Severity scoring in the critically ill: part 2: maximizing value from outcome prediction scoring systems.

abstract：STUDY OBJECTIVE:To determine the extent to which rapid on-site cytologic evaluation (ROSE) of transbronchial needle aspiration (TBNA) samples can safely and cost-effectively reduce the need for additional biopsy during bronchoscopy. SETTING:University Hospital in Long Island, NY. PATIENT AND METHODS:Forty-four bronch...

journal_title：Chest

authors： Baram D,Garcia RB,Richman PS

更新日期：2005-08-01 00:00:00

abstract：:Clonidine was given to patients with essential hypertension, renovascular hypertension, and hypertension with parenchymal renal disease. The drug was effective in all groups but was more effective in patients with high plasma renin concentration. Renal function did not deteriorate when the drug was used, and there was...

journal_title：Chest

authors： Morgan T

更新日期：1983-02-01 00:00:00

abstract：:Cocaine use is associated with adverse events in nearly every organ system. Cardiovascular complications include hemorrhagic and ischemic stroke, aortic dissection, cardiomyopathy, accelerated coronary artery disease, myocardial infarction, and sudden cardiac death. Syncope may be the presenting symptom in these condi...

journal_title：Chest

authors： Castro VJ,Nacht R

更新日期：2000-01-01 00:00:00

abstract：:The ventilator discontinuation process is a critical component of ICU care. Ongoing ventilator dependency is caused by both disease factors (eg, respiratory, cardiac, metabolic, and neuromuscular) and clinician management factors (eg, failing to recognize discontinuation potential and inappropriate ventilator settings...

journal_title：Chest

authors： MacIntyre N

更新日期：2007-09-01 00:00:00

abstract：STUDY OBJECTIVE:To investigate the role of oropharyngeal and cutaneous commensal microorganisms (OCCs) as a cause of ventilator-associated pneumonia (VAP). DESIGN:Retrospective analysis of the medical and microbiological records. SETTING:One medical-surgical ICU. PATIENTS:All VAP episodes recorded during a 10-year p...

journal_title：Chest

authors： Lambotte O,Timsit JF,Garrouste-Orgeas M,Misset B,Benali A,Carlet J

更新日期：2002-10-01 00:00:00

abstract：STUDY OBJECTIVE:Depressive symptoms and reduced health-related quality of life are common in patients with severe COPD. Therefore, understanding the association between preferences for life-sustaining treatment and depression or quality of life is important in providing care. No prior studies have examined the effects ...

journal_title：Chest

authors： Stapleton RD,Nielsen EL,Engelberg RA,Patrick DL,Curtis JR

更新日期：2005-01-01 00:00:00

abstract：:Patients with cystic fibrosis (CF) and advanced pulmonary disease have pulmonary limitation of exercise, often associated with arterial oxygen desaturation. Improving oxygenation during exercise by providing supplemental oxygen may improve exercise performance in these patients. To test this, we performed graded exerc...

journal_title：Chest

authors： Marcus CL,Bader D,Stabile MW,Wang CI,Osher AB,Keens TG

更新日期：1992-01-01 00:00:00

abstract：:Body position can lead to respiratory symptoms and affect gas exchange in disease states. We describe a patient with carcinoma of the left lung in whom dyspnea and oxygen desaturation developed in the right lateral position only. Fiberoptic bronchoscopic study demonstrated a tumor mass protruding into the left main-st...

journal_title：Chest

authors： Mahler DA,Snyder PE,Virgulto JA,Loke J

更新日期：1983-05-01 00:00:00

abstract：:Bronchopulmonary C-fibers and a subset of mechanically sensitive, acid-sensitive myelinated sensory nerves play essential roles in regulating cough. These vagal sensory nerves terminate primarily in the larynx, trachea, carina, and large intrapulmonary bronchi. Other bronchopulmonary sensory nerves, sensory nerves inn...

journal_title：Chest

authors： Canning BJ,Chang AB,Bolser DC,Smith JA,Mazzone SB,McGarvey L,CHEST Expert Cough Panel.

