Isozyme-specific effects of protein kinase C in pain modulation.

abstract：BACKGROUND:Densities in dependent lung regions worsen oxygenation in patients with acute respiratory distress syndrome. Identification of these densities requires examination using computed tomography (CT). In this study, the authors evaluated the use of transesophageal echocardiography (TEE) to estimate densities in t...

journal_title：Anesthesiology

authors： Tsubo T,Sakai I,Suzuki A,Okawa H,Ishihara H,Matsuki A

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Activation of the complement system is one component of the inflammatory response. Various components of the complement system participate in killing foreign organisms, recruiting immune cells, enhancing edema, and stimulating cytokine formation. Complement-mediated enhancement of the inflammation surroundin...

journal_title：Anesthesiology

authors： Clark JD,Qiao Y,Li X,Shi X,Angst MS,Yeomans DC

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Cerebrospinal fluid (CSF) outflow to intra- and extracranial subarachnoid spaces caused by arterial inflow to the brain predominantly compensates systolic increases in cerebral blood volume. Phase-contrast magnetic resonance imaging is a new tool for noninvasive assessment of CSF displacement by measuring CS...

journal_title：Anesthesiology

authors： Kolbitsch C,Schocke M,Lorenz IH,Kremser C,Zschiegner F,Pfeiffer KP,Felber S,Aichner F,Hörmann C,Benzer A

更新日期：1999-06-01 00:00:00

abstract：:Anesthesiologist-reviewers examined 1,175 anesthetic-related closed malpractice claims from 17 professional liability insurance companies. The claims were filed between 1974 and 1988. The reviewers were asked to determine if the negative outcome was preventable by proper use of additional monitoring devices available ...

journal_title：Anesthesiology

authors： Tinker JH,Dull DL,Caplan RA,Ward RJ,Cheney FW

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Since the effects of antiemetic doses of droperidol on the QT interval have not been previously studied, the authors designed a randomized, double-blind, placebo-controlled study to evaluate the intraoperative and postoperative effects of small-dose droperidol (0.625 and 1.25 mg intravenous) on the QT interv...

journal_title：Anesthesiology

authors： White PF,Song D,Abrao J,Klein KW,Navarette B

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Ethical conduct in human research in anesthesia includes approval by an institutional review board (IRB) or ethics committee and informed consent. Evidence of these is sometimes lacking in journal publications. METHODS:The authors reviewed all publications involving human subjects in six leading anesthesia ...

journal_title：Anesthesiology

authors： Myles PS,Tan N

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:The results of sevoflurane biotransformation (fluoromethyl-1,1,1,3,3,3,-hexafluoro-2-propyl ether) to inorganic fluoride have been examined. However, these investigations have lacked a simplified assay for determining the primary organic metabolite, hexafluoroisopropanol. Previous attempts have involved exte...

journal_title：Anesthesiology

authors： Morgan SE,Frink EJ,Gandolfi AJ

更新日期：1994-01-01 00:00:00

abstract：:Opioid receptors have been targeted for the treatment of pain and related disorders for thousands of years and remain the most widely used analgesics in the clinic. Mu (μ), kappa (κ), and delta (δ) opioid receptors represent the originally classified receptor subtypes, with opioid receptor like-1 (ORL1) being the leas...

journal_title：Anesthesiology

authors： Al-Hasani R,Bruchas MR

更新日期：2011-12-01 00:00:00

abstract：:Inorganic fluoride (F-) production and renal function were assessed in six groups of Fischer 344 rats administered either methoxyflurane (MOF) or deuterated methoxyflurane (d4-MOF). One untreated and one phenobarbital (PB)-treated group were exposed for two hours to either air, 0.5 per cent (V/v) MOF, or 0.5 per cent ...

journal_title：Anesthesiology

authors： Baden JM,Rice SA,Mazze RI

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:The objective of the survey was to assess the status of acute pain management in U.S. hospitals and attitudes of adults in the U.S. toward postoperative pain management, information that has not been previously available. METHODS:Two telephone questionnaire surveys were conducted U.S. hospital participants,...

journal_title：Anesthesiology

authors： Warfield CA,Kahn CH

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Victims of organophosphate intoxication with cholinergic crisis may have need for sedation and anesthesia, but little is known about how anesthetics work in these patients. Recent studies suggest that cholinergic stimulation impairs gamma-aminobutyric acid type A (GABAA) receptor function. Because GABAA rece...

