication of H. pylori, and in-vivo and in-vitro studies in animals either infected with H. pylori o...

journal_title：Journal of gastroenterology

authors： Kaneko H,Konagaya T,Kusugami K

更新日期：2002-01-01 00:00:00

abstract：:Nonrotation of the midgut in adults and appendiceal mucocele are both rare pathological conditions. We report here the first case of nonrotation of the midgut associated with appendiceal mucocele. The patient was a 51-year-old man admitted to hospital with ileus. An upper gastrointestinal series and a barium enema rev...

journal_title：Journal of gastroenterology

authors： Kawashima K,Ishihara S,Amano K,Hirakawa K,Adachi K,Fukuda R,Sumi S,Watanabe M,Kinoshita Y

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Acute liver failure is a potentially fatal disease of various etiologies for which liver transplantation is the only known curative treatment. Although the decision-making on transplantation is largely dependent on the severity of liver injury (based on predicting a fatal outcome), a statistical analysis to ...

journal_title：Journal of gastroenterology

authors： Mawatari S,Moriuchi A,Ohba F,Kawano T,Oda K,Takikawa Y,Takikawa H,Ido A,Tsubouchi H

更新日期：2018-07-01 00:00:00

abstract：:Human glucagonoma cells were isolated and maintained in vitro. Incubation experiments showed that carbachol (Cch) induced the simultaneous release of glucagon, VIP (vasoactive intestinal polypeptide), and pancreatic polypeptide (PP) at levels significantly higher than basal levels. Atropine abolished the stimulatory e...

journal_title：Journal of gastroenterology

authors： Funakoshi A,Yasunami Y,Ryu S,Shinozaki H,Jimi A,Ikeda S

更新日期：1994-12-01 00:00:00

abstract：:We encountered a patient with a ciliated hepatic foregut cyst with accompanying liver cirrhosis, which was hard to distinguish from well-differentiated hepatocellular carcinoma. A lesion 2 cm in diameter was found in the subcapsular region of the medial segment of the liver. It was slightly hypoechoic on ultrasonograp...

journal_title：Journal of gastroenterology

authors： Murakami T,Imai A,Nakamura H,Tsuda K,Kanai T,Wakasa K

更新日期：1996-06-01 00:00:00

abstract：:This study aimed to investigate sex differences in relation to hepatitis B e antigen (HBeAg) and serum alanine aminotransferase (ALT) levels in chronic asymptomatic hepatitis B virus (HBV) infection. HBeAg and ALT level were determined in 636 asymptomatic hepatitis B surface antigen carriers. There was no significant ...

journal_title：Journal of gastroenterology

authors： Tsai JF,Chuang LY,Jeng JE,Ho MS,Lin ZY,Hsieh MY,Wang LY,Tsai JH

更新日期：2000-01-01 00:00:00

abstract：:A 21-year-old man with diarrhea and edema was admitted to our hospital and diagnosed with protein-losing enteropathy caused by primary intestinal lymphangiectasia. He was placed, in turn, on a low-fat diet, an elemental diet, and, subsequently, fasting therapy with total parenteral nutrition (TPN) support. However, hi...

journal_title：Journal of gastroenterology

authors： Kuroiwa G,Takayama T,Sato Y,Takahashi Y,Fujita T,Nobuoka A,Kukitsu T,Kato J,Sakamaki S,Niitsu Y

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Although pancreatic duct guidewire placement (P-GW) for achieving selective biliary cannulation is reported to be effective in patients in whom endoscopic retrograde cholangiopancreatography (ERCP) is difficult, this technique entails a possible increased risk of post-ERCP pancreatitis. We conducted a prospe...

journal_title：Journal of gastroenterology

authors： Ito K,Fujita N,Noda Y,Kobayashi G,Obana T,Horaguchi J,Takasawa O,Koshita S,Kanno Y,Ogawa T

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The levels of serum HER2 extracellular domain (ECD) are highly correlated with tissue HER2 status in metastatic gastric cancer (AGC). We sought to explore whether serum HER2 ECD could predict the efficacy of trastuzumab-treated HER2-positive AGC. MATERIALS AND METHODS:From 2011 to 2013, trastuzumab-treated ...

journal_title：Journal of gastroenterology

authors： Zhou J,Peng Z,Liu Y,Gong J,Zhang X,Lu M,Gao J,Li Y,Li Y,Shen L

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) core protein is known to cause oxidative stress and alter apoptosis pathways. However, the apoptosis results are inconsistent, and the real significance of oxidative stress is not well known. The aim of this study was twofold. First, we wanted to confirm whether core-induced oxidative...