更新日期：2014-12-01 00:00:00

abstract：:Transbronchial lung biopsy (TBB) was performed during fiberoptic bronchoscopy under fluoroscopic guidance in 107 patients. TBB was diagnostic in 17 of 21 (81 percent) cases with localized malignant lesions greater than 4 cm in diameter and bronchial brushing was positive in 12 (57 percent). TBB was diagnostic in 14 of...

journal_title：Chest

authors： Ellis JH Jr

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:Heparin-induced thrombocytopenia (HIT) is an antibody-mediated adverse drug reaction that can lead to devastating thromboembolic complications, including pulmonary embolism, ischemic limb necrosis necessitating limb amputation, acute myocardial infarction, and stroke. METHODS:The methods of this guideline f...

journal_title：Chest

authors： Linkins LA,Dans AL,Moores LK,Bona R,Davidson BL,Schulman S,Crowther M

更新日期：2012-02-01 00:00:00

abstract：:Preoperative evaluation of patients being considered for pulmonary resection is a common practice for both pulmonologists and internists. Traditionally, preoperative evaluation of this population has entailed identifying patients in whom pulmonary resection carries an unacceptably high risk of morbidity and mortality....

journal_title：Chest

authors： Reilly JJ

更新日期：1997-10-01 00:00:00

abstract：:As an aid in the differential diagnosis of exudative pleural effusions, tumor markers were investigated. We measured immunosuppressive acidic protein (IAP), carbohydrate antigen 19-9 (CA 19-9), tissue polypeptide antigen (TPA), carcinoembryonic antigen (CEA), adenosine deaminase (ADA), and alpha 1-acid glycoprotein (A...

journal_title：Chest

authors： Niwa Y,Kishimoto H,Shimokata K

更新日期：1985-03-01 00:00:00

abstract：STUDY OBJECTIVE:The purpose of this study was to evaluate the diagnostic value of low voltage with PR-segment and ST-T wave changes in determining the amount of clinically silent pericardial effusion detected in a routine echocardiography. DESIGN:Consecutive case series analysis. SETTING:Noninvasive cardiology depart...

journal_title：Chest

authors： Kudo Y,Yamasaki F,Doi T,Doi Y,Sugiura T

更新日期：2003-12-01 00:00:00

abstract：:In experimental animals, conditions which drastically decrease cardiac output may reduce the strength and endurance of respiratory muscles leading to hypercapnic respiratory failure. Because patients with chronic CHF have reduced cardiac output and vital capacity (FVC), we measured PImax and PEmax and maximal handgrip...

journal_title：Chest

authors： Hammond MD,Bauer KA,Sharp JT,Rocha RD

更新日期：1990-11-01 00:00:00

abstract：:Three patients had hypertrophic obstructive cardiomyopathy and coronary artery spasm. The clinical diagnosis of hypertrophic obstructive cardiomyopathy, in all patients, was confirmed by echocardiography and angiography. Significant spasm of the right coronary artery was demonstrated in each patient by selective coron...

journal_title：Chest

authors： Mautner RK,Thomas I,Dhurandhar R,Phillips JH

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:Although alveolar epithelial injury is a major determinant of outcome in patients with acute lung injury, there is no reliable biological marker of alveolar epithelial injury. The primary objective was to determine whether elevated levels of the receptor for advanced glycation end products (RAGE), a marker o...

journal_title：Chest

authors： Briot R,Frank JA,Uchida T,Lee JW,Calfee CS,Matthay MA

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Direct (pulmonary) and indirect (extrapulmonary) ARDS are distinct syndromes with important pathophysiologic differences. The goal of this study was to determine whether clinical characteristics and predictors of mortality differ between direct or indirect ARDS. METHODS:This retrospective observational coho...

journal_title：Chest

authors： Luo L,Shaver CM,Zhao Z,Koyama T,Calfee CS,Bastarache JA,Ware LB

更新日期：2017-04-01 00:00:00

abstract：KEY POINTS:1. Historically, medical ethics focused on the proper conduct of physicians as members of a profession. 2. Bioethics has emerged as a distinct field over the past several decades and has a broader scope than traditional medical ethics. The field of bioethics includes research ethics, public health ethics, or...

journal_title：Chest

authors： Carrese JA,Sugarman J

更新日期：2006-12-01 00:00:00

abstract：:To facilitate the studies in cell biology and drug sensitivity of non-small cell lung cancer, cell samples from 55 patients have been used to establish cell lines in culture using a chemically defined medium (ACL-4). A total of 20 cell lines (36 percent) were directly established and characterized: 14 (44 percent) fro...

