Abstract：
:Central obesity is closely linked to hypertension and type-2 diabetes (DM2) in young/middle-age. In the elderly, systolic hypertension is a reflection of aging/stiff arteries. Diastolic (± systolic) hypertension in young/middle-age is accompanied by increased sympathetic nerve activity, particularly in the presence of the metabolic syndrome or DM2. High beta-receptor density (Bmax) and cyclic AMP (cAMP) levels in human lymphocytes, independent of blood pressure, are associated with a high risk of myocardial infarction (not stroke-risk, which is dependent on blood pressure). This has treatment implications in the young/middle-aged hypertensive subject. Antihypertensive agents that increase sympathetic nerve activity e.g. dihydropyridine calcium blockers, angiotensin receptor blockers, and thiazide-type diuretics, do not reduce (and may increase) the risk of myocardial infarction. Beta-1 blockade, effective in reversing and stabilising coronary atheromataous plaque, and with possible anti-tumor properties, is superior to ACE-inhibition, and is the treatment of choice in young/middle-aged hypertension with DM2.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Coats AJ,Cruickshank JMdoi
10.1016/j.ijcard.2014.04.204subject
Has Abstractpub_date
2014-07-01 00:00:00pages
702-9issue
3eissn
0167-5273issn
1874-1754pii
S0167-5273(14)00886-9journal_volume
174pub_type
杂志文章,评审abstract：BACKGROUND:Type D personality has been associated with adverse outcomes in patients with coronary artery disease (CAD). However, large heterogeneity exists between Type D studies, including some studies reporting null-findings. OBJECTIVES:The aim of this study was to examine i) choice of endpoint and ii) age as two st...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2016.09.006
更新日期：2016-12-01 00:00:00
abstract：OBJECTIVES:We evaluate the crimping strain, sealing stress and contact forces on a Nitinol stent deployed in the aorta during endovascular aortic (or aneurysm) repair (EVAR) procedures. Nitinol shape memory effect (SME) is used. We also study the fluid-structure interaction (FSI) of the blood flow on the stented aorta....
journal_title：International journal of cardiology
pub_type： 杂志文章
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更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Exome sequencing is an established strategy to identify causal variants in families with two or more members affected by congenital heart disease (CHD). This unbiased approach, in which both rare and common variants are identified, makes it suitable to research complex, heterogeneous diseases such as CHD. M...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2016.12.024
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:The electrocardiographic (ECG) definition of Brugada syndrome (BS) can be challenging because benign ECG abnormalities, such as right bundle branch block (RBBB), may mimic pathological ECG characteristics of BrS. However, although myocardial delay and deformation can be quantified by advanced imaging, it has...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2020.06.029
更新日期：2020-12-01 00:00:00
abstract：:We describe the first reported case of rupture of a pseudoaneurysm of a sapheneous vein coronary arterial bypass graft presenting with acute superior caval venous obstruction. The patient was successfully treated by urgent surgical excision of the graft. ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(89)90171-x
更新日期：1989-10-01 00:00:00
abstract：:Calcium channel blockers (CCBs) have several properties which may have beneficial effects on the development of atherosclerosis. These include inhibition of vascular smooth muscle cell (SMC) proliferation and migration; inhibition of calcium influx into the vascular wall; reduction of extracellular matrix synthesis; p...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/s0167-5273(97)00236-2
更新日期：1997-12-31 00:00:00
abstract：BACKGROUND/OBJECTIVES:Therapy using bone marrow (BM) cells has been tested experimentally and clinically due to the potential ability to restore cardiac function by regenerating lost myocytes or increasing the survival of tissues at risk after myocardial infarction (MI). In this study we aimed to evaluate whether BM-de...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2013.06.026
更新日期：2013-10-09 00:00:00
abstract：BACKGROUND:After introduction of up-titration strategy, there are limited data on comparison between the effects of angiotensin converting enzyme inhibitors (ACEI) and angiotensin receptor blocker (ARB) in patients with heart failure with reduced ejection fraction (HFrEF). The study sought to investigate the associatio...
journal_title：International journal of cardiology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ijcard.2017.12.002
更新日期：2018-04-15 00:00:00
abstract：:A 15-year-old patient is presented with parasystolic ventricular tachycardia which was responsive to oral verapamil. We emphasize the value of verapamil in the treatment of this uncommon arrhythmia. ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(87)90300-7
更新日期：1987-04-01 00:00:00
abstract：BACKGROUND:The "cachectic heart" has been described as a pathologic decrease in the size and mass of the heart, but no in vivo studies have shown changes in cardiac dimensions or left ventricular (LV) mass over time in chronic heart failure (CHF) associated with body wasting (cardiac cachexia). Cardiovascular magnetic ...
