Abstract:
OBJECTIVE:Patients with factitious disorder (FD) fabricate illness, injury or impairment for psychological reasons and, as a result, misapply medical resources. The demographic and clinical profile of these patients has yet to be described in a sufficiently large sample, which has prevented clinicians from adopting an evidence-based approach to FD. The present study aimed to address this issue through a systematic review of cases reported in the professional literature. METHOD:A systematic search for case studies in the MEDLINE, Web of Science and EMBASE databases was conducted. A total of 4092 records were screened and 684 remaining papers were reviewed. A supplementary search was conducted via GoogleScholar, reference lists of eligible articles and key review papers. In total, 372 eligible studies yielded a sample of 455 cases. Information extracted included age, gender, reported occupation, comorbid psychopathology, presenting signs and symptoms, severity and factors leading to the diagnosis of FD. RESULTS:A total of 66.2% of patients in our sample were female. Mean age at presentation was 34.2 years. A healthcare or laboratory profession was reported most frequently (N=122). A current or past diagnosis of depression was described more frequently than personality disorder in cases reporting psychiatric comorbidity (41.8% versus 16.5%) and more patients elected to self-induce illness or injury (58.7%) than simulate or falsely report it. Patients were most likely to present with endocrinological, cardiological and dermatological problems. Differences among specialties were observed on demographic factors, severity and factors leading to diagnosis of FD. CONCLUSIONS:Based on the largest sample of patients with FD analyzed to date, our findings offer an important first step toward an evidence-based approach to the disorder. Future guidelines must be sensitive to differing methods used by specialists when diagnosing FD.
journal_name
Gen Hosp Psychiatryjournal_title
General hospital psychiatryauthors
Yates GP,Feldman MDdoi
10.1016/j.genhosppsych.2016.05.002subject
Has Abstractpub_date
2016-07-01 00:00:00pages
20-8eissn
0163-8343issn
1873-7714pii
S0163-8343(16)30072-Xjournal_volume
41pub_type
杂志文章,评审abstract::Minicomputer systems have been designed for researchers who have no prior computer experience and, therefore, require no computer training, that is, programming knowledge. Such systems allow immediate access to the data, their retrieval, reduction, and analysis, and the retention of direct control over the data base b...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(85)90021-0
更新日期:1985-04-01 00:00:00
abstract::The Ras-Raf-mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)-ERK cascade is important in the intra-cellular transduction of neurotransmitters, such as dopamine and glutamate. Sorafenib (Nexavar), a multi-kinase inhibitor targeting Raf kinase, vascular endothelial growth factor ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2012.03.001
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:Type D personality, as with formal mental disorders, is linked to increased mortality in coronary heart disease (CHD). Our aim was to determine the prevalence of mental disorders among depressed CHD patients with and without Type D personality. METHODS:Depressive symptoms (HADS, HAM-D), Type D personality (D...
