Comparison of pituitary-adrenocortical response to hypoglycaemia and surgery.

Abstract:

:The hypothalamic-pituitary-adrenocortical (HPA) responses to the hypoglycaemic stimulus and to operation (laparotomy) are compared. The studies were carried out in eight patients who were subjected to insulin-induced hypoglycaemia on the day before elective abdominal surgery. Plasma corticotrophin (ACTH) and plasma cortisol concentration increases were virtually indentical during the two procedures, which suggests that hypoglycaemia and surgical trauma are comparable stress factors and that the hypoglycaemia test is reliable in predicting the HPA responses to major surgical trauma.

authors

Blichert-Toft M,Christiansen C,Engquist A,Kehlet H,Lindholm J,Hummer L,Dinesen B

doi

10.1111/j.1399-6576.1979.tb01428.x

subject

Has Abstract

pub_date

1979-02-01 00:00:00

pages

103-6

issue

1

eissn

0001-5172

issn

1399-6576

journal_volume

23

pub_type

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