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Functional mitral regurgitation: from normal to pathological anatomy of mitral valve.

Abstract：

:Mitral valve (MV) is composed of several structures working in synchrony to open during diastole and close in systole within the high-pressure systemic environment. Its morphological features ensure a normal leaflet closure that prevents regurgitation of blood back into the left atrium causing loss of ventricular pressure and forward flow. The complex interactions of the normal MV are reliant on each component playing a complete role for the efficient working of the valve. In this review we firstly discuss the overall MV structure in terms of a complex make up of the annulus, the leaflets, their tendinous cords, and the supporting papillary muscles, and then the anatomical changes of each MV components due to left ventricular geometry and function alterations, underlying functional mitral regurgitation.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Di Mauro M,Gallina S,D'Amico MA,Izzicupo P,Lanuti P,Bascelli A,Di Fonso A,Bartoloni G,Calafiore AM,Di Baldassarre A,Italian Group of Study for Heart Valve Disease (Italian Society of Cardiology).

doi

10.1016/j.ijcard.2011.11.023

subject

Has Abstract

pub_date

2013-03-10 00:00:00

pages

242-248

issue

3

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(11)02080-8

journal_volume

163

pub_type

杂志文章,评审

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