journal_title:General hospital psychiatry
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.genhosppsych.2017.10.001
更新日期:2018-01-01 00:00:00
abstract::The following case presents a 22-year-old woman with relapsing polychondritis and depression treated in liaison, consultation, and outpatient settings by one psychiatrist using a variety of techniques. The discussion focuses on the implications of the case for integrated medical model and psychotherapeutic care, and f...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(83)90010-5
更新日期:1983-12-01 00:00:00
abstract:INTRODUCTION:Intimate partner violence (IPV) is a common form of violence experienced by pregnant women and is believed to have adverse mental health effects postnatally. This study investigated the association of postnatal depression (PND) and suicidal ideation with emotional, physical and sexual IPV experienced by wo...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2015.10.005
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To assess the following among women hospitalized antenatally due to high-risk pregnancies: (1) rates of depression symptoms and anxiety symptoms, (2) changes in depression symptoms and anxiety symptoms and, (3) rates of mental health treatment. METHODS:Sixty-two participants hospitalized for high-risk obstet...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2014.07.011
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To report a case of Alzheimer's disease (AD) following mild traumatic brain injury (TBI). METHOD:Case report. RESULTS:We report the time course of AD following mild TBI with evidence of AD pathology. A patient complained of minor memory disturbance 6 months after TBI and was diagnosed with mild cognitive im...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2014.09.016
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:This study examined the differences in the level of perceived helpfulness of treatments received for a major depressive episode (MDE) from a general medical provider only, a specialty mental health provider only or both. METHOD:This study examined a sample of 8900 respondents from the 2008-2012 National Surv...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2015.04.006
更新日期:2015-07-01 00:00:00
abstract::A 32-year-old female with a seven year history of multiple sclerosis was hospitalized due to an exacerbation of symptoms, and complained of a high frequency of urination and occasional urinary incontinence. A urologic consult was obtained and the patient was diagnosed as having neurogenic (spastic) bladder, resulting ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(82)90022-6
更新日期:1982-04-01 00:00:00
abstract:OBJECTIVE:Factors determining community tenure (CT) between subsequent referrals to a psychiatric emergency room (PER) are only partly understood. We investigated the differential effect of patient and health system characteristics on the CT of patients with a previous referral to a PER. METHOD:Data were collected for...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2005.04.003
更新日期:2005-07-01 00:00:00
abstract::We report on the case of a patient with acquired immune deficiency syndrome- and Cryptococcus neoformans meningitis-related mania in which olanzapine was successfully used adjunctively and transiently to antifungal therapy. ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2010.11.004
更新日期:2011-05-01 00:00:00
abstract::During a 3-month period, determinants of psychotropic drug utilization (sex, age, length of stay, reason for admission, disease severity) and data on psychotropic consumption (type of medication--antidepressants, benzodiazepines and antipsychotics--dosage and length of treatment) were retrospectively collected in a ge...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/s0163-8343(98)00048-6
更新日期:1998-11-01 00:00:00
abstract::Both electroconvulsive therapy (ECT) and paliperidone (PLP) can induce, though infrequently, severe cardiac side-effects. Thus far, no studies are available on the cardiac safety of their co-administration. We report on the cardiac safety of the ECT-PLP combination in nine female inpatients who underwent this treatmen...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2010.09.012
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To determine the validity of a 50% drop in the 20-item Symptom Checklist Depression Scale (SCL-20) score against the "gold standard" of no longer meeting criteria for major depression as assessed using a diagnostic interview in an outpatient cancer population and also to examine the validity of other potentia...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2010.01.001
更新日期:2010-05-01 00:00:00
abstract::The authors present a case of dietary vitamin B12 deficiency in a patient with multiple sclerosis. A simple schemata for evaluating patients for vitamin B12 deficiency is included as a clinical aid for physicians. ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(94)90105-8
更新日期:1994-05-01 00:00:00
abstract:OBJECTIVES:Patients with acute-on-chronic liver failure (ACLF) experience long-term chronic liver diseases plus an acute liver function decompensation. This study aimed to determine whether psychological symptoms in patients with hepatitis B virus (HBV)-related ACLF differ from those with other chronic liver diseases a...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2011.11.012
更新日期:2012-05-01 00:00:00
abstract::A study was conducted of all 51 patients admitted on 64 occasions with self-inflicted burns to the Welsh Regional Burns Unit between January 1979 and January 1991. Two different groups of patients were identified, namely, patients who attempted suicide and patients with self-mutilative behavior. Their differences on a...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(92)90007-w
更新日期:1992-11-01 00:00:00
abstract:OBJECTIVE:This article reviews all available literature concerning the implications of Type D personality (the conjoint effects of negative affectivity and social inhibition) among patients with noncardiovascular conditions. METHODS:Published papers were included if they studied Type D personality among noncardiovascu...
