Abstract:
BACKGROUND:Type D personality has been associated with adverse outcomes in patients with coronary artery disease (CAD). However, large heterogeneity exists between Type D studies, including some studies reporting null-findings. OBJECTIVES:The aim of this study was to examine i) choice of endpoint and ii) age as two study characteristics that may partly explain this large heterogeneity in the Type D associated prognostic effect. METHODS:We used four existing data cohorts of 1503 CAD patients (89% male, mean age=57.2±9.1) with baseline measures of Type D and endpoints >5years follow-up: major adverse cardiac events (MACE), cardiac death/MI, and non-cardiac death. Patients were classified in 4 age categories: <50y, 50-59y, 60-69y and ≥70y. Multiple logistic regression models included age, sex, and clinical covariates. RESULTS:At follow-up, there were 295 events, including 116 cardiac death/MI, and 37 non-cardiac deaths. Both continuous and categorical measures of Type D predicted adverse events. Type D was independently associated with MACE (OR=1.82; 95%CI 1.33-2.50) and cardiac death/MI (OR=2.49; 95%CI 1.55-3.99). However, Type D was not associated with non-cardiac death (OR=1.23; 95%CI 0.57-2.69). Regarding age, Type D consistently predicted MACE in the lower age groups (all ORs≥2.20, all ps≤.004), but not in patients aged ≥70y (OR=1.43, p=.57). CONCLUSIONS:Choice of endpoint and age modulated the risk conferred by Type D personality. Type D was associated with an increased risk of cardiac events, but not with non-cardiac death, or with events in patients aged ≥70y. Research on psychosocial risk in CAD should account for different sources of heterogeneity in study characteristics.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Kupper N,Denollet Jdoi
10.1016/j.ijcard.2016.09.006subject
Has Abstractpub_date
2016-12-01 00:00:00pages
119-124eissn
0167-5273issn
1874-1754pii
S0167-5273(16)32150-7journal_volume
224pub_type
杂志文章abstract:BACKGROUND:Contrast-enhanced cardiac magnetic resonance imaging (MRI) can depict papillary muscle (PM) necrosis or fibrosis by late enhancement (LE) of PM, but its clinical significance in old myocardial infarction (OMI) has been little understood. METHODS:Myocardial LE and PM-LE were detected with contrast imaging in...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2010.04.037
更新日期:2011-01-07 00:00:00
abstract::Myocardial infarct size is one of the most important predictors of prognosis in patients suffering an acute myocardial infarction. It can be assessed by enzymatic and electrocardiographic methods. The present report compares dynamic vectorcardiographic monitoring, serial plasma enzyme activity measurements and QRS sco...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0167-5273(93)90280-t
更新日期:1993-07-01 00:00:00
abstract:BACKGROUND:Recent studies showed that J-waves are associated with vulnerability to ventricular fibrillation. Recently we reported the association between false tendons (FTs) and J-waves in a retrospective study. METHODS AND RESULTS:We prospectively studied 50 young healthy men (mean age 24.6±2.7 years). FTs were detec...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2014.01.101
更新日期:2014-03-15 00:00:00
abstract:BACKGROUND:The choice of antithrombotic prophylaxis in the so-called "medium-risk" patients (i.e., CHA2DS2-VASc score = 1 in males or 2 in females) is one of the major enigmatic issues in clinical management of atrial fibrillation (AF). METHODS:We retrospectively evaluated 30-day and 1-year thromboembolic events in al...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2019.04.057
更新日期:2019-08-01 00:00:00
abstract::We studied the effect of intravenous pirenzepine (3 mg) in normal subjects (n=15, 43+/-16 years old) and in patients with chronic heart failure (n=15, 61+/-12 years old) to assess the effect of low-dose pirenzepine on vagal activity. R-R intervals and the standard deviations, low-frequency power (LF: ln ms2, 0.04-0.15...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(98)00335-0
更新日期:1999-01-01 00:00:00
abstract::Exercise training has well documented beneficial effects in a variety of cardiac disorders. End stage renal disease patients present many cardiovascular complications and suffer from impaired exercise capacity. No study to date has adequately examined the cardiac responses to exercise training in renal patients on hem...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0167-5273(99)00090-x
更新日期:1999-08-31 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.11.144
更新日期:2017-02-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(00)00338-7
