Abstract:
BACKGROUND:According to small studies carried out in preselected populations, the estimated prevalence of anti-hepatitis C virus (HCV) antibodies in Poland ranges from 0.6 to 2.1%. AIMS:The aim of this study was to evaluate the prevalence of anti-HCV and HCV RNA among patients and healthcare workers. METHODS:Anti-HCV antibodies were measured (Elecsys, Roche) in serum samples from 26,057 adults, consecutive patients or healthcare workers, from hospitals and out patient clinics not involved in the management of liver diseases. The majority of them (18,233) consented to fill out an anonymous questionnaire related to possible risk factors for HCV infection. Anti-HCV-positive samples were assessed for HCV RNA (Cobas Amplicor, Roche). A multivariate logistic regression model and the χ² test or the Fisher's exact test were applied. RESULTS:Anti-HCV antibodies were detected in 1.9% of individuals, and 31% of them demonstrated HCV RNA, which varied from 26% in hospitals to 66% in specialistic out-patient clinics. Prevalence of anti-HCV was significantly lower in healthcare workers (1.42%) than in patients (1.92%). Significant independent risk factors for anti-HCV positivity were as follows: male sex, more than three hospitalizations in a lifetime, blood transfusions before 1992, and intravenous drug use. The only significant risk factor for HCV RNA was intravenous drug use. An analysis carried out for multispecialistic hospitals demonstrated significantly lower prevalence of HCV RNA positivity in healthcare workers. CONCLUSION:Prevalence of anti-HCV in the Polish population studied was up to 1.9%, but active infection could be diagnosed in only 31% of them. Intravenous drug use, blood transfusions before 1992, multiple hospitalizations, and male sex increase the risk of HCV infection.
journal_name
Eur J Gastroenterol Hepatoljournal_title
European journal of gastroenterology & hepatologyauthors
Flisiak R,Halota W,Horban A,Juszczyk J,Pawlowska M,Simon Kdoi
10.1097/MEG.0b013e32834d173csubject
Has Abstractpub_date
2011-11-01 00:00:00pages
1213-7issue
12eissn
0954-691Xissn
1473-5687journal_volume
23pub_type
杂志文章,多中心研究abstract:INTRODUCTION:There is conflicting evidence on the benefit of early transjugular intrahepatic portosystemic shunt (TIPSS) on the survival of patients with acute variceal bleeding (AVB). AIM:To assess the effect of early TIPSS on patient prognosis. MATERIALS AND METHODS:We carried out a meta-analysis of trials evaluati...
journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MEG.0000000000000403
更新日期:2015-09-01 00:00:00
abstract:UNLABELLED:The role of duodenogastric reflux in gastrooesophageal reflux disease is still controversial. AIMS:(i) To determine the prevalence of pathological duodenogastric reflux (DGR) in gastrooesophageal reflux disease patients and (ii) to define the relationship between DGR and duodenogastrooesophageal reflux. ME...
journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/MEG.0b013e32830aba6d
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abstract:BACKGROUND AND OBJECTIVES:Early-onset colorectal cancer (eoCRC), defined as colorectal cancer (CRC) before the age of 50 is increasing in incidence. We evaluated exogenous and endogenous risk factors, and clinical features of eoCRC, compared to late-onset CRC (loCRC). METHODS:In this retrospective case-case study, pat...
journal_title:European journal of gastroenterology & hepatology
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章,多中心研究
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abstract:BACKGROUND:Little is known on gallbladder emptying and gallstone composition in the elderly. AIMS AND SUBJECTS: Cross-sectional survey on the prevalence of gallstone disease and associated factors, gallstone characteristics and gallbladder emptying in a population aged > or = 60 years. METHODS:Gallstone number and siz...
journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
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abstract:AIM:To assess the conclusiveness of the Cochrane Reviews (CRs) in the field of Pediatric-Gastroenterology. We tested the hypotheses that (a) the majority of CRs are inconclusive, (b) the majority of CRs recognize the need for further studies, (c) the ability to reach a conclusion is dependent on both the number of stud...
journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
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abstract::We present the case of a 23-year-old woman who presented with cytomegalovirus infection complicated by pancytopaenia, haemolysis and disseminated intravascular coagulopathy on a background diagnosis of coeliac crisis as the first presentation of coeliac disease. This is the first reported case of coeliac crisis presen...
journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/01.meg.0000224471.28626.a6
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVES:The factors associated with hepatitis C virus (HCV) treatment uptake and responses were assessed among HCV/HIV co-infected individuals referred for HCV therapy at an urban HIV clinic. METHODS:Retrospective review of HIV/HCV patients enrolled in the HCV treatment program at the John Ruedy Immunodeficiency Cl...
journal_title:European journal of gastroenterology & hepatology
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journal_title:European journal of gastroenterology & hepatology
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/00042737-200012080-00012
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:The outcome of primary biliary cholangitis (PBC) is affected by both genetic and environmental factors. OBJECTIVE:The aim of this study was to study the effect of smoking on liver histology and mortality in a genetically homogeneous population having PBC. PATIENTS AND METHODS:Smoking and drinking habits at...
journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
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更新日期:2018-12-01 00:00:00
abstract::Adult Still's disease is a well-characterized rheumatic disorder of unknown origin, which may affect multiple organs and may have a fatal course. However, liver failure has rarely been described in adult Still's disease. We present the case of a 25-year-old woman who was admitted with acute liver failure 2 years after...
journal_title:European journal of gastroenterology & hepatology
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更新日期:2003-01-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章,评审
doi:10.1097/00042737-199906000-00004
更新日期:1999-06-01 00:00:00
abstract:BACKGROUND:Hypermethylation of tumor suppressor genes' promoter and JC virus infection may be etiologic factors in the development of colorectal cancer (CRC). OBJECTIVES:To look at both JC virus T antigen and hMLH1 promoter methylation in CRC tissue in Israeli ethnic groups with different incidence of CRC. METHODS:Tw...
journal_title:European journal of gastroenterology & hepatology
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更新日期:2010-08-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
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更新日期:2008-09-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:1997-11-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章,随机对照试验
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更新日期:2015-08-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章,meta分析
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更新日期:2012-03-01 00:00:00
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更新日期:2010-07-01 00:00:00
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pub_type: 社论,评审
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章,多中心研究
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更新日期:2010-11-01 00:00:00
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pub_type: 杂志文章
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章,评审
doi:10.1097/00042737-199909000-00002
更新日期:1999-09-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
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更新日期:2020-07-29 00:00:00