journal_title：Chest

authors： Masuda N,Fukuoka M,Takada M,Kudoh S,Kusunoki Y

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Current functional assessments do not allow a reliable assessment of small airways, which are a major site of disease in COPD. Single-breath washout (SBW) tests are feasible and reproducible methods for evaluating small airway disease. Their relevance in COPD remains unknown. METHODS:We performed a cross-se...

journal_title：Chest

authors： Boeck L,Gensmer A,Nyilas S,Stieltjes B,Re TJ,Tamm M,Latzin P,Stolz D

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Emphysema is the only smoking-related disease in which white patients have higher prevalence and higher attributable mortality rates than African-American patients. Epidemiologic studies have not addressed, nor explained, the observed racial differences in emphysema. STUDY OBJECTIVES:To determine whether wh...

journal_title：Chest

authors： Chatila WM,Hoffman EA,Gaughan J,Robinswood GB,Criner GJ,National Emphysema Treatment Trial Research Group.

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Sleep disorders are increasingly associated with insulin resistance, glucose intolerance, and type 2 diabetes mellitus. Whether the metabolic toll imposed by sleep-related disorders is caused by poor-quality sleep or due to other confounding factors is not known. The objective of this study was to examine wh...

journal_title：Chest

authors： Stamatakis KA,Punjabi NM

更新日期：2010-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) frequently involves the pleura with resultant pleural effusion. Previous studies have reported that detection of antinuclear antibodies (ANA) in pleural fluid using animal tissue as substrate was a sensitive and specific method for distinguishing SLE pleural effusions from other etio...

journal_title：Chest

authors： Khare V,Baethge B,Lang S,Wolf RE,Campbell GD Jr

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Cilia line the surface of the respiratory tract and beat in a coordinated wave to protect the lungs against infection. Bardet Biedl Syndrome (BBS) is a rare condition attributed to cilia dysfunction. Murine models of BBS suggest a respiratory phenotype; however, no reports have studied the translation of the...

journal_title：Chest

authors： Shoemark A,Dixon M,Beales PL,Hogg CL

更新日期：2015-03-01 00:00:00

abstract：:Native valve endocarditis normally presents with fever and only later in its course demonstrates dysfunction of the affected valve. We describe a case of endocarditis due to Neisseria subflava, a Gram-negative diplococcal saprophyte of the oral cavity, which was unsuspected clinically and found unexpectedly during a m...

journal_title：Chest

authors： Amsel BJ,Moulijn AC

更新日期：1996-01-01 00:00:00

abstract：:A case of amiodarone pulmonary toxicity (APT) occurring within days of the start of therapy and presenting with hemoptysis is reported. Both the very early onset and the presenting symptom are highly unusual in this entity. Implications in the diagnosis of APT are discussed. ...

journal_title：Chest

authors： Goldstein I,Topilsky M,Segev D,Isakov A,Heller I

更新日期：1997-05-01 00:00:00

abstract：:This study compared the bronchodilator effect in experimental canine asthma of dyphylline administered by aerosol and intravenous routes in doses producing equivalent concentrations of the drug in the plasma. Pulmonary resistance (RL) was calculated from simultaneous measurements of pressure and flow during fixed-volu...

journal_title：Chest

authors： Hirshman CA,Lawyer C,Downes H,Farbood A,Rodgers R,Gerber N

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND:Our study assessed the short-term effect of electrical muscle stimulation (EMS) of the lower extremities on the thenar muscle microcirculation of patients who are critically ill. METHODS:Twenty-nine hospital ICU patients (19 men; mean [+/- SD] age, 58 +/- 19 years; mean acute physiology and chronic health e...

journal_title：Chest

authors： Gerovasili V,Tripodaki E,Karatzanos E,Pitsolis T,Markaki V,Zervakis D,Routsi C,Roussos C,Nanas S

更新日期：2009-11-01 00:00:00

abstract：:The previously unreported association of chronic persistent cough due to a duplication esophageal cyst is presented. The presence of a long history of atopy, bronchitis, and asthma resulted in a delay in diagnosis. When vigorous bronchodilator therapy was unsuccessful, close observation of the patient and review of he...

journal_title：Chest

authors： Bowton DL,Katz PO

更新日期：1984-07-01 00:00:00