journal_title：Anesthesiology

authors： Grasshoff C,Drexler B,Hentschke H,Thiermann H,Antkowiak B

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Multiport epidural catheters are popular; however, the reliability of the air test has not been evaluated with this catheter design. The authors determined the effectiveness of aspirating for blood and the air test in detecting intravascular multiorifice epidural catheters. METHODS:Three hundred women in la...

journal_title：Anesthesiology

authors： Leighton BL,Topkis WG,Gross JB,Arkoosh VA,Lee SH,Huffnagle HJ,Huffnagle SL

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Dysrhythmias and death occur in patients with acquired long QT syndrome (LQTS). Little information exists regarding interactions between anesthetics and drugs that prolong ventricular repolarization. Therefore the effects of three commonly used intravenous anesthetics on ventricular repolarization were inves...

journal_title：Anesthesiology

authors： Morey TE,Martynyuk AE,Napolitano CA,Raatikainen MJ,Guyton TS,Dennis DM

更新日期：1997-11-01 00:00:00

abstract：:The authors had previously observed a deleterious cerebrovascular effect of prolonged hypothermia in primates and cats. In this study they examined the systemic as well as cerebral hemodynamic and metabolic effects of 24 hours of hypothermia in the dog. With decreases in temperature to 29 C, cardiac output (Q) and who...

journal_title：Anesthesiology

authors： Steen PA,Milde JH,Michenfelder JD

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND:Our objective was to elucidate the direct effects of fentanyl and morphine on cardiac excitation-contraction coupling using individual, field-stimulated rat ventricular myocytes. METHODS:Freshly isolated myocytes were loaded with fura-2 and field stimulated (0.3 Hz) at 28 degrees C. Amplitude and timing of ...

journal_title：Anesthesiology

authors： Kanaya N,Zakhary DR,Murray PA,Damron DS

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Dynorphin A in the spinal cord is considered to contribute to nociceptive stimuli. However, it has not yet been determined whether activation of the spinal dynorphinergic system under nociceptive stimuli plays a role in direct acceleration of the ascending nociceptive pathway. In this study, the authors inve...

journal_title：Anesthesiology

authors： Taketa Y,Niikura K,Kobayashi Y,Furuya M,Shimizu T,Narita M,Imai S,Kuzumaki N,Maitani Y,Yamazaki M,Inada E,Iseki M,Suzuki T,Narita M

更新日期：2010-02-01 00:00:00

abstract：:Twenty-four patients survived life-threatening clinical anaphylaxis due to anesthesia. In each case the diagnosis of anaphylaxis was confirmed and the responsible drug was found by intradermal testing. To determine whether the reactions were anaphylactic or anaphylactoid, serum from each patient was tested for reagini...

journal_title：Anesthesiology

authors： Fisher MM

更新日期：1980-04-01 00:00:00

abstract：BACKGROUND:The aim of this study was to characterize cervical cord, root, and bony spine claims in the American Society of Anesthesiologists Closed Claims database to formulate hypotheses regarding mechanisms of injury. METHODS:All general anesthesia claims (1970-2007) in the Closed Claims database were searched to id...

journal_title：Anesthesiology

authors： Hindman BJ,Palecek JP,Posner KL,Traynelis VC,Lee LA,Sawin PD,Tredway TL,Todd MM,Domino KB

更新日期：2011-04-01 00:00:00

abstract：:The use of venovenous extracorporeal membrane oxygenation is increasing worldwide. These patients often require noncardiac surgery. In the perioperative period, preoperative assessment, patient transport, choice of anesthetic type, drug dosing, patient monitoring, and intraoperative and postoperative management of com...

journal_title：Anesthesiology

authors： Fierro MA,Daneshmand MA,Bartz RR

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Left ventricular diastolic function is known to be impaired in patients with coronary artery disease and patients with valvular aortic stenosis. Phenylephrine is frequently administered as an intravenous bolus in these patients perioperatively to increase coronary perfusion pressure. Although this is common ...

