Aging, regional cerebral blood flow, and neuropsychological functioning.

abstract：OBJECTIVE:(1) To establish the range of cerebral atrophy across the adult age spectrum in optimally healthy, rigorously evaluated individuals. (2) To determine, across the age spectrum, the relation of gender and cerebral atrophy (as measured by ventricular enlargement) to cognitive function. DESIGN:Cross-sectional co...

journal_title：Journal of the American Geriatrics Society

authors： Kaye JA,DeCarli C,Luxenberg JS,Rapoport SI

更新日期：1992-03-01 00:00:00

abstract：OBJECTIVES:To determine whether serum calcium is associated with cognitive function in elderly individuals in the general population. DESIGN:Prospective follow-up study of two independent, population-based cohorts. SETTING:The Rotterdam Study (median follow-up 11 years) and the Leiden 85-plus Study (median follow-up ...

journal_title：Journal of the American Geriatrics Society

authors： Schram MT,Trompet S,Kamper AM,de Craen AJ,Hofman A,Euser SM,Breteler MM,Westendorp RG

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:To assess the effect of chronic renal failure (CRF) on quality of life (QOL). DESIGN:Controlled cross-sectional study. SETTING:All 13 dialysis units in the French Lorraine region and six departments of a Nancy hospital. PARTICIPANTS:One hundred sixty-nine older patients with end-stage renal disease (ESRD)...

journal_title：Journal of the American Geriatrics Society

authors： Loos C,Briançon S,Frimat L,Hanesse B,Kessler M

更新日期：2003-02-01 00:00:00

abstract：:Low-income older adults are particularly vulnerable during care transitions. The present study evaluated the effectiveness of a transitional care model in this population. A quasi-experimental design was used to compare outcomes in the intervention group with historical controls at 30, 90, 180, and 365 days after disc...

journal_title：Journal of the American Geriatrics Society

authors： Ohuabunwa U,Jordan Q,Shah S,Fost M,Flacker J

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:To test the hypothesis that sleep disturbances are independently associated with frailty status in older men. DESIGN:Cross-sectional analysis of prospective cohort study. SETTING:Six U.S. centers. PARTICIPANTS:Three thousand one hundred thirty-three men aged 67 and older. MEASUREMENTS:Self-reported sleep...

journal_title：Journal of the American Geriatrics Society

authors： Ensrud KE,Blackwell TL,Redline S,Ancoli-Israel S,Paudel ML,Cawthon PM,Dam TT,Barrett-Connor E,Leung PC,Stone KL,Osteoporotic Fractures in Men Study Group.

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVES:To analyze the effect of smoking, smoking cessation, and other modifiable risk factors on mobility in middle-aged and older Americans. DESIGN:Panel study; secondary data analysis. SETTING:United States (national sample). PARTICIPANTS:The Health and Retirement Study (HRS) includes data on 12,652 Americans ...

journal_title：Journal of the American Geriatrics Society

authors： Ostbye T,Taylor DH Jr,Krause KM,Van Scoyoc L

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To determine if home environmental hazards increase the risk of fall injury events among community-dwelling older persons. DESIGN:Population-based case-control study. SETTING:South Miami Beach, Florida. PARTICIPANTS:270 persons aged 65 years and older who sought treatment at six area hospitals for injuries...

journal_title：Journal of the American Geriatrics Society

authors： Sattin RW,Rodriguez JG,DeVito CA,Wingo PA

更新日期：1998-06-01 00:00:00

abstract：:Catechol-O-methyltransferase (COMT) inhibitors are a new therapeutic option in the treatment of patients with Parkinson's disease. COMT inhibitors act by extending the duration of action of levodopa, thus improving the amount of time a patient can experience benefit from levodopa. COMT inhibitors are only used in conj...

journal_title：Journal of the American Geriatrics Society

authors： Waters C

更新日期：2000-06-01 00:00:00

abstract：:A cohort of 3,595 white women aged 40-77 years was followed for an average of 10 years during which 84 new cases of hip fracture were identified. Triceps skinfold thickness and arm muscle area measured at baseline were examined as possible risk factors for hip fracture controlling for physical activity, height, menopa...

journal_title：Journal of the American Geriatrics Society

authors： Farmer ME,Harris T,Madans JH,Wallace RB,Cornoni-Huntley J,White LR

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:To study advance directives (code status) among subgroups of Asian nursing home residents. DESIGN:Cross-sectional design. PARTICIPANTS AND SETTING:A total of 423 residents of Asian descent (aged >55) from two ethnic nursing homes in Seattle, Washington. METHODS:Chart review was conducted on 423 residents (...

