[Use of monoclonal antibodies in prophylaxis and treatment of acute and chronic graft-versus-host disease in 2011].

abstract：:An important critical point in tumor progression is the acquisition of metastatic potential. The presence of metastases in regional lymph nodes is an indicator of poor survival. The vascular endothelial growth factor (VEGF) family of growth factors and receptors is involved in vasculogenesis and angiogenesis. Among th...

journal_title：Bulletin du cancer

authors： Dupuy E,Tobelem G

更新日期：2003-07-01 00:00:00

abstract：:Irinotecan (CPT11), a topoisomerase I inhibitor, is a new cytotoxic agent with a broad spectrum of clinical activity. Two main schedules have been studied and produce similar activity and side-effects: the "european" one--350 mg/m2 every 21 days-, and the "japanese-north american" one where CPT11 is given at a weekly ...

journal_title：Bulletin du cancer

authors： Cottu PH,Extra JM,Lerebours F,Espie M,Marty M

更新日期：1998-12-01 00:00:00

abstract：:Breast cancer is the most common cancer among women with more than 53,000 new cases every year in France. The PI3K/AKT pathway is one of the major pathways involved in mammary tumorigenesis. The first effector of this pathway downstream Human Epidermal growth factor Receptor (HER receptors) is the enzyme phosphatidyl-...

journal_title：Bulletin du cancer

authors： Harlé A,Lion M,Lozano N,Merlin JL

更新日期：2013-10-01 00:00:00

abstract：:Colorectal cancer (CRC) is the second leading cause of cancer-related mortality in France. Recently, colorectal cancer subtyping consortium (CRCSC) identified 4 consensus molecular subtypes (CMS). CMS1 is enriched for CRC with deficient DNA mismatch repair system (dMMR) and tumors with mutated BRAF. Intriguingly, CMS1...

journal_title：Bulletin du cancer

authors： Cohen R,Cervera P,Svrcek M,Dumont C,Garcia ML,Chibaudel B,de Gramont A,Pocard M,Duval A,Fléjou JF,André T

更新日期：2015-06-01 00:00:00

abstract：:Since the results of bone marrow transplantation for acute leukemia in relapse have been poor (less than 20% long term survival), an attempt of bone marrow transplantation for acute leukemia in remission has been performed since 1976 by the Seattle Group. The results are very encouraging. In ANL transplanted in first ...

journal_title：Bulletin du cancer

authors： Buckner CD

更新日期：1981-01-01 00:00:00

abstract：:During the past two years, new molecular targets have been discovered which link cell cycle, cell proliferation and cellular growth. It has become more and more evident that whereas gain-of-function mutations in specific genes can lead to cancer, genomic instability plays also an important role in tumour progression. ...

journal_title：Bulletin du cancer

authors： Blanchard JM

更新日期：2002-01-01 00:00:00

abstract：:As compared to conventional axillary dissection, the sentinel node technique is accompanied by reduced morbidity and shorter hospital stay. Based on available data, the use of this technique does not seem to yield higher rates of axillary recurrence. A combination of both radioisotope detection and blue dye increases ...

journal_title：Bulletin du cancer

authors： Hindié E,Groheux D,Espie M,Bourstyn E,Toubert ME,Sarandi F,de Roquancourt A,Giacchetti S,Cuvier C,Cahen-Doidy L,Teyton P,Misset JL,Maylin C,Moretti JL

更新日期：2009-06-01 00:00:00

abstract：:We report on a case of 5-fluorouracil induced neurotoxicity during 5-fluorouracil cisplatin combination chemotherapy for advanced head and neck squamous cell carcinoma. The initial manifestations included an acute cerebellar syndrome and peripheral neuropathy. Computed tomography of the brain was normal. The results o...

journal_title：Bulletin du cancer

authors： Barbieux C,Patri B,Cerf I,de Parades V

更新日期：1996-01-01 00:00:00

abstract：:Since premedication of patients with an H1 antihistamine is recommended before the start of the intravenous infusion of temsirolimus, temsirolimus is to be used with caution in cases where there is a history of hypersensitivity to this class of antihistamines, or medical contra-indication for treatment with antihistam...

journal_title：Bulletin du cancer

authors： Massard C,Patard JJ,Hermine O,Ravaud A

更新日期：2011-01-01 00:00:00

abstract：:The antiestrogen tamoxifen (TAM) has been successfully used to treat breast cancer expressing estrogen and progesterone receptors (ER+ and PR+). However, the development of antiestrogen resistance is frequently observed in patients following long-term treatment. To better understand the mechanism of action of TAM and ...

