Damage in the dorsal striatum alleviates addictive behavior.

Abstract:

:The ventral striatum has been assigned a major role in addictive behavior. In addition, clinical lesion studies have described involvement of the insula and globus pallidus. To the best of our knowledge, this is the first report of alleviation of alcohol and nicotine addiction after a cerebrovascular incident in the dorsal striatum. The patient was still abstinent from alcohol and nicotine at follow-up. This observation suggests that the dorsal striatum may play a critical role in addiction to alcohol and nicotine.

journal_name

Gen Hosp Psychiatry

authors

Muskens JB,Schellekens AF,de Leeuw FE,Tendolkar I,Hepark S

doi

10.1016/j.genhosppsych.2012.01.008

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

702.e9-702.e11

issue

6

eissn

0163-8343

issn

1873-7714

pii

S0163-8343(12)00010-2

journal_volume

34

pub_type

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