journal_title：Journal of the American Geriatrics Society

authors： Vaughn G,Kiyasu E,McCormick WC

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVES:To determine, using data from the Newcastle 85+ Study, whether there is an association between modern diagnostic criteria for metabolic syndrome (MetS) and cognitive function in very old adults (≥85) and whether inflammation, physical activity, or diabetes mellitus status affects this association. DESIGN:Lo...

journal_title：Journal of the American Geriatrics Society

authors： Harrison SL,Stephan BC,Siervo M,Granic A,Davies K,Wesnes KA,Kirkwood TB,Robinson L,Jagger C

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:Recently revised vaccination recommendations for US adults, aged 65 years and older, include both 23-valent pneumococcal polysaccharide vaccine (PPSV23) and 13-valent pneumococcal conjugate vaccine (PCV13), with PCV13 now recommended for immunocompetent older people based on shared decision making...

journal_title：Journal of the American Geriatrics Society

authors： Wateska AR,Nowalk MP,Lin CJ,Harrison LH,Schaffner W,Zimmerman RK,Smith KJ

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVES:To compare two sarcopenia definitions and examine the relationship between them and lower extremity function and other health related factors using data from the baseline examination of the Health Aging and Body Composition (Health ABC) Study. DESIGN:Observational cohort study. SETTING:Two U.S. communities...

journal_title：Journal of the American Geriatrics Society

authors： Newman AB,Kupelian V,Visser M,Simonsick E,Goodpaster B,Nevitt M,Kritchevsky SB,Tylavsky FA,Rubin SM,Harris TB,Health ABC Study Investigators.

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:To describe the prevalence and content of long-term care facility policies regarding the use of life-sustaining treatments (cardiopulmonary resuscitation (CPR), artificial hydration and nutrition, dialysis, antibiotics for life-threatening infections, transfer to acute care hospital) and advance directives in...

journal_title：Journal of the American Geriatrics Society

authors： Choudhry NK,Ma J,Rasooly I,Singer PA

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:To identify specific characteristics of patients, physicians, and treatment settings associated with decreased receipt of essential medications in a chronically ill, older population following a Medicaid three-prescription monthly reimbursement limit (cap). DESIGN:Quasi-experiment with bivariate and multivar...

journal_title：Journal of the American Geriatrics Society

authors： Fortess EE,Soumerai SB,McLaughlin TJ,Ross-Degnan D

更新日期：2001-06-01 00:00:00

abstract：:Long-term acute care (LTAC) represents a rapidly growing category of Medicare providers, but little is known about its quality, outcomes, and cost-effectiveness. Its defining characteristic, as set by Medicare, is an average length of stay of greater than 25 days. Modern LTAC emerged in the early 1980s as a setting fo...

journal_title：Journal of the American Geriatrics Society

authors： Eskildsen MA

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVES:To evaluate the effectiveness of wheelchair assessment and configuration on pressure injury incidence, mobility, and functioning in a wheelchair. DESIGN:Randomized controlled trial with participants individually randomized into intervention and control groups. SETTING:Nursing home. PARTICIPANTS:Nursing ho...

journal_title：Journal of the American Geriatrics Society

authors： Brienza DM,Karg PE,Bertolet M,Schmeler M,Poojary-Mazzotta P,Vlachos H,Wilkinson D

更新日期：2018-09-01 00:00:00

abstract：:Close to 6 million Americans have Alzheimer's disease (AD) or Alzheimer's disease and related dementia (AD/ADRD). These high-need, high-cost patients are vulnerable to receiving poor quality uncoordinated care, ultimately leading to adverse health outcomes, poor quality of life, and misuse of resources. Improving the ...

journal_title：Journal of the American Geriatrics Society

authors： Mitchell SL,Mor V,Harrison J,McCarthy EP

更新日期：2020-07-01 00:00:00

abstract：:To improve delirium recognition and care, numerous serum biomarkers have been investigated as potential tools for risk stratification, diagnosis, monitoring, and prognostication of delirium. The literature was reviewed, and no evidence was found to support the clinical use of any delirium biomarker, although certain b...

journal_title：Journal of the American Geriatrics Society

authors： Khan BA,Zawahiri M,Campbell NL,Boustani MA

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:To determine whether the characteristics of the usual medical care providers of older antidepressant users changed between 1986 and 1997 with the introduction of selective serotonin reuptake inhibitors. DESIGN:Longitudinal study. SETTING:Five-county Piedmont area of North Carolina. PARTICIPANTS:Stratified...

journal_title：Journal of the American Geriatrics Society

authors： Fillenbaum GG,Hybels CF,Pieper CF,Konrad TR,Burchett BM,Blazer DG

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVES:To identify risk factors for new-onset geriatric epilepsy that may trigger clinicians to consider a differential diagnosis of epilepsy at symptom onset. DESIGN:Retrospective cohort study. SETTING:National Veterans Affairs (VA) databases. PARTICIPANTS:Veterans aged 66 and older in fiscal year 2000 (FY00) w...