journal_title：Anesthesiology

authors： Goertz AW,Lindner KH,Schütz W,Schirmer U,Beyer M,Georgieff M

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine the relationship of four postanesthesia care unit (PACU) cardiovascular events to long-term outcomes (unplanned critical care admission or mortality) and to evaluate the contribution of anesthetic management compared with other perioperative factors in predicting th...

journal_title：Anesthesiology

authors： Rose DK,Cohen MM,DeBoer DP

更新日期：1996-04-01 00:00:00

abstract：:The neonatal neurobehavioral effects of bupivacaine, mepivacaine, and 2-chloroprocaine used in random sequence for pudendal block anesthesia were studied. The neurobehavioral status of 54 infants was studied 4 and 24 hours after delivery. Except for a significant difference in the responses to pinprick, there was no s...

journal_title：Anesthesiology

authors： Merkow AJ,McGuinness GA,Erenberg A,Kennedy RL

更新日期：1980-04-01 00:00:00

abstract：BACKGROUND:The decision to extubate brain-injured patients with residual impaired consciousness holds a high degree of uncertainty of success. The authors developed a pragmatic clinical score predictive of extubation failure in brain-injured patients. METHODS:One hundred and forty brain-injured patients were prospecti...

journal_title：Anesthesiology

authors： Godet T,Chabanne R,Marin J,Kauffmann S,Futier E,Pereira B,Constantin JM

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Aprotinin has been reported to reduce blood loss and transfusion requirements in patients having major orthopedic operations. Data on whether epsilon amino-caproic acid (EACA) is effective in this population are sparse. METHODS:Sixty-nine adults with malignancy scheduled for either pelvic, extremity or spin...

journal_title：Anesthesiology

authors： Amar D,Grant FM,Zhang H,Boland PJ,Leung DH,Healey JA

更新日期：2003-02-01 00:00:00

abstract：:The effect of pertussis toxin on opioid antinociception was studied in rats. Intrathecal injection of a single dose of pertussis toxin reduced the antinociceptive effect of PL017, a highly selective mu-opioid agonist, in a dose- and time-dependent manner. The maximal effective dose of pertussis toxin was 1 microgram, ...

journal_title：Anesthesiology

authors： Wong CS,Su YF,Chang KJ,Watkins WD

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Renal ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury and often leads to multiorgan dysfunction and systemic inflammation. Volatile anesthetics have potent antiinflammatory effects. We aimed to determine whether the representative volatile anesthetic isoflurane protects against acut...

journal_title：Anesthesiology

authors： Kim M,Park SW,Kim M,D'Agati VD,Lee HT

更新日期：2011-02-01 00:00:00

abstract：:Oral transmucosal fentanyl citrate (OTFC) is a novel, noninvasive dosage form of fentanyl used to provide children and adults with sedation, anxiolysis, and analgesia. In order to determine the bioavailability and absorption of fentanyl from OTFC, 12 volunteers were given intravenous fentanyl citrate or OTFC 15 microg...

journal_title：Anesthesiology

authors： Streisand JB,Varvel JR,Stanski DR,Le Maire L,Ashburn MA,Hague BI,Tarver SD,Stanley TH

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Conventional cardiopulmonary resuscitation (CPR) includes 80-100/min precordial compressions with intermittent positive pressure ventilation (IPPV) after every fifth compression. To prevent gastric insufflation, chest compressions are held during IPPV if the patient is not intubated. Elimination of IPPV woul...

journal_title：Anesthesiology

authors： Hevesi ZG,Thrush DN,Downs JB,Smith RA

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Propofol is an alternative to thiopental as an intravenous induction agent for cesarean section. Because it has relaxant effects on vascular and other smooth muscles, the authors set out to determine whether propofol has any effect on pregnant human uterine smooth muscle in an isolated preparation. METHODS:...

journal_title：Anesthesiology

authors： Shin YK,Kim YD,Collea JV

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:The distribution and elimination of 0.9% saline given by intravenous infusion has not been compared between the conscious state and during inhalational anesthesia. METHODS:Six adult sheep received an intravenous infusion of 25 ml/kg of 0.9% saline over 20 min in the conscious state and also during isofluran...

journal_title：Anesthesiology

authors： Brauer KI,Svensén C,Hahn RG,Traber LD,Prough DS

更新日期：2002-02-01 00:00:00