Abstract：
OBJECTIVES:To develop a prediction model for kidney transplantation (KT) outcomes specific to older adults with end-stage renal disease (ESRD) and to use this model to estimate the number of excellent older KT candidates who lack access to KT. DESIGN:Secondary analysis of data collected by the United Network for Organ Sharing and U.S. Renal Disease System. SETTING:Retrospective analysis of national registry data. PARTICIPANTS:Model development: Medicare-primary older recipients (aged ≥ 65) of a first KT between 1999 and 2006 (N = 6,988). Model application: incident Medicare-primary older adults with ESRD between 1999 and 2006 without an absolute or relative contraindication to transplantation (N = 128,850). MEASUREMENTS:Comorbid conditions were extracted from U.S. Renal Disease System Form 2728 data and Medicare claims. RESULTS:The prediction model used 19 variables to estimate post-KT outcome and showed good calibration (Hosmer-Lemeshow P = .44) and better prediction than previous population-average models (P < .001). Application of the model to the population with incident ESRD identified 11,756 excellent older transplant candidates (defined as >87% predicted 3-year post-KT survival, corresponding to the top 20% of transplanted older adults used in model development), of whom 76.3% (n = 8,966) lacked access. It was estimated that 11% of these candidates would have identified a suitable live donor had they been referred for KT. CONCLUSION:A risk-prediction model specific to older adults can identify excellent KT candidates. Appropriate referral could result in significantly greater rates of KT in older adults.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Grams ME,Kucirka LM,Hanrahan CF,Montgomery RA,Massie AB,Segev DLdoi
10.1111/j.1532-5415.2011.03652.xsubject
Has Abstractpub_date
2012-01-01 00:00:00pages
1-7issue
1eissn
0002-8614issn
1532-5415journal_volume
60pub_type
社论,多中心研究abstract：OBJECTIVES:To investigate racial and ethnic differences in graft and recipient survival in elderly kidney transplant recipients. DESIGN:Retrospective cohort. SETTING:First-time, kidney-only transplant recipients aged 60 and older of age at transplantation transplanted between July 1996 and October 2010 (N = 44,013). ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.13845
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVES:To characterize emergency department (ED) use by nursing home residents in the United States. DESIGN:Analysis of the National Hospital Ambulatory Medical Care Survey. SETTING:U.S. EDs from 2005 to 2008. PARTICIPANTS:Individuals visiting U.S. EDs stratified according to nursing home residency. MEASUREMENT...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2011.03587.x
更新日期：2011-10-01 00:00:00
abstract：:Physical performance measures, including cardiopulmonary exercise testing (CPXT), are widely used in geriatric practice and aging research. Theoretically, research participants and study personnel could get infected in the closed environment of the exercise laboratory by contact with respiratory droplets from an infec...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.16968
更新日期：2021-01-01 00:00:00
abstract：OBJECTIVES:To investigate the correlation between zopiclone use and risk of hip fracture in elderly adults. DESIGN:Case-control study. SETTING:Claim data from the Taiwan National Health Insurance Program. PARTICIPANTS:Individuals aged 65 and older who experienced their first episode of hip fracture between 1998 and ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.13823
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVES:To examine the association between hospitalization, critical illness, and infection occurring during middle- and late-life and structural brain abnormalities in older adults. DESIGN:Prospective cohort study. SETTING:Atherosclerosis Risk in Communities (ARIC) Study. PARTICIPANTS:A community sample of adult...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15470
更新日期：2018-10-01 00:00:00
abstract：OBJECTIVES:To determine the contribution of cognitive impairment, prefracture functional impairment, and treatment as predictors of functional status and mobility 6 months after discharge from rehabilitation for older adults with hip fracture. DESIGN:Longitudinal. SETTING:Inpatient rehabilitation units of two communi...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.14297
更新日期：2016-08-01 00:00:00
abstract：OBJECTIVES:To determine whether sex differences in large-artery stiffness contribute to the greater prevalence of systolic hypertension in elderly women than in elderly men. DESIGN:During a single visit arterial stiffness was assessed in the unmedicated state using four parameters. PARTICIPANTS:Three hundred seventy-...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2004.52107.x