journal_title：Journal of the American Geriatrics Society

authors： Pugh MJ,Knoefel JE,Mortensen EM,Amuan ME,Berlowitz DR,Van Cott AC

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:To determine whether glycosylated hemoglobin (HbA1c) levels predict functional decline in older adults. DESIGN:Longitudinal cohort study. PARTICIPANTS:Community-dwelling, nursing home (NH)-eligible individuals with diabetes mellitus enrolled at On Lok between October 2002 and December 2008 (367 participant...

journal_title：Journal of the American Geriatrics Society

authors： Yau CK,Eng C,Cenzer IS,Boscardin WJ,Rice-Trumble K,Lee SJ

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVES:To determine the relationship between blood pressure (BP) and all-cause mortality in subjects aged 80 and older with hypertension. DESIGN:Retrospective cohort study with 5 years of follow-up. SETTING:Ten Veterans AFFAIRS (VA) sites. PARTICIPANTS:Four thousand seventy-one ambulatory patients aged 80 and ol...

journal_title：Journal of the American Geriatrics Society

authors： Oates DJ,Berlowitz DR,Glickman ME,Silliman RA,Borzecki AM

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To create a program to identify preventive needs for community-dwelling older persons and incorporate intervention strategies to improve implementation of these services. DESIGN:Program development and case-series. SETTING:Community-based meal sites, academically administered program. PARTICIPANTS:Persons ...

journal_title：Journal of the American Geriatrics Society

authors： Reuben DB,Hirsch SH,Frank JC,Maly RC,Schlesinger MS,Weintraub N,Yancey S

更新日期：1996-11-01 00:00:00

abstract：:In 1976, 130 patients aged 70 or older were admitted to the Coronary Care Unit (CCU) at Toronto Western Hospital. Arrhythmias were noted in all but 24 percent. Digoxin was given to 53 patients, lidocaine to 24, propranolol to 28, and quinidine to 11. In 2 patients, cardioversion by direct current was required for supr...

journal_title：Journal of the American Geriatrics Society

authors： Berman ND

更新日期：1979-05-01 00:00:00

abstract：:Neurotoxic effects of habitual alcohol consumption were investigated by correlating the subjects' estimates of abstinence or frequency and amount of alcohol consumed with measurements of gray matter blood flow utilizing the 133Xe inhalation method. Two hundred and twenty-two subjects were studied, including 136 health...

journal_title：Journal of the American Geriatrics Society

authors： Rogers RL,Meyer JS,Shaw TG,Mortel KF

更新日期：1983-09-01 00:00:00

abstract：OBJECTIVES:To examine associations between inflammation and physical function and potential mediation by white matter hyperintensities (WMHs) in African Americans (AAs) and European Americans (EAs). DESIGN:Cross-sectional analysis using linear and logistic models with generalized estimating equations to account for fa...

journal_title：Journal of the American Geriatrics Society

authors： Windham BG,Wilkening SR,Lirette ST,Kullo IJ,Turner ST,Griswold ME,Mosley TH Jr

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:To determine whether the occurrence of depression predicts physical disability in older people. DESIGN:A longitudinal epidemiological study with a follow-up of 5 years. SETTING:A comparison between depressed and nondepressed participants. PARTICIPANTS:The series consisted of the persons who participated i...

journal_title：Journal of the American Geriatrics Society

authors： Kivelä SL,Pahkala K

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVES:To examine the relationship between baseline hypertension, blood pressure, and the development of cognitive decline in participants in the Women's Health Initiative Memory Study (WHIMS). DESIGN:Prospective analyses. SETTING:Thirty-nine centers. PARTICIPANTS:Seven thousand one hundred forty-nine women aged...

journal_title：Journal of the American Geriatrics Society

authors： Johnson KC,Margolis KL,Espeland MA,Colenda CC,Fillit H,Manson JE,Masaki KH,Mouton CP,Prineas R,Robinson JG,Wassertheil-Smoller S,Women's Health Initiative Memory Study and Women's Health Initiative Investigators.

更新日期：2008-08-01 00:00:00

abstract：:There is accumulating evidence that interactions between beta-amyloid and copper, iron, and zinc are associated with the pathophysiology of Alzheimer's disease (AD). A significant dyshomeostasis of copper, iron, and zinc has been detected, and the mismanagement of these metals induces beta-amyloid precipitation and ne...

journal_title：Journal of the American Geriatrics Society

authors： Finefrock AE,Bush AI,Doraiswamy PM

更新日期：2003-08-01 00:00:00