journal_title：International journal of cardiology
pub_type： 杂志文章
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更新日期：2004-10-01 00:00:00
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journal_title：International journal of cardiology
pub_type： 信件
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更新日期：2003-06-01 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2019.07.019
更新日期：2019-12-01 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2015.06.009
更新日期：2015-11-01 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2016.07.178
更新日期：2016-11-01 00:00:00
abstract：INTRODUCTION:A number of challenges can affect long-term performance of endocardial implanted systems in pediatric patients. Select Secure™ lead offers potential advantages for this population. This analysis aims to evaluate long-term performance of this lead in children, with and without congenital heart disease. MET...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2018.01.007
更新日期：2018-03-15 00:00:00
abstract：:The effects of ACE inhibitors on the stenosed kidney in patients with unilateral arterial stenosis are not well characterised. While there are conflicting reports, some experimental and clinical evidence suggest that the stenosed kidney may undergo atrophy: secondary to effective blood pressure lowering and decreased ...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/0167-5273(95)02541-3
更新日期：1996-03-01 00:00:00
abstract：:In 24 subjects presenting with apparently idiopathic ventricular arrhythmias, a final diagnosis of arrhythmogenic right ventricular cardiomyopathy was formulated following global evaluation of the clinical, cross-sectional echocardiography and angiographic findings, and the observation of myocardial atrophy with fibro...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(92)90177-5
更新日期：1992-05-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Underuse of anticoagulants in ischemic stroke patients with atrial fibrillation (AF) and/or rheumatic heart disease (RHD) is a global concern, especially in China. However, the extent to which anticoagulants are underused in AF and/or RHD-related ischemic stroke in China has not been well charact...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2020.08.046
更新日期：2021-01-01 00:00:00
abstract：BACKGROUND:Whether converting to everolimus (EVL) from mycophenolate mofetil (MMF) during the maintenance period after heart transplantation (HTx) reduces cardiac allograft vasculopathy (CAV) progression remains unclear. We sought to determine the effect of converting from MMF with standard-dose calcineurin inhibitors ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2015.10.082
更新日期：2016-01-15 00:00:00
abstract：:We present an interesting case of paroxysmal hypertension in a young male caused by malignant pheochromocytoma. This patient, who had history of paroxysms of abdominal pain with severe hypertension, developed osseous metastasis in the first lumbar vertebra resulting in collapse of the vertebra and it caused paraplegia...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(92)90035-2
更新日期：1992-03-01 00:00:00
abstract：:After a documented decline in the incidence of acute rheumatic fever in the United States during the past three decades, an apparent resurgence has occurred in the mid-1980s. Although standards of living have continued to improve with concomitant decrease in crowding and easier accessibility to medical care, the preci...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/0167-5273(88)90003-4
更新日期：1988-10-01 00:00:00
abstract：AIM:The aim of our study was to compare the efficacy and safety of ibutilide and amiodarone (intravenously) in converting recent-onset atrial fibrillation (AF) and atrial flutter (Af) to sinus rhythm (SR). METHODS:The study was prospective, randomized and included 152 (103 men and 49 women) consecutive patients with A...
journal_title：International journal of cardiology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ijcard.2006.07.017
更新日期：2007-06-12 00:00:00
abstract：:A 78-year-old man was admitted with sudden onset of dyspnea followed by syncope. Contrast-enhanced computed tomography showed embolism in the right main pulmonary artery and left upper pulmonary artery. Echocardiography revealed a large, free-floating thrombus and cine magnetic resonance imaging showed highly mobile, ...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2007.06.140
更新日期：2008-09-26 00:00:00
abstract：BACKGROUND:The effects of adding moderate-to-high intensity inspiratory muscle training (IMT) to short-term aerobic and resistance exercise (combined training [CT]), after coronary artery bypass grafting (CABG) are not established. This study aimed to determine the effects of moderate-to-high intensity IMT + CT on exer...
journal_title：International journal of cardiology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ijcard.2018.12.013
更新日期：2019-03-15 00:00:00
abstract：BACKGROUND:The characteristics of unique ECG findings in the Brugada syndrome have not been well explained. METHODS:To clarify their characteristics and mechanisms, body surface maps (BSM) were recorded from patients with the Brugada syndrome (13 cases; a mean age of 48 years) before and after administration of isopro...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2003.05.025
更新日期：2004-06-01 00:00:00
abstract：:We describe the case of a 91-year-old man who presented with a large pericardial effusion and an intrapericardial mass. Primary malignant pericardial sarcoma was diagnosed by percutaneous pericardial tumor biopsy. The patient died of multiple organ failure three months later. We also review the epidemiology, clinical ...
journal_title：International journal of cardiology
pub_type： 信件,评审
doi：10.1016/j.ijcard.2008.03.097
更新日期：2009-07-24 00:00:00
abstract：:This investigation was carried out to compare the clinical course of patients with chronic Chagas' heart disease with that of patients with dilated cardiomyopathy. A total of 125 patients (75 chagasic and 50 nonchagasic) prospectively followed up at the Cardiomyopathy clinic of Santa Casa Hospital from January 1990 to...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/s0167-5273(97)00083-1
更新日期：1997-07-25 00:00:00
abstract：:We describe the case of a 42-year-old woman with a rare combination of congenital pericardial absence, atrial septal defect within the fossa ovalis and sick sinus syndrome. The features of the different examinations performed (chest X-ray, ECG, ambulatory ECG-monitoring, echocardiography, and cardiac catheterization) ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(84)90091-3
更新日期：1984-04-01 00:00:00
abstract：BACKGROUND:A proposed etiology of apical ballooning syndrome (ABS) is a spontaneously aborted anterior myocardial infarction (MI) in patients with a long "wrap around" left anterior descending artery (LAD) rather than it being a unique cardiomyopathy. The aim of this study was to evaluate whether patients with ABS have...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2009.06.018
更新日期：2010-11-05 00:00:00
abstract：BACKGROUND:Data with animal cells and models suggest that thrombin activates cardiac fibroblasts (Fib) to myofibroblasts (myoFib) via protease-activated receptor 1 (PAR1) cleavage, and in this way promotes adverse atrial remodeling and, thereby, atrial fibrillation (AF). OBJECTIVE:Here, we explored the effects of thro...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2018.05.033
更新日期：2018-11-15 00:00:00