journal_title：Bulletin du cancer

authors： Bachmann-Moisson N,Barberi-Heyob M,Merlin JL,Ledrich ML,Batt AM,Guillemin F

更新日期：1996-10-01 00:00:00

abstract：:Acute and chronic renal failures are very common after allogeneic HSCT. These complications have a real impact on mortality and morbidity of transplant recipients. Within the framework of the ninth workshops of practice harmonization of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-...

journal_title：Bulletin du cancer

authors： Detrait M,de Berranger E,Dulery R,Ménard AL,Thépot S,Toprak SK,Turlure P,Yakoub-Agha I,Guillaume T

更新日期：2020-01-01 00:00:00

abstract：:The purpose of external beam radiotherapy is to sterilize malignant tumours and at the same time to avoid complications by radiation injury to the surrounding healthy tissues. Modern radiation techniques in recent years have allowed to safely escalate the dose by approximately 10% for the treatment of prostate cancer,...

journal_title：Bulletin du cancer

authors： Soete G,Verellen D,Storme G

更新日期：2008-03-01 00:00:00

abstract：:In 2006, a total number of 149,000 cancer deaths were observed in France, 88,500 in the male population and 60,500 in the female population. In 2005, the number of new diagnoses of cancer is estimated to be 319,000, 183,000 among men and 136,000 among women. Age-standardised mortality rates are decreasing for most fre...

journal_title：Bulletin du cancer

authors： Guérin S,Doyon F,Hill C

更新日期：2009-01-01 00:00:00

abstract：:The treatment of metastatic melanoma is presently in complete revolution. Two molecules have recently been authorized for this indication. These treatments have a very different mechanism of action compared to previous chemotherapies. Vemurafenib is a targeted therapy, which blocks BRAF selectively. This molecule indu...

journal_title：Bulletin du cancer

authors： Mateus C,Robert C

更新日期：2012-06-01 00:00:00

abstract：:Localization of the sentinel lymph node (SLN) in digestive cancers was performed mainly for colorectal primaries and less frequently for oeso-gastric primaries. This technique is feasible in vivo or ex vivo, with a vital dye and/or with a radiolabeled marker. Technically, detection reliability is good, provided a few ...

journal_title：Bulletin du cancer

authors： Elias D,Lasser P,Duvillard P

更新日期：2002-06-01 00:00:00

abstract：:Through clearly identified molecular mechanisms, EGFR targeting leads to cell physiology modifications as cell proliferation, apoptosis and DNA repair. These mechanisms can explain the proper activity of EGFR targeting drugs but also represent a strong rational basis on which several experimental studies have been des...

journal_title：Bulletin du cancer

authors： Milano G,Magné N

更新日期：2003-11-01 00:00:00

abstract：CAR-T THERAPY:CURRENT USE IN THE UNITED STATES IN 2018: Treatment with T-cells engineered with chimeric antigen receptors (CAR T-cell therapy) has been a field of intense research in the United States since the 1980s. The recent approval in August 2017 of Kymriah (tisagenlecleucel) opened the door to broader access to ...

journal_title：Bulletin du cancer

authors： Gauthier J

更新日期：2018-12-01 00:00:00

abstract：:Superficial bladder tumor defined as pTa, pT1 and pTis stage is one of the most common cancer disease in the world. Intravesical BCGtherapy represents the best treatment when combined with transurethral resection to prevent tumor recurrence or progression and to lengthen the interval between recurrence. The toxicity i...

journal_title：Bulletin du cancer

authors： Prapotnich D

更新日期：1998-02-01 00:00:00

abstract：:Unusual aspect of the development of oxaliplatin was that substantial evidence of its activity was gathered when used in combination with protracted infusion of 5FU combined with leucovorin, preceeding the formal demonstration of its single activity in this disease. Phase II trials in previously treated patients by 5F...

journal_title：Bulletin du cancer

authors： André T,Louvet C,Maindrault-Goebel F,Gramont AD

更新日期：2001-08-01 00:00:00

abstract：:The rising incidence of cancers affecting the kidney emphasizes the need to identify the molecular pathways involved in the initiation and progression of kidney tumors in order to counter this phenomenon. For many years, genes belonging to the PAX family have been the focus of intensive studies in the fields of organo...

journal_title：Bulletin du cancer

authors： Béland M,Bouchard M

更新日期：2006-09-01 00:00:00

abstract：:Important progress have been recently achieved in the management of Hodgkin's disease (HD) and non-Hodgkin's lymphoma (NHL). Prognostic factors are now better defined in HD thanks to new biologic and radiologic information which complete old and relevant clinical factors. These parameters are expected to improve decis...