journal_title：Journal of gastroenterology

authors： Hara Y,Hino K,Okuda M,Furutani T,Hidaka I,Yamaguchi Y,Korenaga M,Li K,Weinman SA,Lemon SM,Okita K

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:The relative contribution of gastric acid secretion and Helicobacter pylori infection to low-dose aspirin-induced gastropathy remains to be clarified. This is partly because the capability of the infection to modify gastric acid secretion complicates the interaction. The aim of this study was to estimate the...

journal_title：Journal of gastroenterology

authors： Iijima K,Ara N,Abe Y,Koike T,Iwai W,Uno K,Asano N,Imatani A,Ohara S,Shimosegawa T

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:In acute pancreatitis, pancreatic phospholipase A(2) (PLA2) in the circulating blood hydrolyzes phospholipids contained in plasma lipoproteins, liberating eicosanoid precursors that are subsequently converted to various eicosanoids. The pathophysiological significance of eicosanoid synthesis via this pathway...

journal_title：Journal of gastroenterology

authors： Motoyoshi M,Sugiyama M,Atomi Y,Kimura W,Nagawa H

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND AND AIM:Mac-2 Binding Protein Glycosylation Isomer (M2BPGi) is a novel fibrosis marker. We examined the ability of M2BPGi to predict liver fibrosis in patients with biliary atresia. METHODS:Sixty-four patients who underwent living donor liver transplantation (LDLT) were included [median age, 1.1 years (rang...

journal_title：Journal of gastroenterology

authors： Yamada N,Sanada Y,Tashiro M,Hirata Y,Okada N,Ihara Y,Urahashi T,Mizuta K

更新日期：2017-02-01 00:00:00

abstract：:Various types of polyunsaturated fatty acids (PUFAs) have been suggested to exert different effects on the colon in terms of promotion or inhibition of tumor development. Results of in vitro and in vivo studies are, however, inconsistent and it remains unclear whether or not the cellular effects of PUFAs change along ...

journal_title：Journal of gastroenterology

authors： Tsai WS,Nagawa H,Kaizaki S,Tsuruo T,Muto T

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Gastric marker mucins (MUC5AC and MUC6) and intestinal marker molecules (MUC2 and CD10) have been used to determine the cell lineage of epithelial cell of gastric carcinoma (GC). METHODS:To clarify the characteristics of Epstein-Barr virus (EBV)-associated GC, 18 cases were immunohistochemically evaluated a...

journal_title：Journal of gastroenterology

authors： Barua RR,Uozaki H,Chong JM,Ushiku T,Hino R,Chang MS,Nagai H,Fukayama M

更新日期：2006-08-01 00:00:00

abstract：:Focal nodular hyperplasia (FNH) is a benign lesion of the liver which usually presents with one or two localizations. We report a patient with history of resection of a biliary cyst, and who had been taking oral contraceptives for the past 18 years, who had multiple localizations of FNH (more than 30 lesions). The lar...

journal_title：Journal of gastroenterology

authors： Colle I,de Beeck BO,Hoorens A,Hautekeete M

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:It is controversial whether patients with gastric marginal zone lymphomas of mucosa associated lymphoid tissue (MALT) have higher risk of second malignancies. The aim of this study was to define the risk of second malignancies in these patients. METHODS:We analyzed prospective follow-up data of 146 consecut...

journal_title：Journal of gastroenterology

authors： Tajika M,Matsuo K,Ito H,Chihara D,Bhatia V,Kondo S,Tanaka T,Mizuno N,Hara K,Hijioka S,Imaoka H,Matsumoto K,Nakamura T,Yatabe Y,Yamao K,Niwa Y

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:We aimed to evaluate gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) for the detection of hepatocellular carcinomas (HCCs) and dysplastic nodules (DNs) compared with dynamic multi-detector row computed tomography (MDCT), and to discriminate ...

journal_title：Journal of gastroenterology

authors： Inoue T,Kudo M,Komuta M,Hayaishi S,Ueda T,Takita M,Kitai S,Hatanaka K,Yada N,Hagiwara S,Chung H,Sakurai T,Ueshima K,Sakamoto M,Maenishi O,Hyodo T,Okada M,Kumano S,Murakami T

更新日期：2012-09-01 00:00:00