Abstract:
:Automated methods of neonatal EEG seizure detection attempt to highlight the evolving, stereotypical, pseudo-periodic, nature of EEG seizure while rejecting the nonstationary, modulated, coloured stochastic background in the presence of various EEG artefacts. An important aspect of neonatal seizure detection is, therefore, the accurate representation and detection of pseudo-periodicity in the neonatal EEG. This paper describes a method of detecting pseudo-periodic components associated with neonatal EEG seizure based on a novel signal representation; the nonstationary frequency marginal (NFM). The NFM can be considered as an alternative time-frequency distribution (TFD) frequency marginal. This method integrates the TFD along data-dependent, time-frequency paths that are automatically extracted from the TFD using an edge linking procedure and has the advantage of reducing the dimension of a TFD. The reduction in dimension simplifies the process of estimating a decision statistic designed for the detection of the pseudo-periodicity associated with neonatal EEG seizure. The use of the NFM resulted in a significant detection improvement compared to existing stationary and nonstationary methods. The decision statistic estimated using the NFM was then combined with a measurement of EEG amplitude and nominal pre- and post-processing stages to form a seizure detection algorithm. This algorithm was tested on a neonatal EEG database of 18 neonates, 826 h in length with 1389 seizures, and achieved comparable performance to existing second generation algorithms (a median receiver operating characteristic area of 0.902; IQR 0.835-0.943 across 18 neonates).
journal_name
Med Eng Physjournal_title
Medical engineering & physicsauthors
Stevenson NJ,O'Toole JM,Rankine LJ,Boylan GB,Boashash Bdoi
10.1016/j.medengphy.2011.08.001subject
Has Abstractpub_date
2012-05-01 00:00:00pages
437-46issue
4eissn
1350-4533issn
1873-4030pii
S1350-4533(11)00199-8journal_volume
34pub_type
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