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVES:To prospectively examine associations between accelerometer-measured physical activity (PA) and mortality in older women, with an emphasis on light-intensity PA. DESIGN:Prospective cohort study with baseline data collection between March 2012 and April 2014. SETTING:Women's Health Initiative cohort in the ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15201
更新日期：2018-05-01 00:00:00
abstract：:The Schulich School of Medicine, University of Western Ontario, Canada, has created a mandatory clerkship in Elder Care that consists of small group seminars, clinical experiences, and an Elder Care manual. This article describes the use of a paper-based log to track students' clinical encounters to determine whether ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2007.01206.x
更新日期：2007-07-01 00:00:00
abstract：:Chronic atrial fibrillation is generally thought to cause stroke by atrial thrombus formation with subsequent embolization. Rheumatic heart disease previously led to most cases of atrial fibrillation, but recent substantial declines in the incidence of rheumatic fever have changed the distribution of causes of atrial ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1985.tb07121.x
更新日期：1985-04-01 00:00:00
abstract：:The current literature on suicide by medicinal overdose among the elderly population of the United States and Britain is discussed. The older white male is a high risk in this regard. Physical and mental illnesses contribute to the problem of suicide among the aged, and some of the drugs prescribed for treatment (e.g....
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1975.tb00218.x
更新日期：1975-07-01 00:00:00
abstract：:A dramatic increase in the number of ethics committees in long-term care facilities (LTCFs) has occurred since 1970 in the 487 nursing homes in Minnesota. Ten percent of the LTCFs had ethics committees which were mostly formed by administrators and nurses. The committees are most often found in large urban facilities ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1987.tb04009.x
更新日期：1987-11-01 00:00:00
abstract：OBJECTIVES:To assess the incidence of chronic illness and its effect on veteran centenarians. DESIGN:Retrospective longitudinal cohort study. SETTING:United States Veterans Affairs Corporate Data Warehouse (CDW). PARTICIPANTS:Community-dwelling veterans born between 1910 and 1915 who survived to at least age 80 (N =...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.14900
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVES:To describe the features of community-acquired pneumonia (CAP) requiring hospitalization in subjects receiving home care. DESIGN:Prospective study from November 15, 2000, to November 14, 2002. SETTING:Six hospitals in the Edmonton, Canada, area. PARTICIPANTS:Two thousand four hundred sixty-four subjects a...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2005.53264.x
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVES:To evaluate the safety and efficacy of donepezil in the management of patients with Alzheimer's disease (AD) residing in nursing home facilities. DESIGN:Twenty-four-week, randomized, multicenter, parallel-group, double-blind, placebo-controlled trial. SETTING:Twenty-seven nursing homes across the United St...
journal_title：Journal of the American Geriatrics Society
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：2001-12-01 00:00:00
abstract：:Older adults with advanced chronic kidney disease (CKD) experience functional impairment that can complicate CKD management. Failure to recognize functional impairment may put these individuals at risk of further functional decline, nursing home placement, and missed opportunities for timely goals-of-care conversation...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.14262
更新日期：2016-10-01 00:00:00
abstract：BACKGROUND:A widely held dictum in aging research is that heterogeneity in health increases with age, but the basis for this claim has not been fully investigated. We examined heterogeneity at different ages across health characteristics to describe variation and trends; we investigated the comparative importance of be...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.16919
更新日期：2020-11-05 00:00:00
abstract：OBJECTIVES:To estimate the incidence of chronic activities of daily living (ADL) disability and to analyze the sociodemographic, health status, adverse lifestyle, and leisure-time physical activity predictors for chronic ADL disability. DESIGN:We recruited a cohort of community-dwelling older people in Taipei, Taiwan,...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1999.tb05231.x
更新日期：1999-09-01 00:00:00
abstract：:Previous studies found changes in regional cerebral blood flow (rCBF) patterns related to both age and various cognitive tasks. However, no study has yet demonstrated a relationship between rCBF and performance on the Luria-Nebraska Neuropsychological Battery (LNNB) in an elderly group. Seventy-nine elderly volunteers...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1984.tb04169.x