journal_title：Bulletin du cancer

authors： Eghbali H,Soubeyran P,Soubeyran I,Monnerau A,Cazorla S

更新日期：2002-01-01 00:00:00

abstract：:UPDATED 2016 RECOMMENDATIONS FOR THE CLINICAL PRACTICE OF NICE/SAINT-PAUL-DE-VENCE IN OVARIAN CANCER AND ADVANCED CERVICAL CANCER: Since the first edition of the 2012-2013 Clinical Practice Recommendations Nice-Saint-Paul for gynecological cancers, the management of ovarian cancer has become more complex with a better...

journal_title：Bulletin du cancer

authors： Joly F,Querleu D,Namer M,Pujade-Lauraine E

更新日期：2017-05-01 00:00:00

abstract：INTRODUCTION:The French Patient Advocacy Group SOS Desmoid conducted a survey to measure the pain burden of desmoid tumor patients. MATERIAL AND METHODS:We used a structured questionnaire to measure the occurrence and consequences of pain. RESULTS:The pain occurrence was approximately 63%. In one-third of the cases, ...

journal_title：Bulletin du cancer

authors： Rigaux P,Lefebvre-Kuntz D,Penel N,“SOS Desmoïde”.

更新日期：2015-03-01 00:00:00

abstract：:We report a case of renal cell carcinoma presenting with bilateral adrenal masses diagnosed by ultrasonography four years after nephrectomy. The histopathological examination of the trucut biopsy specimens obtained percutaneously by ultrasound guidance revealed bilateral adrenal mestastases of renal cell carcinoma. ...

journal_title：Bulletin du cancer

authors： Sahin A,Ozen H,Ozmen M,Remzi D

更新日期：1994-02-01 00:00:00

abstract：:The dependency between the risk of death and age is analysed, and the contribution of cancer to the overall risk of death is evaluated as a function of age. The frequency of the different cancer sites is described in different age groups. Lastly cancer mortality trends are presented by age. The risk of death from canc...

journal_title：Bulletin du cancer

authors： Hill C,Doyon F

更新日期：2008-05-28 00:00:00

abstract：:Iatrogenic pain is a common problem for cancer patients, including those due to hospital internal transport. An original prospective study conducted in 2006 allowed risk factor identification, and from 2007, a pluri-annual progress plan was implemented. Its actions were systematically evaluated and all phases of trans...

journal_title：Bulletin du cancer

authors： Nebbak JM,Vignozzi A,Bussy C,Charleux D,Laplanche A,Mathivon D,Di Palma M

更新日期：2013-07-01 00:00:00

abstract：:Cytogenetic, molecular and phenotyping features of malignant hematologic diseases succeeded in improving their management by a more accurate stratification of patients according to several groups of risk and by providing a rational for targeted therapy. Three major types of treatment (excluding cellular therapy) are c...

journal_title：Bulletin du cancer

authors： Baleydier F,Domenech C,Thomas X

更新日期：2011-08-01 00:00:00

abstract：:In an attempt to harmonize clinical practices among French hematopoietic stem cell transplantation centers, the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) held its sixth annual workshop series in September 2015 in Lille. This event brought together practitioners from across the c...

journal_title：Bulletin du cancer

authors： Dubois V,Brignier A,Elsermans V,Gagne K,Kennel A,Pedron B,Picard C,Ravinet A,Varlet P,Cesbron A,Delbos F,Yakoub-Agha I,Loiseau P

更新日期：2016-11-01 00:00:00

abstract：:The anticancer drug technical commission (COTECH) of the Auvergne OMEDIT has set up a region-wide professional practice evaluation (PPE) with regards to antiemetic prescription practices in chemotherapy-induced nausea and vomiting (CINV), in order to evaluate their compliance with OMEDIT's guidelines. Are not included...

journal_title：Bulletin du cancer

authors： Tavernier J,Jouannet-Romaszko M,Bertucat H,Marchiset N,Bahadoor M,Chevrier R

更新日期：2016-07-01 00:00:00

abstract：:From 1941, estrogens are usually used in the treatment of prostatic carcinoma, wrongly in case of adjuvant hormonotherapy and exceedingly because of cardiovascular toxicity from over dosages. A recall of their mechanism of action and toxicity allows to argue about the palliative treatment and to look to their use for ...

journal_title：Bulletin du cancer

authors： Mauriac L,Richaud P,Mage P,Thomas L,Lamarche P

更新日期：1986-01-01 00:00:00