journal_title:General hospital psychiatry
pub_type: 杂志文章,评审
doi:10.1016/j.genhosppsych.2009.09.010
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To compare the prevalence of diagnosed ocular disease and eye disease treatment between Veteran's Administration (VA) patients with and without serious mental illness (SMI). METHODS:Retrospective comparison of diagnosed ocular disease and treatment prevalence among patients with and without diagnosed SMI in ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2016.08.003
更新日期:2016-01-01 00:00:00
abstract::Factitious disorder by proxy (FDP) is a form of abuse in which a caregiver surreptitiously simulates or induces illnesses in a person for whom he or she cares. Typically, a mother is the perpetrator and at least one of her children is victimized. FDP has a high morbidity and mortality rate, and a knowledgeable health ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(95)00127-1
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to determine the effect of adjuvant light therapy with antipsychotic treatment in patients with delirium. METHODS:Thirty-six patients were referred to the consulting psychiatry division of our hospital for a disturbance in consciousness. The patients were randomized to risperido...
journal_title:General hospital psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.genhosppsych.2012.05.003
更新日期:2012-09-01 00:00:00
abstract::Efforts to improve the care of depression in primary care patients have largely ignored the potential of obstetrics/gynecology (OB/GYN) practices. We describe feasibility studies of a depression screening and care management intervention in three diverse OB/GYN practices. Patients were screened using the Patient Healt...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/s0163-8343(03)00006-9
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:The 10-item Center for the Epidemiological Studies of Depression Short Form (CES-D-10) is a widely used self-report measure of depression symptomatology. The aim of this study is to investigate the psychometric properties of the CES-D-10 in healthy community dwelling older adults. METHODS:The sample consist...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2017.08.002
更新日期:2018-01-01 00:00:00
abstract::Ziconotide is used intrathecally in the management of severe chronic pain that contains a warning against neuropsychiatric adverse events. The definition of psychiatric events is broad and management strategies are vague. This case report describes a 49-year-old female who was admitted to the acute psychiatric unit to...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2014.10.001
更新日期:2015-01-01 00:00:00
abstract::Preoperative risk factors of postoperative delirium were evaluated in 260 patients admitted for open heart surgery. The incidence of delirium was 11.5%. Independent predictors included cognitive impairment, atrial fibrillation, a history of peripheral vascular disease major depression and advanced age. Aforementioned ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2006.08.007
更新日期:2006-11-01 00:00:00
abstract::This study reports DSM-III diagnoses and demographic characteristics of 100 patients consecutively referred to a university hospital consultation-liaison service for evaluation of medically unexplained symptoms suggesting physical disorders. Thirty-seven percent of patients received diagnoses of somatoform, dissociati...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(85)90006-4
更新日期:1985-01-01 00:00:00
abstract::Persistent somatization patients put a serious burden on the health care system with multiple admissions, tests, surgeries, and medications. This study reports on factors relevant to the health-seeking behavior of somatizing patients and aspects of the health care system that facilitate their overutilization of health...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(93)90035-m
更新日期:1993-07-01 00:00:00
abstract::A 48-year-old woman with head and neck pain and upper extremity weakness demonstrated equivocal neurologic findings and otherwise essentially negative laboratory and x-ray evaluations. An interview at a case conference revealed significant depression, severe marital discord, and a poor self-image. The correlation of t...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(80)90087-0
更新日期:1980-12-01 00:00:00
abstract::Catatonia is a rare syndrome that occurs in mood and psychotic disorders, and general medical conditions. Postpartum depression affects 10%-15% of women within 6 months after delivery. Postpartum psychosis affects 0.1%-0.5% of women within weeks after delivery, though it can occur within hours; it carries risk for sui...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2011.11.010
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to examine the extent of health care utilisation (excluding costs) of diabetic patients with and without depressive symptoms attending a specialist clinic in Singapore. METHODS:A total of 537 Asian outpatients (aged 21 years and above) who were attending a Diabetes Centre were...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2009.01.001
更新日期:2009-05-01 00:00:00