更新日期：1984-10-01 00:00:00
abstract：OBJECTIVE:To describe the total cost of pressure ulcer prevention, component costs of each intervention, and the relationship of costs to subjects' risk level. DESIGN:3-month cohort trial. SETTING:A 600-bed, state-supported, long-term care facility. PATIENTS:A total of 539 war veterans, 83% of whom were male; mean a...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1995.tb06095.x
更新日期：1995-05-01 00:00:00
abstract：OBJECTIVE:To determine if pre-complication nutrient intake can be predicted based on an admission assessment. DESIGN:Survey (cross-sectional study). SETTING:Geriatric Rehabilitation Unit (GRU) of a Veterans Administration hospital. PATIENTS:Three-hundred-twelve randomly selected admissions to the GRU. MEASUREMENTS:...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1994.tb04967.x
更新日期：1994-05-01 00:00:00
abstract：OBJECTIVES:To compare the quality of end-of-life care in Medicare Advantage (MA) and traditional Medicare (TM), specifically, receipt and length of hospice care. DESIGN:Retrospective analysis of administrative data. SETTING:Hospice care. PARTICIPANTS:Veterans dually enrolled in the Veterans Health Administration (VH...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15434
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVE:To identify age-related differences in the treatment of patients with acute myocardial infarction. DESIGN:Retrospective cohort study. SETTING:Two university-affiliated medical centers with integrated clinical programs. PATIENTS:329 patients admitted with acute myocardial infarction in 1988-1990 for whom co...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,多中心研究
doi：10.1111/j.1532-5415.1994.tb06553.x
更新日期：1994-08-01 00:00:00
abstract：:A survey of 977 community subjects aged 65 or older identified 719 of them as not impaired in physical health. Of these, 104 (14 percent) perceived their physical status to be poor, whereas 615 (86 percent) accurately perceived it to be unimpaired. There were no significant differences between the two groups with rega...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1979.tb06051.x
更新日期：1979-07-01 00:00:00
abstract：:Frailty is a common and central problem of old age. Recent research has defined frailty as an accumulation of deficits or as a distinct clinical syndrome involving specific comorbid physical disorders and functional impairment, but the psychological aspects of frailty have received little attention. It is proposed tha...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2008.02104.x
更新日期：2009-02-01 00:00:00
abstract：OBJECTIVES:To assess the effect of cardiovascular diseases and risk factors on mortality in individuals with dementia. DESIGN:Systematic review and meta-analysis. English- and Dutch-language studies in PubMed, EMBASE, and PsycINFO databases were searched in April 2014 with hand-searching of in-text citations and no pu...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,meta分析,评审
doi：10.1111/jgs.13835
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVES:To assess the relationship between alcohol intake and mortality in a cohort of women aged 70 and older and to explore the relationship between level of alcohol use and changes in physical and mental health-related quality of life. DESIGN:National longitudinal surveys from 1996 to 2002. SETTING:Community ba...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2006.00837.x
更新日期：2006-09-01 00:00:00
abstract：:The term "plastic surgeon" is oddly uninformative, although it seems likely that most people know what plastic surgeons do. How well can a sample of individuals encountered on the street describe what geriatricians do? To answer this question, we strolled through downtown Baltimore's Inner Harbor, armed with a video c...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.12115
更新日期：2013-03-01 00:00:00
abstract：:To help determine whether or not the elderly are at unusually high risk for hospital-related complications, a study was made of consecutive admissions involving 48 patients less than 65 years old (mean 50.3 years) and 174 patients more than 65 years old (mean 73.1 years). They were prospectively followed during their ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1982.tb02837.x
更新日期：1982-06-01 00:00:00
abstract：OBJECTIVES:To identify factors associated with incomplete bladder emptying in older women with overactive bladder (OAB) symptoms. DESIGN:Retrospective medical records review. SETTING:Urodynamic laboratory at a large academic health care system in the southeast United States. PARTICIPANTS:Medical records from women a...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.13474
更新日期：2015-07-01 00:00:00