更新日期:2000-09-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
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更新日期:2009-08-14 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2019.05.003
更新日期:2019-08-15 00:00:00
abstract:PURPOSE:Aortic valve dysfunction is common in coarctation patients(CoA). Bicuspid aortic valve (BAV) in CoA is associated with aortic valve stenosis (AS), aortic valve regurgitation (AR), and ascending aortic dilatation. The aim of this study was to evaluate the progression of and predictors for aortic valve dysfunctio...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2012.07.028
更新日期:2013-09-10 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2011.02.073
更新日期:2012-09-06 00:00:00
abstract::We have the values of rest and maximal blood flow and of venous compliance in the forearm in three groups of patients: those undergoing orthotopic heart transplantation, those with severe cardiac insufficiency, and a control group. The findings suggest the presence of arteriolo- as well as venoconstriction in transpla...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(90)90163-y
更新日期:1990-05-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2014.08.003
更新日期:2014-10-20 00:00:00
abstract::Myocarditis was discovered as heart disease at autopsy with the use of microscope. In 1900, with the name of acute interstitial myocarditis, Carl Ludwig Alfred Fiedler first reported the history of a sudden cardiac heart failure, in the absence of coronary, valve, pericardial disease or classical specific infections w...
journal_title:International journal of cardiology
pub_type: 历史文章,杂志文章
doi:10.1016/j.ijcard.2019.07.046
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:In Marfan syndrome, the mitral valve prolapse, ranging from nonclassic to classic form on the basis of the leaflet thickness, is a common condition characterized by a highly variable structural abnormality. We investigated the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) I/D and a...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2006.12.015
更新日期:2008-01-24 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2008.02.019
更新日期:2008-10-13 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.07.125
更新日期:2016-10-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2009.11.031
更新日期:2011-05-05 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
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更新日期:2017-02-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 社论
doi:10.1016/s0167-5273(02)00426-6
更新日期:2003-05-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2012.09.097
更新日期:2013-09-20 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2013.10.022
更新日期:2013-12-10 00:00:00
abstract::Coronary perforation is a rare complication of percutaneous coronary intervention. We report a case of left anterior descending artery osteal perforation that led to acute cardiac tamponade during excimer laser angioplasty. Perforation was successfully covered with a PTFE-coated stent with preserved distal coronary fl...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/s0167-5273(02)00382-0
更新日期:2003-04-01 00:00:00
abstract:INTRODUCTION:Previous studies have established a relationship between socioeconomic status (SES) and survival in coronary heart disease. Acute cardiac care in Sweden is considered to be excellent and independent of SES. We studied the influence of area-level socioeconomic status on mortality after hospitalization for a...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2014.12.060
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Despite the increasing number of reports on lipomatous hypertrophy of interatrial septum, a standardization of measurement of the dimensions of the interatrial septum (IAS) in the different phases of cardiac cycle has not been reported. Moreover, no data on modification of thickness with age and in specific ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(95)02403-j
更新日期:1995-08-01 00:00:00
abstract:BACKGROUND:The role of anemia in heart failure with mid-range and preserved ejection fraction (HFmrEF, EF 40-49% and HFpEF, EF ≥50%) is unknown. We aimed to compare prevalence of, associations with, and prognostic role of anemia in HF across the EF spectrum. METHODS:In patients from the Swedish HF Registry, we assesse...
journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2020-01-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2015.12.015
更新日期:2016-02-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.01.034
更新日期:2018-04-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2011.10.011
更新日期:2013-06-05 00:00:00